Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.027 0.124 0.405 21.0 -9999.0 0.0 21.0 KIRREL -0.03 0.155 -9999.0 0.0 -0.585 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.027 0.124 -9999.0 0.0 -0.405 21.0 21.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.037 0.099 -9999.0 0.0 -0.335 16.0 16.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.003 0.086 -9999.0 0.0 -0.281 16.0 16.0 FYN -0.019 0.105 -9999.0 0.0 -0.328 17.0 17.0 mol:Ca2+ -0.037 0.098 -9999.0 0.0 -0.332 16.0 16.0 mol:DAG -0.037 0.099 -9999.0 0.0 -0.334 16.0 16.0 NPHS2 -0.021 0.103 -9999.0 0.0 -0.466 11.0 11.0 mol:IP3 -0.037 0.099 -9999.0 0.0 -0.334 16.0 16.0 regulation of endocytosis -0.009 0.099 -9999.0 0.0 -0.306 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol -0.039 0.102 -9999.0 0.0 -0.344 16.0 16.0 establishment of cell polarity -0.027 0.124 -9999.0 0.0 -0.405 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 -0.004 0.099 -9999.0 0.0 -0.344 7.0 7.0 Nephrin/NEPH1/beta Arrestin2 -0.008 0.1 -9999.0 0.0 -0.31 16.0 16.0 NPHS1 -0.01 0.07 -9999.0 0.0 -0.454 5.0 5.0 Nephrin/NEPH1/podocin -0.019 0.105 -9999.0 0.0 -0.33 17.0 17.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.037 0.099 -9999.0 0.0 -0.335 16.0 16.0 CD2AP 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.037 0.099 -9999.0 0.0 -0.335 16.0 16.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.098 -9999.0 0.0 -0.306 16.0 16.0 cytoskeleton organization 0.004 0.1 -9999.0 0.0 -0.321 16.0 16.0 Nephrin/NEPH1 -0.017 0.088 -9999.0 0.0 -0.286 21.0 21.0 Nephrin/NEPH1/ZO-1 -0.03 0.093 -9999.0 0.0 -0.34 16.0 16.0