Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.011	0.146	0.38	3.0	-0.678	1.0	4.0
IHH	-0.021	0.259	0.369	15.0	-0.531	20.0	35.0
SHH Np/Cholesterol/GAS1	-0.064	0.148	0.295	1.0	-0.324	26.0	27.0
LRPAP1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.064	0.147	0.322	26.0	-0.292	1.0	27.0
SMO/beta Arrestin2	-0.034	0.174	-9999.0	0.0	-0.383	18.0	18.0
SMO	-0.049	0.176	-9999.0	0.0	-0.395	19.0	19.0
AKT1	-0.009	0.109	-9999.0	0.0	-0.411	3.0	3.0
ARRB2	0.022	0.009	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.025	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.044	0.176	-9999.0	0.0	-0.39	19.0	19.0
STIL	-0.042	0.165	0.281	4.0	-0.406	9.0	13.0
DHH N/PTCH2	0.026	0.095	0.27	4.0	-0.377	5.0	9.0
DHH N/PTCH1	-0.019	0.152	-9999.0	0.0	-0.303	22.0	22.0
PIK3CA	0.021	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.001	0.108	-9999.0	0.0	-0.512	5.0	5.0
PTHLH	-0.011	0.17	0.456	3.0	-0.494	2.0	5.0
determination of left/right symmetry	-0.044	0.176	-9999.0	0.0	-0.39	19.0	19.0
PIK3R1	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.011	0.169	0.455	3.0	-0.49	2.0	5.0
IHH N/Hhip	-0.024	0.203	0.284	1.0	-0.391	23.0	24.0
DHH N/Hhip	-0.007	0.139	0.27	2.0	-0.4	12.0	14.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.044	0.176	-9999.0	0.0	-0.39	19.0	19.0
pancreas development	-0.009	0.144	0.381	2.0	-0.511	8.0	10.0
HHAT	0.017	0.05	-9999.0	0.0	-0.512	1.0	1.0
PI3K	0.03	0.015	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.045	0.178	-9999.0	0.0	-0.512	15.0	15.0
somite specification	-0.044	0.176	-9999.0	0.0	-0.39	19.0	19.0
SHH Np/Cholesterol/PTCH1	-0.047	0.162	0.292	1.0	-0.316	26.0	27.0
SHH Np/Cholesterol/PTCH2	-0.019	0.125	0.289	5.0	-0.296	16.0	21.0
SHH Np/Cholesterol/Megalin	-0.19	0.18	0.295	1.0	-0.331	67.0	68.0
SHH	-0.059	0.135	0.504	1.0	-0.377	16.0	17.0
catabolic process	-0.019	0.15	0.308	3.0	-0.322	20.0	23.0
SMO/Vitamin D3	-0.042	0.196	0.306	3.0	-0.386	20.0	23.0
SHH Np/Cholesterol/Hhip	-0.043	0.15	0.29	3.0	-0.35	19.0	22.0
LRP2	-0.287	0.263	-9999.0	0.0	-0.512	68.0	68.0
receptor-mediated endocytosis	-0.178	0.224	0.281	1.0	-0.493	28.0	29.0
SHH Np/Cholesterol/BOC	-0.029	0.11	0.295	1.0	-0.296	16.0	17.0
SHH Np/Cholesterol/CDO	-0.043	0.122	0.295	1.0	-0.296	21.0	22.0
mesenchymal cell differentiation	0.043	0.148	0.348	19.0	-0.287	3.0	22.0
mol:Vitamin D3	-0.026	0.182	0.311	3.0	-0.32	25.0	28.0
IHH N/PTCH2	0.009	0.17	0.279	5.0	-0.325	20.0	25.0
CDON	0.001	0.108	-9999.0	0.0	-0.512	5.0	5.0
IHH N/PTCH1	-0.0	0.167	0.346	3.0	-0.326	20.0	23.0
Megalin/LRPAP1	-0.202	0.201	-9999.0	0.0	-0.376	67.0	67.0
PTCH2	0.036	0.065	0.381	4.0	-9999.0	0.0	4.0
SHH Np/Cholesterol	-0.048	0.097	-9999.0	0.0	-0.29	16.0	16.0
PTCH1	-0.02	0.151	0.308	3.0	-0.323	20.0	23.0
HHIP	-0.009	0.144	0.381	2.0	-0.512	8.0	10.0