Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.108 0.22 -9999.0 0.0 -0.424 130.0 130.0 MAP3K8 0.014 0.085 -9999.0 0.0 -0.634 8.0 8.0 FOS -0.077 0.174 0.288 3.0 -0.446 58.0 61.0 PRKCA -0.015 0.141 -9999.0 0.0 -0.673 21.0 21.0 PTPN7 -0.02 0.128 -9999.0 0.0 -0.669 16.0 16.0 HRAS 0.025 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.006 0.082 -9999.0 0.0 -0.675 5.0 5.0 NRAS 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.034 0.031 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.013 0.117 -9999.0 0.0 -0.474 20.0 20.0 MAP2K1 -0.021 0.137 -9999.0 0.0 -0.541 25.0 25.0 ELK1 0.012 0.025 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.016 0.126 -9999.0 0.0 -0.525 25.0 25.0 mol:GTP -0.002 0.004 -9999.0 0.0 -0.006 128.0 128.0 MAPK1 -0.099 0.198 -9999.0 0.0 -0.409 116.0 116.0 RAF1 -0.015 0.122 -9999.0 0.0 -0.512 25.0 25.0 KRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0