Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.028 0.195 -9999.0 0.0 -0.564 28.0 28.0 MAP3K8 0.001 0.068 -9999.0 0.0 -0.327 11.0 11.0 FOS -0.039 0.199 -9999.0 0.0 -0.577 29.0 29.0 PRKCA -0.004 0.084 -9999.0 0.0 -0.381 13.0 13.0 PTPN7 -0.036 0.133 -9999.0 0.0 -0.37 37.0 37.0 HRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.043 0.138 -9999.0 0.0 -0.354 44.0 44.0 NRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.041 0.194 -9999.0 0.0 -0.614 26.0 26.0 MAP2K1 -0.025 0.147 -9999.0 0.0 -0.393 35.0 35.0 ELK1 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.029 0.141 -9999.0 0.0 -0.375 37.0 37.0 mol:GTP 0.0 0.0 -9999.0 0.0 -0.003 6.0 6.0 MAPK1 -0.041 0.194 -9999.0 0.0 -0.599 27.0 27.0 RAF1 -0.027 0.138 -9999.0 0.0 -0.377 35.0 35.0 KRAS 0.013 0.016 -9999.0 0.0 -0.248 1.0 1.0