Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.485 0.261 0.621 392.0 -9999.0 0.0 392.0 KIRREL -0.054 0.102 -9999.0 0.0 -0.823 8.0 8.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.486 0.262 -9999.0 0.0 -0.623 392.0 392.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.039 -9999.0 0.0 -0.862 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.531 0.311 -9999.0 0.0 -0.843 219.0 219.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.41 0.262 -9999.0 0.0 -0.667 219.0 219.0 FYN -0.5 0.302 -9999.0 0.0 -0.8 219.0 219.0 mol:Ca2+ -0.523 0.306 -9999.0 0.0 -0.83 219.0 219.0 mol:DAG -0.527 0.308 -9999.0 0.0 -0.836 219.0 219.0 NPHS2 -0.412 0.383 -9999.0 0.0 -0.809 244.0 244.0 mol:IP3 -0.527 0.308 -9999.0 0.0 -0.836 219.0 219.0 regulation of endocytosis -0.47 0.279 -9999.0 0.0 -0.751 219.0 219.0 Nephrin/NEPH1/podocin/Cholesterol -0.54 0.314 -9999.0 0.0 -0.652 419.0 419.0 establishment of cell polarity -0.485 0.261 -9999.0 0.0 -0.621 392.0 392.0 Nephrin/NEPH1/podocin/NCK1-2 -0.489 0.293 -9999.0 0.0 -0.787 219.0 219.0 Nephrin/NEPH1/beta Arrestin2 -0.479 0.286 -9999.0 0.0 -0.767 219.0 219.0 NPHS1 -0.608 0.328 -9999.0 0.0 -0.786 390.0 390.0 Nephrin/NEPH1/podocin -0.508 0.298 -9999.0 0.0 -0.808 219.0 219.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.034 -9999.0 0.0 -0.747 1.0 1.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.531 0.311 -9999.0 0.0 -0.843 219.0 219.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.531 0.311 -9999.0 0.0 -0.843 219.0 219.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.489 0.301 -9999.0 0.0 -0.79 219.0 219.0 cytoskeleton organization -0.529 0.32 -9999.0 0.0 -0.85 219.0 219.0 Nephrin/NEPH1 -0.364 0.199 -9999.0 0.0 -0.466 392.0 392.0 Nephrin/NEPH1/ZO-1 -0.394 0.217 -9999.0 0.0 -0.506 392.0 392.0