Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.018 0.093 0.212 43.0 -9999.0 0.0 43.0 KIRREL 0.004 0.042 -9999.0 0.0 -0.269 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.018 0.094 -9999.0 0.0 -0.212 43.0 43.0 PLCG1 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.017 0.119 -9999.0 0.0 -0.207 62.0 62.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.038 0.098 -9999.0 0.0 -0.211 59.0 59.0 FYN -0.04 0.105 0.208 12.0 -0.2 59.0 71.0 mol:Ca2+ -0.017 0.11 -9999.0 0.0 -0.204 52.0 52.0 mol:DAG -0.016 0.111 -9999.0 0.0 -0.205 52.0 52.0 NPHS2 -0.061 0.155 -9999.0 0.0 -0.365 55.0 55.0 mol:IP3 -0.016 0.111 -9999.0 0.0 -0.205 52.0 52.0 regulation of endocytosis -0.021 0.104 -9999.0 0.0 -0.189 58.0 58.0 Nephrin/NEPH1/podocin/Cholesterol -0.028 0.111 -9999.0 0.0 -0.201 64.0 64.0 establishment of cell polarity -0.018 0.093 -9999.0 0.0 -0.212 43.0 43.0 Nephrin/NEPH1/podocin/NCK1-2 -0.008 0.117 -9999.0 0.0 -0.191 58.0 58.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.105 -9999.0 0.0 -0.191 58.0 58.0 NPHS1 -0.036 0.116 -9999.0 0.0 -0.296 42.0 42.0 Nephrin/NEPH1/podocin -0.025 0.107 -9999.0 0.0 -0.198 62.0 62.0 TJP1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.015 0.112 -9999.0 0.0 -0.206 52.0 52.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.12 -9999.0 0.0 -0.207 62.0 62.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.05 0.097 0.215 12.0 -0.189 58.0 70.0 cytoskeleton organization -0.051 0.106 0.21 3.0 -0.234 60.0 63.0 Nephrin/NEPH1 -0.006 0.065 -9999.0 0.0 -0.14 43.0 43.0 Nephrin/NEPH1/ZO-1 -0.001 0.082 -9999.0 0.0 -0.197 18.0 18.0