Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.133 0.527 26.0 -9999.0 0.0 26.0 KIRREL 0.004 0.039 -9999.0 0.0 -0.323 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.133 -9999.0 0.0 -0.528 26.0 26.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.012 0.115 -9999.0 0.0 -0.406 29.0 29.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.007 0.066 -9999.0 0.0 -0.452 1.0 1.0 FYN -0.011 0.097 -9999.0 0.0 -0.355 29.0 29.0 mol:Ca2+ -0.008 0.109 -9999.0 0.0 -0.397 29.0 29.0 mol:DAG -0.007 0.11 -9999.0 0.0 -0.398 29.0 29.0 NPHS2 -0.005 0.072 -9999.0 0.0 -0.716 4.0 4.0 mol:IP3 -0.007 0.11 -9999.0 0.0 -0.398 29.0 29.0 regulation of endocytosis -0.001 0.093 -9999.0 0.0 -0.331 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol -0.015 0.11 -9999.0 0.0 -0.405 29.0 29.0 establishment of cell polarity -0.021 0.133 -9999.0 0.0 -0.527 26.0 26.0 Nephrin/NEPH1/podocin/NCK1-2 0.001 0.103 -9999.0 0.0 -0.363 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 -0.0 0.094 -9999.0 0.0 -0.335 29.0 29.0 NPHS1 -0.034 0.172 -9999.0 0.0 -0.703 26.0 26.0 Nephrin/NEPH1/podocin -0.009 0.098 -9999.0 0.0 -0.357 29.0 29.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.007 0.11 -9999.0 0.0 -0.4 29.0 29.0 CD2AP 0.002 0.055 -9999.0 0.0 -0.32 12.0 12.0 Nephrin/NEPH1/podocin/GRB2 -0.007 0.11 -9999.0 0.0 -0.4 29.0 29.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.011 0.104 -9999.0 0.0 -0.372 29.0 29.0 cytoskeleton organization 0.006 0.084 -9999.0 0.0 -0.369 4.0 4.0 Nephrin/NEPH1 -0.013 0.098 -9999.0 0.0 -0.385 26.0 26.0 Nephrin/NEPH1/ZO-1 -0.008 0.11 -9999.0 0.0 -0.426 26.0 26.0