Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
PPP2R1A	27 (11%)	221	0.075984	1	0.0518	1	0.028352	1	0.012146	1	0.1409	1	0.31271	1	0.053109	1	0.0097397	1	0.066496	1	0.0051951	1
PIK3CA	132 (53%)	116	0.85887	1	0.20272	1	0.52851	1	0.67774	1	0.36637	1	0.36468	1	0.5725	1	0.52288	1	0.40099	1	0.50229	1
CTNNB1	74 (30%)	174	4.9035e-07	0.000166	0.0011513	0.378	2.5692e-05	0.00861	0.0032669	1	1.289e-10	4.43e-08	0.11185	1	4.2124e-11	1.45e-08	0.011454	1	0.019599	1	9.1293e-06	0.00308
PIK3R1	83 (33%)	165	0.06672	1	0.02209	1	0.0051484	1	3.2206e-05	0.0108	0.6489	1	0.87686	1	0.0062662	1	0.014444	1	0.014661	1	0.0024926	0.805
PRKAR1B	4 (2%)	244	NA	NA	NA	NA	0.98986	1	0.50869	1	0.88699	1	1	1	0.50621	1	0.11607	1	0.78908	1	0.69145	1
PTEN	161 (65%)	87	0.0042787	1	0.0003568	0.118	1.4473e-20	5.11e-18	1.43e-12	4.96e-10	0.025685	1	0.18335	1	1.0733e-13	3.76e-11	1.8723e-12	6.48e-10	1.2087e-09	4.15e-07	5.922e-13	2.07e-10
RPL22	31 (12%)	217	0.053072	1	0.16015	1	0.011582	1	0.0086183	1	0.015268	1	0.26035	1	0.43822	1	0.049612	1	0.21312	1	0.90059	1
KRAS	53 (21%)	195	0.203	1	0.00074173	0.244	0.003496	1	0.11892	1	0.29674	1	0.85484	1	0.001229	0.402	0.92225	1	0.042068	1	0.20863	1
TP53	69 (28%)	179	3.8766e-05	0.0129	1.7188e-07	5.84e-05	1.047e-28	3.71e-26	1.1308e-12	3.94e-10	2.0063e-05	0.00674	0.0014012	0.457	2.2493e-16	7.92e-14	6.8045e-15	2.39e-12	3.6834e-09	1.26e-06	8.1696e-09	2.79e-06
FBXW7	39 (16%)	209	0.225	1	0.69213	1	0.33912	1	0.067729	1	0.10644	1	0.10694	1	0.044226	1	0.14661	1	0.35602	1	0.079813	1
CTCF	45 (18%)	203	0.14875	1	0.42097	1	0.00016892	0.0559	0.048104	1	0.078376	1	0.84803	1	0.0083362	1	0.0023317	0.755	0.01159	1	0.1339	1
ARID1A	83 (33%)	165	0.26532	1	0.011471	1	5.3655e-06	0.00181	0.23285	1	0.02713	1	1	1	0.04785	1	0.0089872	1	0.020397	1	0.14358	1
SPOP	21 (8%)	227	0.34932	1	1	1	0.90918	1	0.35577	1	0.83433	1	0.41497	1	0.033696	1	0.65375	1	0.60577	1	0.79895	1
ARID5B	29 (12%)	219	0.96088	1	0.45933	1	0.049961	1	0.13611	1	0.16398	1	0.1818	1	0.062224	1	0.40657	1	0.34234	1	0.59282	1
FGFR2	31 (12%)	217	0.38513	1	0.29313	1	0.36416	1	0.89732	1	0.96987	1	0.82869	1	0.91083	1	0.049203	1	0.64696	1	1	1
CCND1	15 (6%)	233	0.631	1	0.83347	1	0.12352	1	0.49484	1	0.37433	1	0.33848	1	0.059526	1	0.21014	1	0.4298	1	0.75726	1
SMTNL2	9 (4%)	239	NA	NA	NA	NA	0.18814	1	0.58805	1	0.60253	1	1	1	0.83075	1	0.023487	1	0.78908	1	1	1
NFE2L2	15 (6%)	233	0.090516	1	0.83347	1	0.0020066	0.652	0.63063	1	0.2479	1	1	1	0.53818	1	0.62012	1	0.34234	1	0.59282	1
CHD4	35 (14%)	213	0.098645	1	0.28356	1	0.5505	1	0.90668	1	0.96961	1	0.28657	1	0.56283	1	0.69768	1	0.47098	1	0.95098	1
RBMX	13 (5%)	235	0.1912	1	0.17985	1	0.23314	1	0.38554	1	0.01243	1	1	1	0.091162	1	0.10552	1	0.81334	1	0.8676	1
FAM9A	14 (6%)	234	NA	NA	NA	NA	0.8396	1	0.26967	1	0.17795	1	0.022725	1	0.38413	1	0.03293	1	0.026613	1	0.2253	1
MORC4	20 (8%)	228	0.58319	1	0.17985	1	0.065075	1	0.27973	1	0.21229	1	0.033158	1	0.34106	1	0.11867	1	0.31727	1	0.5616	1
HPD	7 (3%)	241	NA	NA	NA	NA	0.56351	1	0.77578	1	0.44673	1	0.65085	1	0.041105	1	0.59179	1	1	1	1	1
CASP8	17 (7%)	231	0.38127	1	0.059544	1	0.11909	1	0.62611	1	0.15421	1	0.26865	1	0.13446	1	0.030982	1	0.46366	1	1	1
FOXA2	12 (5%)	236	NA	NA	NA	NA	0.50671	1	0.7954	1	0.071861	1	0.74395	1	0.055138	1	1	1	0.67802	1	0.77752	1
ABI1	4 (2%)	244	NA	NA	NA	NA	0.82055	1	NA	NA	0.64001	1	0.63688	1	0.66951	1	0.70235	1	NA	NA	NA	NA
DNER	18 (7%)	230	0.1912	1	0.051469	1	0.003333	1	0.59682	1	0.021717	1	0.58145	1	0.75076	1	0.016757	1	1	1	0.88124	1
BCOR	30 (12%)	218	0.68711	1	0.4049	1	0.0079845	1	0.025261	1	0.51211	1	0.50027	1	0.026957	1	0.045761	1	0.86345	1	0.4402	1
BRS3	15 (6%)	233	0.53592	1	0.15102	1	0.15014	1	0.51936	1	0.3924	1	0.54035	1	0.14269	1	0.03293	1	0.55078	1	0.58913	1
NRAS	9 (4%)	239	NA	NA	NA	NA	0.64494	1	NA	NA	0.31592	1	1	1	0.58935	1	0.35733	1	NA	NA	NA	NA
SGK1	15 (6%)	233	0.38127	1	0.059544	1	0.059751	1	0.62525	1	0.22598	1	0.095402	1	0.28772	1	0.60088	1	0.81334	1	0.8676	1
TIAL1	11 (4%)	237	0.38127	1	0.4049	1	0.30262	1	0.063416	1	0.56444	1	0.74395	1	0.55112	1	0.50847	1	0.34234	1	0.7247	1
RPL14	7 (3%)	241	NA	NA	NA	NA	0.90239	1	0.87432	1	0.47879	1	1	1	0.34324	1	1	1	1	1	1	1
SIN3A	21 (8%)	227	NA	NA	NA	NA	0.0047877	1	0.60399	1	0.0060674	1	0.1293	1	0.19048	1	0.00011581	0.0384	0.51091	1	0.45743	1
SLC48A1	5 (2%)	243	NA	NA	NA	NA	0.7363	1	0.63905	1	0.80339	1	0.37153	1	0.88647	1	0.51692	1	0.78908	1	0.69145	1
ZFHX3	44 (18%)	204	0.37543	1	0.029852	1	0.045083	1	0.06291	1	0.31768	1	0.1793	1	0.13904	1	0.78891	1	0.53606	1	0.9743	1
RNF43	12 (5%)	236	0.13313	1	0.15102	1	0.21491	1	0.3775	1	0.29629	1	1	1	0.12837	1	0.068751	1	0.3382	1	0.26213	1
ZNF263	8 (3%)	240	0.02425	1	0.059544	1	0.48266	1	0.38554	1	0.61054	1	1	1	0.46375	1	1	1	0.4298	1	0.58913	1