		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	7 (3%)	271	0.035054	1	0.092087	1	0.041065	1	0.49508	1	0.59507	1	0.13959	1	0.75391	1	1	1	0.79723	1	0.89045	1
1q gain	11 (4%)	267	0.01284	1	0.025545	1	0.022254	1	0.22387	1	0.2499	1	0.062767	1	0.72009	1	0.92201	1	1	1	0.85276	1
2p gain	4 (1%)	274	0.49836	1	0.10491	1	NA	NA	NA	NA	0.23258	1	0.17646	1	0.26455	1	0.69612	1	0.11151	1	0.69053	1
2q gain	3 (1%)	275	0.15438	1	0.28938	1	NA	NA	NA	NA	0.55946	1	0.34613	1	0.083613	1	0.10344	1	0.02647	1	0.19814	1
3p gain	19 (7%)	259	0.001312	0.778	0.069206	1	0.056137	1	0.45971	1	0.6542	1	0.059058	1	0.3932	1	1	1	0.73182	1	0.38883	1
3q gain	25 (9%)	253	7.2471e-06	0.00449	0.10623	1	0.039638	1	0.24753	1	0.25112	1	0.016274	1	0.58716	1	0.80394	1	0.77441	1	0.43278	1
4p gain	4 (1%)	274	0.49836	1	0.39143	1	NA	NA	NA	NA	0.84276	1	0.75114	1	0.62761	1	0.484	1	0.5543	1	0.38998	1
4q gain	3 (1%)	275	0.74948	1	0.50931	1	NA	NA	NA	NA	1	1	1	1	0.63213	1	0.46125	1	0.64402	1	0.77882	1
5p gain	6 (2%)	272	0.001389	0.822	0.16394	1	0.29809	1	0.38677	1	0.63713	1	0.80261	1	0.29506	1	0.076134	1	0.16494	1	0.12865	1
5q gain	3 (1%)	275	0.059833	1	0.11275	1	NA	NA	NA	NA	0.49439	1	0.77635	1	NA	NA	NA	NA	NA	NA	NA	NA
7p gain	46 (17%)	232	5.5322e-07	0.000348	1.0491e-06	0.000657	0.4133	1	0.56093	1	6.6096e-05	0.0405	0.021888	1	0.41817	1	0.96163	1	0.72994	1	0.90172	1
7q gain	43 (15%)	235	4.3593e-06	0.0027	1.7308e-06	0.00108	0.58591	1	0.55136	1	8.814e-05	0.0537	0.057204	1	0.41532	1	0.82945	1	0.72751	1	0.87023	1
8p gain	34 (12%)	244	8.9482e-14	5.69e-11	2.406e-07	0.000152	0.0051135	1	0.019326	1	0.0086806	1	0.00065681	0.393	0.31647	1	0.37935	1	0.33054	1	0.69029	1
8q gain	59 (21%)	219	1.9147e-15	1.22e-12	2.0523e-05	0.0127	0.0012962	0.77	0.0049163	1	0.010103	1	2.3759e-05	0.0146	0.022464	1	0.025809	1	0.099762	1	0.2441	1
9p gain	10 (4%)	268	0.00048099	0.289	0.66186	1	0.48418	1	0.19994	1	0.97025	1	0.65587	1	0.77425	1	0.2444	1	0.56235	1	0.17316	1
9q gain	20 (7%)	258	9.2249e-07	0.000579	0.37808	1	0.028107	1	0.011234	1	0.86924	1	0.15793	1	0.38743	1	0.071156	1	0.38664	1	0.48168	1
10p gain	7 (3%)	271	0.0030529	1	0.30176	1	0.78437	1	0.63505	1	1	1	0.094508	1	0.033888	1	0.034278	1	0.052636	1	0.080365	1
10q gain	8 (3%)	270	0.00099421	0.593	0.31905	1	0.040303	1	0.037622	1	0.96284	1	0.073332	1	0.27288	1	0.26619	1	0.12468	1	0.63879	1
11p gain	9 (3%)	269	0.0017022	1	0.29497	1	0.76789	1	0.58549	1	0.23625	1	0.26708	1	0.94284	1	1	1	1	1	0.81932	1
11q gain	9 (3%)	269	0.0017022	1	0.29497	1	0.76789	1	0.58549	1	0.23625	1	0.26708	1	0.94284	1	1	1	1	1	0.81932	1
12q gain	5 (2%)	273	0.25236	1	0.10321	1	0.84816	1	0.86319	1	0.4434	1	0.17763	1	0.90894	1	0.17658	1	1	1	0.27893	1
14q gain	5 (2%)	273	0.017849	1	0.036396	1	0.78437	1	0.63505	1	0.069991	1	0.056218	1	0.032925	1	0.22607	1	0.025306	1	0.10031	1
15q gain	3 (1%)	275	0.58247	1	1	1	NA	NA	NA	NA	0.79005	1	1	1	0.13599	1	0.25607	1	0.77715	1	0.77882	1
16p gain	14 (5%)	264	0.00046405	0.279	0.2541	1	0.52084	1	0.3895	1	0.69419	1	0.14791	1	0.24722	1	0.60641	1	0.2777	1	0.34322	1
16q gain	5 (2%)	273	0.0777	1	0.85998	1	0.67723	1	0.46645	1	0.47008	1	0.57325	1	0.82987	1	0.86251	1	1	1	1	1
17q gain	4 (1%)	274	0.01515	1	0.83319	1	0.47143	1	0.63505	1	0.67179	1	0.75114	1	0.89432	1	0.81439	1	0.83793	1	0.8304	1
18p gain	9 (3%)	269	0.00024861	0.15	0.6927	1	1	1	0.56384	1	0.38897	1	0.4031	1	0.6171	1	0.62695	1	1	1	1	1
18q gain	4 (1%)	274	0.01515	1	0.83319	1	1	1	0.38478	1	0.84276	1	0.34959	1	0.57024	1	0.69612	1	0.68819	1	0.69053	1
19p gain	3 (1%)	275	0.059833	1	0.50931	1	NA	NA	NA	NA	0.628	1	0.15232	1	NA	NA	NA	NA	NA	NA	NA	NA
19q gain	4 (1%)	274	0.01515	1	0.39143	1	0.78437	1	0.63505	1	0.45013	1	0.037583	1	NA	NA	NA	NA	NA	NA	NA	NA
20p gain	6 (2%)	272	0.098099	1	0.066159	1	0.37099	1	0.1451	1	0.097884	1	0.079802	1	0.36409	1	0.13111	1	0.23446	1	0.2329	1
20q gain	8 (3%)	270	0.015081	1	0.14296	1	0.62114	1	0.79785	1	0.38004	1	0.40895	1	0.82696	1	0.59822	1	0.90515	1	0.90731	1
21q gain	6 (2%)	272	0.001389	0.822	0.16394	1	0.44456	1	0.32596	1	0.20037	1	0.35566	1	0.43341	1	0.4532	1	0.27756	1	0.32945	1
1p loss	8 (3%)	270	0.015081	1	0.087005	1	0.25549	1	0.15469	1	0.056391	1	0.028728	1	0.27452	1	0.29382	1	0.14212	1	0.16489	1
2p loss	3 (1%)	275	0.059833	1	0.11275	1	NA	NA	NA	NA	0.49439	1	0.15232	1	0.63872	1	0.62207	1	0.52102	1	0.63951	1
2q loss	4 (1%)	274	0.01515	1	0.46301	1	NA	NA	NA	NA	0.61911	1	0.38413	1	0.63792	1	0.38716	1	0.2682	1	0.3195	1
3p loss	4 (1%)	274	0.2257	1	0.32058	1	NA	NA	NA	NA	0.28329	1	0.25382	1	0.25783	1	1	1	1	1	1	1
4p loss	9 (3%)	269	0.018893	1	0.32574	1	0.29809	1	1	1	0.039308	1	0.13312	1	0.038208	1	0.0028101	1	0.075603	1	0.049289	1
4q loss	6 (2%)	272	0.098099	1	0.51781	1	0.78437	1	0.38478	1	0.097884	1	0.2949	1	0.26686	1	0.096775	1	0.081766	1	0.11475	1
5p loss	4 (1%)	274	0.01515	1	0.39143	1	0.78437	1	1	1	0.45013	1	0.037583	1	0.96042	1	1	1	1	1	1	1
5q loss	8 (3%)	270	0.00013668	0.083	0.31905	1	0.25549	1	0.15469	1	0.29947	1	0.10335	1	0.72628	1	0.36535	1	1	1	0.71471	1
6p loss	9 (3%)	269	3.1823e-05	0.0195	0.0034206	1	0.25549	1	0.15469	1	0.0045495	1	0.0020567	1	0.56546	1	0.83236	1	0.91394	1	0.91591	1
6q loss	16 (6%)	262	2.0139e-06	0.00125	0.0018961	1	0.076129	1	0.50153	1	0.0090286	1	0.0043453	1	0.49932	1	0.68748	1	0.72891	1	0.87546	1
8p loss	85 (31%)	193	2.9108e-06	0.00181	1.1933e-08	7.55e-06	0.54279	1	0.90364	1	9.3381e-07	0.000585	6.9264e-05	0.0423	0.00055427	0.333	0.77601	1	0.42828	1	0.57194	1
8q loss	11 (4%)	267	4.2653e-06	0.00265	0.24546	1	0.72964	1	1	1	0.05154	1	0.0026188	1	0.20192	1	0.25356	1	0.22758	1	0.086536	1
9p loss	12 (4%)	266	0.00037262	0.225	0.81225	1	0.085491	1	0.34847	1	0.16295	1	0.29574	1	0.24633	1	0.12471	1	0.24561	1	0.25066	1
9q loss	5 (2%)	273	0.017849	1	0.4472	1	0.44456	1	0.86319	1	0.64823	1	0.75941	1	0.40331	1	0.4532	1	0.86333	1	0.8654	1
10p loss	18 (6%)	260	8.669e-06	0.00536	0.00096593	0.577	0.0068249	1	0.03105	1	0.0067729	1	0.015626	1	0.34164	1	0.55426	1	0.1797	1	0.4704	1
10q loss	22 (8%)	256	3.9804e-07	0.000251	0.025454	1	0.039237	1	0.049752	1	0.13706	1	0.065739	1	0.44464	1	0.5171	1	0.15922	1	0.20478	1
12p loss	26 (9%)	252	0.00045305	0.273	0.090147	1	0.1857	1	0.64669	1	0.095442	1	0.10178	1	0.86447	1	0.18911	1	0.31663	1	0.78444	1
12q loss	11 (4%)	267	0.00012586	0.0765	0.46564	1	0.29692	1	0.49508	1	0.29174	1	0.31248	1	0.51789	1	0.34673	1	0.63704	1	0.69459	1
13q loss	39 (14%)	239	1.1348e-07	7.17e-05	0.31758	1	0.54251	1	0.5449	1	0.91557	1	0.37	1	0.81476	1	0.91146	1	0.77599	1	0.79144	1
14q loss	10 (4%)	268	0.095797	1	0.21202	1	0.46398	1	0.34847	1	0.47405	1	0.45716	1	0.0012285	0.731	0.010483	1	0.00069517	0.416	0.0017035	1
15q loss	16 (6%)	262	7.1573e-05	0.0437	0.035177	1	0.041296	1	0.087854	1	0.22109	1	0.061362	1	0.18099	1	0.74633	1	0.1923	1	0.4704	1
16p loss	16 (6%)	262	0.0088661	1	0.18752	1	0.59861	1	0.59943	1	0.34404	1	0.36473	1	0.38752	1	0.62918	1	0.36443	1	0.56099	1
16q loss	53 (19%)	225	1.2742e-10	8.09e-08	0.0044948	1	0.49169	1	0.2994	1	0.054586	1	0.015726	1	0.61455	1	1	1	0.17239	1	0.3972	1
17p loss	38 (14%)	240	7.3949e-14	4.71e-11	0.0020805	1	0.0034438	1	0.014101	1	0.0019493	1	2.9995e-05	0.0184	0.69058	1	0.83163	1	0.68913	1	0.6156	1
17q loss	7 (3%)	271	0.0030529	1	0.019814	1	0.4517	1	0.31352	1	0.010925	1	0.098747	1	0.74014	1	0.88168	1	0.14212	1	0.16489	1
18p loss	34 (12%)	244	1.5787e-06	0.000987	0.028576	1	0.063325	1	0.079442	1	0.055444	1	0.021547	1	0.36461	1	0.49137	1	0.19894	1	0.26506	1
18q loss	50 (18%)	228	6.0253e-09	3.82e-06	0.031005	1	0.015976	1	0.018818	1	0.012186	1	0.014037	1	0.64612	1	0.74158	1	0.6801	1	0.76931	1
19p loss	9 (3%)	269	0.018893	1	0.76277	1	0.67723	1	1	1	0.67029	1	0.96365	1	0.45899	1	0.33909	1	0.39673	1	0.35687	1
19q loss	9 (3%)	269	0.018893	1	0.76277	1	0.67723	1	1	1	0.67029	1	0.96365	1	0.45899	1	0.33909	1	0.39673	1	0.35687	1
20p loss	10 (4%)	268	0.46251	1	0.035335	1	0.89585	1	1	1	0.83235	1	0.47745	1	0.7253	1	0.20403	1	0.91394	1	0.47863	1
20q loss	6 (2%)	272	0.098099	1	0.066159	1	1	1	0.86319	1	0.66866	1	0.16333	1	0.63815	1	0.66219	1	0.59668	1	0.29005	1
21q loss	9 (3%)	269	0.072327	1	0.29497	1	0.50529	1	0.44539	1	0.52778	1	0.18493	1	0.58097	1	0.42332	1	0.54501	1	0.81932	1
22q loss	19 (7%)	259	0.00019332	0.117	0.20325	1	0.44243	1	0.80454	1	0.29276	1	0.095853	1	0.788	1	0.63879	1	0.53398	1	0.6428	1
xq loss	18 (6%)	260	6.2886e-05	0.0385	0.0014273	0.842	0.19256	1	0.2354	1	0.0039961	1	0.026328	1	0.27757	1	0.28145	1	0.13952	1	0.18076	1
