Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.102 0.205 -9999.0 0.0 -0.525 51.0 51.0 MAP3K8 0.006 0.038 -9999.0 0.0 -0.322 5.0 5.0 FOS -0.069 0.164 -9999.0 0.0 -0.476 45.0 45.0 PRKCA -0.013 0.079 -9999.0 0.0 -0.321 29.0 29.0 PTPN7 0.007 0.041 0.309 6.0 -9999.0 0.0 6.0 HRAS 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.012 0.078 -9999.0 0.0 -0.321 28.0 28.0 NRAS 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.018 0.035 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.034 0.137 -9999.0 0.0 -0.682 16.0 16.0 MAP2K1 -0.063 0.15 -9999.0 0.0 -0.409 64.0 64.0 ELK1 0.003 0.028 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.04 0.121 -9999.0 0.0 -0.362 54.0 54.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 172.0 172.0 MAPK1 -0.039 0.139 -9999.0 0.0 -0.6 21.0 21.0 RAF1 -0.041 0.127 -9999.0 0.0 -0.385 52.0 52.0 KRAS 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0