Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.027 0.103 0.301 1.0 -0.346 9.0 10.0 MAP3K8 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 FOS 0.016 0.089 0.315 1.0 -0.337 8.0 9.0 PRKCA 0.025 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.022 0.029 -9999.0 0.0 -0.279 2.0 2.0 HRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.008 0.078 -9999.0 0.0 -0.352 12.0 12.0 NRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.041 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.019 0.076 -9999.0 0.0 -0.451 5.0 5.0 MAP2K1 0.007 0.08 -9999.0 0.0 -0.347 9.0 9.0 ELK1 0.025 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.002 0.068 -9999.0 0.0 -0.319 11.0 11.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 12.0 12.0 MAPK1 0.014 0.093 -9999.0 0.0 -0.453 8.0 8.0 RAF1 0.001 0.079 -9999.0 0.0 -0.379 10.0 10.0 KRAS 0.024 0.009 -9999.0 0.0 -9999.0 0.0 0.0