		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q
1p gain	56 (12%)	396	0.00044663	0.311	0.10605	1	1	1	0.85872	1	0.97618	1	0.97271	1	0.43234	1	0.78475	1	0.64461	1	0.61452	1
1q gain	101 (22%)	351	2.8207e-07	0.000216	1.9734e-07	0.000151	0.28948	1	0.65283	1	0.00041434	0.29	0.0010179	0.697	0.00019092	0.137	0.2652	1	0.00032145	0.226	0.002152	1
2p gain	79 (17%)	373	1.3158e-08	1.02e-05	2.1025e-10	1.65e-07	0.081676	1	0.70791	1	0.019781	1	0.027812	1	0.22503	1	0.057359	1	0.1311	1	3.2446e-05	0.0239
2q gain	62 (14%)	390	1.1267e-07	8.66e-05	2.5852e-09	2.02e-06	0.53354	1	0.89847	1	0.084112	1	0.11634	1	0.6478	1	0.0864	1	0.15556	1	0.016023	1
3p gain	68 (15%)	384	0.16594	1	0.00025243	0.179	0.11191	1	0.050456	1	0.0026654	1	0.0059259	1	0.002781	1	0.09734	1	0.19188	1	0.68537	1
3q gain	218 (48%)	234	0.00028029	0.198	4.5273e-05	0.0332	0.68232	1	0.62813	1	0.00042227	0.295	0.0038193	1	0.0031199	1	0.14604	1	0.10104	1	0.58212	1
4p gain	32 (7%)	420	0.031854	1	0.00022762	0.162	0.5761	1	0.8238	1	0.25326	1	0.37284	1	0.058904	1	0.12337	1	0.31002	1	0.26292	1
4q gain	28 (6%)	424	0.43191	1	0.03581	1	1	1	0.89197	1	0.61466	1	0.71122	1	0.82191	1	1	1	0.7654	1	0.37832	1
5p gain	166 (37%)	286	8.2378e-09	6.42e-06	0.001472	0.995	0.93582	1	0.63953	1	0.065449	1	0.76072	1	0.2813	1	1	1	0.22415	1	0.94046	1
5q gain	59 (13%)	393	0.010424	1	0.49842	1	0.5078	1	0.6729	1	0.77839	1	0.51919	1	0.49182	1	0.23475	1	0.90616	1	0.51982	1
6p gain	67 (15%)	385	0.00021757	0.155	0.014467	1	0.49218	1	0.56312	1	0.94929	1	0.67426	1	0.87973	1	0.10326	1	0.62479	1	0.46621	1
6q gain	54 (12%)	398	0.0013364	0.906	0.021199	1	0.19677	1	0.12706	1	0.10141	1	0.10686	1	0.16073	1	0.38867	1	0.25078	1	0.53885	1
7p gain	162 (36%)	290	6.5773e-10	5.16e-07	3.856e-08	2.97e-05	0.62432	1	0.52004	1	0.70081	1	0.66478	1	0.13601	1	0.13791	1	0.37819	1	0.065907	1
7q gain	111 (25%)	341	4.3211e-07	0.00033	8.3223e-09	6.47e-06	0.17555	1	0.91277	1	0.1343	1	0.10656	1	0.0034541	1	0.73947	1	0.17979	1	0.0010754	0.736
8p gain	129 (29%)	323	0.25014	1	0.016939	1	0.42456	1	0.62821	1	0.38483	1	0.11551	1	0.40388	1	0.62004	1	0.54353	1	0.65304	1
8q gain	272 (60%)	180	0.00443	1	0.00040867	0.287	0.093453	1	0.68169	1	0.14861	1	0.10493	1	0.16484	1	0.033937	1	0.38633	1	0.096899	1
9p gain	89 (20%)	363	5.1347e-19	4.1e-16	0.00018941	0.136	0.3542	1	0.021411	1	0.037386	1	0.011139	1	0.023157	1	0.64627	1	0.0050127	1	0.41111	1
9q gain	120 (27%)	332	1.9703e-16	1.57e-13	0.044914	1	0.129	1	0.10276	1	0.52045	1	0.088943	1	0.69113	1	0.45596	1	0.17156	1	0.33175	1
10p gain	34 (8%)	418	0.035615	1	7.7612e-06	0.00581	0.57872	1	0.5291	1	0.14371	1	0.030928	1	0.12953	1	0.18916	1	0.27897	1	0.049341	1
10q gain	32 (7%)	420	0.024276	1	0.42156	1	0.097263	1	0.34104	1	0.48206	1	0.31743	1	0.52904	1	0.21011	1	0.42764	1	0.063511	1
11p gain	56 (12%)	396	0.03296	1	0.00041285	0.289	0.83938	1	0.66498	1	0.37619	1	0.052562	1	0.45241	1	0.52825	1	0.0040592	1	0.83527	1
11q gain	60 (13%)	392	0.13057	1	0.0017515	1	0.42767	1	0.76071	1	0.28907	1	0.05451	1	0.7173	1	0.59377	1	0.16596	1	0.6192	1
12p gain	125 (28%)	327	1.6525e-08	1.28e-05	5.4853e-07	0.000417	0.016096	1	0.31798	1	0.0027874	1	0.0024668	1	0.025608	1	0.33308	1	0.034116	1	0.0024933	1
12q gain	76 (17%)	376	0.00012543	0.0904	0.0011179	0.761	0.079149	1	0.14928	1	0.025864	1	0.077966	1	0.50943	1	0.92574	1	0.067434	1	0.061148	1
13q gain	51 (11%)	401	0.00080941	0.557	0.0050125	1	0.58842	1	0.50238	1	0.0028428	1	0.010658	1	0.13445	1	0.046919	1	0.046194	1	0.61263	1
14q gain	131 (29%)	321	5.5222e-07	0.00042	5.9434e-06	0.00446	0.21676	1	0.47922	1	0.090496	1	0.40622	1	0.089935	1	0.0016855	1	0.11447	1	0.004054	1
15q gain	66 (15%)	386	0.0061807	1	0.071254	1	0.38116	1	0.85143	1	0.24246	1	0.51206	1	0.49772	1	0.6013	1	0.19727	1	0.53334	1
16p gain	93 (21%)	359	2.0944e-05	0.0155	4.4576e-07	0.00034	0.32424	1	0.81329	1	0.47224	1	0.98301	1	0.51185	1	0.41779	1	0.60836	1	0.27191	1
16q gain	94 (21%)	358	1.7453e-05	0.013	8.6949e-05	0.063	0.49887	1	0.82604	1	0.19018	1	0.17873	1	0.35632	1	0.060298	1	0.4951	1	0.25794	1
17p gain	59 (13%)	393	4.4101e-06	0.00332	5.6607e-05	0.0413	0.59659	1	0.31058	1	0.0034836	1	0.04646	1	0.034479	1	0.031794	1	0.70101	1	0.14635	1
17q gain	76 (17%)	376	2.2366e-07	0.000171	0.00019358	0.138	0.52963	1	0.60394	1	0.068972	1	0.074254	1	0.11371	1	0.46164	1	0.24949	1	0.016325	1
18p gain	105 (23%)	347	2.806e-08	2.17e-05	2.7033e-06	0.00205	0.33276	1	0.76945	1	0.062669	1	0.0033151	1	0.67798	1	0.93651	1	0.0022883	1	0.037409	1
18q gain	43 (10%)	409	0.54693	1	7.7286e-05	0.0561	0.016803	1	0.40811	1	0.00071677	0.495	0.0032171	1	0.0010819	0.739	0.35333	1	0.00010714	0.0775	0.19365	1
19p gain	40 (9%)	412	0.092806	1	1.8056e-05	0.0134	0.089235	1	0.068385	1	0.082883	1	0.028113	1	0.073613	1	0.13827	1	0.31531	1	0.31419	1
19q gain	57 (13%)	395	0.26465	1	0.0003383	0.238	0.90588	1	0.3381	1	0.06058	1	0.012875	1	0.04705	1	0.1907	1	0.37682	1	0.18202	1
20p gain	165 (37%)	287	0.0067896	1	3.4757e-05	0.0256	0.89294	1	0.26723	1	0.0060172	1	0.031671	1	0.068313	1	0.011923	1	0.52799	1	0.024707	1
20q gain	175 (39%)	277	8.7507e-05	0.0634	3.192e-06	0.00241	0.87447	1	0.82011	1	0.0015233	1	0.0032825	1	0.079139	1	0.0076475	1	0.11937	1	0.027643	1
21q gain	29 (6%)	423	0.073826	1	0.027366	1	0.015127	1	0.76785	1	0.10355	1	0.12105	1	0.21748	1	0.87295	1	0.0077819	1	0.30392	1
22q gain	95 (21%)	357	0.00019544	0.14	4.6256e-11	3.65e-08	0.1526	1	0.37624	1	0.031351	1	0.075888	1	0.013885	1	0.50134	1	2.1254e-05	0.0157	7.4059e-05	0.0538
xq gain	72 (16%)	380	4.0373e-05	0.0297	0.004261	1	0.25074	1	0.75124	1	0.14235	1	0.032626	1	0.24176	1	0.31678	1	0.6721	1	0.90451	1
1p loss	47 (10%)	405	0.00022179	0.158	9.8472e-09	7.65e-06	0.064982	1	0.53815	1	0.0044235	1	0.028283	1	0.20491	1	0.68458	1	0.57501	1	0.0013182	0.895
1q loss	33 (7%)	419	0.32423	1	0.11161	1	0.77998	1	0.69635	1	0.25468	1	0.19275	1	0.11778	1	0.10959	1	0.04461	1	0.63172	1
2p loss	30 (7%)	422	0.15249	1	0.014138	1	0.15909	1	0.15253	1	0.13387	1	0.41002	1	0.08197	1	0.73606	1	0.28438	1	0.5684	1
2q loss	40 (9%)	412	0.31244	1	0.028028	1	0.83585	1	0.17175	1	0.7769	1	0.52897	1	0.32402	1	0.77578	1	0.43873	1	0.84717	1
3p loss	262 (58%)	190	5.8737e-24	4.69e-21	1.3589e-15	1.08e-12	0.88382	1	0.088644	1	0.033525	1	0.20764	1	0.092905	1	0.11735	1	0.34463	1	0.0029085	1
3q loss	57 (13%)	395	0.012398	1	0.38238	1	0.39331	1	1	1	0.61055	1	0.84745	1	0.54983	1	0.71483	1	0.3531	1	0.46677	1
4p loss	167 (37%)	285	2.2098e-14	1.75e-11	3.0048e-12	2.38e-09	0.039159	1	0.59242	1	0.00085236	0.586	2.8825e-05	0.0213	0.019564	1	0.8852	1	0.021306	1	4.2861e-06	0.00323
4q loss	133 (29%)	319	6.9378e-11	5.46e-08	3.2831e-08	2.53e-05	0.55343	1	0.43352	1	0.017373	1	0.0050779	1	0.012371	1	0.65508	1	0.17852	1	0.006065	1
5p loss	41 (9%)	411	0.0003012	0.213	0.0003105	0.219	0.37521	1	0.59107	1	0.67958	1	0.27746	1	0.57907	1	0.80241	1	0.072721	1	0.46666	1
5q loss	138 (31%)	314	7.7813e-15	6.18e-12	4.1537e-15	3.3e-12	0.2053	1	0.1454	1	0.22246	1	0.00076073	0.525	0.73259	1	0.14518	1	0.33364	1	0.066598	1
6p loss	59 (13%)	393	0.0014161	0.959	0.0038633	1	0.028232	1	0.48061	1	0.17112	1	0.3719	1	0.3483	1	0.95723	1	0.75021	1	0.13255	1
6q loss	56 (12%)	396	0.049747	1	0.0098208	1	0.13387	1	0.2732	1	0.72401	1	0.7229	1	0.62198	1	0.54599	1	0.63948	1	0.74219	1
7p loss	24 (5%)	428	0.07288	1	0.1191	1	0.010206	1	0.20746	1	0.9339	1	0.28978	1	0.28546	1	0.66046	1	0.088831	1	0.29795	1
7q loss	39 (9%)	413	0.39849	1	0.13859	1	0.52519	1	0.27131	1	0.27474	1	0.4977	1	0.12258	1	0.13465	1	0.68663	1	0.20187	1
8p loss	166 (37%)	286	1.842e-05	0.0137	0.00012027	0.0868	0.34785	1	0.31144	1	0.16286	1	0.019185	1	0.28085	1	0.015756	1	0.10683	1	0.0031137	1
8q loss	25 (6%)	427	0.096803	1	0.58844	1	0.67816	1	0.64803	1	1	1	1	1	0.74918	1	0.76247	1	0.61684	1	0.30166	1
9p loss	152 (34%)	300	4.8751e-29	3.9e-26	3.3981e-14	2.69e-11	0.69014	1	0.13604	1	0.38486	1	0.17745	1	0.06019	1	0.50681	1	0.073952	1	0.00054927	0.381
9q loss	70 (15%)	382	1.7474e-10	1.37e-07	8.9631e-06	0.0067	0.97278	1	0.85143	1	0.50219	1	0.394	1	0.87747	1	0.0045008	1	0.30851	1	0.07156	1
10p loss	134 (30%)	318	2.2762e-06	0.00173	0.0024361	1	0.31622	1	0.09801	1	0.45813	1	0.29305	1	0.17322	1	0.27017	1	0.6304	1	0.093847	1
10q loss	91 (20%)	361	1.6411e-05	0.0122	0.00080443	0.554	0.20753	1	0.33021	1	0.0809	1	0.018767	1	0.11129	1	0.77882	1	0.0057858	1	0.45923	1
11p loss	116 (26%)	336	7.9219e-08	6.1e-05	0.00049359	0.344	0.43648	1	0.91683	1	0.002234	1	0.013657	1	0.013848	1	0.73349	1	0.063199	1	0.092994	1
11q loss	139 (31%)	313	0.00014665	0.105	5.4018e-05	0.0395	0.12557	1	0.40883	1	0.0037101	1	0.030409	1	0.56144	1	0.56263	1	0.31171	1	0.9059	1
12p loss	29 (6%)	423	0.5886	1	0.036426	1	0.6461	1	0.60528	1	0.74883	1	1	1	0.28327	1	0.59959	1	0.29971	1	0.094963	1
12q loss	25 (6%)	427	0.067371	1	0.010045	1	0.87131	1	0.26688	1	0.49846	1	0.75985	1	0.54639	1	0.33776	1	0.14012	1	0.23208	1
13q loss	145 (32%)	307	7.6036e-06	0.0057	2.6777e-07	0.000205	0.45409	1	0.90718	1	0.0016309	1	6.5843e-05	0.0479	0.010232	1	0.93111	1	0.010496	1	0.024838	1
14q loss	44 (10%)	408	0.13344	1	0.014943	1	0.037227	1	0.41525	1	0.0085432	1	0.098682	1	0.069106	1	0.36343	1	0.0023553	1	0.0092726	1
15q loss	83 (18%)	369	1.4224e-06	0.00108	0.16799	1	0.62524	1	0.41349	1	0.036832	1	0.10429	1	0.22338	1	0.25669	1	0.1773	1	0.32432	1
16p loss	53 (12%)	399	0.0019326	1	0.0030037	1	0.98718	1	0.65234	1	0.03768	1	0.033391	1	0.75982	1	0.2123	1	0.25073	1	0.42861	1
16q loss	68 (15%)	384	0.56064	1	2.5121e-09	1.96e-06	0.47868	1	0.078006	1	2.6874e-08	2.08e-05	2.3166e-09	1.81e-06	0.0076962	1	0.066069	1	1.0706e-05	0.008	0.060492	1
17p loss	96 (21%)	356	2.0479e-05	0.0152	0.00019077	0.137	0.39291	1	0.27806	1	0.50486	1	0.136	1	0.60778	1	0.73755	1	0.1693	1	0.66488	1
17q loss	30 (7%)	422	0.041678	1	0.43706	1	0.90272	1	0.0047845	1	0.63688	1	0.49278	1	0.78215	1	0.59959	1	0.57182	1	0.83042	1
18p loss	88 (19%)	364	0.0061461	1	0.00089852	0.616	0.64744	1	0.27976	1	0.79562	1	0.6478	1	0.36769	1	0.62774	1	0.24036	1	0.75101	1
18q loss	185 (41%)	267	6.802e-11	5.36e-08	9.2184e-12	7.28e-09	0.2812	1	0.012915	1	0.0027966	1	0.00020595	0.147	0.041592	1	0.002963	1	0.041766	1	0.1043	1
19p loss	87 (19%)	365	0.002525	1	0.00023832	0.169	0.70291	1	0.2041	1	0.016975	1	0.072577	1	0.35977	1	0.038318	1	0.046504	1	0.28695	1
19q loss	77 (17%)	375	5.5971e-05	0.0409	4.3655e-05	0.032	0.13361	1	0.44159	1	0.2186	1	0.43976	1	0.29417	1	0.23481	1	0.93607	1	0.58877	1
20p loss	44 (10%)	408	5.2659e-06	0.00396	0.0011161	0.761	0.48326	1	0.16982	1	0.20143	1	0.36415	1	0.16424	1	0.12521	1	0.51914	1	0.45767	1
20q loss	28 (6%)	424	0.0042131	1	0.0052306	1	0.2116	1	0.057998	1	0.024409	1	0.0012378	0.842	0.012154	1	0.14436	1	0.01481	1	0.21126	1
21q loss	162 (36%)	290	2.6724e-09	2.08e-06	1.5569e-07	0.00012	0.57123	1	0.5117	1	0.30448	1	0.41654	1	0.77216	1	0.40105	1	0.27844	1	0.037846	1
22q loss	67 (15%)	385	0.072678	1	0.00044035	0.307	0.81139	1	0.45891	1	0.00013875	0.0999	0.012588	1	0.00050965	0.354	0.17218	1	0.00052266	0.363	0.094463	1
xq loss	71 (16%)	381	0.00062619	0.433	2.7568e-06	0.00208	0.18051	1	0.072536	1	0.0091234	1	0.01951	1	3.0886e-05	0.0228	0.23002	1	0.023157	1	6.0958e-05	0.0444
