Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	103 (67%)	51	0.17129	1	0.019777	1	0.037387	1	0.21809	1	0.38769	1	0.49819	1	0.25177	1	0.60069	1	0.25766	1
PIK3CA	26 (17%)	128	0.3349	1	0.32088	1	0.033771	1	0.11604	1	0.33202	1	0.48166	1	1	1	0.51361	1	0.41633	1
BRAF	20 (13%)	134	4.9591e-07	6.65e-05	1.2172e-07	1.64e-05	0.00010077	0.0134	0.72185	1	0.92618	1	0.00086639	0.113	0.3531	1	0.46154	1	1	1
KRAS	58 (38%)	96	0.025005	1	0.00072522	0.0957	0.83608	1	0.70357	1	0.75196	1	0.51281	1	0.45525	1	0.6257	1	0.28277	1
TP53	74 (48%)	80	0.0023293	0.3	0.012708	1	2.1674e-08	2.95e-06	0.26836	1	0.37976	1	0.1298	1	1	1	0.61993	1	1	1
FBXW7	29 (19%)	125	0.2264	1	0.093025	1	0.0018259	0.237	0.0037983	0.486	0.23259	1	1	1	0.48019	1	1	1	0.47418	1
NRAS	15 (10%)	139	0.077327	1	0.38017	1	0.86746	1	0.46546	1	0.33213	1	0.84488	1	1	1	1	1	1	1
SMAD4	18 (12%)	136	0.30252	1	0.58694	1	0.007209	0.908	0.85217	1	0.49482	1	0.66342	1	1	1	1	1	1	1
FAM123B	19 (12%)	135	0.20975	1	0.0069761	0.886	0.024897	1	0.28621	1	0.42194	1	0.3571	1	1	1	0.42457	1	0.33826	1
SOX9	9 (6%)	145	0.23526	1	0.21364	1	0.39756	1	0.23084	1	0.46084	1	1	1	1	1	1	1	1	1
ACVR2A	8 (5%)	146	0.044979	1	0.2961	1	0.054191	1	0.19948	1	0.66829	1	0.17084	1	1	1	1	1	0.16182	1
TNFRSF10C	6 (4%)	148	0.38104	1	0.67607	1	0.11867	1	0.67994	1	0.16933	1	0.24814	1	1	1	1	1	1	1
ACOT4	3 (2%)	151	0.66496	1	0.39097	1	0.74954	1	NA	NA	NA	NA	0.22539	1	1	1	1	1	1	1
SMAD2	10 (6%)	144	0.099491	1	0.19002	1	0.049712	1	1	1	0.37729	1	0.8179	1	1	1	1	1	1	1
PCBP1	4 (3%)	150	0.32974	1	0.55218	1	0.36776	1	NA	NA	NA	NA	1	1	1	1	1	1	1	1
GGT1	3 (2%)	151	NA	NA	NA	NA	0.35487	1	NA	NA	NA	NA	1	1	1	1	1	1	1	1