Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.012 0.212 -9999.0 0.0 -0.66 4.0 4.0 MAP3K8 0.017 0.073 -9999.0 0.0 -0.52 1.0 1.0 FOS -0.022 0.208 -9999.0 0.0 -0.69 4.0 4.0 PRKCA 0.024 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.006 0.103 -9999.0 0.0 -0.52 2.0 2.0 HRAS 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.032 0.165 -9999.0 0.0 -0.5 6.0 6.0 NRAS 0.028 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.045 0.021 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.012 0.18 -9999.0 0.0 -0.876 2.0 2.0 MAP2K1 -0.029 0.19 -9999.0 0.0 -0.603 5.0 5.0 ELK1 0.026 0.013 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.037 0.185 -9999.0 0.0 -0.606 5.0 5.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 3.0 3.0 MAPK1 -0.024 0.216 -9999.0 0.0 -0.731 4.0 4.0 RAF1 -0.026 0.147 -9999.0 0.0 -0.476 5.0 5.0 KRAS 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0