Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.167 0.304 0.687 118.0 -9999.0 0.0 118.0 KIRREL -0.071 0.238 -9999.0 0.0 -0.841 42.0 42.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.167 0.305 -9999.0 0.0 -0.689 118.0 118.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.13 0.242 -9999.0 0.0 -0.537 118.0 118.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.076 0.196 -9999.0 0.0 -0.408 118.0 118.0 FYN -0.11 0.236 -9999.0 0.0 -0.508 118.0 118.0 mol:Ca2+ -0.129 0.239 -9999.0 0.0 -0.531 118.0 118.0 mol:DAG -0.129 0.24 -9999.0 0.0 -0.534 118.0 118.0 NPHS2 -0.017 0.052 -9999.0 0.0 -0.89 1.0 1.0 mol:IP3 -0.129 0.24 -9999.0 0.0 -0.534 118.0 118.0 regulation of endocytosis -0.115 0.214 -9999.0 0.0 -0.475 118.0 118.0 Nephrin/NEPH1/podocin/Cholesterol -0.132 0.245 -9999.0 0.0 -0.546 118.0 118.0 establishment of cell polarity -0.167 0.304 -9999.0 0.0 -0.687 118.0 118.0 Nephrin/NEPH1/podocin/NCK1-2 -0.119 0.223 -9999.0 0.0 -0.492 118.0 118.0 Nephrin/NEPH1/beta Arrestin2 -0.102 0.226 -9999.0 0.0 -0.482 118.0 118.0 NPHS1 -0.153 0.32 -9999.0 0.0 -0.823 90.0 90.0 Nephrin/NEPH1/podocin -0.124 0.231 -9999.0 0.0 -0.512 118.0 118.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.13 0.242 -9999.0 0.0 -0.537 118.0 118.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.13 0.242 -9999.0 0.0 -0.537 118.0 118.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.113 0.246 -9999.0 0.0 -0.512 122.0 122.0 cytoskeleton organization -0.101 0.256 -9999.0 0.0 -0.534 118.0 118.0 Nephrin/NEPH1 -0.127 0.236 -9999.0 0.0 -0.526 118.0 118.0 Nephrin/NEPH1/ZO-1 -0.138 0.255 -9999.0 0.0 -0.571 118.0 118.0