Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	160 (72%)	63	0.0077318	1	0.027115	1	0.11926	1	NA	NA	0.46589	1	0.46065	1	0.38059	1	0.18736	1	0.34002	1	0.8373	1
FBXW7	38 (17%)	185	0.062581	1	0.045513	1	2.6009e-05	0.00541	NA	NA	0.012204	1	0.03617	1	0.0014305	0.289	0.44204	1	0.41557	1	0.15614	1
NRAS	20 (9%)	203	0.047779	1	0.12727	1	0.19923	1	NA	NA	0.90948	1	0.47408	1	0.191	1	1	1	0.26773	1	1	1
BRAF	22 (10%)	201	2.8425e-06	0.000594	1.4128e-07	2.97e-05	0.00033235	0.0678	NA	NA	0.48227	1	0.30406	1	0.47318	1	0.27664	1	1	1	0.68359	1
KRAS	96 (43%)	127	7.8588e-05	0.0162	4.2343e-05	0.00877	0.32238	1	0.10714	1	0.56454	1	1	1	0.0016464	0.331	0.71614	1	0.021757	1	0.043066	1
TP53	119 (53%)	104	0.0020608	0.412	0.0004927	0.1	1.1469e-10	2.42e-08	NA	NA	0.56182	1	0.75484	1	0.025255	1	0.73557	1	0.030673	1	0.56715	1
SMAD4	26 (12%)	197	0.03221	1	0.28911	1	0.064649	1	NA	NA	0.82737	1	0.33919	1	0.58886	1	1	1	1	1	1	1
FAM123B	25 (11%)	198	0.078731	1	0.092448	1	0.0091227	1	NA	NA	0.34473	1	0.5876	1	0.049374	1	1	1	1	1	1	1
PIK3CA	33 (15%)	190	0.20759	1	0.56931	1	0.00031971	0.0655	NA	NA	0.067347	1	0.12884	1	0.082572	1	1	1	0.16455	1	1	1
SMAD2	15 (7%)	208	0.13416	1	0.51785	1	0.16063	1	NA	NA	0.59205	1	0.13321	1	0.71023	1	1	1	1	1	1	1
TCF7L2	18 (8%)	205	1	1	0.41637	1	0.0023949	0.477	NA	NA	0.8363	1	0.89617	1	0.35285	1	1	1	1	1	1	1
ACVR2A	9 (4%)	214	0.0071729	1	0.18431	1	0.023577	1	NA	NA	0.095237	1	0.46856	1	1	1	1	1	0.17286	1	1	1
SOX9	10 (4%)	213	0.12913	1	0.12286	1	0.0085594	1	NA	NA	0.18915	1	0.694	1	0.77282	1	1	1	1	1	1	1
ELF3	6 (3%)	217	0.36312	1	0.81051	1	0.27256	1	NA	NA	0.54372	1	0.43551	1	0.049637	1	1	1	1	1	1	1
CRTC1	6 (3%)	217	0.12306	1	0.16488	1	0.27256	1	NA	NA	0.17545	1	0.48214	1	0.77507	1	1	1	1	1	1	1
TNFRSF10C	6 (3%)	217	0.31707	1	0.28709	1	0.70688	1	NA	NA	0.27762	1	0.378	1	0.22297	1	1	1	1	1	1	1
KIAA1804	15 (7%)	208	0.27147	1	0.39438	1	0.027963	1	NA	NA	0.50609	1	0.47408	1	0.71023	1	1	1	1	1	1	1
KRTAP5-5	4 (2%)	219	0.3272	1	0.48238	1	0.83918	1	NA	NA	0.38532	1	1	1	1	1	1	1	1	1	1	1
PTEN	7 (3%)	216	0.027588	1	0.33674	1	0.069995	1	NA	NA	0.54372	1	0.43551	1	0.14798	1	1	1	0.34726	1	0.29788	1
ACOT4	3 (1%)	220	0.25523	1	0.48995	1	0.79228	1	NA	NA	NA	NA	NA	NA	0.5229	1	1	1	1	1	1	1
MYO1B	13 (6%)	210	0.0086846	1	0.0088707	1	0.0047945	0.949	NA	NA	0.021464	1	0.46856	1	0.17458	1	1	1	1	1	1	1
PCBP1	6 (3%)	217	0.23388	1	0.81051	1	0.79454	1	NA	NA	0.64843	1	0.48214	1	1	1	1	1	1	1	1	1
GGT1	3 (1%)	220	NA	NA	NA	NA	0.16176	1	NA	NA	NA	NA	NA	NA	0.5229	1	1	1	1	1	1	1
ACVR1B	14 (6%)	209	0.37438	1	0.31631	1	0.098558	1	NA	NA	0.7346	1	0.37567	1	0.85966	1	1	1	0.58058	1	1	1