Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.444 0.216 0.534 55.0 -9999.0 0.0 55.0 KIRREL -0.093 0.14 -9999.0 0.0 -0.702 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.445 0.217 -9999.0 0.0 -0.535 55.0 55.0 PLCG1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.03 0.028 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.444 0.261 -9999.0 0.0 -0.52 57.0 57.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.391 0.231 -9999.0 0.0 -0.46 56.0 56.0 FYN -0.425 0.234 -9999.0 0.0 -0.49 57.0 57.0 mol:Ca2+ -0.437 0.258 -9999.0 0.0 -0.519 56.0 56.0 mol:DAG -0.44 0.26 -9999.0 0.0 -0.522 56.0 56.0 NPHS2 -0.3 0.313 -9999.0 0.0 -0.699 25.0 25.0 mol:IP3 -0.44 0.26 -9999.0 0.0 -0.522 56.0 56.0 regulation of endocytosis -0.395 0.236 -9999.0 0.0 -0.463 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.444 0.257 -9999.0 0.0 -0.518 57.0 57.0 establishment of cell polarity -0.444 0.216 -9999.0 0.0 -0.534 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.416 0.25 -9999.0 0.0 -0.489 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.401 0.242 -9999.0 0.0 -0.471 57.0 57.0 NPHS1 -0.553 0.251 -9999.0 0.0 -0.67 54.0 54.0 Nephrin/NEPH1/podocin -0.422 0.247 -9999.0 0.0 -0.494 57.0 57.0 TJP1 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.442 0.263 -9999.0 0.0 -0.525 56.0 56.0 CD2AP 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.444 0.261 -9999.0 0.0 -0.52 57.0 57.0 GRB2 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.413 0.235 -9999.0 0.0 -0.487 55.0 55.0 cytoskeleton organization -0.49 0.267 -9999.0 0.0 -0.571 56.0 56.0 Nephrin/NEPH1 -0.326 0.165 -9999.0 0.0 -0.392 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.365 0.189 -9999.0 0.0 -0.442 55.0 55.0