Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.056 0.204 0.303 2.0 -0.394 180.0 182.0 MAP3K8 0.01 0.046 -9999.0 0.0 -0.581 5.0 5.0 FOS -0.02 0.144 0.32 2.0 -0.445 49.0 51.0 PRKCA -0.002 0.088 0.241 1.0 -0.583 21.0 22.0 PTPN7 0.021 0.06 0.25 54.0 -9999.0 0.0 54.0 HRAS 0.024 0.021 0.261 7.0 -9999.0 0.0 7.0 PRKCB 0.006 0.08 0.254 18.0 -0.584 14.0 32.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.025 0.036 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.008 0.091 -9999.0 0.0 -0.801 5.0 5.0 MAP2K1 -0.011 0.119 -9999.0 0.0 -0.509 40.0 40.0 ELK1 0.006 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.012 0.1 -9999.0 0.0 -0.489 36.0 36.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 301.0 301.0 MAPK1 -0.009 0.124 -9999.0 0.0 -0.459 42.0 42.0 RAF1 -0.011 0.099 -9999.0 0.0 -0.485 36.0 36.0 KRAS 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0