		Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	166 (29%)	403	0.10528	1	0.17636	1	0.11996	1	0.24892	1	0.0024112	1	0.15457	1	0.087496	1	0.61901	1	0.6009	1	0.79657	1	0.21517	1	0.88474	1	0.15483	1	0.2312	1
1q gain	218 (38%)	351	0.77551	1	0.34752	1	0.70491	1	0.14668	1	9.7777e-08	0.000108	0.0057376	1	0.45568	1	0.9924	1	0.43565	1	0.5668	1	0.20539	1	0.34981	1	0.1132	1	0.17882	1
2p gain	178 (31%)	391	1.4765e-06	0.00163	1.9591e-06	0.00216	0.81085	1	0.00010085	0.109	2.3559e-11	2.62e-08	1.3229e-07	0.000147	0.03756	1	0.28498	1	0.00012718	0.137	0.007203	1	0.81214	1	0.26356	1	0.79707	1	0.29879	1
2q gain	150 (26%)	419	0.0004172	0.446	1.8237e-05	0.0199	0.97858	1	0.0032521	1	4.4206e-09	4.91e-06	0.00014332	0.154	0.097911	1	0.71579	1	0.003696	1	0.018846	1	0.60612	1	0.86885	1	0.10762	1	0.13141	1
3p gain	154 (27%)	415	0.33746	1	0.65768	1	0.043112	1	0.55432	1	0.013003	1	0.83882	1	1	1	0.89584	1	0.77177	1	0.43611	1	0.91572	1	0.4058	1	0.89978	1	0.1345	1
3q gain	268 (47%)	301	0.97127	1	0.77982	1	0.25149	1	0.59989	1	3.5328e-06	0.00388	0.018835	1	0.58504	1	0.33895	1	0.69826	1	0.64297	1	0.1826	1	0.14938	1	0.11876	1	0.39988	1
4p gain	57 (10%)	512	0.24264	1	0.24592	1	0.005163	1	0.3189	1	0.12822	1	0.11685	1	0.47226	1	0.18222	1	0.59501	1	0.4388	1	0.3225	1	0.061869	1	0.57353	1	0.089674	1
4q gain	32 (6%)	537	0.65659	1	0.76672	1	0.1549	1	0.57678	1	0.0351	1	0.017561	1	0.27447	1	0.60671	1	0.77389	1	0.514	1	0.37551	1	0.0067237	1	0.48214	1	0.40421	1
5p gain	196 (34%)	373	0.58594	1	0.98637	1	0.8542	1	0.66316	1	6.7944e-05	0.0737	0.19367	1	0.48289	1	0.24558	1	0.12303	1	0.44321	1	0.22965	1	0.55046	1	0.62054	1	0.052513	1
5q gain	60 (11%)	509	0.082902	1	0.22247	1	0.79911	1	0.5021	1	0.49881	1	0.50703	1	0.42353	1	0.24175	1	0.73505	1	0.48959	1	0.498	1	0.60269	1	0.64553	1	0.49481	1
6p gain	166 (29%)	403	0.50973	1	0.13657	1	0.897	1	0.087145	1	1.3819e-06	0.00152	8.6125e-05	0.0933	0.86043	1	0.14365	1	0.15779	1	0.84229	1	0.35016	1	0.59014	1	0.44142	1	0.22026	1
6q gain	96 (17%)	473	0.64763	1	0.097345	1	0.81906	1	0.1739	1	3.0644e-07	0.000339	1.3515e-05	0.0148	0.80172	1	0.67745	1	0.004992	1	0.26062	1	0.19489	1	0.25312	1	0.46672	1	0.070471	1
7p gain	181 (32%)	388	0.62288	1	0.86102	1	0.071605	1	0.15583	1	7.5679e-07	0.000835	0.00010972	0.118	0.50501	1	0.37976	1	0.56131	1	0.47049	1	0.92132	1	0.30252	1	0.36602	1	0.62015	1
7q gain	198 (35%)	371	0.64568	1	0.26683	1	0.29732	1	0.55578	1	1.6935e-05	0.0185	0.0014507	1	0.44822	1	0.19881	1	0.9195	1	0.69065	1	0.14814	1	0.7475	1	0.05431	1	0.73861	1
8p gain	117 (21%)	452	0.068549	1	0.012823	1	0.29801	1	0.019304	1	0.71429	1	0.79609	1	0.13126	1	0.17504	1	0.6099	1	0.65633	1	0.10635	1	0.12576	1	0.17526	1	0.063857	1
8q gain	238 (42%)	331	0.020567	1	0.0066496	1	0.060981	1	0.11889	1	0.1798	1	0.4461	1	0.31683	1	0.52606	1	0.030002	1	0.20355	1	0.46125	1	0.5964	1	0.28893	1	0.64094	1
9p gain	91 (16%)	478	0.107	1	0.83224	1	0.23917	1	0.77338	1	0.018828	1	0.0083242	1	0.39565	1	0.92198	1	0.6793	1	0.16424	1	0.18614	1	0.32282	1	0.4881	1	0.15788	1
9q gain	45 (8%)	524	0.24773	1	0.21604	1	0.094325	1	0.64075	1	0.18148	1	0.22196	1	0.56493	1	0.22644	1	0.47142	1	0.020304	1	0.48657	1	0.70347	1	0.43859	1	0.75222	1
10p gain	184 (32%)	385	0.0044155	1	0.062179	1	0.67059	1	0.029914	1	1.4469e-10	1.61e-07	0.00017352	0.186	0.97447	1	0.24079	1	0.011248	1	0.46726	1	0.54294	1	0.62505	1	0.50668	1	0.22119	1
10q gain	108 (19%)	461	0.0037944	1	0.033936	1	0.23803	1	0.0092155	1	0.0012588	1	0.090941	1	0.75893	1	0.63065	1	0.10754	1	0.44657	1	0.73603	1	0.68976	1	0.94895	1	0.36092	1
11p gain	76 (13%)	493	0.68443	1	0.30279	1	0.62396	1	0.84927	1	0.34408	1	0.013986	1	0.027628	1	0.033835	1	0.060162	1	0.24072	1	0.55279	1	0.65203	1	0.866	1	1	1
11q gain	114 (20%)	455	0.44578	1	0.38667	1	0.86334	1	0.086197	1	0.04062	1	0.0016085	1	0.16382	1	0.016596	1	0.28942	1	0.079992	1	0.52068	1	0.79919	1	0.8425	1	0.66935	1
12p gain	250 (44%)	319	4.3983e-05	0.0478	8.8845e-05	0.0961	0.7444	1	0.00072617	0.771	1.0548e-13	1.18e-10	1.8378e-07	0.000203	0.29915	1	0.56455	1	0.00038275	0.41	0.0042574	1	0.18279	1	0.30651	1	0.29706	1	0.13672	1
12q gain	174 (31%)	395	0.006272	1	5.087e-05	0.0552	0.64404	1	0.33933	1	2.0379e-12	2.28e-09	5.4901e-06	0.00602	0.025795	1	0.26303	1	0.0018935	1	0.0041541	1	0.10209	1	0.11017	1	0.57134	1	0.12152	1
13q gain	60 (11%)	509	0.0064065	1	0.035226	1	0.56834	1	3.2104e-05	0.035	0.00012537	0.135	4.8999e-06	0.00538	0.57693	1	0.45309	1	0.24551	1	0.82556	1	0.18795	1	1	1	0.95449	1	0.91051	1
14q gain	58 (10%)	511	0.1466	1	0.52484	1	0.40119	1	0.28666	1	0.8008	1	0.73348	1	0.32853	1	0.12541	1	0.49591	1	0.32366	1	0.6377	1	0.68132	1	0.5646	1	0.42618	1
15q gain	39 (7%)	530	0.84289	1	0.57206	1	0.09418	1	0.28382	1	0.40126	1	0.5696	1	0.11049	1	0.23227	1	0.75344	1	0.53068	1	0.29795	1	0.36167	1	0.51782	1	0.15758	1
16p gain	58 (10%)	511	0.0026485	1	0.0027881	1	0.40119	1	0.59947	1	0.085011	1	0.018167	1	0.34783	1	0.014196	1	0.63718	1	0.66485	1	0.12835	1	0.14192	1	0.1948	1	0.044426	1
16q gain	30 (5%)	539	0.00082801	0.878	0.013346	1	0.16886	1	0.47814	1	0.68676	1	0.0036905	1	0.43296	1	0.23208	1	1	1	0.15102	1	0.00092452	0.977	0.034471	1	0.0027153	1	0.0065006	1
17p gain	22 (4%)	547	0.42343	1	0.55557	1	0.064971	1	0.45537	1	0.22445	1	0.24144	1	0.48347	1	0.51086	1	0.20321	1	0.70474	1	0.17366	1	0.47436	1	0.41234	1	0.23751	1
17q gain	49 (9%)	520	0.33505	1	0.16493	1	0.85431	1	0.69224	1	0.77411	1	0.29692	1	0.46168	1	0.43713	1	0.90011	1	0.90482	1	0.77063	1	0.83611	1	0.44311	1	0.82658	1
18p gain	117 (21%)	452	0.23058	1	0.12241	1	0.92065	1	0.44075	1	0.0047316	1	0.00047208	0.503	0.023059	1	0.10714	1	0.77878	1	0.7773	1	0.35531	1	0.93841	1	0.34241	1	0.78256	1
18q gain	71 (12%)	498	0.64541	1	0.47133	1	0.28554	1	0.37468	1	0.053789	1	0.037989	1	0.53171	1	0.35912	1	0.48182	1	0.13268	1	0.11232	1	0.37894	1	0.053969	1	0.45851	1
19p gain	167 (29%)	402	0.067639	1	0.18066	1	0.56607	1	0.73872	1	4.183e-05	0.0455	0.029489	1	0.05556	1	0.63249	1	0.23231	1	0.48433	1	0.37588	1	0.19979	1	0.54525	1	0.8092	1
19q gain	160 (28%)	409	0.20752	1	0.45644	1	0.86108	1	0.47432	1	4.5444e-06	0.00499	0.09891	1	0.48455	1	0.89644	1	0.20753	1	0.25728	1	0.26863	1	0.1521	1	0.44288	1	0.90296	1
20p gain	282 (50%)	287	0.0013803	1	0.0061415	1	0.71849	1	0.0006145	0.654	1.004e-11	1.12e-08	2.7299e-08	3.03e-05	0.33702	1	0.22023	1	0.0027322	1	0.33769	1	0.22409	1	0.91775	1	0.60183	1	0.70572	1
20q gain	320 (56%)	249	8.7646e-06	0.0096	0.0014567	1	0.66994	1	0.00020432	0.219	4.5014e-15	5.04e-12	2.582e-10	2.87e-07	0.65944	1	0.023174	1	0.0089567	1	0.84301	1	0.25894	1	0.92368	1	0.66757	1	0.48304	1
21q gain	109 (19%)	460	0.29251	1	0.22099	1	0.96646	1	0.96431	1	0.0011725	1	0.016759	1	0.44308	1	0.52263	1	0.32724	1	0.090223	1	0.023863	1	0.50224	1	0.10211	1	0.25802	1
22q gain	25 (4%)	544	0.52571	1	0.82466	1	0.88393	1	0.76304	1	0.12956	1	0.21572	1	0.36989	1	0.80039	1	0.4651	1	0.69133	1	0.061305	1	0.094762	1	0.087296	1	0.11885	1
xq gain	104 (18%)	465	0.55266	1	0.50424	1	0.82407	1	0.71544	1	0.0024111	1	0.87835	1	0.26476	1	0.37353	1	0.77664	1	0.8806	1	0.54118	1	0.87561	1	0.46411	1	0.29177	1
1p loss	61 (11%)	508	0.028793	1	0.015419	1	0.59423	1	0.13984	1	0.45744	1	0.25904	1	0.035674	1	0.34085	1	0.58478	1	0.48959	1	0.44444	1	0.63628	1	0.042262	1	0.36141	1
1q loss	39 (7%)	530	0.097879	1	0.010473	1	0.11897	1	0.68867	1	0.95866	1	0.31933	1	0.32606	1	0.79304	1	0.46838	1	0.20166	1	0.95033	1	1	1	0.25434	1	0.87596	1
2p loss	53 (9%)	516	0.89932	1	0.83327	1	0.8145	1	0.72354	1	0.51845	1	0.71906	1	0.47039	1	0.52471	1	0.61173	1	0.48383	1	0.71786	1	0.1172	1	0.59626	1	0.90649	1
2q loss	59 (10%)	510	0.96451	1	0.62892	1	0.76021	1	0.1015	1	0.751	1	0.62986	1	0.79636	1	0.8863	1	0.6324	1	0.33023	1	0.67004	1	0.23233	1	0.64753	1	0.41715	1
3p loss	95 (17%)	474	0.04064	1	0.026826	1	0.88598	1	0.020234	1	0.00010564	0.114	0.0026991	1	0.62965	1	0.29273	1	0.059518	1	0.85678	1	0.12706	1	0.94316	1	0.90923	1	0.0019353	1
3q loss	41 (7%)	528	0.021082	1	0.012289	1	0.29701	1	0.13472	1	0.0059998	1	0.0013917	1	1	1	0.61425	1	0.23446	1	0.7168	1	0.23523	1	0.10173	1	0.27879	1	0.0070587	1
4p loss	312 (55%)	257	0.46636	1	0.3045	1	0.27673	1	0.02725	1	0.004066	1	0.60195	1	0.14483	1	0.29753	1	0.60767	1	0.86109	1	0.068707	1	0.0076303	1	0.052535	1	0.026215	1
4q loss	355 (62%)	214	0.28214	1	0.26416	1	0.4457	1	0.035897	1	0.0013738	1	0.66821	1	0.10278	1	0.083683	1	0.35896	1	0.17255	1	0.13547	1	0.00040804	0.436	0.027152	1	0.040186	1
5p loss	129 (23%)	440	0.094204	1	0.087747	1	0.48875	1	0.0045296	1	0.020905	1	0.0067517	1	0.10793	1	0.67665	1	0.00013705	0.147	0.50963	1	0.65375	1	0.52384	1	0.38358	1	0.051191	1
5q loss	218 (38%)	351	0.00052984	0.564	0.029978	1	0.7659	1	0.0022249	1	0.00088549	0.937	1.4135e-07	0.000156	0.045211	1	0.20417	1	0.0010143	1	0.64664	1	0.53968	1	0.60045	1	0.29725	1	0.43915	1
6p loss	164 (29%)	405	0.96807	1	0.4679	1	0.37108	1	0.72543	1	0.060357	1	0.11343	1	0.70234	1	0.59656	1	0.40862	1	0.52916	1	0.47581	1	0.67323	1	0.32241	1	0.63509	1
6q loss	239 (42%)	330	0.95857	1	0.41209	1	0.43946	1	0.53572	1	0.017142	1	0.071043	1	0.62303	1	0.39432	1	0.020212	1	0.03141	1	0.79164	1	0.94252	1	0.91084	1	0.44504	1
7p loss	118 (21%)	451	0.98115	1	0.60176	1	0.43039	1	0.3865	1	0.30034	1	0.14155	1	0.59237	1	0.79618	1	0.63185	1	0.026221	1	0.52733	1	0.40991	1	0.76645	1	0.4158	1
7q loss	81 (14%)	488	0.34319	1	0.40813	1	0.34207	1	0.39225	1	0.91736	1	0.10861	1	0.81506	1	0.22255	1	0.47682	1	0.16252	1	0.12476	1	1	1	0.50175	1	0.90826	1
8p loss	271 (48%)	298	0.74273	1	0.87676	1	0.24032	1	0.73604	1	0.0035872	1	0.10885	1	0.12005	1	0.16617	1	0.47569	1	0.84223	1	0.68625	1	0.026757	1	0.80207	1	0.26881	1
8q loss	88 (15%)	481	0.0074995	1	0.058058	1	0.53295	1	0.085812	1	0.0019115	1	0.034658	1	0.02209	1	0.21308	1	0.00087254	0.924	0.03711	1	0.64629	1	0.36966	1	0.76451	1	0.50103	1
9p loss	255 (45%)	314	0.0031873	1	0.034646	1	0.51157	1	0.10426	1	0.0083444	1	0.070079	1	0.78714	1	0.50513	1	0.8825	1	0.35347	1	0.053138	1	0.37129	1	0.062501	1	0.2861	1
9q loss	280 (49%)	289	0.0051497	1	0.03755	1	0.22212	1	0.011252	1	2.1934e-12	2.45e-09	0.003672	1	0.58504	1	1	1	0.0044382	1	0.40694	1	0.18314	1	0.17849	1	0.25129	1	0.092881	1
10p loss	94 (17%)	475	0.29704	1	0.74957	1	0.25767	1	0.16197	1	0.56627	1	0.27632	1	0.58937	1	0.12157	1	0.79931	1	0.26597	1	0.43351	1	0.56276	1	0.40462	1	0.49536	1
10q loss	122 (21%)	447	0.96359	1	0.4578	1	0.0040881	1	0.18708	1	0.081	1	0.0011542	1	0.35485	1	0.026291	1	0.6795	1	0.19123	1	0.76163	1	0.77102	1	0.84985	1	0.76522	1
11p loss	193 (34%)	376	0.23663	1	0.029225	1	0.54164	1	0.57579	1	0.12351	1	0.03523	1	0.10013	1	0.56323	1	0.038901	1	0.10271	1	0.47586	1	0.092545	1	0.077671	1	0.12088	1
11q loss	144 (25%)	425	0.36054	1	0.31976	1	0.17713	1	0.62354	1	0.015705	1	0.093636	1	0.4639	1	0.64312	1	0.26324	1	0.2527	1	0.51069	1	0.14611	1	0.10213	1	0.043754	1
12p loss	78 (14%)	491	0.0028241	1	0.02393	1	0.53566	1	0.14754	1	0.0029046	1	0.25471	1	0.77121	1	0.23359	1	0.32706	1	0.33665	1	0.0097071	1	0.0043462	1	0.0023028	1	0.0081847	1
12q loss	104 (18%)	465	0.067687	1	0.0056592	1	0.75993	1	0.62344	1	0.058932	1	0.2026	1	0.26377	1	0.65623	1	0.23772	1	0.017318	1	0.045881	1	0.020394	1	0.10819	1	0.030974	1
13q loss	303 (53%)	266	0.034305	1	0.04252	1	0.78714	1	0.18203	1	0.0060543	1	1.3607e-05	0.0149	0.010015	1	0.018215	1	0.47237	1	0.97754	1	0.25284	1	0.8251	1	0.093821	1	0.94798	1
14q loss	208 (37%)	361	0.20994	1	0.10123	1	0.97365	1	0.90849	1	1.3452e-05	0.0147	0.0032295	1	0.97094	1	0.81193	1	0.0038262	1	0.14844	1	0.79809	1	0.7972	1	0.96999	1	0.44965	1
15q loss	276 (49%)	293	0.00042977	0.459	0.0011826	1	0.00010449	0.113	0.00063422	0.674	4.3069e-12	4.81e-09	3.9783e-07	0.000439	0.37104	1	0.4129	1	0.065618	1	0.83912	1	0.0068962	1	0.28771	1	0.030015	1	0.0010229	1
16p loss	325 (57%)	244	0.3192	1	0.56528	1	0.037586	1	0.50347	1	0.12281	1	0.095659	1	0.79956	1	0.52263	1	0.052791	1	0.43327	1	0.080246	1	0.11591	1	0.11344	1	0.09828	1
16q loss	404 (71%)	165	0.56468	1	0.40566	1	0.0034451	1	0.30189	1	0.0020545	1	0.062689	1	0.94758	1	0.84429	1	0.20923	1	0.42664	1	0.069985	1	0.055641	1	0.048665	1	0.098261	1
17p loss	471 (83%)	98	0.2777	1	0.22124	1	0.17874	1	0.52402	1	0.46958	1	0.20772	1	0.53483	1	0.19632	1	0.10168	1	0.26822	1	0.47505	1	0.362	1	0.13438	1	0.63894	1
17q loss	376 (66%)	193	0.059135	1	0.038961	1	0.02632	1	0.57655	1	0.9677	1	0.50492	1	0.43156	1	0.20898	1	0.46955	1	0.423	1	0.056242	1	0.41801	1	7.6601e-05	0.083	0.77918	1
18p loss	234 (41%)	335	0.41764	1	0.21937	1	0.50971	1	0.086365	1	0.23635	1	0.0032276	1	0.31066	1	0.0027908	1	0.023587	1	0.50411	1	0.83951	1	0.5077	1	0.61117	1	0.79773	1
18q loss	290 (51%)	279	0.3172	1	0.082105	1	0.40087	1	0.72857	1	0.97319	1	0.10595	1	0.80555	1	0.011642	1	0.010758	1	0.2143	1	0.96878	1	0.92669	1	0.8199	1	0.72116	1
19p loss	181 (32%)	388	0.98694	1	0.90574	1	0.23103	1	0.51532	1	0.016747	1	0.032377	1	0.021526	1	0.63	1	0.74526	1	0.72551	1	0.79522	1	0.89245	1	0.86004	1	1	1
19q loss	172 (30%)	397	0.82909	1	0.39409	1	0.2855	1	0.81173	1	0.037954	1	0.1321	1	0.094134	1	0.34611	1	1	1	0.79246	1	0.36786	1	0.63493	1	0.40957	1	0.75484	1
20p loss	49 (9%)	520	0.49462	1	0.97281	1	0.22292	1	0.4459	1	0.12053	1	0.27199	1	0.09935	1	0.11412	1	0.013089	1	0.11636	1	0.00076692	0.814	0.43421	1	0.0065317	1	0.70281	1
20q loss	31 (5%)	538	0.12613	1	0.48537	1	0.035955	1	0.46923	1	0.52355	1	0.61933	1	0.053298	1	0.033567	1	0.12631	1	0.24747	1	0.13098	1	0.24558	1	0.059892	1	0.71461	1
21q loss	195 (34%)	374	0.81619	1	0.38018	1	0.38312	1	0.32734	1	0.39742	1	0.14061	1	0.641	1	0.29235	1	0.58435	1	0.5879	1	0.68053	1	0.91708	1	0.14461	1	0.86714	1
22q loss	421 (74%)	148	0.0047292	1	0.038038	1	0.036212	1	0.035171	1	0.00035022	0.375	0.0040606	1	0.069668	1	0.18748	1	0.18415	1	0.75668	1	0.040205	1	0.63073	1	0.05013	1	0.26426	1
xq loss	273 (48%)	296	0.058284	1	0.23458	1	0.28875	1	0.32203	1	0.006002	1	0.09727	1	0.37307	1	0.010222	1	0.49006	1	0.52091	1	0.78808	1	0.73052	1	0.88817	1	0.91215	1
