Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.017	0.12	0.299	1.0	-0.448	15.0	16.0
IHH	0.031	0.052	0.144	5.0	-0.134	20.0	25.0
SHH Np/Cholesterol/GAS1	0.015	0.029	-9999.0	0.0	-0.175	5.0	5.0
LRPAP1	0.027	0.006	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.015	0.028	0.175	5.0	-9999.0	0.0	5.0
SMO/beta Arrestin2	0.005	0.137	-9999.0	0.0	-0.386	14.0	14.0
SMO	-0.016	0.126	-9999.0	0.0	-0.388	17.0	17.0
AKT1	-0.002	0.102	-9999.0	0.0	-0.381	11.0	11.0
ARRB2	0.026	0.009	0.121	1.0	-9999.0	0.0	1.0
BOC	0.019	0.07	-9999.0	0.0	-0.331	10.0	10.0
ADRBK1	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.016	0.125	-9999.0	0.0	-0.382	17.0	17.0
STIL	0.02	0.089	0.188	34.0	-0.236	15.0	49.0
DHH N/PTCH2	0.032	0.071	0.176	2.0	-0.231	17.0	19.0
DHH N/PTCH1	0.021	0.113	0.208	1.0	-0.287	28.0	29.0
PIK3CA	0.022	0.043	-9999.0	0.0	-0.331	4.0	4.0
DHH	0.02	0.083	0.121	30.0	-0.331	13.0	43.0
PTHLH	-0.003	0.177	0.302	1.0	-0.615	19.0	20.0
determination of left/right symmetry	-0.016	0.125	-9999.0	0.0	-0.382	17.0	17.0
PIK3R1	0.024	0.031	-9999.0	0.0	-0.331	2.0	2.0
skeletal system development	-0.003	0.176	0.302	1.0	-0.609	19.0	20.0
IHH N/Hhip	0.043	0.041	0.188	2.0	-0.088	1.0	3.0
DHH N/Hhip	0.036	0.066	0.176	4.0	-0.232	13.0	17.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.016	0.125	-9999.0	0.0	-0.382	17.0	17.0
pancreas development	0.02	0.033	0.121	18.0	-9999.0	0.0	18.0
HHAT	0.019	0.048	-9999.0	0.0	-0.331	5.0	5.0
PI3K	0.033	0.043	-9999.0	0.0	-0.269	5.0	5.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.022	0.038	-9999.0	0.0	-0.331	3.0	3.0
somite specification	-0.016	0.125	-9999.0	0.0	-0.382	17.0	17.0
SHH Np/Cholesterol/PTCH1	0.01	0.07	-9999.0	0.0	-0.244	15.0	15.0
SHH Np/Cholesterol/PTCH2	0.017	0.034	0.157	2.0	-0.178	6.0	8.0
SHH Np/Cholesterol/Megalin	-0.007	0.108	0.193	14.0	-0.18	68.0	82.0
SHH	-0.012	0.027	-9999.0	0.0	-0.235	3.0	3.0
catabolic process	0.01	0.106	-9999.0	0.0	-0.358	20.0	20.0
SMO/Vitamin D3	0.006	0.104	0.259	5.0	-0.289	18.0	23.0
SHH Np/Cholesterol/Hhip	0.015	0.037	0.157	6.0	-0.175	3.0	9.0
LRP2	-0.047	0.18	0.121	80.0	-0.331	78.0	158.0
receptor-mediated endocytosis	-0.033	0.129	0.244	2.0	-0.325	28.0	30.0
SHH Np/Cholesterol/BOC	0.016	0.046	0.2	1.0	-0.194	10.0	11.0
SHH Np/Cholesterol/CDO	0.014	0.031	-9999.0	0.0	-0.178	6.0	6.0
mesenchymal cell differentiation	-0.015	0.036	0.174	3.0	-0.155	6.0	9.0
mol:Vitamin D3	0.037	0.1	0.219	37.0	-0.245	15.0	52.0
IHH N/PTCH2	0.037	0.051	0.199	1.0	-0.252	4.0	5.0
CDON	0.021	0.038	-9999.0	0.0	-0.331	3.0	3.0
IHH N/PTCH1	0.021	0.111	0.231	1.0	-0.351	21.0	22.0
Megalin/LRPAP1	-0.018	0.135	-9999.0	0.0	-0.231	78.0	78.0
PTCH2	0.024	0.045	-9999.0	0.0	-0.331	4.0	4.0
SHH Np/Cholesterol	0.01	0.02	-9999.0	0.0	-0.175	3.0	3.0
PTCH1	0.01	0.106	-9999.0	0.0	-0.359	20.0	20.0
HHIP	0.02	0.033	0.121	18.0	-9999.0	0.0	18.0