Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.09 0.178 0.412 27.0 -0.236 2.0 29.0 KIRREL -0.126 0.238 -9999.0 0.0 -0.563 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.09 0.178 0.237 2.0 -0.413 27.0 29.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.065 0.131 -9999.0 0.0 -0.3 27.0 27.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.06 0.119 -9999.0 0.0 -0.275 26.0 26.0 FYN -0.064 0.121 -9999.0 0.0 -0.285 27.0 27.0 mol:Ca2+ -0.065 0.129 -9999.0 0.0 -0.298 27.0 27.0 mol:DAG -0.065 0.13 -9999.0 0.0 -0.299 27.0 27.0 NPHS2 -0.01 0.024 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.065 0.13 -9999.0 0.0 -0.299 27.0 27.0 regulation of endocytosis -0.057 0.116 -9999.0 0.0 -0.265 27.0 27.0 Nephrin/NEPH1/podocin/Cholesterol -0.066 0.132 0.199 2.0 -0.305 27.0 29.0 establishment of cell polarity -0.09 0.178 0.236 2.0 -0.412 27.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.061 0.125 -9999.0 0.0 -0.281 27.0 27.0 Nephrin/NEPH1/beta Arrestin2 -0.058 0.117 0.198 2.0 -0.267 27.0 29.0 NPHS1 0.001 0.06 0.345 3.0 -9999.0 0.0 3.0 Nephrin/NEPH1/podocin -0.062 0.125 0.201 2.0 -0.287 27.0 29.0 TJP1 -0.005 0.051 -9999.0 0.0 -0.56 1.0 1.0 NCK1 -0.005 0.051 -9999.0 0.0 -0.56 1.0 1.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.065 0.131 -9999.0 0.0 -0.3 27.0 27.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.065 0.131 -9999.0 0.0 -0.3 27.0 27.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.085 0.155 -9999.0 0.0 -0.326 31.0 31.0 cytoskeleton organization -0.067 0.131 -9999.0 0.0 -0.306 26.0 26.0 Nephrin/NEPH1 -0.063 0.127 0.194 2.0 -0.291 27.0 29.0 Nephrin/NEPH1/ZO-1 -0.074 0.149 0.209 2.0 -0.337 27.0 29.0