		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	37 (11%)	294	8.7457e-06	0.00609	0.16804	1	0.0028436	1	0.095565	1	0.012413	1	0.38634	1	0.068329	1	0.20034	1	0.00038401	0.238	0.082666	1
1q gain	80 (24%)	251	1.5191e-10	1.16e-07	0.0031666	1	0.027419	1	0.1551	1	1.3883e-05	0.00951	0.0048394	1	0.00081084	0.488	0.001517	0.878	0.0070105	1	0.0034455	1
2p gain	56 (17%)	275	4.7241e-06	0.00334	0.017958	1	0.048369	1	0.94043	1	0.066113	1	0.23847	1	0.00025371	0.16	0.0038383	1	0.0036872	1	7.0046e-05	0.0461
2q gain	49 (15%)	282	0.00016011	0.103	0.28222	1	0.35161	1	0.55488	1	0.013353	1	0.081335	1	0.015464	1	0.037222	1	0.022177	1	0.0070926	1
3p gain	38 (11%)	293	0.015043	1	0.13214	1	0.78912	1	0.076053	1	0.64795	1	0.43651	1	0.565	1	0.1253	1	0.42024	1	0.045522	1
3q gain	62 (19%)	269	0.062067	1	0.25163	1	0.85153	1	0.32571	1	0.19291	1	0.062772	1	0.93174	1	0.77013	1	0.75512	1	0.37942	1
4p gain	12 (4%)	319	0.26029	1	0.85433	1	1	1	1	1	0.51693	1	0.47015	1	0.53573	1	0.3672	1	0.91477	1	0.45213	1
4q gain	8 (2%)	323	0.6455	1	0.8476	1	0.86675	1	0.72284	1	0.15796	1	0.62039	1	1	1	0.59736	1	0.78471	1	0.61154	1
5p gain	73 (22%)	258	5.7521e-16	4.5e-13	6.2019e-06	0.00435	0.27483	1	0.64047	1	8.1668e-06	0.0057	6.291e-05	0.0416	2.567e-05	0.0174	2.4247e-05	0.0164	0.00064884	0.394	5.1084e-06	0.0036
5q gain	29 (9%)	302	0.0020026	1	0.18589	1	0.64401	1	0.73335	1	0.093264	1	0.12498	1	0.091903	1	0.11806	1	0.1908	1	0.14352	1
6p gain	59 (18%)	272	2.1483e-09	1.63e-06	6.8716e-08	5.11e-05	0.10589	1	0.26568	1	0.00021885	0.139	7.5199e-05	0.0493	1.0494e-05	0.00726	0.00020581	0.131	0.00011605	0.0753	3.8027e-06	0.00271
6q gain	49 (15%)	282	1.0016e-08	7.55e-06	2.0137e-05	0.0137	0.12298	1	0.5549	1	5.9052e-05	0.0392	0.00049941	0.308	5.1503e-05	0.0342	0.02272	1	0.00034859	0.218	7.2155e-05	0.0474
7p gain	145 (44%)	186	1.2754e-11	9.82e-09	0.00029927	0.188	0.79402	1	0.90734	1	0.21727	1	0.10339	1	0.27288	1	0.10757	1	0.090369	1	0.0022724	1
7q gain	124 (37%)	207	1.184e-10	9.07e-08	0.0020462	1	0.93624	1	0.67188	1	0.57286	1	0.36252	1	0.94674	1	0.79482	1	0.63775	1	0.151	1
8p gain	140 (42%)	191	0.00023745	0.15	0.27418	1	0.48805	1	0.62074	1	0.29624	1	0.10594	1	0.7454	1	0.84995	1	0.040956	1	0.51602	1
8q gain	186 (56%)	145	0.0061755	1	0.012969	1	0.7121	1	0.071542	1	0.025644	1	0.30162	1	0.029064	1	0.042572	1	0.0007345	0.444	0.055726	1
9p gain	42 (13%)	289	0.15351	1	0.53442	1	0.55124	1	0.59035	1	0.35906	1	0.41467	1	0.67626	1	0.71036	1	0.80836	1	0.33282	1
9q gain	52 (16%)	279	0.21947	1	0.19563	1	0.31958	1	0.73152	1	0.60993	1	0.49297	1	0.83734	1	0.82855	1	0.8751	1	0.48421	1
10p gain	80 (24%)	251	4.4036e-14	3.43e-11	1.6955e-05	0.0116	0.10391	1	0.42873	1	0.00075022	0.453	0.019925	1	0.0079774	1	0.0005482	0.336	0.084886	1	0.0020873	1
10q gain	55 (17%)	276	1.2586e-12	9.77e-10	0.014041	1	0.12839	1	0.56216	1	0.010578	1	0.035786	1	0.017754	1	0.079787	1	0.2873	1	0.011747	1
11p gain	35 (11%)	296	0.040892	1	0.013306	1	0.89736	1	0.80951	1	0.24773	1	0.0071981	1	0.0014849	0.861	0.033142	1	0.20078	1	0.05157	1
11q gain	43 (13%)	288	0.0014084	0.82	0.0040734	1	0.87798	1	0.60774	1	0.27019	1	0.0059587	1	0.00032555	0.203	0.0093921	1	0.01401	1	0.0084291	1
12p gain	66 (20%)	265	0.012866	1	0.095296	1	0.24003	1	0.14063	1	0.15425	1	0.31244	1	0.070956	1	0.78958	1	0.010887	1	0.21687	1
12q gain	58 (18%)	273	0.038904	1	0.026825	1	0.4072	1	0.17937	1	0.95777	1	0.77667	1	0.68768	1	0.74544	1	0.1404	1	0.77857	1
13q gain	111 (34%)	220	7.5801e-11	5.82e-08	0.0021194	1	0.56677	1	0.34827	1	0.022201	1	0.79604	1	0.0013259	0.776	0.0025096	1	0.011681	1	0.00022315	0.142
14q gain	19 (6%)	312	0.0064689	1	0.27449	1	0.9326	1	0.5409	1	0.77801	1	0.92979	1	0.11507	1	0.93667	1	0.20218	1	0.72866	1
15q gain	26 (8%)	305	0.0016631	0.958	0.053579	1	0.23328	1	0.78275	1	0.026629	1	0.065976	1	0.62497	1	0.20937	1	0.56913	1	0.027464	1
16p gain	45 (14%)	286	0.14484	1	0.0548	1	0.38046	1	0.15083	1	0.066742	1	0.34266	1	0.76028	1	0.089634	1	0.94335	1	0.4946	1
16q gain	34 (10%)	297	0.27554	1	0.34214	1	0.6881	1	0.14579	1	0.19754	1	0.37282	1	0.70724	1	0.12968	1	1	1	0.88677	1
17p gain	21 (6%)	310	0.020162	1	0.59572	1	0.72668	1	0.20022	1	0.28335	1	0.73364	1	0.54203	1	0.094373	1	0.6014	1	0.79105	1
17q gain	40 (12%)	291	0.011753	1	0.28306	1	0.93671	1	0.94044	1	0.47311	1	0.35994	1	0.78749	1	0.80486	1	0.75078	1	1	1
18p gain	62 (19%)	269	6.4501e-05	0.0426	3.8134e-06	0.00271	0.10552	1	0.60964	1	0.015848	1	0.076015	1	0.0057434	1	0.00013264	0.0859	0.059501	1	0.0013403	0.783
18q gain	43 (13%)	288	0.0036774	1	0.002397	1	0.47308	1	0.48096	1	0.32454	1	0.64913	1	0.039531	1	0.022854	1	0.082549	1	0.1181	1
19p gain	41 (12%)	290	0.081537	1	0.55809	1	0.38239	1	0.057413	1	0.7426	1	0.73143	1	0.80648	1	0.63676	1	0.47243	1	0.74571	1
19q gain	56 (17%)	275	0.013816	1	0.19187	1	0.19205	1	0.11356	1	0.042381	1	0.1216	1	0.15713	1	0.19812	1	0.28512	1	0.23687	1
20p gain	182 (55%)	149	9.2617e-12	7.14e-09	0.00066863	0.405	0.084157	1	0.70427	1	0.00077729	0.469	0.0086284	1	0.00043762	0.271	5.9801e-05	0.0396	0.016774	1	0.00014161	0.0915
20q gain	209 (63%)	122	3.8705e-16	3.04e-13	9.5728e-10	7.29e-07	0.044012	1	0.97131	1	1.0186e-06	0.000743	7.5999e-05	0.0497	2.2642e-06	0.00163	1.0344e-09	7.87e-07	0.046325	1	2.3655e-09	1.79e-06
21q gain	20 (6%)	311	1.0633e-06	0.000774	0.00088233	0.528	0.14016	1	0.66643	1	0.010089	1	0.06556	1	0.01748	1	0.00015325	0.0988	0.11862	1	3.8414e-05	0.0257
22q gain	26 (8%)	305	0.00976	1	0.19382	1	0.83356	1	0.39183	1	0.23605	1	0.64508	1	0.45603	1	0.63886	1	0.3728	1	0.57548	1
xq gain	42 (13%)	289	0.00041119	0.255	0.019464	1	0.45962	1	0.15224	1	0.061565	1	0.34364	1	0.011206	1	0.45054	1	0.062274	1	0.036168	1
1p loss	43 (13%)	288	7.1949e-08	5.33e-05	0.0089249	1	0.0562	1	0.58642	1	0.035341	1	0.059196	1	0.006568	1	0.003413	1	0.2144	1	0.0158	1
1q loss	20 (6%)	311	3.5709e-05	0.024	0.0073767	1	0.032817	1	0.073549	1	0.4875	1	0.042426	1	0.35357	1	0.22144	1	0.45068	1	0.15547	1
2p loss	18 (5%)	313	0.0054312	1	0.019439	1	0.51989	1	0.76945	1	0.066288	1	0.28868	1	0.12768	1	0.10776	1	0.33316	1	0.53794	1
2q loss	20 (6%)	311	0.003145	1	0.0082866	1	0.85248	1	0.65263	1	0.050182	1	0.51104	1	0.050365	1	0.019811	1	0.22651	1	0.17129	1
3p loss	63 (19%)	268	5.1447e-06	0.00362	0.00092891	0.554	0.33146	1	0.45508	1	0.001772	1	0.00087074	0.522	0.0013946	0.813	0.056914	1	0.060689	1	0.014784	1
3q loss	38 (11%)	293	2.4461e-06	0.00176	2.585e-06	0.00186	0.19823	1	0.29154	1	7.4966e-06	0.00524	4.3125e-05	0.0289	4.7024e-05	0.0313	0.0012581	0.738	0.0058427	1	0.00447	1
4p loss	122 (37%)	209	4.2669e-16	3.35e-13	3.4557e-06	0.00247	0.28393	1	0.56048	1	0.00034921	0.218	0.001131	0.668	1.4668e-05	0.01	4.3289e-08	3.24e-05	0.0079152	1	2.22e-06	0.0016
4q loss	121 (37%)	210	7.1568e-18	5.63e-15	1.7235e-06	0.00125	0.070869	1	0.37419	1	0.0068676	1	0.001131	0.668	0.00017667	0.113	3.9811e-07	0.000292	0.030634	1	9.8079e-06	0.0068
5p loss	42 (13%)	289	1.1228e-05	0.00776	0.0013086	0.767	0.31692	1	0.44135	1	0.00060508	0.37	0.0036804	1	0.061322	1	0.017934	1	0.024088	1	0.0015935	0.921
5q loss	72 (22%)	259	4.3622e-12	3.37e-09	4.6763e-06	0.00331	0.61455	1	0.92903	1	2.3428e-07	0.000172	6.6329e-06	0.00464	0.00029954	0.188	1.1499e-06	0.000836	0.00064157	0.391	2.986e-08	2.24e-05
6p loss	36 (11%)	295	2.1085e-05	0.0143	0.0053109	1	0.14556	1	0.25578	1	0.024782	1	0.04082	1	0.21189	1	0.004332	1	0.1679	1	0.001145	0.674
6q loss	47 (14%)	284	0.00019211	0.123	0.0079498	1	0.7487	1	0.75213	1	0.030795	1	0.15389	1	0.55795	1	0.032012	1	0.70593	1	0.029602	1
7p loss	11 (3%)	320	0.0060993	1	0.097834	1	0.40456	1	0.78023	1	0.00053786	0.33	0.13908	1	0.1981	1	0.11769	1	0.010072	1	0.033412	1
7q loss	21 (6%)	310	2.8394e-05	0.0192	0.033217	1	0.44506	1	0.78203	1	0.0021568	1	0.055131	1	0.068593	1	0.034637	1	0.0023358	1	0.051079	1
8p loss	57 (17%)	274	7.8675e-07	0.000574	0.11525	1	0.38798	1	0.34086	1	0.0051747	1	0.0029042	1	0.0016588	0.957	0.0011003	0.651	0.0059593	1	0.039432	1
8q loss	17 (5%)	314	0.023176	1	0.44623	1	1	1	0.67906	1	0.86806	1	0.25492	1	0.31547	1	0.61369	1	0.8141	1	0.47033	1
9p loss	103 (31%)	228	6.8882e-18	5.43e-15	1.4347e-07	0.000106	0.0010367	0.616	0.03881	1	1.7164e-08	1.29e-05	5.8796e-05	0.039	0.00031725	0.199	8.3034e-06	0.00579	0.22891	1	4.0559e-06	0.00288
9q loss	72 (22%)	259	1.361e-08	1.02e-05	0.00086787	0.521	0.12991	1	0.31604	1	1.3103e-05	0.00903	0.0017511	1	0.0046699	1	0.0014257	0.828	0.074351	1	0.00037513	0.233
10p loss	38 (11%)	293	9.183e-06	0.00638	0.043116	1	0.60439	1	0.39936	1	0.019723	1	0.013874	1	0.014426	1	0.047078	1	0.1439	1	0.055992	1
10q loss	44 (13%)	287	4.7327e-08	3.53e-05	0.0017257	0.992	0.59277	1	0.5397	1	0.0010708	0.635	0.009405	1	0.058659	1	0.022854	1	0.53122	1	0.059332	1
11p loss	47 (14%)	284	2.9953e-06	0.00214	0.00086453	0.52	0.019592	1	0.70549	1	0.063472	1	0.019091	1	0.56526	1	0.022087	1	0.39832	1	0.030309	1
11q loss	43 (13%)	288	0.0065611	1	0.10703	1	0.51708	1	0.95544	1	0.71352	1	0.52845	1	0.63565	1	0.22111	1	0.71168	1	0.23603	1
12p loss	45 (14%)	286	5.5621e-12	4.29e-09	7.669e-08	5.68e-05	0.24882	1	0.51032	1	1.9188e-05	0.0131	0.00051941	0.319	0.0031587	1	3.7773e-05	0.0253	0.055086	1	1.7047e-07	0.000126
12q loss	34 (10%)	297	3.8533e-09	2.91e-06	1.8923e-05	0.0129	0.49706	1	1	1	0.0025631	1	0.10126	1	0.20042	1	0.0011744	0.691	0.4975	1	0.0025502	1
13q loss	30 (9%)	301	0.00016733	0.107	0.95104	1	0.67576	1	0.13801	1	0.27893	1	0.53939	1	0.72789	1	0.44538	1	0.31466	1	0.81864	1
14q loss	81 (24%)	250	4.7592e-08	3.55e-05	0.0052852	1	0.55905	1	0.47075	1	0.00060778	0.371	0.00025041	0.158	0.00046547	0.288	0.0023839	1	0.033075	1	2.0845e-05	0.0142
15q loss	67 (20%)	264	2.9901e-07	0.000219	4.5987e-05	0.0307	0.0051223	1	0.069268	1	7.7436e-05	0.0505	7.5199e-05	0.0493	0.00020942	0.133	1.2462e-05	0.0086	0.0024492	1	9.8419e-05	0.0641
16p loss	70 (21%)	261	5.545e-16	4.35e-13	3.4795e-06	0.00248	0.81171	1	0.80704	1	4.0839e-10	3.12e-07	5.3023e-07	0.000388	1.7087e-06	0.00124	0.00018322	0.117	3.1044e-06	0.00222	4.8594e-06	0.00343
16q loss	79 (24%)	252	1.1858e-13	9.24e-11	1.83e-07	0.000135	0.046392	1	0.56385	1	6.9722e-08	5.17e-05	1.3866e-05	0.00951	9.5166e-06	0.0066	7.6138e-05	0.0497	0.0029643	1	1.3331e-05	0.00917
17p loss	115 (35%)	216	2.8089e-20	2.22e-17	1.7645e-09	1.34e-06	0.46291	1	0.80875	1	4.4449e-06	0.00315	1.7356e-06	0.00125	0.00013374	0.0865	1.3807e-05	0.00949	0.0027818	1	4.5927e-08	3.43e-05
17q loss	54 (16%)	277	8.0678e-09	6.09e-06	3.3321e-05	0.0225	0.28263	1	1	1	0.0023238	1	0.00049941	0.308	0.00057635	0.353	0.00090041	0.538	0.054114	1	0.00023643	0.15
18p loss	92 (28%)	239	4.4081e-05	0.0294	0.62961	1	0.70275	1	0.13093	1	0.45118	1	0.30897	1	0.065836	1	0.47773	1	0.049827	1	0.365	1
18q loss	116 (35%)	215	2.1657e-08	1.63e-05	0.036353	1	0.33752	1	0.3656	1	0.012505	1	0.024223	1	0.0025468	1	0.013796	1	0.11751	1	0.012556	1
19p loss	81 (24%)	250	2.6518e-19	2.09e-16	3.1056e-12	2.4e-09	0.0099561	1	0.48511	1	6.1804e-13	4.8e-10	2.2237e-12	1.72e-09	5.4337e-07	0.000397	2.9459e-13	2.29e-10	0.00022803	0.145	5.7409e-11	4.41e-08
19q loss	62 (19%)	269	1.6224e-14	1.27e-11	5.8797e-10	4.49e-07	0.017418	1	0.10031	1	1.5523e-07	0.000115	2.4302e-06	0.00175	3.4151e-05	0.023	1.6973e-09	1.29e-06	0.00065592	0.398	5.0201e-08	3.73e-05
20p loss	16 (5%)	315	0.019282	1	0.00011287	0.0734	1	1	0.52548	1	0.00024897	0.157	0.26758	1	0.06761	1	0.75575	1	0.72614	1	0.35592	1
21q loss	120 (36%)	211	8.6661e-11	6.65e-08	0.00015444	0.0995	0.10129	1	0.27989	1	0.031027	1	6.6486e-05	0.0438	0.0055944	1	0.0066346	1	0.011693	1	0.012865	1
22q loss	101 (31%)	230	1.9651e-15	1.54e-12	2.6601e-06	0.00191	0.015069	1	0.4842	1	0.00097082	0.578	0.0017344	0.996	5.7469e-06	0.00403	3.8914e-08	2.91e-05	0.034187	1	1.3373e-06	0.000971
xq loss	41 (12%)	290	5.3265e-06	0.00374	0.0071426	1	0.47903	1	0.90111	1	0.037024	1	0.012185	1	0.048808	1	0.49937	1	0.022481	1	0.87916	1
