Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.099 0.245 0.529 112.0 -9999.0 0.0 112.0 KIRREL -0.044 0.193 -9999.0 0.0 -0.689 39.0 39.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.1 0.245 -9999.0 0.0 -0.53 112.0 112.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.055 0.204 -9999.0 0.0 -0.432 103.0 103.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.057 0.159 -9999.0 0.0 -0.351 101.0 101.0 FYN -0.062 0.196 0.271 25.0 -0.402 105.0 130.0 mol:Ca2+ -0.055 0.2 -9999.0 0.0 -0.426 102.0 102.0 mol:DAG -0.054 0.201 -9999.0 0.0 -0.428 102.0 102.0 NPHS2 -0.005 0.053 -9999.0 0.0 -0.734 1.0 1.0 mol:IP3 -0.054 0.201 -9999.0 0.0 -0.428 102.0 102.0 regulation of endocytosis -0.049 0.18 -9999.0 0.0 -0.383 101.0 101.0 Nephrin/NEPH1/podocin/Cholesterol -0.067 0.198 -9999.0 0.0 -0.427 105.0 105.0 establishment of cell polarity -0.099 0.245 -9999.0 0.0 -0.529 112.0 112.0 Nephrin/NEPH1/podocin/NCK1-2 -0.039 0.196 -9999.0 0.0 -0.4 102.0 102.0 Nephrin/NEPH1/beta Arrestin2 -0.048 0.183 -9999.0 0.0 -0.388 101.0 101.0 NPHS1 -0.103 0.26 -9999.0 0.0 -0.67 83.0 83.0 Nephrin/NEPH1/podocin -0.06 0.189 -9999.0 0.0 -0.405 105.0 105.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.054 0.203 -9999.0 0.0 -0.43 102.0 102.0 CD2AP 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.054 0.201 -9999.0 0.0 -0.429 101.0 101.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.077 0.196 0.277 21.0 -0.41 105.0 126.0 cytoskeleton organization -0.081 0.199 -9999.0 0.0 -0.451 100.0 100.0 Nephrin/NEPH1 -0.071 0.184 -9999.0 0.0 -0.39 112.0 112.0 Nephrin/NEPH1/ZO-1 -0.068 0.211 -9999.0 0.0 -0.449 106.0 106.0