Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.038 0.205 -9999.0 0.0 -0.472 50.0 50.0 MAP3K8 0.019 0.032 -9999.0 0.0 -0.433 1.0 1.0 FOS -0.039 0.182 -9999.0 0.0 -0.447 51.0 51.0 PRKCA 0.021 0.027 -9999.0 0.0 -0.43 1.0 1.0 PTPN7 -0.052 0.152 -9999.0 0.0 -0.425 47.0 47.0 HRAS 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.009 0.095 -9999.0 0.0 -0.34 20.0 20.0 NRAS 0.021 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.034 0.025 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.03 0.161 -9999.0 0.0 -0.427 47.0 47.0 MAP2K1 0.005 0.11 -9999.0 0.0 -0.499 12.0 12.0 ELK1 0.022 0.015 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.009 0.1 -9999.0 0.0 -0.409 18.0 18.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 36.0 36.0 MAPK1 -0.036 0.17 -9999.0 0.0 -0.433 50.0 50.0 RAF1 -0.001 0.091 -9999.0 0.0 -0.446 13.0 13.0 KRAS 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0