		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	5 (3%)	167	0.00043583	0.198	0.0026677	1	0.02935	1	0.046683	1	0.23627	1	0.041158	1	0.23274	1	0.26394	1
1q gain	14 (8%)	158	3.5901e-06	0.00181	1.1371e-06	0.000578	6.2751e-05	0.0301	0.0013197	0.575	0.23527	1	5.1174e-05	0.0247	0.38346	1	0.026246	1
2p gain	32 (19%)	140	7.4383e-08	3.95e-05	0.012321	1	0.18122	1	0.75517	1	0.11396	1	0.70579	1	0.045147	1	0.8011	1
2q gain	35 (20%)	137	2.6693e-09	1.44e-06	0.026165	1	0.52918	1	0.65325	1	0.14502	1	1	1	0.039811	1	0.94102	1
3p gain	46 (27%)	126	5.7952e-19	3.19e-16	0.024359	1	6.6845e-05	0.032	0.082005	1	0.15966	1	0.0033977	1	0.31797	1	0.015178	1
3q gain	55 (32%)	117	1.6443e-17	8.99e-15	0.03425	1	2.2918e-05	0.0113	0.087565	1	0.13199	1	0.021975	1	0.43452	1	0.020817	1
4p gain	6 (3%)	166	0.88512	1	0.16224	1	0.93704	1	0.87009	1	1	1	0.19647	1	0.59307	1	0.039981	1
4q gain	5 (3%)	167	1	1	0.16224	1	1	1	0.51993	1	0.73898	1	0.63926	1	0.44957	1	0.19249	1
5p gain	26 (15%)	146	0.00088953	0.392	0.0014383	0.624	0.10619	1	0.00061658	0.277	0.068523	1	0.097156	1	0.23495	1	0.3048	1
5q gain	26 (15%)	146	0.0022612	0.963	0.0081053	1	0.10703	1	0.00061658	0.277	0.068523	1	0.29666	1	0.23495	1	0.36809	1
6p gain	8 (5%)	164	0.16653	1	0.045916	1	0.036435	1	0.24449	1	0.029795	1	0.10412	1	0.0094105	1	0.29102	1
6q gain	6 (3%)	166	0.044223	1	0.041316	1	0.17225	1	0.37342	1	0.16518	1	0.24679	1	0.064951	1	0.42564	1
7p gain	100 (58%)	72	5.4728e-19	3.02e-16	7.5533e-08	4e-05	3.5472e-13	1.93e-10	1.3796e-07	7.23e-05	0.099048	1	0.00023924	0.11	0.16735	1	0.010417	1
7q gain	101 (59%)	71	1.8689e-18	1.03e-15	2.1166e-07	0.00011	4.8755e-13	2.65e-10	2.0141e-07	0.000105	0.14055	1	0.001264	0.554	0.22155	1	0.040792	1
8p gain	12 (7%)	160	0.141	1	0.0028905	1	0.13396	1	0.85932	1	0.10774	1	0.054361	1	0.31226	1	0.032066	1
8q gain	15 (9%)	157	0.039986	1	2.4524e-05	0.012	0.0047239	1	0.21384	1	0.0074334	1	0.013503	1	0.068318	1	0.00495	1
9p gain	3 (2%)	169	0.69657	1	NA	NA	0.26069	1	0.095138	1	0.77502	1	0.087594	1	0.77677	1	0.059438	1
10p gain	5 (3%)	167	0.049388	1	0.03977	1	0.65053	1	1	1	0.16309	1	0.41046	1	0.13031	1	0.353	1
10q gain	5 (3%)	167	0.049388	1	0.03977	1	0.65053	1	1	1	0.16309	1	0.41046	1	0.13031	1	0.353	1
11p gain	8 (5%)	164	0.015309	1	0.0015128	0.654	0.65733	1	0.012371	1	0.077484	1	0.35834	1	1	1	0.24868	1
11q gain	7 (4%)	165	0.0099577	1	0.00067135	0.3	0.5129	1	0.034692	1	0.17747	1	0.8687	1	1	1	0.58759	1
12p gain	68 (40%)	104	0.00023579	0.109	0.46109	1	0.015568	1	0.13096	1	0.2884	1	0.068955	1	0.059707	1	0.20867	1
12q gain	68 (40%)	104	0.00023579	0.109	0.46109	1	0.015568	1	0.13096	1	0.2884	1	0.068955	1	0.059707	1	0.20867	1
13q gain	19 (11%)	153	0.046748	1	1	1	0.31794	1	0.72242	1	1	1	1	1	0.92267	1	1	1
14q gain	3 (2%)	169	0.25757	1	0.03977	1	0.55661	1	0.095138	1	1	1	0.087594	1	1	1	0.059438	1
15q gain	5 (3%)	167	0.01735	1	0.041316	1	0.29896	1	0.07313	1	0.52681	1	0.63926	1	0.73582	1	0.353	1
16p gain	89 (52%)	83	3.337e-10	1.8e-07	0.24159	1	0.00052764	0.239	0.00060018	0.27	0.038363	1	0.023219	1	0.0030467	1	0.016973	1
16q gain	85 (49%)	87	2.8832e-11	1.56e-08	0.089588	1	5.2763e-05	0.0254	0.0025735	1	0.0089705	1	0.001496	0.648	0.0017551	0.753	0.0031346	1
17p gain	102 (59%)	70	1.4094e-17	7.72e-15	1.1346e-07	5.98e-05	1.3527e-10	7.3e-08	3.8419e-09	2.06e-06	0.02277	1	0.00025935	0.119	0.14417	1	0.0079088	1
17q gain	117 (68%)	55	5.2039e-12	2.83e-09	0.0011727	0.515	9.37e-07	0.000478	1.0893e-05	0.00542	0.29264	1	0.07427	1	0.49015	1	0.12194	1
18p gain	9 (5%)	163	0.17039	1	0.42304	1	0.71394	1	0.91101	1	0.13758	1	0.043234	1	0.35845	1	0.21028	1
18q gain	5 (3%)	167	0.15101	1	0.2531	1	0.52747	1	1	1	0.62348	1	0.23905	1	0.62747	1	1	1
19p gain	3 (2%)	169	0.25757	1	0.4568	1	0.55661	1	0.41216	1	0.52541	1	0.014565	1	0.5097	1	0.29464	1
19q gain	3 (2%)	169	0.25757	1	0.4568	1	0.55661	1	0.41216	1	0.52541	1	0.014565	1	0.5097	1	0.29464	1
20p gain	58 (34%)	114	0.0012694	0.555	0.10814	1	0.077732	1	0.323	1	0.3013	1	0.64639	1	0.87898	1	0.7584	1
20q gain	60 (35%)	112	0.0055071	1	0.10866	1	0.14196	1	0.45228	1	0.27577	1	0.72928	1	0.79958	1	0.74692	1
21q gain	12 (7%)	160	1	1	0.41259	1	0.052306	1	0.10154	1	0.39301	1	0.51552	1	0.22742	1	0.33742	1
xq gain	54 (31%)	118	1.511e-14	8.25e-12	0.0063954	1	6.9645e-06	0.00349	7.7525e-05	0.037	0.0080466	1	0.0076693	1	0.013161	1	0.13595	1
1p loss	21 (12%)	151	0.00012148	0.0569	0.054714	1	0.0022672	0.964	0.0035605	1	1	1	0.68987	1	0.95344	1	0.89697	1
1q loss	13 (8%)	159	0.046713	1	0.47147	1	0.63193	1	0.0045483	1	0.87746	1	0.21005	1	0.51615	1	0.36584	1
3p loss	14 (8%)	158	1.6119e-05	0.00798	4.4728e-07	0.00023	0.00031393	0.143	0.0010792	0.475	0.011366	1	0.0033353	1	0.41493	1	0.0001041	0.049
3q loss	4 (2%)	168	0.0024794	1	0.010397	1	0.1167	1	0.022838	1	0.32787	1	0.5849	1	0.38759	1	0.056445	1
4p loss	18 (10%)	154	2.6912e-07	0.00014	1.0248e-07	5.42e-05	3.5686e-07	0.000184	7.8003e-06	0.0039	0.43594	1	0.06532	1	0.665	1	0.025528	1
4q loss	19 (11%)	153	7.2279e-08	3.86e-05	2.5735e-08	1.38e-05	1.2653e-07	6.64e-05	2.7612e-05	0.0135	0.59944	1	0.12364	1	0.58154	1	0.042574	1
5p loss	7 (4%)	165	0.32185	1	0.0015128	0.654	0.014859	1	3.3447e-05	0.0163	0.01854	1	0.088473	1	0.030876	1	0.06495	1
5q loss	7 (4%)	165	0.32185	1	0.0015128	0.654	0.014859	1	3.3447e-05	0.0163	0.01854	1	0.088473	1	0.030876	1	0.06495	1
6p loss	12 (7%)	160	0.006604	1	0.041867	1	0.045288	1	0.014218	1	0.49025	1	0.39862	1	0.86892	1	0.33742	1
6q loss	15 (9%)	157	9.9164e-05	0.0468	0.00087105	0.386	0.010683	1	0.032552	1	0.56714	1	0.54823	1	0.70299	1	0.2597	1
8p loss	6 (3%)	166	0.044223	1	1	1	0.60767	1	0.41925	1	0.37352	1	0.19647	1	0.37951	1	0.11752	1
8q loss	4 (2%)	168	0.093147	1	1	1	0.42097	1	0.095138	1	1	1	0.43761	1	1	1	0.38099	1
9p loss	22 (13%)	150	1.6916e-06	0.000858	3.9882e-07	0.000206	9.8924e-07	0.000504	0.00018687	0.0863	0.022189	1	0.0094516	1	0.064132	1	0.012143	1
9q loss	24 (14%)	148	3.0303e-06	0.00153	1.5255e-07	7.98e-05	1.1508e-07	6.05e-05	5.4112e-07	0.000278	0.0055062	1	6.0347e-05	0.029	0.034683	1	9.5827e-05	0.0453
10p loss	12 (7%)	160	7.3149e-08	3.9e-05	7.4924e-05	0.0358	0.00074582	0.333	0.16424	1	0.2893	1	0.00011404	0.0535	0.33744	1	0.00055771	0.252
10q loss	12 (7%)	160	3.0452e-06	0.00153	1.9127e-05	0.00943	0.00074582	0.333	0.02755	1	0.060693	1	1.4247e-05	0.00707	0.086918	1	0.00013871	0.0648
11p loss	10 (6%)	162	0.00083622	0.371	0.0038864	1	0.014573	1	0.027827	1	0.084578	1	0.17239	1	0.42833	1	0.013461	1
11q loss	14 (8%)	158	1.6119e-05	0.00798	0.0001481	0.069	0.022392	1	0.018254	1	0.070608	1	0.070965	1	0.41493	1	0.026246	1
13q loss	17 (10%)	155	1.2118e-05	0.00602	1.4248e-08	7.64e-06	7.8355e-06	0.00391	7.8153e-05	0.0372	0.010745	1	0.0020978	0.896	0.05996	1	0.0062666	1
14q loss	34 (20%)	138	1.1243e-11	6.09e-09	0.0043848	1	0.00026688	0.122	8.2055e-07	0.000419	0.075498	1	0.0043554	1	0.26809	1	0.14952	1
15q loss	19 (11%)	153	9.3318e-05	0.0442	0.00407	1	0.011919	1	1.1063e-07	5.84e-05	0.14037	1	0.42256	1	0.14439	1	0.16016	1
16p loss	4 (2%)	168	0.093147	1	0.010397	1	0.1167	1	0.022838	1	1	1	0.5849	1	1	1	0.056445	1
16q loss	5 (3%)	167	0.01735	1	0.0026677	1	0.02935	1	0.046683	1	0.62348	1	0.31796	1	0.62747	1	0.0083482	1
17p loss	8 (5%)	164	0.015309	1	0.0001656	0.077	0.0017774	0.761	0.0033621	1	0.28423	1	0.072959	1	0.31234	1	0.039622	1
18p loss	28 (16%)	144	0.00033659	0.153	3.9153e-06	0.00197	2.0301e-06	0.00103	0.00059806	0.27	0.047229	1	0.11274	1	0.32389	1	0.34767	1
18q loss	30 (17%)	142	3.3034e-05	0.0161	2.9694e-07	0.000154	2.5968e-07	0.000135	0.00017682	0.0819	0.065354	1	0.13285	1	0.33018	1	0.23977	1
19p loss	12 (7%)	160	0.00087422	0.386	0.01071	1	0.11104	1	0.032947	1	0.0284	1	0.052137	1	0.56588	1	0.018223	1
19q loss	11 (6%)	161	8.492e-05	0.0403	0.041867	1	0.091982	1	0.14733	1	0.039096	1	0.11655	1	0.28585	1	0.051035	1
21q loss	30 (17%)	142	0.00017278	0.0802	0.18757	1	0.66825	1	0.071988	1	0.68632	1	0.19087	1	0.28363	1	0.75828	1
22q loss	41 (24%)	131	6.8755e-07	0.000352	4.7309e-07	0.000243	7.3693e-08	3.92e-05	0.0013464	0.586	0.1355	1	0.00010989	0.0516	0.046448	1	0.076441	1
xq loss	20 (12%)	152	2.2632e-05	0.0111	4.3517e-05	0.0211	3.0779e-05	0.015	0.033708	1	0.19751	1	0.054639	1	0.2649	1	0.012072	1
