Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.023 0.066 0.202 11.0 -0.214 1.0 12.0 KIRREL 0.024 0.017 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.023 0.066 0.214 1.0 -0.202 11.0 12.0 PLCG1 0.015 0.013 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.042 0.073 0.211 1.0 -0.16 16.0 17.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.016 0.025 -9999.0 0.0 -0.168 1.0 1.0 FYN -0.015 0.055 0.218 5.0 -9999.0 0.0 5.0 mol:Ca2+ 0.03 0.051 0.203 1.0 -0.151 6.0 7.0 mol:DAG 0.031 0.052 0.207 1.0 -0.152 6.0 7.0 NPHS2 -0.006 0.036 -9999.0 0.0 -0.307 1.0 1.0 mol:IP3 0.031 0.052 0.207 1.0 -0.152 6.0 7.0 regulation of endocytosis 0.033 0.049 0.192 1.0 -9999.0 0.0 1.0 Nephrin/NEPH1/podocin/Cholesterol 0.034 0.055 0.193 1.0 -0.149 11.0 12.0 establishment of cell polarity 0.023 0.066 0.214 1.0 -0.202 11.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 0.061 0.06 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 0.035 0.05 0.199 1.0 -9999.0 0.0 1.0 NPHS1 0.009 0.086 0.293 2.0 -0.307 9.0 11.0 Nephrin/NEPH1/podocin 0.035 0.048 0.195 1.0 -0.128 11.0 12.0 TJP1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.032 0.053 0.211 1.0 -0.152 6.0 7.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.048 0.061 0.211 1.0 -0.154 11.0 12.0 GRB2 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.016 0.057 0.223 5.0 -9999.0 0.0 5.0 cytoskeleton organization -0.006 0.032 0.197 1.0 -0.171 1.0 2.0 Nephrin/NEPH1 0.022 0.046 0.176 1.0 -0.133 11.0 12.0 Nephrin/NEPH1/ZO-1 0.036 0.059 0.205 1.0 -0.166 10.0 11.0