Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.005 0.098 0.318 29.0 -9999.0 0.0 29.0 KIRREL -0.01 0.121 -9999.0 0.0 -0.434 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.004 0.098 -9999.0 0.0 -0.319 29.0 29.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.02 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.027 0.083 -9999.0 0.0 -0.237 29.0 29.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.005 0.073 -9999.0 0.0 -0.248 25.0 25.0 FYN -0.011 0.078 0.27 5.0 -0.226 30.0 35.0 mol:Ca2+ 0.024 0.083 -9999.0 0.0 -0.235 30.0 30.0 mol:DAG 0.025 0.084 -9999.0 0.0 -0.236 30.0 30.0 NPHS2 -0.0 0.035 -9999.0 0.0 -0.277 2.0 2.0 mol:IP3 0.025 0.084 -9999.0 0.0 -0.236 30.0 30.0 regulation of endocytosis 0.021 0.075 -9999.0 0.0 -0.214 30.0 30.0 Nephrin/NEPH1/podocin/Cholesterol 0.014 0.078 -9999.0 0.0 -0.235 30.0 30.0 establishment of cell polarity -0.005 0.098 -9999.0 0.0 -0.318 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 0.037 0.085 -9999.0 0.0 -0.225 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 0.023 0.076 -9999.0 0.0 -0.216 30.0 30.0 NPHS1 -0.003 0.062 -9999.0 0.0 -0.319 7.0 7.0 Nephrin/NEPH1/podocin 0.015 0.076 -9999.0 0.0 -0.227 30.0 30.0 TJP1 0.026 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.024 0.024 -9999.0 0.0 -0.429 1.0 1.0 NCK2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.026 0.084 -9999.0 0.0 -0.237 30.0 30.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.026 0.083 -9999.0 0.0 -0.237 29.0 29.0 GRB2 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.015 0.087 0.24 9.0 -0.226 37.0 46.0 cytoskeleton organization -0.02 0.086 0.205 7.0 -0.274 25.0 32.0 Nephrin/NEPH1 0.008 0.069 -9999.0 0.0 -0.218 29.0 29.0 Nephrin/NEPH1/ZO-1 0.02 0.084 -9999.0 0.0 -0.252 29.0 29.0