Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.094 0.199 0.64 108.0 -9999.0 0.0 108.0 KIRREL -0.084 0.25 -9999.0 0.0 -0.809 108.0 108.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.094 0.199 -9999.0 0.0 -0.642 108.0 108.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.068 0.151 -9999.0 0.0 -0.491 108.0 108.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.042 0.111 -9999.0 0.0 -0.364 108.0 108.0 FYN -0.063 0.145 -9999.0 0.0 -0.47 108.0 108.0 mol:Ca2+ -0.067 0.15 -9999.0 0.0 -0.486 108.0 108.0 mol:DAG -0.068 0.15 -9999.0 0.0 -0.488 108.0 108.0 NPHS2 -0.008 0.029 -9999.0 0.0 -0.284 4.0 4.0 mol:IP3 -0.068 0.15 -9999.0 0.0 -0.488 108.0 108.0 regulation of endocytosis -0.035 0.143 -9999.0 0.0 -0.438 108.0 108.0 Nephrin/NEPH1/podocin/Cholesterol -0.07 0.154 -9999.0 0.0 -0.499 108.0 108.0 establishment of cell polarity -0.094 0.199 -9999.0 0.0 -0.64 108.0 108.0 Nephrin/NEPH1/podocin/NCK1-2 -0.055 0.139 -9999.0 0.0 -0.447 108.0 108.0 Nephrin/NEPH1/beta Arrestin2 -0.036 0.145 -9999.0 0.0 -0.444 108.0 108.0 NPHS1 -0.05 0.106 -9999.0 0.0 -0.355 16.0 16.0 Nephrin/NEPH1/podocin -0.064 0.146 -9999.0 0.0 -0.473 108.0 108.0 TJP1 -0.001 0.025 -9999.0 0.0 -0.802 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.068 0.151 -9999.0 0.0 -0.491 108.0 108.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.286 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.068 0.151 -9999.0 0.0 -0.491 108.0 108.0 GRB2 -0.0 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.073 0.17 -9999.0 0.0 -0.513 116.0 116.0 cytoskeleton organization -0.053 0.139 -9999.0 0.0 -0.455 108.0 108.0 Nephrin/NEPH1 -0.068 0.149 -9999.0 0.0 -0.482 108.0 108.0 Nephrin/NEPH1/ZO-1 -0.074 0.164 -9999.0 0.0 -0.531 108.0 108.0