Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.095 0.225 -9999.0 0.0 -0.461 81.0 81.0 MAP3K8 -0.001 0.083 -9999.0 0.0 -0.494 10.0 10.0 FOS -0.087 0.202 -9999.0 0.0 -0.497 58.0 58.0 PRKCA 0.011 0.033 -9999.0 0.0 -0.604 1.0 1.0 PTPN7 -0.126 0.244 -9999.0 0.0 -0.546 91.0 91.0 HRAS 0.013 0.026 -9999.0 0.0 -0.48 1.0 1.0 PRKCB -0.064 0.188 -9999.0 0.0 -0.517 53.0 53.0 NRAS 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.023 -9999.0 0.0 -0.245 2.0 2.0 MAPK3 -0.071 0.176 -9999.0 0.0 -0.463 53.0 53.0 MAP2K1 -0.015 0.132 -9999.0 0.0 -0.494 16.0 16.0 ELK1 0.013 0.006 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.055 0.141 -9999.0 0.0 -0.46 30.0 30.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 62.0 62.0 MAPK1 -0.071 0.176 -9999.0 0.0 -0.463 53.0 53.0 RAF1 -0.037 0.105 -9999.0 0.0 -0.466 15.0 15.0 KRAS 0.013 0.026 -9999.0 0.0 -0.48 1.0 1.0