Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 7 (3%) 271 0.035054 1 0.092087 1 0.041065 1 0.49508 1 0.59507 1 0.13959 1 0.75391 1 1 1 0.79723 1 0.89045 1 1q gain 11 (4%) 267 0.01284 1 0.025545 1 0.022254 1 0.22387 1 0.2499 1 0.062767 1 0.72009 1 0.92201 1 1 1 0.85276 1 2p gain 4 (1%) 274 0.49836 1 0.10491 1 NA NA NA NA 0.23258 1 0.17646 1 0.26455 1 0.69612 1 0.11151 1 0.69053 1 2q gain 3 (1%) 275 0.15438 1 0.28938 1 NA NA NA NA 0.55946 1 0.34613 1 0.083613 1 0.10344 1 0.02647 1 0.19814 1 3p gain 19 (7%) 259 0.001312 0.778 0.069206 1 0.056137 1 0.45971 1 0.6542 1 0.059058 1 0.3932 1 1 1 0.73182 1 0.38883 1 3q gain 25 (9%) 253 7.2471e-06 0.00449 0.10623 1 0.039638 1 0.24753 1 0.25112 1 0.016274 1 0.58716 1 0.80394 1 0.77441 1 0.43278 1 4p gain 4 (1%) 274 0.49836 1 0.39143 1 NA NA NA NA 0.84276 1 0.75114 1 0.62761 1 0.484 1 0.5543 1 0.38998 1 4q gain 3 (1%) 275 0.74948 1 0.50931 1 NA NA NA NA 1 1 1 1 0.63213 1 0.46125 1 0.64402 1 0.77882 1 5p gain 6 (2%) 272 0.001389 0.822 0.16394 1 0.29809 1 0.38677 1 0.63713 1 0.80261 1 0.29506 1 0.076134 1 0.16494 1 0.12865 1 5q gain 3 (1%) 275 0.059833 1 0.11275 1 NA NA NA NA 0.49439 1 0.77635 1 NA NA NA NA NA NA NA NA 7p gain 46 (17%) 232 5.5322e-07 0.000348 1.0491e-06 0.000657 0.4133 1 0.56093 1 6.6096e-05 0.0405 0.021888 1 0.41817 1 0.96163 1 0.72994 1 0.90172 1 7q gain 43 (15%) 235 4.3593e-06 0.0027 1.7308e-06 0.00108 0.58591 1 0.55136 1 8.814e-05 0.0537 0.057204 1 0.41532 1 0.82945 1 0.72751 1 0.87023 1 8p gain 34 (12%) 244 8.9482e-14 5.69e-11 2.406e-07 0.000152 0.0051135 1 0.019326 1 0.0086806 1 0.00065681 0.393 0.31647 1 0.37935 1 0.33054 1 0.69029 1 8q gain 59 (21%) 219 1.9147e-15 1.22e-12 2.0523e-05 0.0127 0.0012962 0.77 0.0049163 1 0.010103 1 2.3759e-05 0.0146 0.022464 1 0.025809 1 0.099762 1 0.2441 1 9p gain 10 (4%) 268 0.00048099 0.289 0.66186 1 0.48418 1 0.19994 1 0.97025 1 0.65587 1 0.77425 1 0.2444 1 0.56235 1 0.17316 1 9q gain 20 (7%) 258 9.2249e-07 0.000579 0.37808 1 0.028107 1 0.011234 1 0.86924 1 0.15793 1 0.38743 1 0.071156 1 0.38664 1 0.48168 1 10p gain 7 (3%) 271 0.0030529 1 0.30176 1 0.78437 1 0.63505 1 1 1 0.094508 1 0.033888 1 0.034278 1 0.052636 1 0.080365 1 10q gain 8 (3%) 270 0.00099421 0.593 0.31905 1 0.040303 1 0.037622 1 0.96284 1 0.073332 1 0.27288 1 0.26619 1 0.12468 1 0.63879 1 11p gain 9 (3%) 269 0.0017022 1 0.29497 1 0.76789 1 0.58549 1 0.23625 1 0.26708 1 0.94284 1 1 1 1 1 0.81932 1 11q gain 9 (3%) 269 0.0017022 1 0.29497 1 0.76789 1 0.58549 1 0.23625 1 0.26708 1 0.94284 1 1 1 1 1 0.81932 1 12q gain 5 (2%) 273 0.25236 1 0.10321 1 0.84816 1 0.86319 1 0.4434 1 0.17763 1 0.90894 1 0.17658 1 1 1 0.27893 1 14q gain 5 (2%) 273 0.017849 1 0.036396 1 0.78437 1 0.63505 1 0.069991 1 0.056218 1 0.032925 1 0.22607 1 0.025306 1 0.10031 1 15q gain 3 (1%) 275 0.58247 1 1 1 NA NA NA NA 0.79005 1 1 1 0.13599 1 0.25607 1 0.77715 1 0.77882 1 16p gain 14 (5%) 264 0.00046405 0.279 0.2541 1 0.52084 1 0.3895 1 0.69419 1 0.14791 1 0.24722 1 0.60641 1 0.2777 1 0.34322 1 16q gain 5 (2%) 273 0.0777 1 0.85998 1 0.67723 1 0.46645 1 0.47008 1 0.57325 1 0.82987 1 0.86251 1 1 1 1 1 17q gain 4 (1%) 274 0.01515 1 0.83319 1 0.47143 1 0.63505 1 0.67179 1 0.75114 1 0.89432 1 0.81439 1 0.83793 1 0.8304 1 18p gain 9 (3%) 269 0.00024861 0.15 0.6927 1 1 1 0.56384 1 0.38897 1 0.4031 1 0.6171 1 0.62695 1 1 1 1 1 18q gain 4 (1%) 274 0.01515 1 0.83319 1 1 1 0.38478 1 0.84276 1 0.34959 1 0.57024 1 0.69612 1 0.68819 1 0.69053 1 19p gain 3 (1%) 275 0.059833 1 0.50931 1 NA NA NA NA 0.628 1 0.15232 1 NA NA NA NA NA NA NA NA 19q gain 4 (1%) 274 0.01515 1 0.39143 1 0.78437 1 0.63505 1 0.45013 1 0.037583 1 NA NA NA NA NA NA NA NA 20p gain 6 (2%) 272 0.098099 1 0.066159 1 0.37099 1 0.1451 1 0.097884 1 0.079802 1 0.36409 1 0.13111 1 0.23446 1 0.2329 1 20q gain 8 (3%) 270 0.015081 1 0.14296 1 0.62114 1 0.79785 1 0.38004 1 0.40895 1 0.82696 1 0.59822 1 0.90515 1 0.90731 1 21q gain 6 (2%) 272 0.001389 0.822 0.16394 1 0.44456 1 0.32596 1 0.20037 1 0.35566 1 0.43341 1 0.4532 1 0.27756 1 0.32945 1 1p loss 8 (3%) 270 0.015081 1 0.087005 1 0.25549 1 0.15469 1 0.056391 1 0.028728 1 0.27452 1 0.29382 1 0.14212 1 0.16489 1 2p loss 3 (1%) 275 0.059833 1 0.11275 1 NA NA NA NA 0.49439 1 0.15232 1 0.63872 1 0.62207 1 0.52102 1 0.63951 1 2q loss 4 (1%) 274 0.01515 1 0.46301 1 NA NA NA NA 0.61911 1 0.38413 1 0.63792 1 0.38716 1 0.2682 1 0.3195 1 3p loss 4 (1%) 274 0.2257 1 0.32058 1 NA NA NA NA 0.28329 1 0.25382 1 0.25783 1 1 1 1 1 1 1 4p loss 9 (3%) 269 0.018893 1 0.32574 1 0.29809 1 1 1 0.039308 1 0.13312 1 0.038208 1 0.0028101 1 0.075603 1 0.049289 1 4q loss 6 (2%) 272 0.098099 1 0.51781 1 0.78437 1 0.38478 1 0.097884 1 0.2949 1 0.26686 1 0.096775 1 0.081766 1 0.11475 1 5p loss 4 (1%) 274 0.01515 1 0.39143 1 0.78437 1 1 1 0.45013 1 0.037583 1 0.96042 1 1 1 1 1 1 1 5q loss 8 (3%) 270 0.00013668 0.083 0.31905 1 0.25549 1 0.15469 1 0.29947 1 0.10335 1 0.72628 1 0.36535 1 1 1 0.71471 1 6p loss 9 (3%) 269 3.1823e-05 0.0195 0.0034206 1 0.25549 1 0.15469 1 0.0045495 1 0.0020567 1 0.56546 1 0.83236 1 0.91394 1 0.91591 1 6q loss 16 (6%) 262 2.0139e-06 0.00125 0.0018961 1 0.076129 1 0.50153 1 0.0090286 1 0.0043453 1 0.49932 1 0.68748 1 0.72891 1 0.87546 1 8p loss 85 (31%) 193 2.9108e-06 0.00181 1.1933e-08 7.55e-06 0.54279 1 0.90364 1 9.3381e-07 0.000585 6.9264e-05 0.0423 0.00055427 0.333 0.77601 1 0.42828 1 0.57194 1 8q loss 11 (4%) 267 4.2653e-06 0.00265 0.24546 1 0.72964 1 1 1 0.05154 1 0.0026188 1 0.20192 1 0.25356 1 0.22758 1 0.086536 1 9p loss 12 (4%) 266 0.00037262 0.225 0.81225 1 0.085491 1 0.34847 1 0.16295 1 0.29574 1 0.24633 1 0.12471 1 0.24561 1 0.25066 1 9q loss 5 (2%) 273 0.017849 1 0.4472 1 0.44456 1 0.86319 1 0.64823 1 0.75941 1 0.40331 1 0.4532 1 0.86333 1 0.8654 1 10p loss 18 (6%) 260 8.669e-06 0.00536 0.00096593 0.577 0.0068249 1 0.03105 1 0.0067729 1 0.015626 1 0.34164 1 0.55426 1 0.1797 1 0.4704 1 10q loss 22 (8%) 256 3.9804e-07 0.000251 0.025454 1 0.039237 1 0.049752 1 0.13706 1 0.065739 1 0.44464 1 0.5171 1 0.15922 1 0.20478 1 12p loss 26 (9%) 252 0.00045305 0.273 0.090147 1 0.1857 1 0.64669 1 0.095442 1 0.10178 1 0.86447 1 0.18911 1 0.31663 1 0.78444 1 12q loss 11 (4%) 267 0.00012586 0.0765 0.46564 1 0.29692 1 0.49508 1 0.29174 1 0.31248 1 0.51789 1 0.34673 1 0.63704 1 0.69459 1 13q loss 39 (14%) 239 1.1348e-07 7.17e-05 0.31758 1 0.54251 1 0.5449 1 0.91557 1 0.37 1 0.81476 1 0.91146 1 0.77599 1 0.79144 1 14q loss 10 (4%) 268 0.095797 1 0.21202 1 0.46398 1 0.34847 1 0.47405 1 0.45716 1 0.0012285 0.731 0.010483 1 0.00069517 0.416 0.0017035 1 15q loss 16 (6%) 262 7.1573e-05 0.0437 0.035177 1 0.041296 1 0.087854 1 0.22109 1 0.061362 1 0.18099 1 0.74633 1 0.1923 1 0.4704 1 16p loss 16 (6%) 262 0.0088661 1 0.18752 1 0.59861 1 0.59943 1 0.34404 1 0.36473 1 0.38752 1 0.62918 1 0.36443 1 0.56099 1 16q loss 53 (19%) 225 1.2742e-10 8.09e-08 0.0044948 1 0.49169 1 0.2994 1 0.054586 1 0.015726 1 0.61455 1 1 1 0.17239 1 0.3972 1 17p loss 38 (14%) 240 7.3949e-14 4.71e-11 0.0020805 1 0.0034438 1 0.014101 1 0.0019493 1 2.9995e-05 0.0184 0.69058 1 0.83163 1 0.68913 1 0.6156 1 17q loss 7 (3%) 271 0.0030529 1 0.019814 1 0.4517 1 0.31352 1 0.010925 1 0.098747 1 0.74014 1 0.88168 1 0.14212 1 0.16489 1 18p loss 34 (12%) 244 1.5787e-06 0.000987 0.028576 1 0.063325 1 0.079442 1 0.055444 1 0.021547 1 0.36461 1 0.49137 1 0.19894 1 0.26506 1 18q loss 50 (18%) 228 6.0253e-09 3.82e-06 0.031005 1 0.015976 1 0.018818 1 0.012186 1 0.014037 1 0.64612 1 0.74158 1 0.6801 1 0.76931 1 19p loss 9 (3%) 269 0.018893 1 0.76277 1 0.67723 1 1 1 0.67029 1 0.96365 1 0.45899 1 0.33909 1 0.39673 1 0.35687 1 19q loss 9 (3%) 269 0.018893 1 0.76277 1 0.67723 1 1 1 0.67029 1 0.96365 1 0.45899 1 0.33909 1 0.39673 1 0.35687 1 20p loss 10 (4%) 268 0.46251 1 0.035335 1 0.89585 1 1 1 0.83235 1 0.47745 1 0.7253 1 0.20403 1 0.91394 1 0.47863 1 20q loss 6 (2%) 272 0.098099 1 0.066159 1 1 1 0.86319 1 0.66866 1 0.16333 1 0.63815 1 0.66219 1 0.59668 1 0.29005 1 21q loss 9 (3%) 269 0.072327 1 0.29497 1 0.50529 1 0.44539 1 0.52778 1 0.18493 1 0.58097 1 0.42332 1 0.54501 1 0.81932 1 22q loss 19 (7%) 259 0.00019332 0.117 0.20325 1 0.44243 1 0.80454 1 0.29276 1 0.095853 1 0.788 1 0.63879 1 0.53398 1 0.6428 1 xq loss 18 (6%) 260 6.2886e-05 0.0385 0.0014273 0.842 0.19256 1 0.2354 1 0.0039961 1 0.026328 1 0.27757 1 0.28145 1 0.13952 1 0.18076 1