Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 65 (22%) 227 0.32007 1 1 1 0.82748 1 0.3475 1 0.15676 1 0.21344 1 0.87887 1 0.86669 1 0.79634 1 0.71602 1 1q gain 130 (45%) 162 5.6161e-07 0.00044 0.17226 1 0.22551 1 0.94976 1 0.021499 1 0.092727 1 0.12022 1 0.16676 1 0.025087 1 0.039388 1 2p gain 57 (20%) 235 0.020554 1 0.64697 1 0.46061 1 0.50273 1 0.033098 1 0.0030467 1 0.01737 1 0.0032854 1 0.012258 1 0.0007274 0.551 2q gain 55 (19%) 237 0.0061976 1 0.93093 1 0.80856 1 0.18484 1 0.0025574 1 0.0014848 1 0.0016274 1 0.0003835 0.292 0.0028903 1 5.1683e-05 0.0398 3p gain 47 (16%) 245 0.85966 1 0.27011 1 0.036953 1 0.0058795 1 0.36258 1 0.54153 1 0.87964 1 0.030961 1 0.4441 1 0.23745 1 3q gain 57 (20%) 235 0.32739 1 0.63933 1 0.02448 1 0.012154 1 0.034289 1 0.16465 1 0.70465 1 0.025478 1 0.40028 1 0.67589 1 4p gain 44 (15%) 248 0.0017894 1 0.11328 1 0.20508 1 0.41341 1 0.71782 1 0.15915 1 0.22639 1 0.029272 1 0.15681 1 0.18798 1 4q gain 37 (13%) 255 0.00062888 0.477 0.039721 1 0.24211 1 0.8103 1 0.63888 1 0.10909 1 0.29892 1 0.11759 1 0.36283 1 0.3581 1 5p gain 57 (20%) 235 2.1586e-05 0.0167 0.29734 1 0.9195 1 0.54975 1 0.37855 1 0.78123 1 0.031219 1 0.27682 1 0.055171 1 0.24396 1 5q gain 35 (12%) 257 0.0090801 1 0.28209 1 0.47277 1 0.14668 1 0.94126 1 0.50358 1 0.013855 1 0.29866 1 0.028652 1 0.038086 1 6p gain 117 (40%) 175 2.6298e-09 2.07e-06 0.00104 0.781 0.86631 1 0.055733 1 0.31634 1 0.018215 1 0.017829 1 0.00036742 0.28 0.031303 1 0.00012622 0.0969 6q gain 38 (13%) 254 0.051753 1 0.22861 1 0.75098 1 0.31205 1 0.59203 1 0.77051 1 0.24164 1 0.19278 1 0.36617 1 0.074412 1 7p gain 157 (54%) 135 4.7321e-06 0.00368 0.69404 1 0.48179 1 0.97507 1 0.027226 1 0.33276 1 0.7114 1 0.1748 1 0.85394 1 0.5601 1 7q gain 155 (53%) 137 3.2239e-07 0.000253 0.51004 1 0.73464 1 0.97297 1 0.0059072 1 0.10023 1 0.52655 1 0.044785 1 0.43096 1 0.35125 1 8p gain 93 (32%) 199 0.00019386 0.148 0.21325 1 0.796 1 0.69481 1 0.025874 1 0.099168 1 0.15511 1 0.64277 1 0.046985 1 0.45854 1 8q gain 134 (46%) 158 1.3452e-06 0.00105 0.003844 1 0.47801 1 0.62438 1 0.0031773 1 0.089245 1 0.11666 1 0.17667 1 0.06503 1 0.14782 1 9p gain 15 (5%) 277 0.34329 1 0.21839 1 0.34702 1 0.5514 1 0.44988 1 0.83932 1 1 1 0.72103 1 0.80063 1 0.47844 1 9q gain 20 (7%) 272 0.50553 1 0.83191 1 0.11298 1 0.35763 1 0.51665 1 0.59191 1 0.8704 1 0.7659 1 0.84584 1 0.7005 1 10p gain 9 (3%) 283 0.63751 1 0.69282 1 0.58453 1 0.30592 1 1 1 0.68927 1 0.43499 1 0.061792 1 0.60444 1 0.38337 1 11p gain 29 (10%) 263 0.032811 1 0.48516 1 0.082168 1 0.032781 1 0.011349 1 0.10029 1 0.15267 1 0.043475 1 0.11062 1 0.18102 1 11q gain 25 (9%) 267 0.0063061 1 0.33623 1 0.075994 1 0.023795 1 0.015115 1 0.28876 1 0.12688 1 0.010496 1 0.10709 1 0.07565 1 12p gain 48 (16%) 244 0.0030107 1 0.40829 1 0.58798 1 0.1272 1 0.020061 1 0.03104 1 0.83864 1 0.67896 1 0.81323 1 0.9744 1 12q gain 30 (10%) 262 0.16224 1 0.88684 1 0.59615 1 0.075755 1 0.34073 1 0.32836 1 0.7916 1 0.8156 1 0.484 1 0.78881 1 13q gain 73 (25%) 219 0.00030427 0.232 1.1194e-06 0.000875 0.41838 1 0.70071 1 0.026572 1 0.024838 1 0.73019 1 0.33294 1 0.82014 1 0.4889 1 14q gain 31 (11%) 261 0.7748 1 0.32261 1 0.34529 1 0.018125 1 0.96126 1 0.94199 1 0.19983 1 0.16102 1 0.67599 1 0.94658 1 15q gain 65 (22%) 227 3.0329e-06 0.00237 0.74446 1 0.79092 1 0.60336 1 0.088461 1 0.22936 1 0.27316 1 0.044797 1 0.46326 1 0.32068 1 16p gain 40 (14%) 252 0.010789 1 0.0080184 1 1 1 0.86077 1 0.00045451 0.345 0.017942 1 0.033372 1 0.0018234 1 0.047373 1 0.075526 1 16q gain 34 (12%) 258 0.0037554 1 0.027045 1 0.28237 1 0.65115 1 5.4208e-05 0.0417 0.0053616 1 0.053858 1 0.00066845 0.507 0.10411 1 0.065724 1 17p gain 33 (11%) 259 0.0024715 1 0.011361 1 0.60044 1 0.23694 1 0.23558 1 0.31808 1 0.41482 1 0.2831 1 0.41107 1 0.17697 1 17q gain 58 (20%) 234 0.15263 1 0.11423 1 0.049718 1 0.016008 1 0.58577 1 0.21321 1 0.37483 1 0.68734 1 0.065312 1 0.0040112 1 18p gain 47 (16%) 245 0.028637 1 0.63083 1 0.48165 1 0.33668 1 0.14169 1 0.61462 1 0.76311 1 0.66659 1 0.32201 1 0.62146 1 18q gain 38 (13%) 254 0.020937 1 0.74365 1 0.3513 1 0.84124 1 0.56313 1 0.83928 1 0.93171 1 0.85513 1 0.29819 1 0.89443 1 19p gain 42 (14%) 250 0.044518 1 0.11329 1 0.23307 1 0.5926 1 0.0061536 1 0.0044964 1 0.95904 1 0.50056 1 0.91343 1 0.72163 1 19q gain 44 (15%) 248 0.026382 1 0.026222 1 0.282 1 1 1 0.00084051 0.635 0.00091671 0.69 0.48573 1 0.39382 1 0.52608 1 0.75515 1 20p gain 122 (42%) 170 0.00014994 0.115 0.022714 1 0.74227 1 0.92387 1 0.00090858 0.685 0.010613 1 0.09033 1 0.0014773 1 0.055806 1 0.3367 1 20q gain 145 (50%) 147 6.6573e-05 0.0512 0.04153 1 0.81916 1 0.85808 1 0.0083911 1 0.16988 1 0.59092 1 0.010507 1 0.10841 1 0.4528 1 21q gain 50 (17%) 242 0.48995 1 0.15374 1 0.86907 1 0.74657 1 0.44708 1 0.73644 1 0.31886 1 0.31218 1 0.4822 1 0.86093 1 22q gain 105 (36%) 187 0.010222 1 0.33488 1 0.946 1 0.94368 1 0.12835 1 0.21391 1 0.29246 1 0.41147 1 0.5101 1 0.95528 1 xq gain 30 (10%) 262 0.035787 1 0.023895 1 0.46838 1 0.9083 1 0.052414 1 0.13128 1 0.49942 1 0.37513 1 0.81593 1 0.6029 1 1p loss 37 (13%) 255 0.091637 1 0.026676 1 0.56221 1 0.0317 1 0.051742 1 0.23804 1 0.14205 1 0.074949 1 0.13846 1 0.52548 1 1q loss 20 (7%) 272 0.0064437 1 0.17978 1 0.96943 1 0.3514 1 0.11125 1 0.46656 1 0.11411 1 0.26158 1 0.24453 1 0.38986 1 2p loss 37 (13%) 255 0.047388 1 0.28465 1 0.039117 1 0.0020095 1 0.45035 1 0.1263 1 0.0032433 1 0.0051941 1 0.0079919 1 0.041473 1 2q loss 37 (13%) 255 0.10166 1 0.065693 1 0.010333 1 0.0011024 0.827 0.17838 1 0.087951 1 0.00099529 0.748 0.0044487 1 0.009834 1 0.030181 1 3p loss 46 (16%) 246 0.8889 1 0.5719 1 0.43614 1 0.65849 1 0.11934 1 0.10617 1 0.25864 1 0.32959 1 0.077436 1 0.028042 1 3q loss 35 (12%) 257 0.68059 1 0.21012 1 0.33453 1 0.65287 1 0.47698 1 0.54435 1 0.60137 1 0.42103 1 0.34614 1 0.1875 1 4p loss 62 (21%) 230 0.72064 1 0.37168 1 0.37754 1 0.69182 1 0.47001 1 0.11869 1 0.17464 1 0.034612 1 0.092818 1 0.15261 1 4q loss 64 (22%) 228 0.45629 1 0.137 1 0.48899 1 0.44656 1 0.09459 1 0.0076084 1 0.017503 1 0.0047485 1 0.019282 1 0.018136 1 5p loss 66 (23%) 226 0.63093 1 0.36956 1 0.84717 1 0.91326 1 0.78267 1 0.97785 1 0.63586 1 0.61192 1 0.76939 1 0.88137 1 5q loss 83 (28%) 209 0.93396 1 0.069959 1 0.48259 1 0.65495 1 0.87088 1 0.54091 1 0.87327 1 0.5034 1 0.73411 1 0.50514 1 6p loss 56 (19%) 236 0.0075884 1 0.55862 1 0.91341 1 0.53103 1 0.011523 1 0.0035535 1 0.121 1 0.18774 1 0.039331 1 0.032251 1 6q loss 145 (50%) 147 0.00022758 0.174 0.095423 1 0.92745 1 0.45034 1 0.0053516 1 0.039138 1 0.39803 1 0.67847 1 0.70894 1 0.31935 1 7p loss 14 (5%) 278 1 1 0.060719 1 0.090702 1 0.10435 1 0.52653 1 0.69052 1 0.36898 1 0.382 1 0.46146 1 0.66493 1 7q loss 14 (5%) 278 0.3024 1 0.0047058 1 0.28405 1 0.89207 1 0.16951 1 0.28267 1 0.32143 1 0.56401 1 0.33794 1 0.73756 1 8p loss 53 (18%) 239 0.20123 1 0.69741 1 0.079967 1 0.20884 1 0.32226 1 0.96795 1 0.41088 1 0.22227 1 0.23482 1 0.69639 1 8q loss 21 (7%) 271 0.88006 1 0.095277 1 0.29672 1 0.13049 1 0.5304 1 0.73194 1 0.4555 1 0.70484 1 0.25952 1 0.059115 1 9p loss 193 (66%) 99 5.0074e-07 0.000393 0.041798 1 0.46311 1 0.74829 1 0.019989 1 0.04829 1 0.5768 1 0.078197 1 0.79543 1 0.56666 1 9q loss 150 (51%) 142 0.16309 1 0.067195 1 0.90524 1 0.094152 1 0.089366 1 0.57532 1 0.50428 1 0.57131 1 0.65218 1 0.49447 1 10p loss 164 (56%) 128 3.1538e-08 2.48e-05 0.041773 1 0.84051 1 0.3672 1 4.4295e-05 0.0342 0.00075209 0.569 0.47437 1 0.028624 1 0.47488 1 0.3158 1 10q loss 181 (62%) 111 1.7646e-09 1.39e-06 0.068253 1 0.89528 1 0.1278 1 3.0396e-06 0.00237 1.6227e-05 0.0126 0.82678 1 0.1297 1 0.67005 1 0.59366 1 11p loss 102 (35%) 190 0.029141 1 0.066295 1 0.48455 1 0.2166 1 0.14903 1 0.34274 1 0.71854 1 0.14906 1 0.36205 1 0.41371 1 11q loss 116 (40%) 176 0.00024816 0.19 0.23681 1 0.96616 1 0.55848 1 0.10838 1 0.55095 1 0.97852 1 0.21741 1 0.81346 1 0.36005 1 12p loss 45 (15%) 247 0.25634 1 0.063576 1 0.72537 1 0.42228 1 0.083151 1 0.65928 1 0.91209 1 0.67788 1 0.51858 1 0.63089 1 12q loss 51 (17%) 241 0.14159 1 0.041412 1 0.83965 1 0.52584 1 0.089687 1 0.40259 1 0.71809 1 0.42902 1 0.9043 1 0.81275 1 13q loss 63 (22%) 229 0.10471 1 0.0051187 1 0.079384 1 0.6856 1 0.58889 1 0.032387 1 0.71925 1 0.38043 1 0.95731 1 0.28834 1 14q loss 92 (32%) 200 8.4417e-06 0.00654 0.75283 1 0.37683 1 0.73678 1 0.0051136 1 0.13621 1 0.4963 1 0.97393 1 0.22461 1 0.63402 1 15q loss 42 (14%) 250 5.143e-06 0.00399 0.18821 1 0.11295 1 0.11453 1 0.46055 1 0.10951 1 0.8278 1 0.32012 1 0.72102 1 0.12597 1 16p loss 58 (20%) 234 0.41597 1 0.1558 1 0.035047 1 0.31145 1 0.018139 1 0.78965 1 0.13613 1 0.21399 1 0.19758 1 0.30661 1 16q loss 86 (29%) 206 0.66272 1 0.38578 1 0.006973 1 0.41456 1 0.0070421 1 0.1471 1 0.074892 1 0.044111 1 0.14729 1 0.058307 1 17p loss 98 (34%) 194 0.67305 1 0.33456 1 0.75157 1 0.30211 1 0.2305 1 0.3045 1 0.87025 1 0.42173 1 0.42286 1 0.60936 1 17q loss 47 (16%) 245 0.14251 1 0.86426 1 0.22661 1 0.43197 1 0.9324 1 0.74376 1 0.3784 1 0.73274 1 0.75334 1 0.69674 1 18p loss 84 (29%) 208 0.2301 1 0.65133 1 0.46205 1 0.84257 1 0.011112 1 0.24103 1 0.97787 1 0.48918 1 0.52878 1 0.69336 1 18q loss 79 (27%) 213 0.5832 1 0.73496 1 0.48439 1 0.77949 1 0.49133 1 0.67451 1 0.73482 1 0.27023 1 0.9122 1 0.67386 1 19p loss 61 (21%) 231 0.036151 1 0.21231 1 0.78213 1 0.038455 1 0.061119 1 0.53564 1 0.36766 1 0.68734 1 0.14428 1 0.41979 1 19q loss 58 (20%) 234 0.075318 1 0.078255 1 0.93811 1 0.025634 1 0.095023 1 0.6482 1 0.59269 1 0.68507 1 0.39131 1 0.37101 1 20p loss 18 (6%) 274 0.4676 1 0.85172 1 0.27372 1 0.21995 1 0.8953 1 0.69878 1 0.12462 1 0.26762 1 0.14706 1 0.20358 1 20q loss 7 (2%) 285 0.29997 1 0.43721 1 NA NA NA NA 0.73927 1 0.080801 1 0.5281 1 0.89773 1 0.27675 1 0.18133 1 21q loss 58 (20%) 234 0.53569 1 0.3885 1 0.42033 1 0.59938 1 0.50274 1 0.25298 1 0.13402 1 0.081955 1 0.042226 1 0.3051 1 22q loss 31 (11%) 261 0.49625 1 0.32261 1 0.97832 1 1 1 0.72636 1 0.86465 1 0.21232 1 0.95459 1 0.94214 1 0.88029 1 xq loss 73 (25%) 219 0.0018446 1 4.7742e-06 0.00371 0.19791 1 0.046712 1 0.0065779 1 0.010159 1 0.01574 1 0.56976 1 0.17574 1 0.88696 1