Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.112 0.187 0.336 21.0 -9999.0 0.0 21.0 KIRREL -0.02 0.105 -9999.0 0.0 -0.525 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.112 0.187 -9999.0 0.0 -0.336 21.0 21.0 PLCG1 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.075 0.171 -9999.0 0.0 -0.377 8.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.054 0.123 -9999.0 0.0 -0.334 7.0 7.0 FYN -0.085 0.146 0.266 1.0 -0.353 8.0 9.0 mol:Ca2+ -0.068 0.165 -9999.0 0.0 -0.388 7.0 7.0 mol:DAG -0.068 0.167 -9999.0 0.0 -0.39 7.0 7.0 NPHS2 -0.037 0.117 -9999.0 0.0 -0.435 4.0 4.0 mol:IP3 -0.068 0.167 -9999.0 0.0 -0.39 7.0 7.0 regulation of endocytosis -0.063 0.146 -9999.0 0.0 -0.345 7.0 7.0 Nephrin/NEPH1/podocin/Cholesterol -0.083 0.163 -9999.0 0.0 -0.284 17.0 17.0 establishment of cell polarity -0.112 0.187 -9999.0 0.0 -0.336 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 -0.057 0.162 -9999.0 0.0 -0.435 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.063 0.148 -9999.0 0.0 -0.349 7.0 7.0 NPHS1 -0.156 0.233 -9999.0 0.0 -0.448 21.0 21.0 Nephrin/NEPH1/podocin -0.074 0.153 -9999.0 0.0 -0.355 8.0 8.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.067 0.168 -9999.0 0.0 -0.392 7.0 7.0 CD2AP 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.073 0.166 -9999.0 0.0 -0.388 7.0 7.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.085 0.137 -9999.0 0.0 -0.359 7.0 7.0 cytoskeleton organization -0.078 0.149 -9999.0 0.0 -0.418 7.0 7.0 Nephrin/NEPH1 -0.074 0.134 -9999.0 0.0 -0.233 21.0 21.0 Nephrin/NEPH1/ZO-1 -0.076 0.158 -9999.0 0.0 -0.343 8.0 8.0