Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.022	0.177	0.265	2.0	-0.46	13.0	15.0
IHH	0.015	0.059	0.12	4.0	-0.127	13.0	17.0
SHH Np/Cholesterol/GAS1	0.009	0.043	-9999.0	0.0	-0.132	8.0	8.0
LRPAP1	0.027	0.007	-9999.0	0.0	0.0	7.0	7.0
dorsoventral neural tube patterning	-0.009	0.042	0.132	8.0	-9999.0	0.0	8.0
SMO/beta Arrestin2	-0.019	0.144	-9999.0	0.0	-0.313	13.0	13.0
SMO	-0.03	0.14	0.206	2.0	-0.329	12.0	14.0
AKT1	-0.001	0.109	-9999.0	0.0	-0.494	3.0	3.0
ARRB2	0.025	0.01	-9999.0	0.0	0.0	13.0	13.0
BOC	0.026	0.009	-9999.0	0.0	0.0	11.0	11.0
ADRBK1	0.028	0.004	-9999.0	0.0	0.0	2.0	2.0
heart looping	-0.029	0.138	0.206	2.0	-0.325	12.0	14.0
STIL	-0.019	0.104	0.168	8.0	-0.245	12.0	20.0
DHH N/PTCH2	0.02	0.062	-9999.0	0.0	-0.173	9.0	9.0
DHH N/PTCH1	0.001	0.114	0.202	1.0	-0.271	13.0	14.0
PIK3CA	0.028	0.005	-9999.0	0.0	0.0	3.0	3.0
DHH	0.025	0.009	-9999.0	0.0	0.0	11.0	11.0
PTHLH	-0.055	0.259	0.295	2.0	-0.703	13.0	15.0
determination of left/right symmetry	-0.029	0.138	0.206	2.0	-0.325	12.0	14.0
PIK3R1	0.028	0.004	-9999.0	0.0	0.0	2.0	2.0
skeletal system development	-0.054	0.256	0.294	2.0	-0.696	13.0	15.0
IHH N/Hhip	0.014	0.067	-9999.0	0.0	-0.22	5.0	5.0
DHH N/Hhip	0.011	0.067	-9999.0	0.0	-0.175	11.0	11.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.029	0.138	0.206	2.0	-0.325	12.0	14.0
pancreas development	0.021	0.011	-9999.0	0.0	0.0	18.0	18.0
HHAT	0.027	0.008	-9999.0	0.0	0.0	8.0	8.0
PI3K	0.041	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.027	0.007	-9999.0	0.0	0.0	7.0	7.0
somite specification	-0.029	0.138	0.206	2.0	-0.325	12.0	14.0
SHH Np/Cholesterol/PTCH1	-0.008	0.1	0.161	3.0	-0.252	12.0	15.0
SHH Np/Cholesterol/PTCH2	0.009	0.042	-9999.0	0.0	-0.141	7.0	7.0
SHH Np/Cholesterol/Megalin	0.001	0.035	-9999.0	0.0	-0.136	4.0	4.0
SHH	-0.021	0.037	0.079	3.0	-0.184	4.0	7.0
catabolic process	-0.008	0.12	0.21	3.0	-0.302	13.0	16.0
SMO/Vitamin D3	-0.019	0.119	0.181	3.0	-0.289	13.0	16.0
SHH Np/Cholesterol/Hhip	-0.004	0.046	-9999.0	0.0	-0.141	9.0	9.0
LRP2	0.023	0.008	-9999.0	0.0	0.0	7.0	7.0
receptor-mediated endocytosis	-0.018	0.118	0.175	2.0	-0.285	13.0	15.0
SHH Np/Cholesterol/BOC	0.004	0.058	-9999.0	0.0	-0.162	10.0	10.0
SHH Np/Cholesterol/CDO	0.013	0.037	-9999.0	0.0	-0.141	5.0	5.0
mesenchymal cell differentiation	0.004	0.046	0.14	9.0	-9999.0	0.0	9.0
mol:Vitamin D3	-0.001	0.107	0.187	7.0	-0.252	12.0	19.0
IHH N/PTCH2	0.023	0.055	-9999.0	0.0	-0.123	7.0	7.0
CDON	0.026	0.008	-9999.0	0.0	0.0	9.0	9.0
IHH N/PTCH1	0.0	0.122	0.234	2.0	-0.304	13.0	15.0
Megalin/LRPAP1	0.034	0.014	-9999.0	0.0	-9999.0	0.0	0.0
PTCH2	0.026	0.009	-9999.0	0.0	0.0	10.0	10.0
SHH Np/Cholesterol	-0.009	0.031	0.072	3.0	-0.135	4.0	7.0
PTCH1	-0.008	0.12	0.21	3.0	-0.303	13.0	16.0
HHIP	0.021	0.011	-9999.0	0.0	0.0	18.0	18.0