Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.047 0.223 0.29 3.0 -0.479 12.0 15.0 MAP3K8 0.016 0.082 0.249 2.0 -0.426 2.0 4.0 FOS -0.052 0.215 0.308 2.0 -0.468 12.0 14.0 PRKCA -0.017 0.132 0.243 1.0 -0.426 7.0 8.0 PTPN7 0.033 0.184 0.243 20.0 -0.427 8.0 28.0 HRAS 0.024 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.015 0.135 0.243 8.0 -0.428 5.0 13.0 NRAS 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.039 0.022 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.013 0.194 0.315 1.0 -0.539 7.0 8.0 MAP2K1 -0.054 0.189 -9999.0 0.0 -0.429 12.0 12.0 ELK1 0.022 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.045 0.165 -9999.0 0.0 -0.387 13.0 13.0 mol:GTP -0.0 0.001 0.003 2.0 -0.004 4.0 6.0 MAPK1 -0.067 0.229 0.282 1.0 -0.473 15.0 16.0 RAF1 -0.038 0.163 -9999.0 0.0 -0.389 12.0 12.0 KRAS 0.023 0.007 -9999.0 0.0 -9999.0 0.0 0.0