Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER HISTOLOGICAL.TYPE NUMBERPACKYEARSSMOKED YEAROFTOBACCOSMOKINGONSET COMPLETENESS.OF.RESECTION NUMBER.OF.LYMPH.NODES nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q C15ORF24 6 (14%) 38 0.9082 1 0.28141 1 0.080998 1 0.45625 1 0.11966 1 0.55441 1 0.02114 1 1 1 NA NA NA NA 0.070248 1 0.50852 1 IRS1 4 (9%) 40 0.41787 1 0.0080617 1 0.42201 1 1 1 1 1 0.26505 1 1 1 1 1 NA NA NA NA 0.61163 1 0.5684 1 FYN 5 (11%) 39 0 0 0.73076 1 0.035354 1 0.3941 1 0.31675 1 0.047241 1 0.34487 1 1 1 NA NA NA NA 0.048204 1 0.090888 1 FADS2 5 (11%) 39 0.62691 1 0.78886 1 7.363e-05 0.0754 0.057495 1 0.0068066 1 1 1 0.34487 1 1 1 NA NA NA NA 0.17778 1 0.097408 1 C14ORF49 8 (18%) 36 0.58381 1 0.33173 1 0.6136 1 0.56608 1 0.65852 1 0.80003 1 0.24044 1 1 1 NA NA NA NA 0.18182 1 0.16605 1 FGF10 6 (14%) 38 0.60662 1 0.62613 1 0.07793 1 0.45625 1 0.60582 1 0.7513 1 0.66403 1 1 1 NA NA NA NA 0.54705 1 0.54062 1 CEL 4 (9%) 40 0.00060353 0.617 0.46841 1 0.0054677 1 0.32678 1 0.031602 1 0.4498 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 6.3476e-06 0.00651 CCR3 5 (11%) 39 0.99705 1 0.87513 1 0.94882 1 1 1 1 1 1 1 1 1 1 1 NA NA NA NA 1 1 0.74211 1 OR10A2 6 (14%) 38 0.70655 1 0.3517 1 0.58876 1 0.45625 1 1 1 0.7513 1 0.66403 1 1 1 NA NA NA NA 0.54705 1 0.13907 1 OR10A7 9 (20%) 35 0.43059 1 0.87676 1 0.023294 1 0.18037 1 0.17477 1 0.82003 1 0.13239 1 1 1 NA NA NA NA 0.1562 1 0.61211 1 POP5 5 (11%) 39 0.34353 1 0.52178 1 0.035354 1 0.3941 1 0.31675 1 0.35337 1 0.34487 1 1 1 NA NA NA NA 0.17778 1 0.69615 1 SRP14 7 (16%) 37 0.60204 1 0.2901 1 0.93233 1 1 1 1 1 1 1 1 1 1 1 NA NA NA NA 0.36429 1 0.84111 1 WRN 4 (9%) 40 0.9082 1 0.38689 1 0.35394 1 0.32678 1 0.21757 1 1 1 0.10777 1 1 1 NA NA NA NA 0.30621 1 0.91621 1 TMEM40 8 (18%) 36 0.53989 1 0.75209 1 0.6136 1 0.56608 1 0.65852 1 0.80003 1 0.69808 1 1 1 NA NA NA NA 0.78495 1 0.45808 1 KRAS 23 (52%) 21 0.3512 1 0.73112 1 0.48311 1 0.33466 1 0.15549 1 0.67375 1 1 1 0.41038 1 0.25131 1 0.98125 1 0.65313 1 0.46464 1 TP53 27 (61%) 17 0.31999 1 0.34046 1 0.46393 1 0.6337 1 0.4727 1 0.72785 1 1 1 0.73138 1 0.60429 1 0.68624 1 0.016919 1 0.4406 1 QRICH1 7 (16%) 37 0.74277 1 0.95345 1 0.93233 1 1 1 1 1 0.78239 1 1 1 0.52269 1 0.18105 1 0.02405 1 0.048204 1 0.56824 1 ST6GALNAC5 5 (11%) 39 0.79749 1 0.51727 1 0.86544 1 1 1 0.57297 1 0.73057 1 1 1 1 1 NA NA NA NA 0.30621 1 0.64577 1 TNFSF9 6 (14%) 38 0.66425 1 0.06668 1 0.55482 1 1 1 0.60582 1 0.55441 1 0.66403 1 1 1 NA NA NA NA 0.22694 1 0.073657 1 CDKN2A 10 (23%) 34 0.15474 1 0.36841 1 0.50519 1 1 1 0.085332 1 0.83545 1 0.72051 1 1 1 0.13906 1 0.47887 1 0.1909 1 0.062559 1 SEH1L 8 (18%) 36 0.9927 1 0.21158 1 0.81196 1 0.56608 1 1 1 0.80003 1 0.69808 1 1 1 NA NA NA NA 0.024408 1 0.79397 1 SCD 8 (18%) 36 0.99675 1 0.483 1 0.010394 1 0.14531 1 0.064147 1 0.80003 1 0.69808 1 1 1 NA NA NA NA 0.032106 1 0.13892 1 TMC4 7 (16%) 37 0.9755 1 0.438 1 0.93233 1 1 1 1 1 1 1 1 1 1 1 NA NA NA NA 0.22694 1 0.57772 1 MED15 9 (20%) 35 0.92228 1 0.65809 1 0.64157 1 1 1 0.40242 1 1 1 0.45655 1 1 1 NA NA NA NA 0.1562 1 0.067984 1 TNFRSF9 6 (14%) 38 0.78448 1 0.25411 1 0.94644 1 1 1 1 1 0.7513 1 1 1 1 1 NA NA NA NA 0.54705 1 0.49411 1 BRDT 8 (18%) 36 0.42224 1 0.23032 1 0.90745 1 1 1 0.65852 1 0.31763 1 1 1 1 1 NA NA NA NA 0.64579 1 0.37773 1 CXXC4 4 (9%) 40 0.23271 1 0.55486 1 0.93286 1 1 1 1 1 0.4498 1 1 1 0.33351 1 0.50159 1 NA NA NA NA 0.17285 1 MBD3 6 (14%) 38 0.76183 1 0.63337 1 0.94644 1 1 1 1 1 0.31296 1 1 1 1 1 NA NA NA NA 1 1 0.40867 1 TULP1 6 (14%) 38 0.81169 1 0.31457 1 0.018274 1 0.45625 1 0.017933 1 1 1 0.18528 1 1 1 NA NA NA NA 0.10018 1 0.22676 1 PHF13 4 (9%) 40 0.91916 1 0.82118 1 0.93286 1 1 1 1 1 1 1 0.60692 1 0.33351 1 0.8553 1 NA NA 1 1 0.85014 1 BHLHB9 4 (9%) 40 0.019106 1 0.17271 1 0.42201 1 1 1 1 1 0.26505 1 1 1 1 1 NA NA NA NA 0.029782 1 0.63227 1 PRDM8 6 (14%) 38 0.62974 1 0.47867 1 0.94644 1 1 1 1 1 0.7513 1 1 1 1 1 NA NA NA NA 0.10018 1 0.21157 1 SMAD4 7 (16%) 37 0.64772 1 0.90232 1 0.76578 1 1 1 1 1 0.27202 1 1 1 1 1 0.69409 1 0.14921 1 1 1 0.79845 1 C14ORF43 7 (16%) 37 0.14792 1 0.37356 1 0.070851 1 0.51348 1 0.32228 1 0.27202 1 1 1 1 1 NA NA NA NA 0.19256 1 0.18257 1 MEPCE 7 (16%) 37 0.79353 1 0.6802 1 0.76578 1 0.51348 1 0.64904 1 0.58768 1 0.41206 1 1 1 NA NA NA NA 0.065464 1 0.22409 1 HVCN1 4 (9%) 40 0.22181 1 0.75336 1 0.0054677 1 0.32678 1 0.031602 1 1 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 0.0029514 1 FOXP2 7 (16%) 37 0.54665 1 0.38457 1 0.76578 1 0.51348 1 0.64904 1 1 1 1 1 1 1 NA NA NA NA 0.78495 1 0.83703 1 GRIN1 5 (11%) 39 0.54433 1 0.63122 1 0.029228 1 0.3941 1 0.068795 1 0.73057 1 1 1 1 1 NA NA NA NA 0.17778 1 0.0092194 1 MAGEA10 4 (9%) 40 0.58271 1 0.15469 1 0.05138 1 1 1 1 1 1 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 0.83564 1 C16ORF79 4 (9%) 40 0.36027 1 0.95705 1 0.35394 1 0.32678 1 0.21757 1 1 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 0.14581 1 ERF 6 (14%) 38 0.35709 1 0.82541 1 0.58876 1 0.45625 1 1 1 1 1 1 1 1 1 NA NA NA NA 1 1 0.92966 1 IFNGR2 4 (9%) 40 0.41741 1 0.54366 1 0.91688 1 1 1 0.55919 1 0.67669 1 1 1 1 1 NA NA NA NA 0.20128 1 0.29162 1 OLIG3 5 (11%) 39 0.6732 1 0.73684 1 0.41475 1 1 1 0.31675 1 1 1 1 1 1 1 NA NA NA NA 0.71641 1 0.21638 1 NDEL1 4 (9%) 40 0.22181 1 0.45617 1 0.040912 1 1 1 0.21757 1 1 1 1 1 1 1 NA NA NA NA 0.30621 1 0.0046118 1 EGR1 8 (18%) 36 0.62045 1 0.72545 1 0.81196 1 0.56608 1 1 1 0.31763 1 0.69808 1 1 1 NA NA NA NA 0.64579 1 0.5414 1 CDH3 4 (9%) 40 0.28798 1 0.26313 1 0.93286 1 1 1 1 1 1 1 0.60692 1 1 1 NA NA NA NA 1 1 0.63227 1 PCDHAC2 7 (16%) 37 0.90807 1 0.56132 1 0.76578 1 1 1 1 1 0.27202 1 1 1 1 1 NA NA NA NA 1 1 0.84111 1 ZFP36 4 (9%) 40 0.0054543 1 0.64879 1 0.91688 1 1 1 0.55919 1 0.4498 1 0.60692 1 1 1 NA NA NA NA 1 1 0.22469 1 NR4A3 5 (11%) 39 0.77481 1 0.54132 1 0.035354 1 1 1 0.31675 1 0.25523 1 1 1 1 1 NA NA NA NA 0.71641 1 0.10887 1 RAB11FIP5 5 (11%) 39 0.41101 1 0.83345 1 0.5299 1 0.3941 1 1 1 0.73057 1 1 1 1 1 NA NA NA NA 0.71641 1 0.96105 1 OTUD4 7 (16%) 37 0.59405 1 0.77564 1 0.27736 1 1 1 0.64904 1 1 1 1 1 1 1 NA NA NA NA 0.36429 1 0.15626 1 PPARGC1B 6 (14%) 38 0.55207 1 0.5782 1 0.19528 1 1 1 0.60582 1 0.55441 1 1 1 1 1 NA NA NA NA 0.17778 1 0.86964 1 PDZD2 9 (20%) 35 0.28785 1 0.67948 1 0.3935 1 0.56608 1 1 1 0.20384 1 1 1 1 1 NA NA NA NA 0.27158 1 0.86058 1 MED9 3 (7%) 41 0.33745 1 0.031239 1 0.25562 1 0.254 1 0.54817 1 1 1 1 1 1 1 NA NA NA NA 1 1 0.76981 1 BCL2L1 3 (7%) 41 0.50226 1 0.065058 1 0.079619 1 1 1 0.12458 1 0.65116 1 1 1 1 1 NA NA NA NA 0.37523 1 0.32633 1 CPLX3 3 (7%) 41 0.68385 1 0.56682 1 0.95645 1 1 1 1 1 0.65116 1 1 1 1 1 NA NA NA NA 0.37523 1 0.79452 1 NFAT5 8 (18%) 36 0.23745 1 0.14644 1 0.040202 1 0.14531 1 0.064147 1 0.80003 1 1 1 0.25752 1 NA NA NA NA 0.18182 1 0.52603 1 WASF3 5 (11%) 39 0.444 1 0.87061 1 0.54706 1 0.3941 1 0.31675 1 0.73057 1 1 1 1 1 NA NA NA NA 0.71641 1 0.93254 1 ABCC2 5 (11%) 39 0.94474 1 0.31997 1 0.5299 1 0.057495 1 1 1 0.73057 1 0.34487 1 1 1 NA NA NA NA 0.71641 1 0.1268 1 ATP13A3 4 (9%) 40 0.97239 1 0.83838 1 0.42201 1 0.32678 1 1 1 1 1 0.60692 1 1 1 NA NA NA NA 1 1 0.61054 1 ARHGAP18 4 (9%) 40 0.79749 1 0.09821 1 0.05138 1 1 1 1 1 1 1 0.10777 1 1 1 NA NA NA NA 1 1 0.9085 1 CIR1 3 (7%) 41 0.89253 1 0.95195 1 0.8713 1 1 1 0.54817 1 1 1 0.23256 1 1 1 NA NA NA NA 1 1 0.47207 1 KIAA0020 4 (9%) 40 0.0079482 1 0.4658 1 0.05138 1 1 1 1 1 0.081517 1 0.60692 1 1 1 NA NA NA NA 1 1 0.86137 1 ZNF608 6 (14%) 38 0.21289 1 0.40837 1 0.15753 1 1 1 1 1 0.31296 1 0.66403 1 1 1 NA NA NA NA 0.10018 1 0.68789 1 NEDD4L 5 (11%) 39 0.61459 1 0.5023 1 0.5299 1 0.057495 1 1 1 0.48809 1 1 1 1 1 NA NA NA NA 0.71641 1 0.64757 1 THBS4 6 (14%) 38 0.70153 1 0.85905 1 0.07793 1 0.45625 1 0.60582 1 1 1 0.18528 1 1 1 NA NA NA NA 0.54705 1 0.33115 1 MMRN1 6 (14%) 38 0.55451 1 0.42377 1 0.94644 1 1 1 1 1 0.7513 1 0.66403 1 1 1 NA NA NA NA 0.54705 1 0.38641 1 GPR25 3 (7%) 41 0.79641 1 0.2721 1 0.95645 1 1 1 1 1 0.65116 1 1 1 1 1 NA NA NA NA 0.37523 1 0.79452 1 SORBS2 5 (11%) 39 0.19868 1 0.26879 1 0.86544 1 1 1 0.57297 1 0.48809 1 1 1 1 1 NA NA NA NA 1 1 0.34025 1 ECSIT 4 (9%) 40 0.00060353 0.617 0.46841 1 0.0054677 1 0.32678 1 0.031602 1 0.4498 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 6.3476e-06 0.00651 ZNF326 4 (9%) 40 0.554 1 0.97836 1 0.91688 1 1 1 0.55919 1 1 1 0.60692 1 1 1 NA NA NA NA 1 1 0.72285 1 C15ORF52 3 (7%) 41 0.24895 1 0.94683 1 0.95645 1 1 1 1 1 0.65116 1 1 1 1 1 NA NA NA NA 1 1 0.40318 1 SLC39A5 3 (7%) 41 0.64815 1 0.35805 1 0.95645 1 1 1 1 1 1 1 0.23256 1 1 1 NA NA NA NA 0.37523 1 0.25135 1 SLC24A1 4 (9%) 40 0.79641 1 0.89511 1 0.42201 1 0.32678 1 1 1 0.4498 1 1 1 1 1 NA NA NA NA 0.30621 1 0.3699 1 PUM2 5 (11%) 39 0.9927 1 0.16747 1 0.10984 1 1 1 0.31675 1 0.48809 1 1 1 1 1 NA NA NA NA 0.17778 1 0.68141 1 SYT2 5 (11%) 39 0.14725 1 0.02552 1 0.86544 1 1 1 0.57297 1 1 1 1 1 1 1 NA NA NA NA 0.17778 1 0.43903 1 SLITRK5 6 (14%) 38 0.9927 1 0.1561 1 0.19528 1 1 1 0.60582 1 0.7513 1 1 1 1 1 NA NA NA NA 0.10018 1 0.48037 1 NAP1L3 3 (7%) 41 NA NA 0.89655 1 0.25562 1 0.254 1 0.54817 1 0.65116 1 1 1 1 1 NA NA NA NA 1 1 0.17656 1 PHF14 3 (7%) 41 0.22181 1 0.16087 1 0.8713 1 1 1 0.54817 1 1 1 1 1 1 1 NA NA NA NA 0.37523 1 0.48783 1 CCDC28B 4 (9%) 40 0.71484 1 0.88749 1 0.0054677 1 0.32678 1 0.031602 1 0.4498 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 0.764 1 PDE12 3 (7%) 41 0.0079482 1 0.89771 1 0.95645 1 1 1 1 1 0.21927 1 1 1 1 1 NA NA NA NA NA NA 0.87193 1 FLAD1 3 (7%) 41 NA NA 0.98213 1 0.25562 1 0.254 1 0.54817 1 0.21927 1 1 1 1 1 NA NA NA NA 0.37523 1 0.37953 1 ENG 3 (7%) 41 NA NA 0.33474 1 0.25562 1 0.254 1 0.54817 1 1 1 1 1 1 1 NA NA NA NA 0.37523 1 0.97552 1 PABPC1 4 (9%) 40 0.15762 1 0.045871 1 0.91688 1 1 1 0.55919 1 1 1 0.60692 1 1 1 NA NA NA NA 1 1 0.49423 1 ATG16L2 3 (7%) 41 0.27801 1 0.83563 1 0.013107 1 1 1 0.54817 1 1 1 1 1 1 1 NA NA NA NA 1 1 0.48783 1 LRCH1 7 (16%) 37 0.59248 1 0.8294 1 0.0034419 1 0.11282 1 0.036671 1 1 1 0.41206 1 1 1 NA NA NA NA 0.065464 1 0.03204 1 PLCZ1 3 (7%) 41 0.98304 1 0.26379 1 0.00085821 0.875 0.254 1 0.12458 1 0.65116 1 1 1 1 1 NA NA NA NA 0.37523 1 0.00022672 0.232 TAOK2 4 (9%) 40 0.84089 1 0.67637 1 0.35394 1 0.32678 1 0.21757 1 1 1 0.60692 1 1 1 NA NA NA NA 1 1 0.48072 1 ZMIZ1 5 (11%) 39 0.77381 1 0.29347 1 0.94882 1 1 1 1 1 1 1 0.34487 1 1 1 NA NA NA NA 0.048204 1 0.014503 1 SYT15 6 (14%) 38 0.31597 1 0.56875 1 0.07793 1 1 1 0.60582 1 0.11542 1 1 1 1 1 NA NA NA NA 0.75186 1 0.33328 1 LRTM1 3 (7%) 41 0.018221 1 0.64613 1 0.8713 1 1 1 0.54817 1 1 1 0.23256 1 1 1 NA NA NA NA 0.37523 1 0.86689 1 TIMM50 3 (7%) 41 0.53053 1 0.25878 1 0.8713 1 1 1 0.54817 1 0.33555 1 1 1 1 1 NA NA NA NA 0.37523 1 0.26099 1 CCNK 4 (9%) 40 0.53053 1 0.23025 1 0.93286 1 1 1 1 1 0.67669 1 0.60692 1 1 1 NA NA NA NA 0.30621 1 0.092598 1 TTK 5 (11%) 39 0.49493 1 0.051688 1 0.94882 1 1 1 1 1 1 1 0.34487 1 1 1 NA NA NA NA 0.71641 1 0.48761 1 TMEM175 4 (9%) 40 0.48437 1 0.97569 1 0.91688 1 1 1 0.55919 1 0.67669 1 1 1 1 1 NA NA NA NA 1 1 0.14545 1 CD93 5 (11%) 39 0.64097 1 0.94882 1 0.029228 1 0.3941 1 0.068795 1 1 1 0.34487 1 1 1 NA NA NA NA 0.048204 1 0.022067 1 C19ORF55 4 (9%) 40 0.15048 1 0.26034 1 0.91688 1 1 1 0.55919 1 0.67669 1 0.60692 1 1 1 NA NA NA NA 0.70021 1 0.34133 1 MRPL48 3 (7%) 41 0.79641 1 0.64589 1 0.95645 1 1 1 1 1 1 1 1 1 1 1 NA NA NA NA 0.37523 1 0.5442 1 PVRL1 5 (11%) 39 0.98519 1 0.83995 1 0.5299 1 0.3941 1 1 1 0.73057 1 1 1 1 1 NA NA NA NA 0.17778 1 0.96481 1 ACIN1 3 (7%) 41 0.57493 1 0.65398 1 0.95645 1 1 1 1 1 0.65116 1 1 1 1 1 NA NA NA NA 1 1 0.27986 1 MAML3 6 (14%) 38 0.22937 1 0.49692 1 0.15753 1 1 1 1 1 0.31296 1 0.66403 1 1 1 NA NA NA NA 0.75186 1 0.53518 1 EDC4 4 (9%) 40 0.40154 1 0.91401 1 0.91688 1 1 1 0.55919 1 0.67669 1 1 1 1 1 NA NA NA NA 1 1 0.41254 1