Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.025 0.142 0.533 11.0 -9999.0 0.0 11.0 KIRREL 0.007 0.017 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.025 0.142 -9999.0 0.0 -0.534 11.0 11.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.016 0.118 -9999.0 0.0 -0.407 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.004 0.068 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.014 0.099 -9999.0 0.0 -0.351 12.0 12.0 mol:Ca2+ -0.01 0.112 -9999.0 0.0 -0.392 12.0 12.0 mol:DAG -0.01 0.112 -9999.0 0.0 -0.394 12.0 12.0 NPHS2 -0.004 0.059 -9999.0 0.0 -0.71 1.0 1.0 mol:IP3 -0.01 0.112 -9999.0 0.0 -0.394 12.0 12.0 regulation of endocytosis -0.003 0.095 -9999.0 0.0 -0.327 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.017 0.112 -9999.0 0.0 -0.401 12.0 12.0 establishment of cell polarity -0.025 0.142 -9999.0 0.0 -0.533 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 -0.001 0.105 -9999.0 0.0 -0.359 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.003 0.096 -9999.0 0.0 -0.331 12.0 12.0 NPHS1 -0.04 0.185 -9999.0 0.0 -0.711 11.0 11.0 Nephrin/NEPH1/podocin -0.011 0.1 -9999.0 0.0 -0.353 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.01 0.113 -9999.0 0.0 -0.396 12.0 12.0 CD2AP 0.001 0.057 -9999.0 0.0 -0.282 6.0 6.0 Nephrin/NEPH1/podocin/GRB2 -0.01 0.113 -9999.0 0.0 -0.396 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.104 -9999.0 0.0 -0.362 12.0 12.0 cytoskeleton organization 0.002 0.086 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.017 0.104 -9999.0 0.0 -0.391 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.011 0.117 -9999.0 0.0 -0.432 11.0 11.0