Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.051 0.165 0.38 23.0 -0.26 1.0 24.0 KIRREL -0.087 0.217 -9999.0 0.0 -0.516 24.0 24.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.051 0.166 0.26 1.0 -0.381 23.0 24.0 PLCG1 0.023 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.022 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.018 0.136 -9999.0 0.0 -0.294 21.0 21.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.042 0.114 -9999.0 0.0 -0.271 20.0 20.0 FYN -0.025 0.151 0.27 12.0 -0.279 21.0 33.0 mol:Ca2+ -0.019 0.134 -9999.0 0.0 -0.291 21.0 21.0 mol:DAG -0.019 0.135 -9999.0 0.0 -0.292 21.0 21.0 NPHS2 -0.016 0.035 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.019 0.135 -9999.0 0.0 -0.292 21.0 21.0 regulation of endocytosis -0.022 0.12 -9999.0 0.0 -0.264 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol -0.028 0.13 0.229 1.0 -0.285 23.0 24.0 establishment of cell polarity -0.051 0.165 0.26 1.0 -0.38 23.0 24.0 Nephrin/NEPH1/podocin/NCK1-2 -0.01 0.14 -9999.0 0.0 -0.29 20.0 20.0 Nephrin/NEPH1/beta Arrestin2 -0.021 0.122 -9999.0 0.0 -0.267 21.0 21.0 NPHS1 0.003 0.063 0.358 2.0 -9999.0 0.0 2.0 Nephrin/NEPH1/podocin -0.023 0.127 0.23 1.0 -0.276 22.0 23.0 TJP1 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.019 0.049 -9999.0 0.0 -0.512 1.0 1.0 NCK2 0.025 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.018 0.136 -9999.0 0.0 -0.293 21.0 21.0 CD2AP 0.024 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.135 -9999.0 0.0 -0.293 21.0 21.0 GRB2 0.023 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.041 0.172 0.278 11.0 -0.318 23.0 34.0 cytoskeleton organization -0.055 0.132 0.277 1.0 -0.313 20.0 21.0 Nephrin/NEPH1 -0.032 0.118 0.212 1.0 -0.266 23.0 24.0 Nephrin/NEPH1/ZO-1 -0.032 0.142 0.243 1.0 -0.313 23.0 24.0