Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER KARNOFSKY.PERFORMANCE.SCORE HISTOLOGICAL.TYPE NUMBERPACKYEARSSMOKED YEAROFTOBACCOSMOKINGONSET nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q 1p gain 4 (3%) 135 6.273e-11 3.59e-08 0.43661 1 0.024755 1 0.011868 1 0.039373 1 0.27741 1 0.082294 1 NA NA 1 1 NA NA NA NA 1q gain 11 (8%) 128 3.7027e-06 0.00211 0.37498 1 0.00016292 0.0912 6.8859e-05 0.0389 0.37907 1 0.1302 1 0.088146 1 NA NA 1 1 NA NA NA NA 2p gain 24 (17%) 115 0.075125 1 0.53344 1 0.067527 1 0.52167 1 0.20256 1 0.003105 1 0.46464 1 0.36184 1 0.27646 1 NA NA NA NA 2q gain 26 (19%) 113 0.15866 1 0.99763 1 0.016948 1 0.56658 1 0.1273 1 0.0050771 1 0.34686 1 0.34974 1 0.31222 1 NA NA NA NA 3p gain 39 (28%) 100 0.22615 1 0.55546 1 0.065038 1 0.027086 1 1 1 0.34521 1 0.30685 1 0.091391 1 0.67301 1 NA NA NA NA 3q gain 45 (32%) 94 0.10195 1 0.42088 1 0.10031 1 0.050571 1 1 1 0.14001 1 0.17253 1 0.28345 1 1 1 0.37919 1 NA NA 4p gain 6 (4%) 133 0.014656 1 0.0041665 1 0.070562 1 0.71562 1 0.52962 1 0.18812 1 0.66778 1 NA NA 1 1 NA NA NA NA 4q gain 5 (4%) 134 0.31075 1 0.013747 1 0.30141 1 0.65419 1 0.28432 1 0.6877 1 1 1 NA NA 1 1 NA NA NA NA 5p gain 21 (15%) 118 0.39487 1 0.63147 1 0.21634 1 0.22946 1 0.86231 1 0.40507 1 0.61016 1 0.33626 1 0.59083 1 NA NA NA NA 5q gain 20 (14%) 119 0.1159 1 0.96769 1 0.30594 1 0.33697 1 1 1 0.38505 1 0.79308 1 0.33626 1 0.59322 1 NA NA NA NA 6p gain 5 (4%) 134 0.053012 1 0.67886 1 0.042645 1 0.040701 1 0.4338 1 0.0027185 1 0.32234 1 NA NA 0.20064 1 NA NA NA NA 6q gain 3 (2%) 136 2.6983e-06 0.00154 0.25358 1 0.032346 1 0.49451 1 NA NA 0.0027343 1 0.55352 1 NA NA 0.12485 1 NA NA NA NA 7p gain 81 (58%) 58 0.092685 1 0.44527 1 0.0058146 1 0.016655 1 1 1 0.13926 1 0.1335 1 0.18925 1 0.40056 1 NA NA NA NA 7q gain 82 (59%) 57 0.083963 1 0.3763 1 0.0033027 1 0.011053 1 1 1 0.18311 1 0.091457 1 0.18925 1 0.40056 1 NA NA NA NA 8p gain 10 (7%) 129 0.03305 1 0.90915 1 0.36264 1 0.2689 1 0.44067 1 0.8461 1 0.48955 1 NA NA 1 1 NA NA NA NA 8q gain 13 (9%) 126 1.2658e-05 0.00722 0.82008 1 0.039175 1 0.033083 1 0.030472 1 0.37677 1 0.21205 1 0.50226 1 1 1 NA NA NA NA 9p gain 3 (2%) 136 0.085481 1 0.93775 1 0.085264 1 0.092267 1 NA NA 0.66305 1 1 1 NA NA 1 1 NA NA NA NA 10p gain 5 (4%) 134 0.50882 1 0.94213 1 0.23497 1 0.50442 1 NA NA 0.37262 1 1 1 NA NA 1 1 NA NA NA NA 10q gain 5 (4%) 134 0.50882 1 0.94213 1 0.23497 1 0.50442 1 NA NA 0.37262 1 1 1 NA NA 1 1 NA NA NA NA 11p gain 6 (4%) 133 0.025567 1 0.29729 1 0.042645 1 0.045736 1 0.72125 1 0.010942 1 1 1 NA NA 1 1 NA NA NA NA 11q gain 4 (3%) 135 0.76557 1 0.1259 1 0.17779 1 0.060225 1 1 1 0.1372 1 0.58416 1 NA NA 1 1 NA NA NA NA 12p gain 55 (40%) 84 0.44744 1 0.70847 1 0.74075 1 0.65634 1 0.49255 1 0.10221 1 0.091818 1 0.73627 1 0.03577 1 0.35204 1 NA NA 12q gain 55 (40%) 84 0.44744 1 0.70847 1 0.74075 1 0.65634 1 0.49255 1 0.10221 1 0.091818 1 0.73627 1 0.03577 1 0.35204 1 NA NA 13q gain 15 (11%) 124 0.49205 1 0.14465 1 0.60168 1 0.66597 1 NA NA 1 1 0.77196 1 0.18224 1 0.12661 1 NA NA NA NA 14q gain 3 (2%) 136 NA NA NA NA 0.057324 1 0.036531 1 NA NA 0.66305 1 0.21689 1 NA NA 1 1 NA NA NA NA 16p gain 72 (52%) 67 0.93703 1 0.35498 1 0.75606 1 1 1 1 1 0.2241 1 0.0054389 1 0.48754 1 0.42852 1 NA NA NA NA 16q gain 70 (50%) 69 0.27662 1 0.53711 1 0.63007 1 0.75729 1 0.8042 1 0.04484 1 0.027305 1 0.3269 1 0.44106 1 NA NA NA NA 17p gain 81 (58%) 58 0.077193 1 0.046252 1 0.00011082 0.0625 0.00043226 0.239 0.22666 1 2.3297e-05 0.0132 0.023964 1 0.24608 1 1 1 0.35204 1 NA NA 17q gain 94 (68%) 45 0.60721 1 0.10833 1 0.13682 1 0.13946 1 0.50638 1 0.00030942 0.172 0.11365 1 0.65114 1 0.66379 1 NA NA NA NA 18p gain 7 (5%) 132 0.90222 1 0.57586 1 0.46661 1 0.52929 1 NA NA 0.092391 1 1 1 0.54198 1 0.27088 1 NA NA NA NA 18q gain 5 (4%) 134 0.34503 1 0.94255 1 0.72399 1 0.65419 1 NA NA 0.46855 1 1 1 NA NA 0.20064 1 NA NA NA NA 19p gain 3 (2%) 136 0.63954 1 0.33722 1 0.53118 1 0.49451 1 1 1 0.66305 1 1 1 NA NA 1 1 NA NA NA NA 19q gain 3 (2%) 136 0.63954 1 0.33722 1 0.53118 1 0.49451 1 1 1 0.66305 1 1 1 NA NA 1 1 NA NA NA NA 20p gain 46 (33%) 93 0.9319 1 0.065496 1 0.46085 1 0.44384 1 0.87567 1 0.85335 1 1 1 0.40156 1 0.092983 1 NA NA NA NA 20q gain 48 (35%) 91 0.60408 1 0.049733 1 0.21388 1 0.24306 1 0.77103 1 0.9497 1 0.84837 1 0.40156 1 0.18168 1 NA NA NA NA 21q gain 6 (4%) 133 0.76557 1 0.026761 1 0.55098 1 0.2501 1 NA NA 0.5051 1 0.66778 1 NA NA 1 1 NA NA NA NA xq gain 41 (29%) 98 0.92682 1 0.88472 1 0.049959 1 0.043043 1 1 1 0.35268 1 0.041828 1 0.13439 1 0.67014 1 0.37919 1 NA NA 1p loss 16 (12%) 123 0.66437 1 0.97899 1 0.45164 1 0.63941 1 0.52962 1 0.56377 1 1 1 0.34061 1 1 1 NA NA NA NA 1q loss 10 (7%) 129 0.50668 1 0.38564 1 0.30436 1 0.64486 1 NA NA 0.46988 1 1 1 0.34061 1 1 1 NA NA NA NA 3p loss 11 (8%) 128 0.0096238 1 0.14713 1 0.00056547 0.312 0.00071129 0.39 0.86369 1 0.098925 1 1 1 NA NA 0.39601 1 NA NA NA NA 3q loss 4 (3%) 135 1.5443e-13 8.86e-11 0.20349 1 0.0081826 1 0.011868 1 0.16376 1 0.27741 1 0.58416 1 NA NA 0.16346 1 NA NA NA NA 4p loss 11 (8%) 128 0.16206 1 0.05195 1 0.0077777 1 0.0025042 1 0.027946 1 0.45961 1 0.0031416 1 NA NA 1 1 NA NA NA NA 4q loss 12 (9%) 127 0.76926 1 0.23096 1 0.026083 1 0.024188 1 0.26662 1 0.11426 1 0.044024 1 0.72358 1 1 1 NA NA NA NA 5p loss 5 (4%) 134 0.0011811 0.641 0.26112 1 0.043649 1 0.040701 1 0.062369 1 0.27741 1 0.16206 1 NA NA 1 1 NA NA NA NA 5q loss 5 (4%) 134 0.085481 1 0.11331 1 0.1992 1 0.040701 1 0.039373 1 0.27741 1 0.16206 1 NA NA 1 1 NA NA NA NA 6p loss 11 (8%) 128 0.0067928 1 0.40463 1 0.040431 1 0.030828 1 0.10814 1 1 1 0.088146 1 0.19321 1 1 1 NA NA NA NA 6q loss 13 (9%) 126 0.065124 1 0.9468 1 0.044466 1 0.0054366 1 0.13618 1 0.54217 1 0.021584 1 0.36305 1 1 1 NA NA NA NA 8p loss 5 (4%) 134 0.0004046 0.225 0.2048 1 0.030944 1 0.50442 1 NA NA 0.011105 1 0.16206 1 NA NA 0.20064 1 NA NA NA NA 8q loss 3 (2%) 136 0.0097379 1 0.64052 1 0.1095 1 0.21958 1 NA NA 0.1372 1 0.21689 1 NA NA 1 1 NA NA NA NA 9p loss 19 (14%) 120 0.0088355 1 0.57538 1 0.00015541 0.0872 0.00021474 0.12 0.21013 1 0.044221 1 0.0072737 1 0.36975 1 1 1 NA NA NA NA 9q loss 20 (14%) 119 0.016787 1 0.90446 1 0.0018689 1 0.00015015 0.0845 0.1273 1 0.30513 1 0.062445 1 0.38538 1 0.59322 1 NA NA NA NA 10p loss 9 (6%) 130 0.20442 1 0.63819 1 0.038385 1 0.028188 1 0.080628 1 0.099345 1 0.45322 1 0.40253 1 1 1 NA NA NA NA 10q loss 8 (6%) 131 0.15086 1 0.45633 1 0.038385 1 0.019981 1 0.080628 1 0.099345 1 0.69777 1 0.40253 1 1 1 NA NA NA NA 11p loss 10 (7%) 129 0.00028643 0.16 0.11131 1 0.057572 1 0.10935 1 0.16376 1 0.59352 1 0.16923 1 NA NA 0.36655 1 NA NA NA NA 11q loss 13 (9%) 126 1.3063e-05 0.00743 0.066602 1 0.00056021 0.309 0.00041876 0.232 0.058478 1 0.18013 1 0.53247 1 0.34061 1 0.45152 1 NA NA NA NA 13q loss 12 (9%) 127 0.00076422 0.418 0.21641 1 0.014685 1 0.011752 1 0.030472 1 0.41534 1 0.0010958 0.596 0.34061 1 1 1 NA NA NA NA 14q loss 27 (19%) 112 0.2061 1 0.86106 1 0.0098791 1 0.089342 1 0.10518 1 0.13391 1 0.24256 1 0.35635 1 1 1 NA NA NA NA 15q loss 15 (11%) 124 0.00015416 0.0866 0.13494 1 0.076554 1 0.025996 1 0.21669 1 0.081431 1 0.38521 1 0.72358 1 1 1 NA NA NA NA 16p loss 4 (3%) 135 1.5068e-05 0.00856 0.66272 1 0.1992 1 0.14496 1 NA NA 1 1 0.082294 1 NA NA 1 1 NA NA NA NA 16q loss 4 (3%) 135 1.5068e-05 0.00856 0.66272 1 0.1992 1 0.14496 1 NA NA 1 1 0.082294 1 NA NA 1 1 NA NA NA NA 17p loss 8 (6%) 131 2.2204e-16 1.28e-13 0.73127 1 0.00076773 0.419 0.012458 1 0.0079128 1 0.040827 1 0.054201 1 0.47215 1 1 1 NA NA NA NA 18p loss 22 (16%) 117 0.0096747 1 0.51099 1 0.0045394 1 0.001317 0.714 0.1273 1 0.082052 1 0.61321 1 0.76534 1 1 1 NA NA NA NA 18q loss 23 (17%) 116 0.0096747 1 0.51099 1 0.0019591 1 0.00064046 0.352 0.1273 1 0.075124 1 0.32705 1 0.76534 1 1 1 NA NA NA NA 19p loss 9 (6%) 130 0.22394 1 0.60565 1 0.085843 1 0.028188 1 0.17108 1 0.60608 1 0.45322 1 0.74147 1 1 1 NA NA NA NA 19q loss 8 (6%) 131 0.10938 1 0.909 1 0.035168 1 0.0076614 1 0.17108 1 0.41294 1 0.2433 1 0.74147 1 1 1 NA NA NA NA 21q loss 27 (19%) 112 0.97887 1 0.69517 1 0.0081706 1 0.0068643 1 0.37907 1 0.13614 1 0.24256 1 0.8915 1 1 1 0.40781 1 NA NA 22q loss 34 (24%) 105 0.36956 1 0.62928 1 0.00065792 0.361 0.00036314 0.202 0.14691 1 0.23678 1 0.018352 1 0.43309 1 1 1 NA NA NA NA xq loss 16 (12%) 123 0.0010817 0.59 0.29138 1 0.019364 1 0.0042007 1 0.08233 1 0.17883 1 0.084178 1 0.4775 1 0.14178 1 NA NA NA NA