Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.097 0.251 -9999.0 0.0 -0.634 15.0 15.0 MAP3K8 0.004 0.086 -9999.0 0.0 -0.518 3.0 3.0 FOS -0.076 0.206 -9999.0 0.0 -0.535 15.0 15.0 PRKCA -0.003 0.098 -9999.0 0.0 -0.513 4.0 4.0 PTPN7 0.013 0.071 0.366 2.0 -0.518 1.0 3.0 HRAS 0.026 0.033 0.378 1.0 -9999.0 0.0 1.0 PRKCB -0.039 0.162 -9999.0 0.0 -0.515 12.0 12.0 NRAS 0.015 0.07 -9999.0 0.0 -0.514 2.0 2.0 RAS family/GTP 0.026 0.056 -9999.0 0.0 -0.303 2.0 2.0 MAPK3 -0.041 0.167 -9999.0 0.0 -0.631 7.0 7.0 MAP2K1 -0.079 0.18 -9999.0 0.0 -0.446 20.0 20.0 ELK1 0.012 0.025 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.063 0.154 -9999.0 0.0 -0.415 17.0 17.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 24.0 24.0 MAPK1 -0.055 0.193 -9999.0 0.0 -0.657 9.0 9.0 RAF1 -0.065 0.16 -9999.0 0.0 -0.421 18.0 18.0 KRAS 0.023 0.007 -9999.0 0.0 -9999.0 0.0 0.0