Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.1 0.232 0.586 48.0 -9999.0 0.0 48.0 KIRREL -0.012 0.076 -9999.0 0.0 -0.836 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.1 0.233 -9999.0 0.0 -0.587 48.0 48.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.127 0.199 -9999.0 0.0 -0.544 38.0 38.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.075 0.155 -9999.0 0.0 -0.534 9.0 9.0 FYN -0.105 0.194 -9999.0 0.0 -0.499 38.0 38.0 mol:Ca2+ -0.126 0.197 -9999.0 0.0 -0.538 38.0 38.0 mol:DAG -0.127 0.198 -9999.0 0.0 -0.541 38.0 38.0 NPHS2 -0.106 0.212 -9999.0 0.0 -0.524 55.0 55.0 mol:IP3 -0.127 0.198 -9999.0 0.0 -0.541 38.0 38.0 regulation of endocytosis -0.092 0.184 -9999.0 0.0 -0.467 38.0 38.0 Nephrin/NEPH1/podocin/Cholesterol -0.13 0.202 -9999.0 0.0 -0.551 38.0 38.0 establishment of cell polarity -0.1 0.232 -9999.0 0.0 -0.586 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.115 0.182 -9999.0 0.0 -0.5 38.0 38.0 Nephrin/NEPH1/beta Arrestin2 -0.093 0.187 -9999.0 0.0 -0.474 38.0 38.0 NPHS1 -0.126 0.293 -9999.0 0.0 -0.76 46.0 46.0 Nephrin/NEPH1/podocin -0.105 0.195 -9999.0 0.0 -0.502 38.0 38.0 TJP1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.127 0.199 -9999.0 0.0 -0.544 38.0 38.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.127 0.199 -9999.0 0.0 -0.544 38.0 38.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.1 0.194 -9999.0 0.0 -0.503 38.0 38.0 cytoskeleton organization -0.09 0.191 -9999.0 0.0 -0.661 9.0 9.0 Nephrin/NEPH1 -0.073 0.175 -9999.0 0.0 -0.494 37.0 37.0 Nephrin/NEPH1/ZO-1 -0.088 0.187 -9999.0 0.0 -0.546 36.0 36.0