Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NUMBER.OF.LYMPH.NODES nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q PIK3CA 302 (32%) 641 0.38937 1 0.027989 1 0.77017 1 0.80382 1 0.87799 1 0.57481 1 1 1 0.0026355 1 0.93882 1 0.57164 1 CBFB 23 (2%) 920 0.88426 1 0.9729 1 0.78172 1 0.18297 1 0.078606 1 0.39181 1 0.20004 1 0.94425 1 1 1 0.44425 1 GATA3 76 (8%) 867 0.18127 1 0.0013207 0.93 0.24034 1 0.0305 1 0.71798 1 0.068176 1 0.53215 1 0.079329 1 0.51007 1 0.0080175 1 FOXA1 22 (2%) 921 0.00048566 0.344 0.00053996 0.382 0.92178 1 0.31686 1 0.91656 1 0.53853 1 1 1 0.0087255 1 0.15225 1 0.44428 1 SF3B1 16 (2%) 927 0.30845 1 0.36958 1 0.42222 1 0.63757 1 0.835 1 0.43364 1 1 1 0.93688 1 1 1 0.64886 1 TP53 282 (30%) 661 0.12818 1 0.0053304 1 0.19009 1 0.016877 1 0.15288 1 0.044365 1 0.06451 1 3.8992e-12 2.82e-09 0.060594 1 0.88747 1 CDH1 96 (10%) 847 0.15121 1 0.0093372 1 0.026137 1 1.4419e-06 0.00104 0.0064371 1 0.0039652 1 0.60987 1 1.24e-69 9.04e-67 0.0089802 1 0.19748 1 RUNX1 29 (3%) 914 0.85477 1 0.71841 1 0.57098 1 0.42843 1 0.36513 1 0.86262 1 1 1 0.0015156 1 0.67967 1 0.17611 1 PTEN 34 (4%) 909 0.98087 1 0.073215 1 0.057944 1 0.26177 1 0.52509 1 0.044874 1 1 1 0.11978 1 0.33763 1 0.43519 1 TBX3 26 (3%) 917 0.342 1 0.027901 1 0.60668 1 0.8545 1 0.59626 1 0.85047 1 1 1 0.2771 1 1 1 0.50019 1 MAP2K4 32 (3%) 911 0.72394 1 0.41089 1 0.94901 1 0.30253 1 0.48309 1 0.58613 1 1 1 0.22025 1 0.69549 1 0.54827 1 MLL3 66 (7%) 877 0.15738 1 3.1598e-05 0.0225 0.7042 1 0.63296 1 0.092426 1 0.53829 1 1 1 0.86019 1 0.57744 1 0.78872 1 MAP3K1 68 (7%) 875 0.95613 1 0.0046973 1 0.7133 1 0.46141 1 0.91944 1 0.36899 1 1 1 0.76472 1 0.78167 1 0.017132 1 NCOR1 41 (4%) 902 0.66594 1 0.34202 1 0.93779 1 0.56749 1 0.94222 1 0.30873 1 1 1 0.66252 1 0.86113 1 0.45324 1 RB1 19 (2%) 924 0.56904 1 0.16524 1 0.46533 1 0.34985 1 0.75701 1 0.4023 1 0.16805 1 0.88622 1 0.30622 1 0.46849 1 CTCF 17 (2%) 926 0.12041 1 0.83107 1 0.53671 1 0.1864 1 0.61877 1 1 1 1 1 0.4882 1 0.42113 1 0.032739 1 THEM5 11 (1%) 932 0.53685 1 0.20774 1 0.6508 1 0.036527 1 0.38554 1 1 1 1 1 0.0080133 1 0.73883 1 0.36374 1 GPS2 10 (1%) 933 0.4671 1 0.14052 1 0.99753 1 0.080564 1 0.28997 1 1 1 1 1 0.85583 1 0.48798 1 0.51923 1 RPGR 17 (2%) 926 0.46947 1 0.28994 1 0.90276 1 0.79509 1 0.20483 1 0.58562 1 1 1 0.98427 1 0.78977 1 0.00062759 0.442 DNAH12 17 (2%) 926 0.67581 1 0.5122 1 0.91628 1 0.71845 1 0.17577 1 1 1 1 1 0.64362 1 0.59302 1 0.28447 1 CDKN1B 9 (1%) 934 0.99246 1 0.91998 1 0.18607 1 0.034544 1 0.013794 1 0.06743 1 1 1 0.98223 1 1 1 0.11391 1 ZFP36L1 9 (1%) 934 0.36969 1 0.3716 1 0.95312 1 0.78765 1 0.89399 1 1 1 1 1 0.97277 1 0.46025 1 0.053465 1 ASB10 8 (1%) 935 0.078529 1 0.51699 1 0.92811 1 0.76356 1 0.1746 1 1 1 1 1 0.1683 1 1 1 0.38204 1 HIST1H3B 10 (1%) 933 0.89578 1 0.051884 1 0.53625 1 0.56119 1 0.67768 1 1 1 1 1 0.95624 1 0.48798 1 0.4674 1 FAM86B1 8 (1%) 935 0.69635 1 0.082841 1 0.89395 1 0.90828 1 0.82399 1 0.33801 1 1 1 0.91546 1 0.4497 1 2.0997e-07 0.000152 PIK3R1 15 (2%) 928 0.0094094 1 0.2904 1 0.43802 1 1 1 0.37615 1 0.30436 1 1 1 0.90355 1 1 1 0.0079023 1 MYH9 19 (2%) 924 0.61147 1 0.40711 1 0.72455 1 0.83369 1 0.3027 1 0.62895 1 1 1 0.1039 1 0.078283 1 0.00058794 0.415 CASP8 10 (1%) 933 0.83811 1 0.58613 1 0.78529 1 0.92922 1 0.35447 1 1 1 1 1 0.61575 1 1 1 1.4254e-06 0.00103 COL6A5 23 (2%) 920 0.34034 1 0.38373 1 0.99654 1 0.90613 1 0.97349 1 1 1 1 1 0.22169 1 0.49608 1 0.68826 1 TBL1XR1 10 (1%) 933 0.87764 1 0.2106 1 0.37847 1 0.088963 1 0.029011 1 0.13076 1 1 1 0.85912 1 1 1 0.30996 1 ASXL2 16 (2%) 927 0.0063031 1 0.25483 1 0.80941 1 0.9643 1 0.13571 1 0.78116 1 1 1 0.8875 1 1 1 0.0001949 0.138 ARID1A 27 (3%) 916 0.52172 1 0.77692 1 0.5845 1 0.35672 1 0.26111 1 1 1 1 1 0.70961 1 0.66787 1 0.94125 1 AQP12A 6 (1%) 937 0.52553 1 0.39591 1 0.99927 1 0.67164 1 0.22277 1 0.57186 1 1 1 0.89165 1 0.36455 1 0.92678 1 EPDR1 5 (1%) 938 0.53166 1 0.28143 1 0.70531 1 0.37679 1 0.24469 1 1 1 1 1 0.88339 1 1 1 0.76144 1 ERBB2 21 (2%) 922 0.19532 1 0.11025 1 0.78177 1 0.19095 1 0.080527 1 1 1 0.18418 1 0.66522 1 0.46561 1 0.5255 1 MYB 12 (1%) 931 0.17509 1 0.12853 1 0.78067 1 0.4128 1 0.96486 1 0.50173 1 1 1 0.42471 1 0.34542 1 0.011277 1 TMEM151B 5 (1%) 938 0.57588 1 0.49044 1 0.61036 1 0.31356 1 0.87361 1 1 1 1 1 0.99722 1 0.32918 1 0.0049793 1 GALNTL6 5 (1%) 938 0.49543 1 0.18349 1 0.99914 1 1 1 0.60567 1 1 1 1 1 0.9414 1 0.15025 1 0.24863 1 AKD1 18 (2%) 925 0.70076 1 0.15375 1 0.74124 1 0.79574 1 0.6024 1 0.60706 1 1 1 0.74212 1 0.30313 1 0.1514 1 AARS 8 (1%) 935 0.57342 1 0.18377 1 0.99286 1 0.1622 1 0.63254 1 0.66027 1 1 1 0.98434 1 0.69752 1 0.53462 1 HLA-C 9 (1%) 934 0.60213 1 0.15977 1 0.95783 1 0.22588 1 0.89399 1 0.38856 1 1 1 0.98223 1 0.72423 1 0.25355 1 GPRIN2 10 (1%) 933 0.96445 1 0.35713 1 0.88462 1 0.92922 1 0.35447 1 0.67977 1 1 1 0.40745 1 0.48798 1 1.7272e-14 1.25e-11 TRPM5 11 (1%) 932 0.59127 1 0.73376 1 0.42607 1 0.74329 1 0.70862 1 0.69419 1 0.0042627 1 0.011768 1 0.19153 1 4.546e-06 0.00325 ANKRD12 17 (2%) 926 0.29077 1 0.17055 1 0.96078 1 0.5889 1 0.63702 1 0.35787 1 1 1 0.81025 1 0.42113 1 0.00036093 0.256 FBXW7 14 (1%) 929 0.74304 1 0.61327 1 0.77461 1 0.27027 1 0.63278 1 0.74557 1 1 1 0.84514 1 1 1 0.0041883 1 PRICKLE3 11 (1%) 932 0.90907 1 0.29335 1 0.062248 1 0.021165 1 0.95236 1 0.20617 1 1 1 0.84706 1 0.19153 1 0.00018076 0.129 WDR52 16 (2%) 927 0.34773 1 0.38262 1 0.67656 1 0.61745 1 0.18875 1 0.43364 1 0.14331 1 0.75806 1 1 1 8.5581e-08 6.19e-05 CDC42EP1 4 (0%) 939 0.39524 1 0.5681 1 0.0045464 1 1 1 0.43822 1 1 1 1 1 0.96607 1 1 1 0.30792 1 ERBB3 18 (2%) 925 1.7164e-05 0.0123 0.14795 1 0.43291 1 0.065132 1 0.4624 1 1 1 1 1 0.85895 1 0.0028726 1 0.72423 1 FHOD3 13 (1%) 930 0.15017 1 0.074689 1 0.99712 1 0.49495 1 0.77954 1 0.72773 1 0.11792 1 0.80682 1 0.53875 1 0.052416 1 PTHLH 7 (1%) 936 0.50041 1 0.24447 1 0.83303 1 1 1 0.12877 1 1 1 1 1 0.99163 1 0.68021 1 3.3397e-41 2.43e-38 SHISA4 5 (1%) 938 0.46284 1 0.88647 1 0.99308 1 0.50671 1 0.5206 1 0.50664 1 1 1 0.99722 1 0.63138 1 0.1498 1 KCNN3 9 (1%) 934 0.14858 1 0.5639 1 0.81572 1 0.41901 1 0.513 1 0.16301 1 1 1 0.58379 1 1 1 0.067489 1 FGFR2 10 (1%) 933 0.15402 1 0.37562 1 0.56361 1 0.014489 1 0.69694 1 0.43736 1 0.091864 1 0.83846 1 1 1 0.0018059 1 HLA-DRB5 6 (1%) 937 0.5479 1 0.23566 1 0.97726 1 0.67164 1 0.46713 1 1 1 1 1 0.94441 1 1 1 3.6763e-06 0.00264 ICOSLG 6 (1%) 937 0.46814 1 0.10515 1 0.63148 1 0.88068 1 0.73756 1 0.57186 1 1 1 0.94441 1 1 1 0.73738 1 GYG2 8 (1%) 935 0.58957 1 0.45658 1 0.43364 1 0.83405 1 0.78794 1 0.66027 1 1 1 0.95359 1 0.23982 1 3.9802e-06 0.00285 PPEF1 11 (1%) 932 0.036417 1 0.47674 1 0.99676 1 1 1 0.36991 1 1 1 1 1 0.93445 1 0.525 1 0.076077 1 MAP4K1 9 (1%) 934 0.46673 1 0.6908 1 0.86663 1 0.5145 1 0.26109 1 1 1 1 1 0.97277 1 1 1 0.46197 1 ZNF41 11 (1%) 932 0.48792 1 0.85393 1 0.9312 1 0.66852 1 0.54956 1 0.48399 1 1 1 0.97805 1 0.73883 1 0.3893 1 FBXO17 5 (1%) 938 0.0022596 1 0.64164 1 0.98106 1 0.50671 1 0.1637 1 0.18278 1 1 1 0.99722 1 1 1 0.61326 1 HRNR 31 (3%) 912 0.149 1 0.28451 1 0.35229 1 0.12457 1 0.12708 1 0.75589 1 1 1 0.92916 1 0.11167 1 1.0886e-05 0.00778 STAG2 13 (1%) 930 0.013843 1 0.040267 1 0.82991 1 0.9517 1 0.88624 1 0.25347 1 1 1 0.59835 1 1 1 0.73111 1 CEP57 4 (0%) 939 0.24184 1 0.21199 1 0.94862 1 0.52416 1 0.13887 1 0.43158 1 1 1 0.96607 1 0.58422 1 0.87803 1 SPRR2B 3 (0%) 940 0.71889 1 0.36607 1 0.99836 1 0.7322 1 1 1 1 1 1 1 0.9838 1 1 1 0.011209 1 ZFP36L2 7 (1%) 936 0.43066 1 0.94349 1 0.98419 1 0.90085 1 0.92746 1 1 1 1 1 0.99163 1 0.11331 1 0.0065389 1 DMXL2 18 (2%) 925 0.74477 1 0.21151 1 0.35717 1 0.077427 1 0.05978 1 0.79223 1 0.15987 1 1.763e-28 1.28e-25 0.30313 1 3.5584e-29 2.59e-26 ZBTB7C 5 (1%) 938 0.54156 1 0.69554 1 0.95795 1 1 1 0.16809 1 1 1 1 1 0.46175 1 0.32918 1 0.95146 1 MUC5B 32 (3%) 911 0.82504 1 0.78707 1 0.067017 1 0.55008 1 0.78804 1 0.40548 1 1 1 3.9008e-06 0.0028 1 1 0.94034 1 XBP1 4 (0%) 939 1.9175e-05 0.0137 0.026483 1 0.98627 1 0.79368 1 0.381 1 1 1 1 1 0.74138 1 0.32896 1 NA NA FXYD5 4 (0%) 939 0.77196 1 0.92297 1 0.87542 1 0.151 1 0.84218 1 1 1 1 1 0.74138 1 1 1 0.011209 1 ATXN2 15 (2%) 928 0.59896 1 0.11767 1 0.96353 1 0.57452 1 0.68617 1 1 1 1 1 0.98338 1 0.57305 1 0.54946 1 CCL13 4 (0%) 939 0.34231 1 0.15912 1 0.9795 1 0.65093 1 0.84218 1 1 1 1 1 0.74138 1 0.58422 1 0.011209 1