Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.006 0.097 0.304 36.0 -9999.0 0.0 36.0 KIRREL 0.01 0.081 -9999.0 0.0 -0.447 12.0 12.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.006 0.098 -9999.0 0.0 -0.305 36.0 36.0 PLCG1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.027 0.092 -9999.0 0.0 -0.319 13.0 13.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.005 0.053 -9999.0 0.0 -0.253 10.0 10.0 FYN -0.012 0.083 0.271 10.0 -0.295 13.0 23.0 mol:Ca2+ 0.027 0.089 -9999.0 0.0 -0.311 12.0 12.0 mol:DAG 0.027 0.089 -9999.0 0.0 -0.313 12.0 12.0 NPHS2 -0.012 0.067 -9999.0 0.0 -0.41 10.0 10.0 mol:IP3 0.027 0.089 -9999.0 0.0 -0.313 12.0 12.0 regulation of endocytosis 0.025 0.078 -9999.0 0.0 -0.276 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.015 0.086 -9999.0 0.0 -0.238 40.0 40.0 establishment of cell polarity 0.006 0.097 -9999.0 0.0 -0.304 36.0 36.0 Nephrin/NEPH1/podocin/NCK1-2 0.037 0.085 -9999.0 0.0 -0.308 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 0.027 0.08 -9999.0 0.0 -0.279 13.0 13.0 NPHS1 -0.02 0.1 -9999.0 0.0 -0.402 25.0 25.0 Nephrin/NEPH1/podocin 0.019 0.08 -9999.0 0.0 -0.288 14.0 14.0 TJP1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.09 -9999.0 0.0 -0.314 12.0 12.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.029 0.092 -9999.0 0.0 -0.321 13.0 13.0 GRB2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.024 0.094 0.281 8.0 -0.257 34.0 42.0 cytoskeleton organization -0.007 0.064 0.209 3.0 -0.301 9.0 12.0 Nephrin/NEPH1 0.01 0.069 -9999.0 0.0 -0.21 35.0 35.0 Nephrin/NEPH1/ZO-1 0.024 0.084 -9999.0 0.0 -0.242 35.0 35.0