Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.039	0.155	0.303	1.0	-0.492	37.0	38.0
IHH	0.065	0.144	0.323	98.0	-0.2	33.0	131.0
SHH Np/Cholesterol/GAS1	-0.069	0.092	0.136	9.0	-0.172	199.0	208.0
LRPAP1	0.022	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.069	0.091	0.171	199.0	-0.135	9.0	208.0
SMO/beta Arrestin2	-0.028	0.157	-9999.0	0.0	-0.312	84.0	84.0
SMO	-0.041	0.155	-9999.0	0.0	-0.32	92.0	92.0
AKT1	-0.011	0.119	-9999.0	0.0	-0.441	20.0	20.0
ARRB2	0.021	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.002	0.08	-9999.0	0.0	-0.318	30.0	30.0
ADRBK1	0.022	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.04	0.153	-9999.0	0.0	-0.316	92.0	92.0
STIL	-0.001	0.12	0.245	28.0	-0.241	27.0	55.0
DHH N/PTCH2	0.0	0.089	-9999.0	0.0	-0.235	61.0	61.0
DHH N/PTCH1	-0.031	0.127	-9999.0	0.0	-0.297	42.0	42.0
PIK3CA	0.02	0.017	-9999.0	0.0	-0.318	1.0	1.0
DHH	-0.005	0.092	-9999.0	0.0	-0.318	40.0	40.0
PTHLH	-0.043	0.189	0.377	1.0	-0.519	36.0	37.0
determination of left/right symmetry	-0.04	0.153	-9999.0	0.0	-0.316	92.0	92.0
PIK3R1	0.019	0.031	-9999.0	0.0	-0.318	4.0	4.0
skeletal system development	-0.043	0.188	0.376	1.0	-0.515	36.0	37.0
IHH N/Hhip	0.029	0.149	0.238	112.0	-0.209	94.0	206.0
DHH N/Hhip	0.023	0.09	0.235	33.0	-0.217	44.0	77.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.04	0.153	-9999.0	0.0	-0.316	92.0	92.0
pancreas development	0.04	0.083	0.323	35.0	-0.317	4.0	39.0
HHAT	0.017	0.027	-9999.0	0.0	-0.318	3.0	3.0
PI3K	0.027	0.028	-9999.0	0.0	-0.223	5.0	5.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.18	0.166	-9999.0	0.0	-0.318	299.0	299.0
somite specification	-0.04	0.153	-9999.0	0.0	-0.316	92.0	92.0
SHH Np/Cholesterol/PTCH1	-0.011	0.108	0.271	5.0	-0.251	28.0	33.0
SHH Np/Cholesterol/PTCH2	0.019	0.059	0.262	5.0	-0.183	21.0	26.0
SHH Np/Cholesterol/Megalin	0.09	0.109	0.232	168.0	-0.148	3.0	171.0
SHH	0.008	0.072	0.187	56.0	-0.223	5.0	61.0
catabolic process	-0.025	0.126	-9999.0	0.0	-0.307	36.0	36.0
SMO/Vitamin D3	0.003	0.154	0.305	23.0	-0.302	27.0	50.0
SHH Np/Cholesterol/Hhip	0.036	0.071	0.232	39.0	-0.171	8.0	47.0
LRP2	0.127	0.144	0.323	177.0	-9999.0	0.0	177.0
receptor-mediated endocytosis	0.013	0.139	0.24	37.0	-0.304	21.0	58.0
SHH Np/Cholesterol/BOC	0.017	0.061	0.134	53.0	-0.182	25.0	78.0
SHH Np/Cholesterol/CDO	0.001	0.076	0.262	5.0	-0.175	57.0	62.0
mesenchymal cell differentiation	-0.036	0.07	0.17	8.0	-0.23	39.0	47.0
mol:Vitamin D3	0.017	0.139	0.313	27.0	-0.253	28.0	55.0
IHH N/PTCH2	0.005	0.144	0.208	93.0	-0.225	111.0	204.0
CDON	-0.03	0.121	-9999.0	0.0	-0.318	76.0	76.0
IHH N/PTCH1	-0.008	0.152	-9999.0	0.0	-0.248	100.0	100.0
Megalin/LRPAP1	0.1	0.097	0.235	170.0	-9999.0	0.0	170.0
PTCH2	0.006	0.074	-9999.0	0.0	-0.318	25.0	25.0
SHH Np/Cholesterol	0.012	0.027	-9999.0	0.0	-0.165	5.0	5.0
PTCH1	-0.025	0.126	-9999.0	0.0	-0.308	36.0	36.0
HHIP	0.04	0.083	0.323	35.0	-0.318	4.0	39.0