Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.054 0.173 0.603 37.0 -9999.0 0.0 37.0 KIRREL -0.012 0.119 -9999.0 0.0 -0.666 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.054 0.174 -9999.0 0.0 -0.605 37.0 37.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.05 0.159 -9999.0 0.0 -0.544 34.0 34.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.108 -9999.0 0.0 -0.569 6.0 6.0 FYN -0.029 0.153 -9999.0 0.0 -0.493 35.0 35.0 mol:Ca2+ -0.049 0.157 -9999.0 0.0 -0.538 34.0 34.0 mol:DAG -0.05 0.158 -9999.0 0.0 -0.541 34.0 34.0 NPHS2 -0.022 0.13 -9999.0 0.0 -0.847 10.0 10.0 mol:IP3 -0.05 0.158 -9999.0 0.0 -0.541 34.0 34.0 regulation of endocytosis -0.043 0.137 -9999.0 0.0 -0.478 28.0 28.0 Nephrin/NEPH1/podocin/Cholesterol -0.051 0.162 -9999.0 0.0 -0.553 34.0 34.0 establishment of cell polarity -0.054 0.173 -9999.0 0.0 -0.603 37.0 37.0 Nephrin/NEPH1/podocin/NCK1-2 -0.045 0.146 -9999.0 0.0 -0.499 34.0 34.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.147 -9999.0 0.0 -0.486 28.0 28.0 NPHS1 -0.044 0.197 -9999.0 0.0 -0.828 25.0 25.0 Nephrin/NEPH1/podocin -0.047 0.148 -9999.0 0.0 -0.497 35.0 35.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.05 0.159 -9999.0 0.0 -0.544 34.0 34.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.05 0.159 -9999.0 0.0 -0.544 34.0 34.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.056 0.196 -9999.0 0.0 -0.524 57.0 57.0 cytoskeleton organization -0.005 0.141 -9999.0 0.0 -0.758 6.0 6.0 Nephrin/NEPH1 -0.04 0.13 -9999.0 0.0 -0.452 37.0 37.0 Nephrin/NEPH1/ZO-1 -0.044 0.142 -9999.0 0.0 -0.535 29.0 29.0