Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q CDKN2A 26 (15%) 151 0.0017733 0.323 0.062654 1 0.018341 1 0.66826 1 0.33991 1 0.20268 1 0.33053 1 0.64614 1 0.75139 1 1 1 1 1 0.099321 1 TP53 141 (80%) 36 0.084591 1 0.052449 1 0.0001805 0.0338 0.0015311 0.28 1 1 0.89382 1 0.0021005 0.378 0.018284 1 0.11853 1 0.56457 1 0.82375 1 0.72649 1 NFE2L2 27 (15%) 150 0.00035642 0.0663 0.0011452 0.211 0.018498 1 0.033387 1 0.26111 1 0.14936 1 6.2646e-06 0.00118 2.4586e-06 0.000465 0.029552 1 2.3631e-06 0.000449 0.58927 1 0.14 1 PIK3CA 27 (15%) 150 0.6396 1 0.57762 1 0.44832 1 0.54503 1 1 1 0.7024 1 0.39008 1 0.91634 1 0.61508 1 0.67135 1 0.45639 1 0.72649 1 PTEN 14 (8%) 163 0.37597 1 0.42658 1 0.43879 1 0.13405 1 0.72126 1 0.4734 1 0.61279 1 0.15796 1 0.57491 1 0.43107 1 0.35718 1 1 1 KEAP1 22 (12%) 155 0.0019553 0.354 0.00040319 0.0746 0.17025 1 0.075772 1 0.20419 1 0.096341 1 0.15873 1 0.042775 1 0.70078 1 0.82396 1 0.005042 0.903 0.60984 1 MLL2 35 (20%) 142 0.14557 1 0.80881 1 0.25292 1 0.31509 1 0.69613 1 0.22053 1 0.24777 1 0.61065 1 0.94796 1 0.6384 1 0.61383 1 1 1 CSMD3 81 (46%) 96 0.23976 1 0.87797 1 0.74606 1 0.47909 1 0.27527 1 0.76473 1 0.4294 1 0.76877 1 0.64213 1 1 1 0.38949 1 0.16371 1 RB1 12 (7%) 165 0.3431 1 0.19801 1 0.41753 1 0.10805 1 0.6571 1 0.43325 1 1 1 0.35481 1 0.57491 1 0.91122 1 NA NA 1 1 HS6ST1 5 (3%) 172 0.26873 1 0.29526 1 0.52967 1 NA NA NA NA NA NA 0.5678 1 0.10087 1 1 1 1 1 NA NA NA NA FBXW7 10 (6%) 167 0.45776 1 1 1 0.50751 1 NA NA 0.62139 1 0.78456 1 0.83375 1 0.57449 1 0.93548 1 0.77194 1 NA NA 1 1 ZNF567 3 (2%) 174 NA NA NA NA 0.36445 1 NA NA 0.35868 1 0.42365 1 0.38906 1 0.42724 1 0.25293 1 0.19042 1 NA NA 1 1 ELTD1 18 (10%) 159 0.029518 1 0.30292 1 0.053286 1 0.5997 1 0.34058 1 0.6478 1 0.55419 1 0.4199 1 0.08865 1 0.72169 1 0.30453 1 0.41892 1 ASCL4 6 (3%) 171 0.092379 1 0.53365 1 0.88162 1 0.78258 1 0.81655 1 0.83545 1 0.34789 1 0.24731 1 0.90954 1 0.21909 1 NA NA NA NA OR2G6 16 (9%) 161 0.36643 1 0.21058 1 0.90932 1 1 1 1 1 0.71709 1 0.19889 1 0.04661 1 0.42772 1 0.24518 1 0.66839 1 0.60984 1 HLA-A 6 (3%) 171 0.039115 1 0.32963 1 0.44561 1 0.1778 1 1 1 0.51305 1 0.12821 1 0.1141 1 0.47103 1 0.72982 1 0.381 1 1 1 NOTCH1 14 (8%) 163 0.81203 1 0.92079 1 0.54324 1 0.034203 1 0.59052 1 0.82385 1 0.68576 1 0.40102 1 0.18508 1 0.84421 1 0.4831 1 0.66795 1