Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.099 0.216 48.0 -9999.0 0.0 48.0 KIRREL 0.002 0.052 -9999.0 0.0 -0.292 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.099 -9999.0 0.0 -0.216 48.0 48.0 PLCG1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.019 0.121 -9999.0 0.0 -0.217 55.0 55.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.094 -9999.0 0.0 -0.259 13.0 13.0 FYN -0.038 0.107 0.2 12.0 -0.208 54.0 66.0 mol:Ca2+ -0.02 0.113 -9999.0 0.0 -0.216 48.0 48.0 mol:DAG -0.019 0.114 -9999.0 0.0 -0.217 48.0 48.0 NPHS2 -0.058 0.154 -9999.0 0.0 -0.378 50.0 50.0 mol:IP3 -0.019 0.114 -9999.0 0.0 -0.217 48.0 48.0 regulation of endocytosis -0.021 0.105 -9999.0 0.0 -0.197 52.0 52.0 Nephrin/NEPH1/podocin/Cholesterol -0.029 0.113 -9999.0 0.0 -0.214 56.0 56.0 establishment of cell polarity -0.021 0.099 -9999.0 0.0 -0.216 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.007 0.118 -9999.0 0.0 -0.291 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.107 -9999.0 0.0 -0.199 52.0 52.0 NPHS1 -0.041 0.121 -9999.0 0.0 -0.29 49.0 49.0 Nephrin/NEPH1/podocin -0.025 0.109 -9999.0 0.0 -0.207 56.0 56.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.019 0.115 -9999.0 0.0 -0.218 48.0 48.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.122 -9999.0 0.0 -0.218 54.0 54.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.042 0.106 0.207 12.0 -0.201 54.0 66.0 cytoskeleton organization -0.046 0.102 0.205 2.0 -0.298 13.0 15.0 Nephrin/NEPH1 -0.009 0.069 -9999.0 0.0 -0.145 45.0 45.0 Nephrin/NEPH1/ZO-1 -0.003 0.086 -9999.0 0.0 -0.217 15.0 15.0