Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.109 0.173 0.349 19.0 -9999.0 0.0 19.0 KIRREL -0.035 0.128 -9999.0 0.0 -0.491 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.109 0.173 -9999.0 0.0 -0.35 19.0 19.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.078 0.144 -9999.0 0.0 -0.327 6.0 6.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.044 0.107 -9999.0 0.0 -0.306 3.0 3.0 FYN -0.073 0.13 -9999.0 0.0 -0.238 20.0 20.0 mol:Ca2+ -0.078 0.143 -9999.0 0.0 -0.325 6.0 6.0 mol:DAG -0.078 0.144 -9999.0 0.0 -0.326 6.0 6.0 NPHS2 -0.035 0.117 -9999.0 0.0 -0.517 3.0 3.0 mol:IP3 -0.078 0.144 -9999.0 0.0 -0.326 6.0 6.0 regulation of endocytosis -0.061 0.124 -9999.0 0.0 -0.414 2.0 2.0 Nephrin/NEPH1/podocin/Cholesterol -0.085 0.144 -9999.0 0.0 -0.269 20.0 20.0 establishment of cell polarity -0.109 0.173 -9999.0 0.0 -0.349 19.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 -0.063 0.133 -9999.0 0.0 -0.441 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 -0.061 0.125 -9999.0 0.0 -0.419 2.0 2.0 NPHS1 -0.128 0.221 -9999.0 0.0 -0.492 15.0 15.0 Nephrin/NEPH1/podocin -0.073 0.131 -9999.0 0.0 -0.239 20.0 20.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.078 0.144 -9999.0 0.0 -0.327 6.0 6.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.078 0.144 -9999.0 0.0 -0.315 7.0 7.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.095 0.151 -9999.0 0.0 -0.318 11.0 11.0 cytoskeleton organization -0.054 0.129 -9999.0 0.0 -0.353 4.0 4.0 Nephrin/NEPH1 -0.074 0.121 -9999.0 0.0 -0.242 19.0 19.0 Nephrin/NEPH1/ZO-1 -0.077 0.138 -9999.0 0.0 -0.269 19.0 19.0