Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.012 0.098 0.3 13.0 -9999.0 0.0 13.0 KIRREL -0.004 0.127 -9999.0 0.0 -0.411 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.012 0.099 -9999.0 0.0 -0.3 13.0 13.0 PLCG1 0.026 0.037 -9999.0 0.0 -0.402 1.0 1.0 ARRB2 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.023 0.015 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.041 0.089 -9999.0 0.0 -0.227 13.0 13.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.061 -9999.0 0.0 -0.218 9.0 9.0 FYN -0.019 0.076 0.152 11.0 -0.216 13.0 24.0 mol:Ca2+ 0.036 0.093 -9999.0 0.0 -0.241 13.0 13.0 mol:DAG 0.037 0.094 -9999.0 0.0 -0.242 13.0 13.0 NPHS2 0.019 0.027 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.037 0.094 -9999.0 0.0 -0.242 13.0 13.0 regulation of endocytosis 0.028 0.077 -9999.0 0.0 -0.207 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.027 0.081 -9999.0 0.0 -0.222 13.0 13.0 establishment of cell polarity 0.012 0.098 -9999.0 0.0 -0.3 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.058 0.09 -9999.0 0.0 -0.21 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.03 0.079 -9999.0 0.0 -0.209 13.0 13.0 NPHS1 0.019 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.025 0.077 -9999.0 0.0 -0.217 13.0 13.0 TJP1 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.033 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.038 0.095 -9999.0 0.0 -0.242 13.0 13.0 CD2AP 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.045 0.086 -9999.0 0.0 -0.227 12.0 12.0 GRB2 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.034 0.094 0.156 12.0 -0.221 22.0 34.0 cytoskeleton organization -0.016 0.063 0.196 1.0 -0.244 8.0 9.0 Nephrin/NEPH1 0.015 0.069 -9999.0 0.0 -0.204 13.0 13.0 Nephrin/NEPH1/ZO-1 0.03 0.087 -9999.0 0.0 -0.24 13.0 13.0