Correlation between gene mutation status and molecular subtypes

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 151 genes and 8 molecular subtypes across 91 patients, 2 significant findings detected with P value < 0.05 and Q value < 0.25.

CTNNB1 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 151 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 2 significant findings detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Chi-square test	Chi-square test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
CTNNB1	14 (15%)	77	0.435 (1.00)	0.0574 (1.00)	0.000193 (0.223)	3.12e-05 (0.0359)	0.000643 (0.739)	0.361 (1.00)	0.00645 (1.00)	0.251 (1.00)
CLIC6	11 (12%)	80	0.933 (1.00)	0.862 (1.00)	0.285 (1.00)	1 (1.00)	0.311 (1.00)	0.314 (1.00)	0.342 (1.00)	0.458 (1.00)
NMU	10 (11%)	81	0.151 (1.00)	0.442 (1.00)	0.137 (1.00)	0.112 (1.00)	0.15 (1.00)	0.407 (1.00)	0.299 (1.00)	0.788 (1.00)
LPPR2	6 (7%)	85	0.671 (1.00)	0.559 (1.00)	0.246 (1.00)	0.198 (1.00)	0.475 (1.00)	0.711 (1.00)	0.467 (1.00)	0.336 (1.00)
CHDH	6 (7%)	85	0.138 (1.00)	0.193 (1.00)	0.888 (1.00)	0.488 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
C4ORF32	9 (10%)	82	0.874 (1.00)	0.494 (1.00)	0.165 (1.00)	0.568 (1.00)	0.563 (1.00)	1 (1.00)	0.118 (1.00)	0.724 (1.00)
SYT8	14 (15%)	77	0.897 (1.00)	0.555 (1.00)	0.677 (1.00)	0.656 (1.00)	1 (1.00)	0.728 (1.00)	0.837 (1.00)	0.291 (1.00)
RINL	19 (21%)	72	0.0471 (1.00)	0.567 (1.00)	0.13 (1.00)	0.128 (1.00)	0.409 (1.00)	0.737 (1.00)	0.234 (1.00)	1 (1.00)
OBSCN	29 (32%)	62	0.527 (1.00)	0.494 (1.00)	0.223 (1.00)	0.802 (1.00)	0.256 (1.00)	0.762 (1.00)	0.208 (1.00)	0.599 (1.00)
MAP1S	9 (10%)	82	0.305 (1.00)	0.254 (1.00)	0.174 (1.00)	1 (1.00)	0.9 (1.00)	0.878 (1.00)	0.808 (1.00)	0.788 (1.00)
GPRIN2	11 (12%)	80	0.576 (1.00)	0.746 (1.00)	0.734 (1.00)	0.181 (1.00)	0.468 (1.00)	0.275 (1.00)	0.331 (1.00)	0.376 (1.00)
ATP9B	5 (5%)	86	0.853 (1.00)	0.292 (1.00)	0.804 (1.00)	0.861 (1.00)	1 (1.00)	1 (1.00)	0.703 (1.00)	1 (1.00)
RREB1	11 (12%)	80	0.0932 (1.00)	0.606 (1.00)	0.547 (1.00)	0.352 (1.00)	1 (1.00)	0.444 (1.00)	0.89 (1.00)	0.601 (1.00)
IDUA	15 (16%)	76	0.25 (1.00)	0.517 (1.00)	0.489 (1.00)	0.672 (1.00)	0.15 (1.00)	1 (1.00)	0.253 (1.00)	1 (1.00)
RGS9BP	11 (12%)	80	0.351 (1.00)	0.715 (1.00)	1 (1.00)	0.821 (1.00)	0.451 (1.00)	0.79 (1.00)	0.685 (1.00)	0.799 (1.00)
WDR34	11 (12%)	80	0.753 (1.00)	0.823 (1.00)	0.965 (1.00)	0.634 (1.00)	0.617 (1.00)	0.239 (1.00)	0.906 (1.00)	0.178 (1.00)
NOTCH2	12 (13%)	79	0.333 (1.00)	0.573 (1.00)	1 (1.00)	0.644 (1.00)	0.11 (1.00)	0.877 (1.00)	0.181 (1.00)	0.458 (1.00)
TMEM189	12 (13%)	79	0.188 (1.00)	0.854 (1.00)	0.319 (1.00)	0.0878 (1.00)	0.306 (1.00)	0.692 (1.00)	0.376 (1.00)	0.554 (1.00)
TAF5	12 (13%)	79	0.408 (1.00)	0.666 (1.00)	1 (1.00)	0.499 (1.00)	0.393 (1.00)	0.0703 (1.00)	0.187 (1.00)	0.11 (1.00)
LRP11	9 (10%)	82	0.00701 (1.00)	0.373 (1.00)	1 (1.00)	0.549 (1.00)	0.594 (1.00)	0.64 (1.00)	0.679 (1.00)	1 (1.00)
FPGS	14 (15%)	77	0.262 (1.00)	0.515 (1.00)	0.0636 (1.00)	1 (1.00)	0.64 (1.00)	1 (1.00)	0.363 (1.00)	1 (1.00)
BAG1	6 (7%)	85	0.956 (1.00)	0.359 (1.00)	0.626 (1.00)	0.728 (1.00)	0.346 (1.00)	0.0804 (1.00)	0.186 (1.00)	0.163 (1.00)
FZD1	6 (7%)	85	0.424 (1.00)	0.333 (1.00)	0.612 (1.00)	0.113 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
TOR3A	25 (27%)	66	0.674 (1.00)	0.0628 (1.00)	0.447 (1.00)	0.0295 (1.00)	0.887 (1.00)	0.221 (1.00)	0.925 (1.00)	0.447 (1.00)
TMEM200C	6 (7%)	85	0.652 (1.00)	0.333 (1.00)	0.0137 (1.00)	0.358 (1.00)	1 (1.00)	1 (1.00)	0.597 (1.00)	1 (1.00)
ZNF517	33 (36%)	58	0.59 (1.00)	0.962 (1.00)	0.688 (1.00)	0.857 (1.00)	0.519 (1.00)	1 (1.00)	0.66 (1.00)	1 (1.00)
DMRT1	5 (5%)	86	0.635 (1.00)	0.24 (1.00)	0.21 (1.00)	0.0922 (1.00)	0.0209 (1.00)	0.00222 (1.00)	0.0623 (1.00)	0.00318 (1.00)
GLTPD2	19 (21%)	72	0.339 (1.00)	0.962 (1.00)	0.955 (1.00)	0.683 (1.00)	0.477 (1.00)	0.515 (1.00)	0.721 (1.00)	0.849 (1.00)
SEMA5B	16 (18%)	75	0.191 (1.00)	0.637 (1.00)	0.114 (1.00)	0.314 (1.00)	0.78 (1.00)	0.826 (1.00)	1 (1.00)	0.83 (1.00)
TNIP2	7 (8%)	84	0.589 (1.00)	0.293 (1.00)	0.708 (1.00)	0.597 (1.00)	0.846 (1.00)	0.303 (1.00)	1 (1.00)	0.213 (1.00)
HHIPL1	14 (15%)	77	0.134 (1.00)	0.961 (1.00)	0.314 (1.00)	0.845 (1.00)	0.0149 (1.00)	0.0376 (1.00)	0.0212 (1.00)	0.124 (1.00)
HECTD2	7 (8%)	84	0.746 (1.00)	0.388 (1.00)	0.392 (1.00)	0.415 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	1 (1.00)
ADAD2	15 (16%)	76	0.138 (1.00)	0.141 (1.00)	0.889 (1.00)	0.25 (1.00)	0.578 (1.00)	0.567 (1.00)	0.628 (1.00)	0.638 (1.00)
ZFPM1	48 (53%)	43	0.225 (1.00)	0.903 (1.00)	0.916 (1.00)	0.838 (1.00)	0.829 (1.00)	0.225 (1.00)	0.548 (1.00)	0.413 (1.00)
CLDN23	13 (14%)	78	0.207 (1.00)	0.361 (1.00)	0.0204 (1.00)	0.15 (1.00)	0.137 (1.00)	0.303 (1.00)	0.147 (1.00)	0.509 (1.00)
CCDC105	11 (12%)	80	0.0641 (1.00)	0.00159 (1.00)	0.882 (1.00)	0.121 (1.00)	0.363 (1.00)	0.0204 (1.00)	0.279 (1.00)	0.0166 (1.00)
DMKN	3 (3%)	88	0.688 (1.00)	0.333 (1.00)	0.612 (1.00)	0.113 (1.00)	0.00708 (1.00)	1 (1.00)	0.0103 (1.00)	1 (1.00)
NOL9	12 (13%)	79	0.469 (1.00)	0.647 (1.00)	0.295 (1.00)	0.225 (1.00)	0.812 (1.00)	0.692 (1.00)	0.903 (1.00)	0.554 (1.00)
C19ORF10	10 (11%)	81	0.638 (1.00)	0.16 (1.00)	0.124 (1.00)	0.00708 (1.00)	0.237 (1.00)	0.757 (1.00)	0.105 (1.00)	0.764 (1.00)
ZNF598	19 (21%)	72	0.427 (1.00)	0.414 (1.00)	0.777 (1.00)	0.93 (1.00)	0.787 (1.00)	0.836 (1.00)	0.68 (1.00)	0.638 (1.00)
THEM4	14 (15%)	77	0.00763 (1.00)	0.251 (1.00)	0.97 (1.00)	0.917 (1.00)	0.484 (1.00)	0.141 (1.00)	0.762 (1.00)	0.0872 (1.00)
LRIG1	32 (35%)	59	0.533 (1.00)	0.731 (1.00)	0.656 (1.00)	0.707 (1.00)	0.296 (1.00)	0.818 (1.00)	0.902 (1.00)	0.631 (1.00)
MUC5B	25 (27%)	66	0.759 (1.00)	0.248 (1.00)	0.337 (1.00)	0.291 (1.00)	0.655 (1.00)	0.927 (1.00)	0.485 (1.00)	0.873 (1.00)
CTGF	6 (7%)	85	0.632 (1.00)	0.397 (1.00)	0.754 (1.00)	0.728 (1.00)	0.277 (1.00)	0.199 (1.00)	0.423 (1.00)	0.163 (1.00)
AMDHD1	18 (20%)	73	0.0677 (1.00)	0.896 (1.00)	0.563 (1.00)	0.652 (1.00)	0.273 (1.00)	0.294 (1.00)	0.0186 (1.00)	0.394 (1.00)
RNF149	7 (8%)	84	0.768 (1.00)	0.56 (1.00)	0.888 (1.00)	0.762 (1.00)	0.0871 (1.00)	0.123 (1.00)	0.146 (1.00)	0.141 (1.00)
MSH3	5 (5%)	86	0.00899 (1.00)	0.592 (1.00)	0.0701 (1.00)	0.684 (1.00)	0.132 (1.00)	0.342 (1.00)	0.182 (1.00)	0.192 (1.00)
ALPPL2	8 (9%)	83	0.907 (1.00)	0.121 (1.00)	0.339 (1.00)	0.365 (1.00)	0.703 (1.00)	0.258 (1.00)	0.8 (1.00)	0.281 (1.00)
SNED1	7 (8%)	84	0.671 (1.00)	0.623 (1.00)	0.547 (1.00)	0.711 (1.00)	0.0417 (1.00)	0.862 (1.00)	0.0706 (1.00)	0.865 (1.00)
NOXA1	5 (5%)	86	0.284 (1.00)	0.371 (1.00)	0.347 (1.00)	0.258 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
OPRD1	26 (29%)	65	0.24 (1.00)	0.832 (1.00)	0.646 (1.00)	0.759 (1.00)	0.465 (1.00)	0.466 (1.00)	0.695 (1.00)	0.629 (1.00)
CCDC102A	26 (29%)	65	0.587 (1.00)	0.864 (1.00)	0.908 (1.00)	0.82 (1.00)	0.544 (1.00)	0.586 (1.00)	0.677 (1.00)	0.385 (1.00)
KCTD3	8 (9%)	83	0.11 (1.00)	0.0699 (1.00)	0.686 (1.00)	0.488 (1.00)	1 (1.00)	0.711 (1.00)	1 (1.00)	0.612 (1.00)
C1ORF106	16 (18%)	75	0.9 (1.00)	0.439 (1.00)	0.518 (1.00)	0.816 (1.00)	1 (1.00)	0.537 (1.00)	0.749 (1.00)	0.634 (1.00)
KCNK17	19 (21%)	72	0.135 (1.00)	0.0959 (1.00)	0.201 (1.00)	0.0117 (1.00)	1 (1.00)	0.278 (1.00)	0.881 (1.00)	0.497 (1.00)
LACTB	27 (30%)	64	0.0645 (1.00)	0.343 (1.00)	0.906 (1.00)	1 (1.00)	0.571 (1.00)	0.708 (1.00)	0.485 (1.00)	0.858 (1.00)
TRIOBP	24 (26%)	67	0.713 (1.00)	0.709 (1.00)	0.775 (1.00)	0.406 (1.00)	1 (1.00)	0.794 (1.00)	0.94 (1.00)	1 (1.00)
SARM1	14 (15%)	77	0.0196 (1.00)	0.471 (1.00)	0.836 (1.00)	0.908 (1.00)	0.468 (1.00)	0.615 (1.00)	0.331 (1.00)	0.0591 (1.00)
ERCC2	19 (21%)	72	0.0188 (1.00)	0.229 (1.00)	0.107 (1.00)	0.00307 (1.00)	0.166 (1.00)	0.0678 (1.00)	0.077 (1.00)	0.0388 (1.00)
NEFH	10 (11%)	81	0.167 (1.00)	0.382 (1.00)	0.234 (1.00)	1 (1.00)	0.491 (1.00)	0.661 (1.00)	0.625 (1.00)	0.764 (1.00)
KBTBD13	15 (16%)	76	0.344 (1.00)	0.467 (1.00)	0.765 (1.00)	0.101 (1.00)	0.731 (1.00)	0.737 (1.00)	0.493 (1.00)	0.859 (1.00)
IRX3	21 (23%)	70	0.315 (1.00)	0.538 (1.00)	0.241 (1.00)	0.456 (1.00)	0.307 (1.00)	0.766 (1.00)	0.141 (1.00)	1 (1.00)
MUC2	18 (20%)	73	0.829 (1.00)	0.0845 (1.00)	0.098 (1.00)	0.0889 (1.00)	0.179 (1.00)	0.0271 (1.00)	0.114 (1.00)	0.0432 (1.00)
GARS	35 (38%)	56	0.284 (1.00)	0.562 (1.00)	0.548 (1.00)	0.154 (1.00)	0.173 (1.00)	0.0436 (1.00)	0.123 (1.00)	0.0908 (1.00)
UQCRFS1	12 (13%)	79	0.885 (1.00)	0.429 (1.00)	0.822 (1.00)	0.544 (1.00)	0.36 (1.00)	0.0717 (1.00)	0.328 (1.00)	0.0653 (1.00)
ATXN1	14 (15%)	77	0.661 (1.00)	0.178 (1.00)	0.677 (1.00)	0.845 (1.00)	0.833 (1.00)	0.899 (1.00)	0.917 (1.00)	0.904 (1.00)
ZNF628	10 (11%)	81	0.0739 (1.00)	0.368 (1.00)	0.0703 (1.00)	0.059 (1.00)	0.0417 (1.00)	0.446 (1.00)	0.0433 (1.00)	0.406 (1.00)
DSPP	13 (14%)	78	0.694 (1.00)	0.175 (1.00)	0.867 (1.00)	0.917 (1.00)	0.833 (1.00)	0.586 (1.00)	0.448 (1.00)	0.492 (1.00)
ASPDH	19 (21%)	72	0.289 (1.00)	0.674 (1.00)	0.0774 (1.00)	0.0874 (1.00)	0.174 (1.00)	0.00171 (1.00)	0.0539 (1.00)	0.00136 (1.00)
CSGALNACT2	5 (5%)	86	0.312 (1.00)	0.0371 (1.00)	0.626 (1.00)	0.264 (1.00)	0.125 (1.00)	0.248 (1.00)	0.186 (1.00)	0.325 (1.00)
TPO	21 (23%)	70	0.297 (1.00)	0.102 (1.00)	0.25 (1.00)	0.249 (1.00)	0.276 (1.00)	1 (1.00)	0.172 (1.00)	0.705 (1.00)
KRTAP4-5	7 (8%)	84	0.262 (1.00)	0.115 (1.00)	0.722 (1.00)	0.88 (1.00)	0.855 (1.00)	0.306 (1.00)	0.547 (1.00)	0.336 (1.00)
GLTSCR2	8 (9%)	83	0.504 (1.00)	0.173 (1.00)	0.217 (1.00)	0.711 (1.00)	0.297 (1.00)	0.216 (1.00)	0.0706 (1.00)	0.342 (1.00)
PANK2	15 (16%)	76	0.725 (1.00)	0.802 (1.00)	0.779 (1.00)	0.724 (1.00)	1 (1.00)	0.748 (1.00)	1 (1.00)	0.509 (1.00)
RNF39	7 (8%)	84	0.416 (1.00)	0.139 (1.00)	0.0334 (1.00)	0.00798 (1.00)	0.0544 (1.00)	0.64 (1.00)	0.145 (1.00)	0.645 (1.00)
MAL2	23 (25%)	68	0.275 (1.00)	0.782 (1.00)	0.0202 (1.00)	1 (1.00)	0.425 (1.00)	0.687 (1.00)	0.782 (1.00)	0.849 (1.00)
ZAR1	19 (21%)	72	0.252 (1.00)	0.634 (1.00)	0.543 (1.00)	0.602 (1.00)	0.281 (1.00)	1 (1.00)	0.542 (1.00)	0.849 (1.00)
C16ORF3	8 (9%)	83	0.734 (1.00)	0.00275 (1.00)	0.43 (1.00)	1 (1.00)	0.656 (1.00)	1 (1.00)	0.645 (1.00)	1 (1.00)
KRTAP5-5	7 (8%)	84	0.505 (1.00)	0.564 (1.00)	0.515 (1.00)	1 (1.00)	0.591 (1.00)	0.537 (1.00)	0.703 (1.00)	0.834 (1.00)
CRIPAK	17 (19%)	74	0.378 (1.00)	0.566 (1.00)	0.163 (1.00)	0.815 (1.00)	0.87 (1.00)	1 (1.00)	0.705 (1.00)	1 (1.00)
C14ORF180	4 (4%)	87	0.626 (1.00)	0.0794 (1.00)	0.537 (1.00)	0.621 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.249 (1.00)
SPERT	5 (5%)	86	0.463 (1.00)	0.592 (1.00)	0.0316 (1.00)	0.128 (1.00)	0.132 (1.00)	0.342 (1.00)	0.182 (1.00)	0.192 (1.00)
TP53	17 (19%)	74	0.0173 (1.00)	0.519 (1.00)	0.00344 (1.00)	0.115 (1.00)	0.00268 (1.00)	0.07 (1.00)	0.00936 (1.00)	0.0373 (1.00)
B3GNT6	4 (4%)	87	0.32 (1.00)
BHLHE22	10 (11%)	81	0.0312 (1.00)	0.27 (1.00)	0.00963 (1.00)	0.3 (1.00)	0.684 (1.00)	0.89 (1.00)	0.831 (1.00)	1 (1.00)
RGMB	10 (11%)	81	0.186 (1.00)	0.831 (1.00)	0.935 (1.00)	0.363 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	1 (1.00)
APOE	8 (9%)	83	0.0848 (1.00)	0.342 (1.00)	0.124 (1.00)	0.471 (1.00)	0.297 (1.00)	0.446 (1.00)	0.0706 (1.00)	0.406 (1.00)
PCGF6	4 (4%)	87	0.497 (1.00)
MEN1	8 (9%)	83	0.384 (1.00)	0.0105 (1.00)	0.165 (1.00)	0.014 (1.00)	0.491 (1.00)	0.375 (1.00)	0.625 (1.00)	0.332 (1.00)
LZTR1	7 (8%)	84	0.241 (1.00)	0.305 (1.00)	0.055 (1.00)	0.44 (1.00)	0.213 (1.00)	0.152 (1.00)	0.358 (1.00)	0.553 (1.00)
RASIP1	11 (12%)	80	0.337 (1.00)	0.735 (1.00)	0.0442 (1.00)	0.155 (1.00)	0.0118 (1.00)	0.211 (1.00)	0.00128 (1.00)	0.199 (1.00)
ZC3H12D	6 (7%)	85	0.0274 (1.00)	0.864 (1.00)	0.804 (1.00)	0.32 (1.00)	0.422 (1.00)	0.303 (1.00)	0.499 (1.00)	0.063 (1.00)
TSC22D2	11 (12%)	80	0.372 (1.00)	0.275 (1.00)	0.936 (1.00)	0.694 (1.00)	1 (1.00)	0.514 (1.00)	1 (1.00)	0.465 (1.00)
COQ2	7 (8%)	84	0.081 (1.00)	0.691 (1.00)	0.528 (1.00)	0.488 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.724 (1.00)
DLEU7	6 (7%)	85	0.218 (1.00)	0.788 (1.00)	0.536 (1.00)	0.21 (1.00)	0.409 (1.00)	1 (1.00)	0.444 (1.00)	1 (1.00)
FAM46A	4 (4%)	87	0.709 (1.00)	0.874 (1.00)	0.877 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
JMJD4	6 (7%)	85	0.634 (1.00)	0.177 (1.00)	0.331 (1.00)	0.44 (1.00)	0.846 (1.00)	0.822 (1.00)	1 (1.00)	0.834 (1.00)
DOK7	7 (8%)	84	0.609 (1.00)	0.373 (1.00)	1 (1.00)	1 (1.00)	0.882 (1.00)	0.0198 (1.00)	0.771 (1.00)	0.02 (1.00)
KNDC1	16 (18%)	75	0.775 (1.00)	0.0847 (1.00)	0.554 (1.00)	0.601 (1.00)	0.593 (1.00)	0.588 (1.00)	0.588 (1.00)	0.724 (1.00)
SIX6	3 (3%)	88	0.00409 (1.00)	0.0715 (1.00)	0.00478 (1.00)	0.0202 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
PDCD6	5 (5%)	86	0.0684 (1.00)	0.482 (1.00)	0.348 (1.00)	0.379 (1.00)	0.422 (1.00)	0.822 (1.00)	0.499 (1.00)	0.553 (1.00)
HNRNPCL1	4 (4%)	87	0.292 (1.00)
ATP6V0E2	4 (4%)	87	0.724 (1.00)	0.725 (1.00)	0.638 (1.00)	0.467 (1.00)	0.0883 (1.00)	0.435 (1.00)	0.133 (1.00)	0.455 (1.00)
HES3	7 (8%)	84	0.505 (1.00)	0.794 (1.00)	0.515 (1.00)	0.44 (1.00)	0.166 (1.00)	1 (1.00)	0.299 (1.00)	1 (1.00)
AATK	9 (10%)	82	0.518 (1.00)	0.32 (1.00)	0.725 (1.00)	0.279 (1.00)	1 (1.00)	0.862 (1.00)	1 (1.00)	0.747 (1.00)
FANK1	4 (4%)	87	0.863 (1.00)	0.496 (1.00)	0.877 (1.00)	0.781 (1.00)	0.781 (1.00)	0.229 (1.00)	0.796 (1.00)	0.249 (1.00)
FEZ2	5 (5%)	86	0.809 (1.00)	0.982 (1.00)	0.485 (1.00)	0.506 (1.00)	0.277 (1.00)	0.537 (1.00)	0.423 (1.00)	0.163 (1.00)
HSD17B1	5 (5%)	86	0.809 (1.00)	0.246 (1.00)	1 (1.00)	0.176 (1.00)	0.591 (1.00)	1 (1.00)	0.703 (1.00)	0.432 (1.00)
PRKAR1A	7 (8%)	84	0.609 (1.00)	0.794 (1.00)	0.0594 (1.00)	0.471 (1.00)	0.523 (1.00)	0.64 (1.00)	0.219 (1.00)	0.645 (1.00)
ATOH8	4 (4%)	87	0.626 (1.00)	0.7 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.229 (1.00)	1 (1.00)	0.249 (1.00)
BTBD11	9 (10%)	82	0.498 (1.00)	0.872 (1.00)	0.267 (1.00)	0.278 (1.00)	0.703 (1.00)	0.877 (1.00)	0.8 (1.00)	0.875 (1.00)
KANK3	6 (7%)	85	0.0378 (1.00)	0.532 (1.00)	0.048 (1.00)	0.0108 (1.00)	0.0573 (1.00)	1 (1.00)	0.101 (1.00)	1 (1.00)
PAQR4	3 (3%)	88	0.872 (1.00)	0.874 (1.00)	0.877 (1.00)	1 (1.00)	0.781 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
NOM1	7 (8%)	84	0.768 (1.00)	0.691 (1.00)	0.615 (1.00)	0.88 (1.00)	0.855 (1.00)	1 (1.00)	0.547 (1.00)	1 (1.00)
PLIN5	6 (7%)	85	0.152 (1.00)	0.505 (1.00)	0.888 (1.00)	0.488 (1.00)	0.326 (1.00)	0.0402 (1.00)	0.146 (1.00)	0.0391 (1.00)
CD320	5 (5%)	86	0.72 (1.00)	0.564 (1.00)	0.708 (1.00)	1 (1.00)	0.213 (1.00)	0.152 (1.00)	0.0756 (1.00)	0.128 (1.00)
AVL9	6 (7%)	85	0.25 (1.00)	0.381 (1.00)	0.908 (1.00)	0.813 (1.00)	1 (1.00)	0.591 (1.00)	1 (1.00)	0.617 (1.00)
ASB16	10 (11%)	81	0.808 (1.00)	0.947 (1.00)	0.555 (1.00)	0.88 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
SCRT1	6 (7%)	85	0.616 (1.00)	0.345 (1.00)	0.761 (1.00)	1 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.724 (1.00)
FOXQ1	4 (4%)	87	0.0765 (1.00)	0.0866 (1.00)	1 (1.00)	0.781 (1.00)	0.586 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
NPTX1	6 (7%)	85	0.101 (1.00)	0.494 (1.00)	0.615 (1.00)	0.313 (1.00)	0.398 (1.00)	0.306 (1.00)	0.399 (1.00)	0.0522 (1.00)
ZNF285	3 (3%)	88	0.526 (1.00)
PTPLA	6 (7%)	85	0.243 (1.00)	0.359 (1.00)	0.708 (1.00)	0.597 (1.00)	1 (1.00)	1 (1.00)	0.703 (1.00)	1 (1.00)
PRSS27	4 (4%)	87	0.439 (1.00)	0.592 (1.00)	0.261 (1.00)	0.128 (1.00)	0.185 (1.00)	1 (1.00)	0.254 (1.00)	1 (1.00)
LRRN4	4 (4%)	87	0.838 (1.00)	0.51 (1.00)	0.76 (1.00)	1 (1.00)	0.409 (1.00)	0.342 (1.00)	0.444 (1.00)	1 (1.00)
EP400	4 (4%)	87	0.872 (1.00)	0.725 (1.00)	0.448 (1.00)	0.684 (1.00)	1 (1.00)	0.786 (1.00)	1 (1.00)	1 (1.00)
LTK	4 (4%)	87	0.863 (1.00)
CCDC96	4 (4%)	87	0.103 (1.00)	0.592 (1.00)	1 (1.00)	0.684 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
PCMTD1	4 (4%)	87	0.257 (1.00)	0.21 (1.00)	0.348 (1.00)	0.379 (1.00)	1 (1.00)	0.786 (1.00)	1 (1.00)	1 (1.00)
GLI3	8 (9%)	83	0.731 (1.00)	0.217 (1.00)	0.643 (1.00)	0.146 (1.00)	0.346 (1.00)	0.64 (1.00)	0.589 (1.00)	1 (1.00)
MN1	9 (10%)	82	0.767 (1.00)	0.264 (1.00)	0.882 (1.00)	0.898 (1.00)	0.393 (1.00)	0.258 (1.00)	0.267 (1.00)	0.281 (1.00)
C9ORF66	7 (8%)	84	0.51 (1.00)	0.947 (1.00)	0.761 (1.00)	0.488 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	0.724 (1.00)
MADCAM1	5 (5%)	86	0.0541 (1.00)	0.864 (1.00)	0.348 (1.00)	0.379 (1.00)	0.422 (1.00)	0.303 (1.00)	0.499 (1.00)	0.213 (1.00)
BMP8A	3 (3%)	88	0.387 (1.00)	0.661 (1.00)	1 (1.00)	0.781 (1.00)	1 (1.00)	1 (1.00)	0.597 (1.00)	0.538 (1.00)
ODF3L2	3 (3%)	88	0.872 (1.00)	0.661 (1.00)	0.775 (1.00)	0.781 (1.00)	0.781 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
QRICH2	4 (4%)	87	0.724 (1.00)	0.635 (1.00)	0.288 (1.00)	0.561 (1.00)	0.816 (1.00)	0.591 (1.00)	0.677 (1.00)	0.617 (1.00)
KRTAP10-7	5 (5%)	86	0.694 (1.00)	0.359 (1.00)	0.804 (1.00)	0.861 (1.00)	0.0163 (1.00)	0.199 (1.00)	0.0264 (1.00)	0.267 (1.00)
IDI1	5 (5%)	86	0.573 (1.00)	0.564 (1.00)	0.667 (1.00)	0.861 (1.00)	1 (1.00)	0.407 (1.00)	0.845 (1.00)	0.432 (1.00)
IER5	3 (3%)	88	0.237 (1.00)
PRR21	6 (7%)	85	0.585 (1.00)	0.684 (1.00)	0.754 (1.00)	0.728 (1.00)	1 (1.00)	0.537 (1.00)	0.845 (1.00)	0.834 (1.00)
ARRDC4	7 (8%)	84	0.465 (1.00)	0.334 (1.00)	0.329 (1.00)	0.165 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.612 (1.00)
RNF135	4 (4%)	87	0.709 (1.00)	0.344 (1.00)	0.296 (1.00)	0.621 (1.00)	0.781 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
DAXX	4 (4%)	87	0.0325 (1.00)	0.21 (1.00)	0.261 (1.00)	0.0362 (1.00)	0.409 (1.00)	1 (1.00)	0.444 (1.00)	1 (1.00)
VARS	8 (9%)	83	0.749 (1.00)	0.931 (1.00)	0.227 (1.00)	0.278 (1.00)	0.311 (1.00)	1 (1.00)	0.158 (1.00)	0.68 (1.00)
GPR20	4 (4%)	87	0.626 (1.00)	0.7 (1.00)	0.249 (1.00)	1 (1.00)	0.434 (1.00)	1 (1.00)	0.597 (1.00)	1 (1.00)
SAMD11	3 (3%)	88	0.433 (1.00)
DMWD	4 (4%)	87	0.254 (1.00)	0.788 (1.00)	0.38 (1.00)	0.813 (1.00)	1 (1.00)	1 (1.00)	0.254 (1.00)	1 (1.00)
KISS1R	3 (3%)	88	0.872 (1.00)
PLEC	17 (19%)	74	0.534 (1.00)	0.75 (1.00)	0.222 (1.00)	0.76 (1.00)	0.689 (1.00)	0.537 (1.00)	1 (1.00)	0.634 (1.00)
FAM110C	3 (3%)	88	0.723 (1.00)	0.7 (1.00)	0.465 (1.00)	0.468 (1.00)	1 (1.00)	0.229 (1.00)	1 (1.00)	0.249 (1.00)
RCCD1	5 (5%)	86	0.694 (1.00)	0.371 (1.00)	0.403 (1.00)	0.621 (1.00)	0.781 (1.00)	1 (1.00)	0.796 (1.00)	0.538 (1.00)

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.933 (Chi-square test), Q value = 1

Table S1. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CLIC6 MUTATED	5	3	1	1	1
CLIC6 WILD-TYPE	27	20	14	9	8

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.862 (Chi-square test), Q value = 1

Table S2. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CLIC6 MUTATED	1	1	2	3	1
CLIC6 WILD-TYPE	17	10	19	15	10

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CLIC6 MUTATED	2	2	0	4
CLIC6 WILD-TYPE	22	12	17	19

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CLIC6 MUTATED	2	4	2
CLIC6 WILD-TYPE	21	29	20

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CLIC6 MUTATED	2	3	3
CLIC6 WILD-TYPE	35	13	23

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CLIC6 MUTATED	3	2	3
CLIC6 WILD-TYPE	23	8	40

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CLIC6 MUTATED	2	3	3
CLIC6 WILD-TYPE	36	15	20

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CLIC6 MUTATED	3	2	3
CLIC6 WILD-TYPE	38	9	24

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.151 (Chi-square test), Q value = 1

Table S9. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NMU MUTATED	3	2	4	0	0
NMU WILD-TYPE	29	21	11	10	9

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.442 (Chi-square test), Q value = 1

Table S10. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NMU MUTATED	1	2	4	2	0
NMU WILD-TYPE	17	9	17	16	11

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NMU MUTATED	1	4	1	2
NMU WILD-TYPE	23	10	16	21

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NMU MUTATED	1	2	5
NMU WILD-TYPE	22	31	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NMU MUTATED	7	1	1
NMU WILD-TYPE	30	15	25

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NMU MUTATED	2	0	7
NMU WILD-TYPE	24	10	36

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NMU MUTATED	7	1	1
NMU WILD-TYPE	31	17	22

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NMU MUTATED	6	1	2
NMU WILD-TYPE	35	10	25

'LPPR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Chi-square test), Q value = 1

Table S17. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LPPR2 MUTATED	1	1	2	1	1
LPPR2 WILD-TYPE	31	22	13	9	8

'LPPR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.559 (Chi-square test), Q value = 1

Table S18. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LPPR2 MUTATED	0	1	3	1	1
LPPR2 WILD-TYPE	18	10	18	17	10

'LPPR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S19. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LPPR2 MUTATED	0	1	2	3
LPPR2 WILD-TYPE	24	13	15	20

'LPPR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 1

Table S20. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LPPR2 MUTATED	0	3	3
LPPR2 WILD-TYPE	23	30	19

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LPPR2 MUTATED	4	0	2
LPPR2 WILD-TYPE	33	16	24

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LPPR2 MUTATED	1	1	4
LPPR2 WILD-TYPE	25	9	39

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LPPR2 MUTATED	4	0	2
LPPR2 WILD-TYPE	34	18	21

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LPPR2 MUTATED	3	2	1
LPPR2 WILD-TYPE	38	9	26

'CHDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Chi-square test), Q value = 1

Table S25. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CHDH MUTATED	1	0	3	1	1
CHDH WILD-TYPE	31	23	12	9	8

'CHDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.193 (Chi-square test), Q value = 1

Table S26. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CHDH MUTATED	0	1	3	0	2
CHDH WILD-TYPE	18	10	18	18	9

'CHDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S27. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CHDH MUTATED	1	1	2	2
CHDH WILD-TYPE	23	13	15	21

'CHDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S28. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CHDH MUTATED	1	2	3
CHDH WILD-TYPE	22	31	19

'CHDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S29. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	34	15	24

'CHDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S30. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CHDH MUTATED	2	1	3
CHDH WILD-TYPE	24	9	40

'CHDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	35	17	21

'CHDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	38	10	25

'C4ORF32 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S33. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C4ORF32 MUTATED	4	1	2	1	1
C4ORF32 WILD-TYPE	28	22	13	9	8

'C4ORF32 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S34. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C4ORF32 MUTATED	3	0	1	1	1
C4ORF32 WILD-TYPE	15	11	20	17	10

'C4ORF32 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S35. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C4ORF32 MUTATED	4	1	1	0
C4ORF32 WILD-TYPE	20	13	16	23

'C4ORF32 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S36. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C4ORF32 MUTATED	3	2	1
C4ORF32 WILD-TYPE	20	31	21

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S37. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C4ORF32 MUTATED	3	2	1
C4ORF32 WILD-TYPE	34	14	25

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S38. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C4ORF32 MUTATED	2	0	4
C4ORF32 WILD-TYPE	24	10	39

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C4ORF32 MUTATED	3	3	0
C4ORF32 WILD-TYPE	35	15	23

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C4ORF32 MUTATED	3	0	3
C4ORF32 WILD-TYPE	38	11	24

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.897 (Chi-square test), Q value = 1

Table S41. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SYT8 MUTATED	5	5	2	1	1
SYT8 WILD-TYPE	27	18	13	9	8

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.555 (Chi-square test), Q value = 1

Table S42. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SYT8 MUTATED	1	3	3	3	1
SYT8 WILD-TYPE	17	8	18	15	10

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S43. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SYT8 MUTATED	2	3	2	4
SYT8 WILD-TYPE	22	11	15	19

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S44. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SYT8 MUTATED	2	5	4
SYT8 WILD-TYPE	21	28	18

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S45. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SYT8 MUTATED	5	2	4
SYT8 WILD-TYPE	32	14	22

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S46. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SYT8 MUTATED	4	2	5
SYT8 WILD-TYPE	22	8	38

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S47. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SYT8 MUTATED	5	2	4
SYT8 WILD-TYPE	33	16	19

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S48. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SYT8 MUTATED	4	3	4
SYT8 WILD-TYPE	37	8	23

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0471 (Chi-square test), Q value = 1

Table S49. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RINL MUTATED	12	2	3	2	0
RINL WILD-TYPE	20	21	12	8	9

Figure S1. Get High-res Image Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.567 (Chi-square test), Q value = 1

Table S50. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RINL MUTATED	6	2	4	3	1
RINL WILD-TYPE	12	9	17	15	10

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S51. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RINL MUTATED	8	4	2	2
RINL WILD-TYPE	16	10	15	21

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S52. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RINL MUTATED	8	4	4
RINL WILD-TYPE	15	29	18

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S53. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RINL MUTATED	9	4	3
RINL WILD-TYPE	28	12	23

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S54. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RINL MUTATED	5	1	10
RINL WILD-TYPE	21	9	33

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S55. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RINL MUTATED	9	5	2
RINL WILD-TYPE	29	13	21

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S56. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RINL MUTATED	8	2	6
RINL WILD-TYPE	33	9	21

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.527 (Chi-square test), Q value = 1

Table S57. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
OBSCN MUTATED	12	8	2	4	3
OBSCN WILD-TYPE	20	15	13	6	6

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S58. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
OBSCN MUTATED	5	6	5	6	4
OBSCN WILD-TYPE	13	5	16	12	7

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S59. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
OBSCN MUTATED	10	3	8	5
OBSCN WILD-TYPE	14	11	9	18

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S60. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
OBSCN MUTATED	8	12	6
OBSCN WILD-TYPE	15	21	16

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S61. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
OBSCN MUTATED	10	8	8
OBSCN WILD-TYPE	27	8	18

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S62. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
OBSCN MUTATED	10	3	13
OBSCN WILD-TYPE	16	7	30

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S63. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
OBSCN MUTATED	10	9	7
OBSCN WILD-TYPE	28	9	16

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S64. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
OBSCN MUTATED	12	3	11
OBSCN WILD-TYPE	29	8	16

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Chi-square test), Q value = 1

Table S65. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MAP1S MUTATED	1	2	3	1	2
MAP1S WILD-TYPE	31	21	12	9	7

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.254 (Chi-square test), Q value = 1

Table S66. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MAP1S MUTATED	1	3	2	3	0
MAP1S WILD-TYPE	17	8	19	15	11

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S67. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MAP1S MUTATED	2	3	0	4
MAP1S WILD-TYPE	22	11	17	19

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S68. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MAP1S MUTATED	3	4	2
MAP1S WILD-TYPE	20	29	20

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S69. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MAP1S MUTATED	5	1	3
MAP1S WILD-TYPE	32	15	23

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S70. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MAP1S MUTATED	2	1	6
MAP1S WILD-TYPE	24	9	37

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S71. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MAP1S MUTATED	5	1	3
MAP1S WILD-TYPE	33	17	20

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S72. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MAP1S MUTATED	6	1	2
MAP1S WILD-TYPE	35	10	25

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.576 (Chi-square test), Q value = 1

Table S73. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GPRIN2 MUTATED	3	3	3	2	0
GPRIN2 WILD-TYPE	29	20	12	8	9

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.746 (Chi-square test), Q value = 1

Table S74. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GPRIN2 MUTATED	2	1	4	1	1
GPRIN2 WILD-TYPE	16	10	17	17	10

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S75. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GPRIN2 MUTATED	2	2	3	2
GPRIN2 WILD-TYPE	22	12	14	21

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S76. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GPRIN2 MUTATED	2	2	5
GPRIN2 WILD-TYPE	21	31	17

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S77. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GPRIN2 MUTATED	3	3	3
GPRIN2 WILD-TYPE	34	13	23

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S78. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GPRIN2 MUTATED	5	1	3
GPRIN2 WILD-TYPE	21	9	40

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S79. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GPRIN2 MUTATED	3	4	2
GPRIN2 WILD-TYPE	35	14	21

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S80. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GPRIN2 MUTATED	3	1	5
GPRIN2 WILD-TYPE	38	10	22

'ATP9B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.853 (Chi-square test), Q value = 1

Table S81. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATP9B MUTATED	1	1	1	1	1
ATP9B WILD-TYPE	31	22	14	9	8

'ATP9B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Chi-square test), Q value = 1

Table S82. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATP9B MUTATED	0	1	3	0	1
ATP9B WILD-TYPE	18	10	18	18	10

'ATP9B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S83. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATP9B MUTATED	1	1	2	1
ATP9B WILD-TYPE	23	13	15	22

'ATP9B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S84. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATP9B MUTATED	1	2	2
ATP9B WILD-TYPE	22	31	20

'ATP9B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S85. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATP9B MUTATED	2	1	2
ATP9B WILD-TYPE	35	15	24

'ATP9B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S86. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATP9B MUTATED	2	0	3
ATP9B WILD-TYPE	24	10	40

'ATP9B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S87. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATP9B MUTATED	2	2	1
ATP9B WILD-TYPE	36	16	22

'ATP9B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S88. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATP9B MUTATED	3	0	2
ATP9B WILD-TYPE	38	11	25

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0932 (Chi-square test), Q value = 1

Table S89. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RREB1 MUTATED	8	1	1	0	1
RREB1 WILD-TYPE	24	22	14	10	8

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Chi-square test), Q value = 1

Table S90. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RREB1 MUTATED	3	2	1	1	1
RREB1 WILD-TYPE	15	9	20	17	10

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S91. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RREB1 MUTATED	4	1	1	1
RREB1 WILD-TYPE	20	13	16	22

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S92. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RREB1 MUTATED	4	2	1
RREB1 WILD-TYPE	19	31	21

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S93. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RREB1 MUTATED	4	1	3
RREB1 WILD-TYPE	33	15	23

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S94. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RREB1 MUTATED	2	2	4
RREB1 WILD-TYPE	24	8	39

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S95. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RREB1 MUTATED	4	1	3
RREB1 WILD-TYPE	34	17	20

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S96. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RREB1 MUTATED	4	2	2
RREB1 WILD-TYPE	37	9	25

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.25 (Chi-square test), Q value = 1

Table S97. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IDUA MUTATED	9	2	1	2	1
IDUA WILD-TYPE	23	21	14	8	8

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.517 (Chi-square test), Q value = 1

Table S98. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IDUA MUTATED	4	1	4	3	0
IDUA WILD-TYPE	14	10	17	15	11

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S99. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IDUA MUTATED	6	2	2	2
IDUA WILD-TYPE	18	12	15	21

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S100. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IDUA MUTATED	5	4	3
IDUA WILD-TYPE	18	29	19

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S101. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IDUA MUTATED	5	5	2
IDUA WILD-TYPE	32	11	24

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S102. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IDUA MUTATED	4	1	7
IDUA WILD-TYPE	22	9	36

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S103. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IDUA MUTATED	5	5	2
IDUA WILD-TYPE	33	13	21

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S104. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IDUA MUTATED	6	2	4
IDUA WILD-TYPE	35	9	23

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.351 (Chi-square test), Q value = 1

Table S105. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RGS9BP MUTATED	3	3	2	3	0
RGS9BP WILD-TYPE	29	20	13	7	9

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.715 (Chi-square test), Q value = 1

Table S106. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RGS9BP MUTATED	3	1	4	1	1
RGS9BP WILD-TYPE	15	10	17	17	10

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S107. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RGS9BP MUTATED	3	1	2	3
RGS9BP WILD-TYPE	21	13	15	20

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S108. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RGS9BP MUTATED	3	3	3
RGS9BP WILD-TYPE	20	30	19

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S109. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RGS9BP MUTATED	3	3	4
RGS9BP WILD-TYPE	34	13	22

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S110. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RGS9BP MUTATED	3	2	5
RGS9BP WILD-TYPE	23	8	38

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S111. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RGS9BP MUTATED	4	2	4
RGS9BP WILD-TYPE	34	16	19

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S112. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RGS9BP MUTATED	5	2	3
RGS9BP WILD-TYPE	36	9	24

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.753 (Chi-square test), Q value = 1

Table S113. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
WDR34 MUTATED	3	2	2	2	2
WDR34 WILD-TYPE	29	21	13	8	7

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Chi-square test), Q value = 1

Table S114. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
WDR34 MUTATED	2	2	3	1	2
WDR34 WILD-TYPE	16	9	18	17	9

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S115. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
WDR34 MUTATED	4	1	2	3
WDR34 WILD-TYPE	20	13	15	20

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S116. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
WDR34 MUTATED	4	3	3
WDR34 WILD-TYPE	19	30	19

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S117. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
WDR34 MUTATED	6	2	2
WDR34 WILD-TYPE	31	14	24

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S118. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
WDR34 MUTATED	1	2	7
WDR34 WILD-TYPE	25	8	36

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S119. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
WDR34 MUTATED	6	2	2
WDR34 WILD-TYPE	32	16	21

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S120. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
WDR34 MUTATED	7	2	1
WDR34 WILD-TYPE	34	9	26

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S121. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOTCH2 MUTATED	7	1	1	2	1
NOTCH2 WILD-TYPE	25	22	14	8	8

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.573 (Chi-square test), Q value = 1

Table S122. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOTCH2 MUTATED	1	1	3	3	0
NOTCH2 WILD-TYPE	17	10	18	15	11

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S123. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOTCH2 MUTATED	3	1	2	2
NOTCH2 WILD-TYPE	21	13	15	21

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S124. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOTCH2 MUTATED	1	4	3
NOTCH2 WILD-TYPE	22	29	19

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S125. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOTCH2 MUTATED	3	4	1
NOTCH2 WILD-TYPE	34	12	25

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S126. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOTCH2 MUTATED	2	1	5
NOTCH2 WILD-TYPE	24	9	38

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S127. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOTCH2 MUTATED	3	4	1
NOTCH2 WILD-TYPE	35	14	22

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S128. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOTCH2 MUTATED	3	2	3
NOTCH2 WILD-TYPE	38	9	24

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Chi-square test), Q value = 1

Table S129. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TMEM189 MUTATED	6	1	2	3	0
TMEM189 WILD-TYPE	26	22	13	7	9

'TMEM189 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.854 (Chi-square test), Q value = 1

Table S130. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TMEM189 MUTATED	2	2	3	1	1
TMEM189 WILD-TYPE	16	9	18	17	10

'TMEM189 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S131. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TMEM189 MUTATED	4	3	1	1
TMEM189 WILD-TYPE	20	11	16	22

'TMEM189 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0878 (Fisher's exact test), Q value = 1

Table S132. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TMEM189 MUTATED	5	1	3
TMEM189 WILD-TYPE	18	32	19

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S133. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TMEM189 MUTATED	5	3	1
TMEM189 WILD-TYPE	32	13	25

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S134. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TMEM189 MUTATED	3	0	6
TMEM189 WILD-TYPE	23	10	37

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S135. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TMEM189 MUTATED	5	3	1
TMEM189 WILD-TYPE	33	15	22

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S136. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TMEM189 MUTATED	6	0	3
TMEM189 WILD-TYPE	35	11	24

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.408 (Chi-square test), Q value = 1

Table S137. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TAF5 MUTATED	7	2	2	0	1
TAF5 WILD-TYPE	25	21	13	10	8

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.666 (Chi-square test), Q value = 1

Table S138. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TAF5 MUTATED	2	3	2	2	2
TAF5 WILD-TYPE	16	8	19	16	9

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S139. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TAF5 MUTATED	4	2	2	3
TAF5 WILD-TYPE	20	12	15	20

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S140. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TAF5 MUTATED	5	4	2
TAF5 WILD-TYPE	18	29	20

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S141. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TAF5 MUTATED	4	4	3
TAF5 WILD-TYPE	33	12	23

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0703 (Fisher's exact test), Q value = 1

Table S142. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TAF5 MUTATED	7	0	4
TAF5 WILD-TYPE	19	10	39

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S143. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TAF5 MUTATED	4	5	2
TAF5 WILD-TYPE	34	13	21

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S144. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TAF5 MUTATED	3	1	7
TAF5 WILD-TYPE	38	10	20

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00701 (Chi-square test), Q value = 1

Table S145. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRP11 MUTATED	1	2	1	4	0
LRP11 WILD-TYPE	31	21	14	6	9

Figure S2. Get High-res Image Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.373 (Chi-square test), Q value = 1

Table S146. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRP11 MUTATED	1	0	4	1	1
LRP11 WILD-TYPE	17	11	17	17	10

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S147. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRP11 MUTATED	2	1	2	2
LRP11 WILD-TYPE	22	13	15	21

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S148. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRP11 MUTATED	2	2	3
LRP11 WILD-TYPE	21	31	19

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S149. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRP11 MUTATED	4	2	1
LRP11 WILD-TYPE	33	14	25

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S150. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRP11 MUTATED	2	0	5
LRP11 WILD-TYPE	24	10	38

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S151. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRP11 MUTATED	4	2	1
LRP11 WILD-TYPE	34	16	22

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S152. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRP11 MUTATED	4	1	2
LRP11 WILD-TYPE	37	10	25

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Chi-square test), Q value = 1

Table S153. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FPGS MUTATED	2	4	4	3	1
FPGS WILD-TYPE	30	19	11	7	8

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.515 (Chi-square test), Q value = 1

Table S154. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FPGS MUTATED	1	1	5	2	2
FPGS WILD-TYPE	17	10	16	16	9

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0636 (Fisher's exact test), Q value = 1

Table S155. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FPGS MUTATED	2	4	0	5
FPGS WILD-TYPE	22	10	17	18

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S156. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FPGS MUTATED	3	5	3
FPGS WILD-TYPE	20	28	19

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S157. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FPGS MUTATED	4	2	5
FPGS WILD-TYPE	33	14	21

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S158. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FPGS MUTATED	4	1	6
FPGS WILD-TYPE	22	9	37

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S159. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FPGS MUTATED	5	1	5
FPGS WILD-TYPE	33	17	18

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S160. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FPGS MUTATED	6	1	4
FPGS WILD-TYPE	35	10	23

'BAG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.956 (Chi-square test), Q value = 1

Table S161. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BAG1 MUTATED	2	1	1	1	1
BAG1 WILD-TYPE	30	22	14	9	8

'BAG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S162. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BAG1 MUTATED	1	0	3	0	1
BAG1 WILD-TYPE	17	11	18	18	10

'BAG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S163. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BAG1 MUTATED	1	0	2	2
BAG1 WILD-TYPE	23	14	15	21

'BAG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S164. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BAG1 MUTATED	1	3	1
BAG1 WILD-TYPE	22	30	21

'BAG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S165. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BAG1 MUTATED	1	1	3
BAG1 WILD-TYPE	36	15	23

'BAG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0804 (Fisher's exact test), Q value = 1

Table S166. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BAG1 MUTATED	2	2	1
BAG1 WILD-TYPE	24	8	42

'BAG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S167. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BAG1 MUTATED	1	1	3
BAG1 WILD-TYPE	37	17	20

'BAG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S168. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BAG1 MUTATED	1	2	2
BAG1 WILD-TYPE	40	9	25

'FZD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.424 (Chi-square test), Q value = 1

Table S169. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FZD1 MUTATED	3	0	2	1	0
FZD1 WILD-TYPE	29	23	13	9	9

'FZD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S170. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FZD1 MUTATED	0	1	2	0	0
FZD1 WILD-TYPE	18	10	19	18	11

'FZD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S171. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FZD1 MUTATED	1	1	1	0
FZD1 WILD-TYPE	23	13	16	23

'FZD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S172. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FZD1 MUTATED	1	0	2
FZD1 WILD-TYPE	22	33	20

'FZD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S173. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	34	16	26

'FZD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S174. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FZD1 MUTATED	0	0	3
FZD1 WILD-TYPE	26	10	40

'FZD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S175. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	35	18	23

'FZD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S176. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	38	11	27

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.674 (Chi-square test), Q value = 1

Table S177. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TOR3A MUTATED	10	4	4	4	2
TOR3A WILD-TYPE	22	19	11	6	7

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0628 (Chi-square test), Q value = 1

Table S178. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TOR3A MUTATED	3	0	8	8	3
TOR3A WILD-TYPE	15	11	13	10	8

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S179. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TOR3A MUTATED	4	4	6	8
TOR3A WILD-TYPE	20	10	11	15

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0295 (Fisher's exact test), Q value = 1

Table S180. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TOR3A MUTATED	2	13	7
TOR3A WILD-TYPE	21	20	15

Figure S3. Get High-res Image Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S181. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TOR3A MUTATED	10	4	8
TOR3A WILD-TYPE	27	12	18

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S182. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TOR3A MUTATED	10	1	11
TOR3A WILD-TYPE	16	9	32

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S183. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TOR3A MUTATED	10	5	7
TOR3A WILD-TYPE	28	13	16

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S184. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TOR3A MUTATED	10	2	10
TOR3A WILD-TYPE	31	9	17

'TMEM200C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.652 (Chi-square test), Q value = 1

Table S185. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TMEM200C MUTATED	3	0	1	1	1
TMEM200C WILD-TYPE	29	23	14	9	8

'TMEM200C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S186. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TMEM200C MUTATED	0	0	2	0	1
TMEM200C WILD-TYPE	18	11	19	18	10

'TMEM200C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0137 (Fisher's exact test), Q value = 1

Table S187. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TMEM200C MUTATED	0	0	3	0
TMEM200C WILD-TYPE	24	14	14	23

Figure S4. Get High-res Image Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TMEM200C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S188. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TMEM200C MUTATED	0	1	2
TMEM200C WILD-TYPE	23	32	20

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S189. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TMEM200C MUTATED	2	0	1
TMEM200C WILD-TYPE	35	16	25

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S190. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TMEM200C MUTATED	1	0	2
TMEM200C WILD-TYPE	25	10	41

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S191. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TMEM200C MUTATED	2	1	0
TMEM200C WILD-TYPE	36	17	23

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S192. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TMEM200C MUTATED	2	0	1
TMEM200C WILD-TYPE	39	11	26

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.59 (Chi-square test), Q value = 1

Table S193. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF517 MUTATED	14	9	6	2	2
ZNF517 WILD-TYPE	18	14	9	8	7

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Chi-square test), Q value = 1

Table S194. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF517 MUTATED	7	3	7	6	3
ZNF517 WILD-TYPE	11	8	14	12	8

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S195. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF517 MUTATED	9	6	5	6
ZNF517 WILD-TYPE	15	8	12	17

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S196. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF517 MUTATED	8	10	8
ZNF517 WILD-TYPE	15	23	14

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S197. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF517 MUTATED	12	7	7
ZNF517 WILD-TYPE	25	9	19

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S198. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF517 MUTATED	9	3	14
ZNF517 WILD-TYPE	17	7	29

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S199. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF517 MUTATED	13	7	6
ZNF517 WILD-TYPE	25	11	17

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S200. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF517 MUTATED	13	4	9
ZNF517 WILD-TYPE	28	7	18

'DMRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.635 (Chi-square test), Q value = 1

Table S201. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMRT1 MUTATED	1	2	0	1	1
DMRT1 WILD-TYPE	31	21	15	9	8

'DMRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.24 (Chi-square test), Q value = 1

Table S202. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMRT1 MUTATED	0	0	1	1	2
DMRT1 WILD-TYPE	18	11	20	17	9

'DMRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S203. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMRT1 MUTATED	0	0	2	2
DMRT1 WILD-TYPE	24	14	15	21

'DMRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0922 (Fisher's exact test), Q value = 1

Table S204. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMRT1 MUTATED	0	4	0
DMRT1 WILD-TYPE	23	29	22

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0209 (Fisher's exact test), Q value = 1

Table S205. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMRT1 MUTATED	0	0	4
DMRT1 WILD-TYPE	37	16	22

Figure S5. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00222 (Fisher's exact test), Q value = 1

Table S206. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMRT1 MUTATED	1	3	0
DMRT1 WILD-TYPE	25	7	43

Figure S6. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0623 (Fisher's exact test), Q value = 1

Table S207. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMRT1 MUTATED	0	1	3
DMRT1 WILD-TYPE	38	17	20

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00318 (Fisher's exact test), Q value = 1

Table S208. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMRT1 MUTATED	0	3	1
DMRT1 WILD-TYPE	41	8	26

Figure S7. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.339 (Chi-square test), Q value = 1

Table S209. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLTPD2 MUTATED	7	2	4	4	2
GLTPD2 WILD-TYPE	25	21	11	6	7

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Chi-square test), Q value = 1

Table S210. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLTPD2 MUTATED	3	2	5	4	3
GLTPD2 WILD-TYPE	15	9	16	14	8

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.955 (Fisher's exact test), Q value = 1

Table S211. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLTPD2 MUTATED	6	3	3	5
GLTPD2 WILD-TYPE	18	11	14	18

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S212. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLTPD2 MUTATED	5	6	6
GLTPD2 WILD-TYPE	18	27	16

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S213. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLTPD2 MUTATED	8	5	4
GLTPD2 WILD-TYPE	29	11	22

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S214. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLTPD2 MUTATED	4	3	10
GLTPD2 WILD-TYPE	22	7	33

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S215. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLTPD2 MUTATED	8	5	4
GLTPD2 WILD-TYPE	30	13	19

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S216. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLTPD2 MUTATED	9	3	5
GLTPD2 WILD-TYPE	32	8	22

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Chi-square test), Q value = 1

Table S217. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SEMA5B MUTATED	10	2	2	1	1
SEMA5B WILD-TYPE	22	21	13	9	8

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.637 (Chi-square test), Q value = 1

Table S218. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SEMA5B MUTATED	4	1	2	4	1
SEMA5B WILD-TYPE	14	10	19	14	10

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S219. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SEMA5B MUTATED	6	3	0	3
SEMA5B WILD-TYPE	18	11	17	20

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S220. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SEMA5B MUTATED	6	4	2
SEMA5B WILD-TYPE	17	29	20

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S221. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SEMA5B MUTATED	6	3	3
SEMA5B WILD-TYPE	31	13	23

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S222. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SEMA5B MUTATED	5	1	6
SEMA5B WILD-TYPE	21	9	37

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S223. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SEMA5B MUTATED	6	3	3
SEMA5B WILD-TYPE	32	15	20

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S224. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SEMA5B MUTATED	6	1	5
SEMA5B WILD-TYPE	35	10	22

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.589 (Chi-square test), Q value = 1

Table S225. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TNIP2 MUTATED	4	1	0	1	1
TNIP2 WILD-TYPE	28	22	15	9	8

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.293 (Chi-square test), Q value = 1

Table S226. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TNIP2 MUTATED	1	2	2	0	0
TNIP2 WILD-TYPE	17	9	19	18	11

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S227. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TNIP2 MUTATED	2	0	2	1
TNIP2 WILD-TYPE	22	14	15	22

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S228. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TNIP2 MUTATED	2	1	2
TNIP2 WILD-TYPE	21	32	20

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S229. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TNIP2 MUTATED	3	1	1
TNIP2 WILD-TYPE	34	15	25

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S230. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TNIP2 MUTATED	0	1	4
TNIP2 WILD-TYPE	26	9	39

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TNIP2 MUTATED	3	1	1
TNIP2 WILD-TYPE	35	17	22

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S232. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TNIP2 MUTATED	4	1	0
TNIP2 WILD-TYPE	37	10	27

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.134 (Chi-square test), Q value = 1

Table S233. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HHIPL1 MUTATED	6	1	4	3	0
HHIPL1 WILD-TYPE	26	22	11	7	9

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.961 (Chi-square test), Q value = 1

Table S234. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HHIPL1 MUTATED	2	1	3	3	2
HHIPL1 WILD-TYPE	16	10	18	15	9

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S235. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HHIPL1 MUTATED	5	3	2	1
HHIPL1 WILD-TYPE	19	11	15	22

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S236. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HHIPL1 MUTATED	3	4	4
HHIPL1 WILD-TYPE	20	29	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0149 (Fisher's exact test), Q value = 1

Table S237. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HHIPL1 MUTATED	9	2	0
HHIPL1 WILD-TYPE	28	14	26

Figure S8. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0376 (Fisher's exact test), Q value = 1

Table S238. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HHIPL1 MUTATED	1	0	10
HHIPL1 WILD-TYPE	25	10	33

Figure S9. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S239. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HHIPL1 MUTATED	9	2	0
HHIPL1 WILD-TYPE	29	16	23

Figure S10. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S240. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HHIPL1 MUTATED	9	0	2
HHIPL1 WILD-TYPE	32	11	25

'HECTD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.746 (Chi-square test), Q value = 1

Table S241. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HECTD2 MUTATED	3	1	2	1	0
HECTD2 WILD-TYPE	29	22	13	9	9

'HECTD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Chi-square test), Q value = 1

Table S242. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HECTD2 MUTATED	3	0	2	1	0
HECTD2 WILD-TYPE	15	11	19	17	11

'HECTD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S243. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HECTD2 MUTATED	3	2	0	1
HECTD2 WILD-TYPE	21	12	17	22

'HECTD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S244. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HECTD2 MUTATED	3	1	2
HECTD2 WILD-TYPE	20	32	20

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S245. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HECTD2 MUTATED	3	2	1
HECTD2 WILD-TYPE	34	14	25

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S246. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HECTD2 MUTATED	2	1	3
HECTD2 WILD-TYPE	24	9	40

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S247. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HECTD2 MUTATED	3	2	1
HECTD2 WILD-TYPE	35	16	22

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S248. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HECTD2 MUTATED	3	1	2
HECTD2 WILD-TYPE	38	10	25

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Chi-square test), Q value = 1

Table S249. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ADAD2 MUTATED	5	1	5	3	1
ADAD2 WILD-TYPE	27	22	10	7	8

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.141 (Chi-square test), Q value = 1

Table S250. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ADAD2 MUTATED	1	0	6	3	3
ADAD2 WILD-TYPE	17	11	15	15	8

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S251. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ADAD2 MUTATED	3	3	3	4
ADAD2 WILD-TYPE	21	11	14	19

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S252. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ADAD2 MUTATED	2	5	6
ADAD2 WILD-TYPE	21	28	16

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S253. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ADAD2 MUTATED	5	4	4
ADAD2 WILD-TYPE	32	12	22

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S254. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ADAD2 MUTATED	6	1	6
ADAD2 WILD-TYPE	20	9	37

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S255. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ADAD2 MUTATED	5	4	4
ADAD2 WILD-TYPE	33	14	19

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S256. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ADAD2 MUTATED	6	1	6
ADAD2 WILD-TYPE	35	10	21

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.435 (Chi-square test), Q value = 1

Table S257. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CTNNB1 MUTATED	7	2	3	2	0
CTNNB1 WILD-TYPE	25	21	12	8	9

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0574 (Chi-square test), Q value = 1

Table S258. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CTNNB1 MUTATED	5	4	2	0	2
CTNNB1 WILD-TYPE	13	7	19	18	9

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.000193 (Fisher's exact test), Q value = 0.22

Table S259. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CTNNB1 MUTATED	8	5	0	0
CTNNB1 WILD-TYPE	16	9	17	23

Figure S11. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3.12e-05 (Fisher's exact test), Q value = 0.036

Table S260. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CTNNB1 MUTATED	10	0	3
CTNNB1 WILD-TYPE	13	33	19

Figure S12. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.000643 (Fisher's exact test), Q value = 0.74

Table S261. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CTNNB1 MUTATED	6	7	0
CTNNB1 WILD-TYPE	31	9	26

Figure S13. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S262. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CTNNB1 MUTATED	4	0	9
CTNNB1 WILD-TYPE	22	10	34

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00645 (Fisher's exact test), Q value = 1

Table S263. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CTNNB1 MUTATED	7	6	0
CTNNB1 WILD-TYPE	31	12	23

Figure S14. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S264. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CTNNB1 MUTATED	9	0	4
CTNNB1 WILD-TYPE	32	11	23

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.225 (Chi-square test), Q value = 1

Table S265. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZFPM1 MUTATED	19	10	8	8	3
ZFPM1 WILD-TYPE	13	13	7	2	6

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Chi-square test), Q value = 1

Table S266. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZFPM1 MUTATED	10	6	9	10	5
ZFPM1 WILD-TYPE	8	5	12	8	6

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S267. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZFPM1 MUTATED	13	6	9	12
ZFPM1 WILD-TYPE	11	8	8	11

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S268. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZFPM1 MUTATED	13	16	11
ZFPM1 WILD-TYPE	10	17	11

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S269. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZFPM1 MUTATED	19	9	12
ZFPM1 WILD-TYPE	18	7	14

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S270. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZFPM1 MUTATED	16	3	21
ZFPM1 WILD-TYPE	10	7	22

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S271. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZFPM1 MUTATED	19	11	10
ZFPM1 WILD-TYPE	19	7	13

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S272. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZFPM1 MUTATED	20	4	16
ZFPM1 WILD-TYPE	21	7	11

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.207 (Chi-square test), Q value = 1

Table S273. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CLDN23 MUTATED	3	5	2	0	3
CLDN23 WILD-TYPE	29	18	13	10	6

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.361 (Chi-square test), Q value = 1

Table S274. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CLDN23 MUTATED	1	3	2	3	3
CLDN23 WILD-TYPE	17	8	19	15	8

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S275. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CLDN23 MUTATED	1	2	1	8
CLDN23 WILD-TYPE	23	12	16	15

Figure S15. Get High-res Image Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S276. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CLDN23 MUTATED	3	8	1
CLDN23 WILD-TYPE	20	25	21

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 1

Table S277. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CLDN23 MUTATED	3	2	7
CLDN23 WILD-TYPE	34	14	19

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S278. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CLDN23 MUTATED	4	3	5
CLDN23 WILD-TYPE	22	7	38

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 1

Table S279. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CLDN23 MUTATED	3	3	6
CLDN23 WILD-TYPE	35	15	17

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S280. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CLDN23 MUTATED	5	3	4
CLDN23 WILD-TYPE	36	8	23

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0641 (Chi-square test), Q value = 1

Table S281. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC105 MUTATED	3	2	2	4	0
CCDC105 WILD-TYPE	29	21	13	6	9

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00159 (Chi-square test), Q value = 1

Table S282. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC105 MUTATED	1	5	1	0	3
CCDC105 WILD-TYPE	17	6	20	18	8

Figure S16. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S283. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC105 MUTATED	4	2	2	2
CCDC105 WILD-TYPE	20	12	15	21

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S284. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC105 MUTATED	6	2	2
CCDC105 WILD-TYPE	17	31	20

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S285. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC105 MUTATED	7	1	2
CCDC105 WILD-TYPE	30	15	24

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S286. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC105 MUTATED	0	1	9
CCDC105 WILD-TYPE	26	9	34

Figure S17. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S287. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC105 MUTATED	7	2	1
CCDC105 WILD-TYPE	31	16	22

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0166 (Fisher's exact test), Q value = 1

Table S288. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC105 MUTATED	9	1	0
CCDC105 WILD-TYPE	32	10	27

Figure S18. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.688 (Chi-square test), Q value = 1

Table S289. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMKN MUTATED	1	1	0	1	0
DMKN WILD-TYPE	31	22	15	9	9

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S290. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMKN MUTATED	0	1	2	0	0
DMKN WILD-TYPE	18	10	19	18	11

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S291. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	23	13	16	23

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S292. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMKN MUTATED	1	0	2
DMKN WILD-TYPE	22	33	20

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00708 (Fisher's exact test), Q value = 1

Table S293. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	37	13	26

Figure S19. Get High-res Image Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S294. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMKN MUTATED	1	0	2
DMKN WILD-TYPE	25	10	41

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0103 (Fisher's exact test), Q value = 1

Table S295. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	38	15	23

Figure S20. Get High-res Image Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S296. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMKN MUTATED	2	0	1
DMKN WILD-TYPE	39	11	26

'NOL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.469 (Chi-square test), Q value = 1

Table S297. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOL9 MUTATED	5	2	1	3	1
NOL9 WILD-TYPE	27	21	14	7	8

'NOL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.647 (Chi-square test), Q value = 1

Table S298. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOL9 MUTATED	3	2	2	2	0
NOL9 WILD-TYPE	15	9	19	16	11

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S299. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOL9 MUTATED	5	0	2	2
NOL9 WILD-TYPE	19	14	15	21

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S300. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	18	31	20

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S301. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	32	14	24

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S302. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOL9 MUTATED	3	0	6
NOL9 WILD-TYPE	23	10	37

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S303. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	33	16	21

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S304. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOL9 MUTATED	6	0	3
NOL9 WILD-TYPE	35	11	24

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Chi-square test), Q value = 1

Table S305. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C19ORF10 MUTATED	4	2	1	2	0
C19ORF10 WILD-TYPE	28	21	14	8	9

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.16 (Chi-square test), Q value = 1

Table S306. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C19ORF10 MUTATED	4	1	3	0	0
C19ORF10 WILD-TYPE	14	10	18	18	11

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S307. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C19ORF10 MUTATED	3	3	2	0
C19ORF10 WILD-TYPE	21	11	15	23

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00708 (Fisher's exact test), Q value = 1

Table S308. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C19ORF10 MUTATED	3	0	5
C19ORF10 WILD-TYPE	20	33	17

Figure S21. Get High-res Image Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 1

Table S309. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C19ORF10 MUTATED	4	3	1
C19ORF10 WILD-TYPE	33	13	25

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S310. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C19ORF10 MUTATED	3	0	5
C19ORF10 WILD-TYPE	23	10	38

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S311. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C19ORF10 MUTATED	5	3	0
C19ORF10 WILD-TYPE	33	15	23

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S312. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C19ORF10 MUTATED	5	0	3
C19ORF10 WILD-TYPE	36	11	24

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Chi-square test), Q value = 1

Table S313. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF598 MUTATED	8	3	2	4	2
ZNF598 WILD-TYPE	24	20	13	6	7

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.414 (Chi-square test), Q value = 1

Table S314. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF598 MUTATED	3	0	3	5	2
ZNF598 WILD-TYPE	15	11	18	13	9

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S315. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF598 MUTATED	5	1	3	4
ZNF598 WILD-TYPE	19	13	14	19

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S316. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF598 MUTATED	4	6	3
ZNF598 WILD-TYPE	19	27	19

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S317. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF598 MUTATED	5	3	5
ZNF598 WILD-TYPE	32	13	21

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S318. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF598 MUTATED	5	1	7
ZNF598 WILD-TYPE	21	9	36

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S319. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF598 MUTATED	5	3	5
ZNF598 WILD-TYPE	33	15	18

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S320. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF598 MUTATED	6	1	6
ZNF598 WILD-TYPE	35	10	21

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00763 (Chi-square test), Q value = 1

Table S321. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
THEM4 MUTATED	4	0	3	5	2
THEM4 WILD-TYPE	28	23	12	5	7

Figure S22. Get High-res Image Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.251 (Chi-square test), Q value = 1

Table S322. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
THEM4 MUTATED	1	3	3	1	3
THEM4 WILD-TYPE	17	8	18	17	8

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.97 (Fisher's exact test), Q value = 1

Table S323. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
THEM4 MUTATED	3	2	3	3
THEM4 WILD-TYPE	21	12	14	20

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S324. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
THEM4 MUTATED	4	4	3
THEM4 WILD-TYPE	19	29	19

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S325. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
THEM4 MUTATED	6	3	2
THEM4 WILD-TYPE	31	13	24

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S326. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
THEM4 MUTATED	1	2	8
THEM4 WILD-TYPE	25	8	35

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S327. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
THEM4 MUTATED	6	3	2
THEM4 WILD-TYPE	32	15	21

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0872 (Fisher's exact test), Q value = 1

Table S328. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
THEM4 MUTATED	7	3	1
THEM4 WILD-TYPE	34	8	26

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.533 (Chi-square test), Q value = 1

Table S329. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRIG1 MUTATED	12	5	7	4	4
LRIG1 WILD-TYPE	20	18	8	6	5

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.731 (Chi-square test), Q value = 1

Table S330. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRIG1 MUTATED	6	5	8	6	2
LRIG1 WILD-TYPE	12	6	13	12	9

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S331. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRIG1 MUTATED	9	6	4	7
LRIG1 WILD-TYPE	15	8	13	16

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S332. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRIG1 MUTATED	9	11	6
LRIG1 WILD-TYPE	14	22	16

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S333. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRIG1 MUTATED	12	8	7
LRIG1 WILD-TYPE	25	8	19

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S334. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRIG1 MUTATED	8	4	15
LRIG1 WILD-TYPE	18	6	28

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S335. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRIG1 MUTATED	13	7	7
LRIG1 WILD-TYPE	25	11	16

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S336. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRIG1 MUTATED	14	5	8
LRIG1 WILD-TYPE	27	6	19

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.759 (Chi-square test), Q value = 1

Table S337. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MUC5B MUTATED	7	6	4	3	4
MUC5B WILD-TYPE	25	17	11	7	5

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.248 (Chi-square test), Q value = 1

Table S338. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MUC5B MUTATED	3	3	7	4	6
MUC5B WILD-TYPE	15	8	14	14	5

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S339. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MUC5B MUTATED	5	4	8	6
MUC5B WILD-TYPE	19	10	9	17

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S340. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MUC5B MUTATED	4	11	8
MUC5B WILD-TYPE	19	22	14

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S341. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MUC5B MUTATED	9	5	9
MUC5B WILD-TYPE	28	11	17

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S342. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MUC5B MUTATED	8	3	12
MUC5B WILD-TYPE	18	7	31

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S343. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MUC5B MUTATED	9	7	7
MUC5B WILD-TYPE	29	11	16

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S344. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MUC5B MUTATED	11	3	9
MUC5B WILD-TYPE	30	8	18

'CTGF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.632 (Chi-square test), Q value = 1

Table S345. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CTGF MUTATED	3	2	0	0	1
CTGF WILD-TYPE	29	21	15	10	8

'CTGF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.397 (Chi-square test), Q value = 1

Table S346. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CTGF MUTATED	0	1	1	1	2
CTGF WILD-TYPE	18	10	20	17	9

'CTGF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S347. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CTGF MUTATED	2	1	0	2
CTGF WILD-TYPE	22	13	17	21

'CTGF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S348. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CTGF MUTATED	1	3	1
CTGF WILD-TYPE	22	30	21

'CTGF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S349. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	36	14	24

'CTGF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S350. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	25	8	41

'CTGF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S351. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	37	16	21

'CTGF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S352. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	40	9	25

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0677 (Chi-square test), Q value = 1

Table S353. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AMDHD1 MUTATED	8	2	2	5	1
AMDHD1 WILD-TYPE	24	21	13	5	8

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.896 (Chi-square test), Q value = 1

Table S354. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AMDHD1 MUTATED	2	2	5	3	2
AMDHD1 WILD-TYPE	16	9	16	15	9

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S355. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AMDHD1 MUTATED	5	3	4	2
AMDHD1 WILD-TYPE	19	11	13	21

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S356. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AMDHD1 MUTATED	3	6	5
AMDHD1 WILD-TYPE	20	27	17

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 1

Table S357. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AMDHD1 MUTATED	6	5	3
AMDHD1 WILD-TYPE	31	11	23

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S358. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AMDHD1 MUTATED	6	0	8
AMDHD1 WILD-TYPE	20	10	35

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0186 (Fisher's exact test), Q value = 1

Table S359. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AMDHD1 MUTATED	6	7	1
AMDHD1 WILD-TYPE	32	11	22

Figure S23. Get High-res Image Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S360. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AMDHD1 MUTATED	6	1	7
AMDHD1 WILD-TYPE	35	10	20

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Chi-square test), Q value = 1

Table S361. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF149 MUTATED	2	3	1	1	0
RNF149 WILD-TYPE	30	20	14	9	9

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.56 (Chi-square test), Q value = 1

Table S362. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF149 MUTATED	1	0	2	1	2
RNF149 WILD-TYPE	17	11	19	17	9

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S363. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF149 MUTATED	1	1	2	2
RNF149 WILD-TYPE	23	13	15	21

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S364. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	22	30	20

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0871 (Fisher's exact test), Q value = 1

Table S365. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	36	13	24

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S366. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF149 MUTATED	4	1	1
RNF149 WILD-TYPE	22	9	42

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S367. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	37	15	21

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S368. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF149 MUTATED	1	1	4
RNF149 WILD-TYPE	40	10	23

'MSH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00899 (Chi-square test), Q value = 1

Table S369. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MSH3 MUTATED	1	0	1	3	0
MSH3 WILD-TYPE	31	23	14	7	9

Figure S24. Get High-res Image Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'MSH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S370. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MSH3 MUTATED	1	0	2	0	1
MSH3 WILD-TYPE	17	11	19	18	10

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0701 (Fisher's exact test), Q value = 1

Table S371. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MSH3 MUTATED	1	0	3	0
MSH3 WILD-TYPE	23	14	14	23

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S372. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MSH3 MUTATED	1	1	2
MSH3 WILD-TYPE	22	32	20

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S373. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	33	16	26

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S374. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MSH3 MUTATED	0	0	4
MSH3 WILD-TYPE	26	10	39

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S375. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	34	18	23

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S376. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	37	11	27

'ALPPL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.907 (Chi-square test), Q value = 1

Table S377. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ALPPL2 MUTATED	3	1	2	1	1
ALPPL2 WILD-TYPE	29	22	13	9	8

'ALPPL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.121 (Chi-square test), Q value = 1

Table S378. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ALPPL2 MUTATED	4	0	0	2	2
ALPPL2 WILD-TYPE	14	11	21	16	9

'ALPPL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S379. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ALPPL2 MUTATED	4	1	0	3
ALPPL2 WILD-TYPE	20	13	17	20

'ALPPL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S380. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ALPPL2 MUTATED	4	3	1
ALPPL2 WILD-TYPE	19	30	21

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S381. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ALPPL2 MUTATED	5	1	2
ALPPL2 WILD-TYPE	32	15	24

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S382. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ALPPL2 MUTATED	1	2	5
ALPPL2 WILD-TYPE	25	8	38

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S383. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ALPPL2 MUTATED	5	1	2
ALPPL2 WILD-TYPE	33	17	21

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S384. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ALPPL2 MUTATED	5	2	1
ALPPL2 WILD-TYPE	36	9	26

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Chi-square test), Q value = 1

Table S385. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SNED1 MUTATED	4	1	1	0	1
SNED1 WILD-TYPE	28	22	14	10	8

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.623 (Chi-square test), Q value = 1

Table S386. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SNED1 MUTATED	2	2	2	1	0
SNED1 WILD-TYPE	16	9	19	17	11

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S387. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SNED1 MUTATED	4	1	1	1
SNED1 WILD-TYPE	20	13	16	22

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S388. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SNED1 MUTATED	3	2	2
SNED1 WILD-TYPE	20	31	20

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0417 (Fisher's exact test), Q value = 1

Table S389. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SNED1 MUTATED	2	4	1
SNED1 WILD-TYPE	35	12	25

Figure S25. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S390. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SNED1 MUTATED	3	1	3
SNED1 WILD-TYPE	23	9	40

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S391. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SNED1 MUTATED	2	4	1
SNED1 WILD-TYPE	36	14	22

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S392. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SNED1 MUTATED	3	1	3
SNED1 WILD-TYPE	38	10	24

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.284 (Chi-square test), Q value = 1

Table S393. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOXA1 MUTATED	3	0	2	0	0
NOXA1 WILD-TYPE	29	23	13	10	9

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.371 (Chi-square test), Q value = 1

Table S394. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOXA1 MUTATED	2	0	1	0	0
NOXA1 WILD-TYPE	16	11	20	18	11

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 1

Table S395. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	22	13	17	23

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S396. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOXA1 MUTATED	2	0	1
NOXA1 WILD-TYPE	21	33	21

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S397. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	34	16	26

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S398. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOXA1 MUTATED	0	0	3
NOXA1 WILD-TYPE	26	10	40

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S399. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	35	18	23

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S400. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	38	11	27

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.24 (Chi-square test), Q value = 1

Table S401. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
OPRD1 MUTATED	12	6	4	4	0
OPRD1 WILD-TYPE	20	17	11	6	9

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.832 (Chi-square test), Q value = 1

Table S402. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
OPRD1 MUTATED	6	2	6	4	4
OPRD1 WILD-TYPE	12	9	15	14	7

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S403. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
OPRD1 MUTATED	8	5	3	6
OPRD1 WILD-TYPE	16	9	14	17

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S404. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
OPRD1 MUTATED	7	8	7
OPRD1 WILD-TYPE	16	25	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S405. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
OPRD1 MUTATED	12	5	5
OPRD1 WILD-TYPE	25	11	21

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S406. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
OPRD1 MUTATED	8	1	13
OPRD1 WILD-TYPE	18	9	30

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S407. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
OPRD1 MUTATED	12	5	5
OPRD1 WILD-TYPE	26	13	18

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S408. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
OPRD1 MUTATED	11	2	9
OPRD1 WILD-TYPE	30	9	18

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.587 (Chi-square test), Q value = 1

Table S409. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC102A MUTATED	9	8	2	4	3
CCDC102A WILD-TYPE	23	15	13	6	6

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S410. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC102A MUTATED	4	3	8	5	3
CCDC102A WILD-TYPE	14	8	13	13	8

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S411. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC102A MUTATED	6	5	5	7
CCDC102A WILD-TYPE	18	9	12	16

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S412. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC102A MUTATED	6	11	6
CCDC102A WILD-TYPE	17	22	16

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S413. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC102A MUTATED	11	3	9
CCDC102A WILD-TYPE	26	13	17

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S414. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC102A MUTATED	8	4	11
CCDC102A WILD-TYPE	18	6	32

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S415. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC102A MUTATED	11	4	8
CCDC102A WILD-TYPE	27	14	15

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S416. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC102A MUTATED	10	5	8
CCDC102A WILD-TYPE	31	6	19

'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Chi-square test), Q value = 1

Table S417. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KCTD3 MUTATED	2	1	2	3	0
KCTD3 WILD-TYPE	30	22	13	7	9

'KCTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0699 (Chi-square test), Q value = 1

Table S418. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KCTD3 MUTATED	0	0	2	1	3
KCTD3 WILD-TYPE	18	11	19	17	8

'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S419. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KCTD3 MUTATED	1	2	1	2
KCTD3 WILD-TYPE	23	12	16	21

'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S420. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KCTD3 MUTATED	1	2	3
KCTD3 WILD-TYPE	22	31	19

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S421. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KCTD3 MUTATED	3	1	2
KCTD3 WILD-TYPE	34	15	24

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S422. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KCTD3 MUTATED	1	1	4
KCTD3 WILD-TYPE	25	9	39

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S423. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KCTD3 MUTATED	3	1	2
KCTD3 WILD-TYPE	35	17	21

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S424. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KCTD3 MUTATED	4	1	1
KCTD3 WILD-TYPE	37	10	26

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.9 (Chi-square test), Q value = 1

Table S425. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C1ORF106 MUTATED	7	3	3	2	1
C1ORF106 WILD-TYPE	25	20	12	8	8

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.439 (Chi-square test), Q value = 1

Table S426. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C1ORF106 MUTATED	3	1	4	2	4
C1ORF106 WILD-TYPE	15	10	17	16	7

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S427. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C1ORF106 MUTATED	6	3	3	2
C1ORF106 WILD-TYPE	18	11	14	21

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S428. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C1ORF106 MUTATED	5	6	3
C1ORF106 WILD-TYPE	18	27	19

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S429. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C1ORF106 MUTATED	7	3	4
C1ORF106 WILD-TYPE	30	13	22

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S430. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C1ORF106 MUTATED	4	3	7
C1ORF106 WILD-TYPE	22	7	36

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S431. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C1ORF106 MUTATED	7	4	3
C1ORF106 WILD-TYPE	31	14	20

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S432. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C1ORF106 MUTATED	7	3	4
C1ORF106 WILD-TYPE	34	8	23

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.135 (Chi-square test), Q value = 1

Table S433. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KCNK17 MUTATED	4	3	5	3	4
KCNK17 WILD-TYPE	28	20	10	7	5

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0959 (Chi-square test), Q value = 1

Table S434. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KCNK17 MUTATED	3	3	9	2	1
KCNK17 WILD-TYPE	15	8	12	16	10

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S435. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KCNK17 MUTATED	3	5	6	4
KCNK17 WILD-TYPE	21	9	11	19

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0117 (Fisher's exact test), Q value = 1

Table S436. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KCNK17 MUTATED	2	6	10
KCNK17 WILD-TYPE	21	27	12

Figure S26. Get High-res Image Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S437. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KCNK17 MUTATED	8	4	6
KCNK17 WILD-TYPE	29	12	20

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S438. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KCNK17 MUTATED	4	4	10
KCNK17 WILD-TYPE	22	6	33

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S439. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KCNK17 MUTATED	8	5	5
KCNK17 WILD-TYPE	30	13	18

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S440. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KCNK17 MUTATED	9	4	5
KCNK17 WILD-TYPE	32	7	22

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0645 (Chi-square test), Q value = 1

Table S441. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LACTB MUTATED	8	6	3	7	3
LACTB WILD-TYPE	24	17	12	3	6

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Chi-square test), Q value = 1

Table S442. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LACTB MUTATED	3	5	5	5	5
LACTB WILD-TYPE	15	6	16	13	6

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S443. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LACTB MUTATED	8	3	5	7
LACTB WILD-TYPE	16	11	12	16

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S444. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LACTB MUTATED	7	10	6
LACTB WILD-TYPE	16	23	16

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S445. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LACTB MUTATED	9	6	8
LACTB WILD-TYPE	28	10	18

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S446. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LACTB MUTATED	7	4	12
LACTB WILD-TYPE	19	6	31

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S447. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LACTB MUTATED	9	7	7
LACTB WILD-TYPE	29	11	16

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S448. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LACTB MUTATED	11	4	8
LACTB WILD-TYPE	30	7	19

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.713 (Chi-square test), Q value = 1

Table S449. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TRIOBP MUTATED	10	5	5	3	1
TRIOBP WILD-TYPE	22	18	10	7	8

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S450. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TRIOBP MUTATED	6	2	4	4	4
TRIOBP WILD-TYPE	12	9	17	14	7

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S451. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TRIOBP MUTATED	7	4	4	4
TRIOBP WILD-TYPE	17	10	13	19

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S452. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TRIOBP MUTATED	7	9	3
TRIOBP WILD-TYPE	16	24	19

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S453. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TRIOBP MUTATED	9	4	7
TRIOBP WILD-TYPE	28	12	19

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S454. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TRIOBP MUTATED	7	3	10
TRIOBP WILD-TYPE	19	7	33

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S455. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TRIOBP MUTATED	9	5	6
TRIOBP WILD-TYPE	29	13	17

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TRIOBP MUTATED	10	3	7
TRIOBP WILD-TYPE	31	8	20

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0196 (Chi-square test), Q value = 1

Table S457. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SARM1 MUTATED	8	1	0	4	1
SARM1 WILD-TYPE	24	22	15	6	8

Figure S27. Get High-res Image Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.471 (Chi-square test), Q value = 1

Table S458. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SARM1 MUTATED	0	2	3	3	1
SARM1 WILD-TYPE	18	9	18	15	10

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S459. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SARM1 MUTATED	3	1	3	2
SARM1 WILD-TYPE	21	13	14	21

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S460. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SARM1 MUTATED	2	4	3
SARM1 WILD-TYPE	21	29	19

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S461. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SARM1 MUTATED	3	3	3
SARM1 WILD-TYPE	34	13	23

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S462. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SARM1 MUTATED	3	2	4
SARM1 WILD-TYPE	23	8	39

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S463. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SARM1 MUTATED	3	4	2
SARM1 WILD-TYPE	35	14	21

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0591 (Fisher's exact test), Q value = 1

Table S464. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SARM1 MUTATED	2	3	4
SARM1 WILD-TYPE	39	8	23

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0188 (Chi-square test), Q value = 1

Table S465. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ERCC2 MUTATED	5	3	7	4	0
ERCC2 WILD-TYPE	27	20	8	6	9

Figure S28. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Chi-square test), Q value = 1

Table S466. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ERCC2 MUTATED	5	4	7	1	2
ERCC2 WILD-TYPE	13	7	14	17	9

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S467. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ERCC2 MUTATED	7	6	4	2
ERCC2 WILD-TYPE	17	8	13	21

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00307 (Fisher's exact test), Q value = 1

Table S468. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ERCC2 MUTATED	8	2	9
ERCC2 WILD-TYPE	15	31	13

Figure S29. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S469. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ERCC2 MUTATED	12	4	3
ERCC2 WILD-TYPE	25	12	23

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0678 (Fisher's exact test), Q value = 1

Table S470. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ERCC2 MUTATED	5	0	14
ERCC2 WILD-TYPE	21	10	29

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.077 (Fisher's exact test), Q value = 1

Table S471. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ERCC2 MUTATED	13	4	2
ERCC2 WILD-TYPE	25	14	21

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0388 (Fisher's exact test), Q value = 1

Table S472. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ERCC2 MUTATED	14	0	5
ERCC2 WILD-TYPE	27	11	22

Figure S30. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Chi-square test), Q value = 1

Table S473. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NEFH MUTATED	6	1	3	0	0
NEFH WILD-TYPE	26	22	12	10	9

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.382 (Chi-square test), Q value = 1

Table S474. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NEFH MUTATED	3	0	2	3	0
NEFH WILD-TYPE	15	11	19	15	11

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S475. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NEFH MUTATED	4	2	0	1
NEFH WILD-TYPE	20	12	17	22

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S476. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NEFH MUTATED	2	3	2
NEFH WILD-TYPE	21	30	20

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S477. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NEFH MUTATED	5	2	1
NEFH WILD-TYPE	32	14	25

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S478. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NEFH MUTATED	2	0	6
NEFH WILD-TYPE	24	10	37

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S479. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NEFH MUTATED	5	2	1
NEFH WILD-TYPE	33	16	22

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S480. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NEFH MUTATED	5	0	3
NEFH WILD-TYPE	36	11	24

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.344 (Chi-square test), Q value = 1

Table S481. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KBTBD13 MUTATED	6	6	1	2	0
KBTBD13 WILD-TYPE	26	17	14	8	9

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.467 (Chi-square test), Q value = 1

Table S482. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KBTBD13 MUTATED	3	2	2	4	4
KBTBD13 WILD-TYPE	15	9	19	14	7

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S483. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KBTBD13 MUTATED	6	2	2	5
KBTBD13 WILD-TYPE	18	12	15	18

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.101 (Fisher's exact test), Q value = 1

Table S484. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KBTBD13 MUTATED	6	8	1
KBTBD13 WILD-TYPE	17	25	21

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S485. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	30	14	20

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S486. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KBTBD13 MUTATED	6	2	7
KBTBD13 WILD-TYPE	20	8	36

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S487. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	31	16	17

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S488. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	34	9	21

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.315 (Chi-square test), Q value = 1

Table S489. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IRX3 MUTATED	10	2	5	2	2
IRX3 WILD-TYPE	22	21	10	8	7

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.538 (Chi-square test), Q value = 1

Table S490. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IRX3 MUTATED	2	3	5	3	4
IRX3 WILD-TYPE	16	8	16	15	7

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 1

Table S491. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IRX3 MUTATED	7	5	2	3
IRX3 WILD-TYPE	17	9	15	20

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S492. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IRX3 MUTATED	6	5	6
IRX3 WILD-TYPE	17	28	16

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S493. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IRX3 MUTATED	9	5	3
IRX3 WILD-TYPE	28	11	23

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S494. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IRX3 MUTATED	6	1	10
IRX3 WILD-TYPE	20	9	33

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S495. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IRX3 MUTATED	9	6	2
IRX3 WILD-TYPE	29	12	21

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S496. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IRX3 MUTATED	9	2	6
IRX3 WILD-TYPE	32	9	21

'MUC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.829 (Chi-square test), Q value = 1

Table S497. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MUC2 MUTATED	5	4	3	2	3
MUC2 WILD-TYPE	27	19	12	8	6

'MUC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0845 (Chi-square test), Q value = 1

Table S498. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MUC2 MUTATED	0	2	7	4	1
MUC2 WILD-TYPE	18	9	14	14	10

'MUC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.098 (Fisher's exact test), Q value = 1

Table S499. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MUC2 MUTATED	1	4	5	4
MUC2 WILD-TYPE	23	10	12	19

'MUC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0889 (Fisher's exact test), Q value = 1

Table S500. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MUC2 MUTATED	1	7	6
MUC2 WILD-TYPE	22	26	16

'MUC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S501. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MUC2 MUTATED	4	5	5
MUC2 WILD-TYPE	33	11	21

'MUC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0271 (Fisher's exact test), Q value = 1

Table S502. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MUC2 MUTATED	9	1	4
MUC2 WILD-TYPE	17	9	39

Figure S31. Get High-res Image Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'MUC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S503. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MUC2 MUTATED	4	6	4
MUC2 WILD-TYPE	34	12	19

'MUC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 1

Table S504. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MUC2 MUTATED	4	1	9
MUC2 WILD-TYPE	37	10	18

Figure S32. Get High-res Image Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.284 (Chi-square test), Q value = 1

Table S505. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GARS MUTATED	12	6	6	5	6
GARS WILD-TYPE	20	17	9	5	3

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.562 (Chi-square test), Q value = 1

Table S506. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GARS MUTATED	5	2	9	7	5
GARS WILD-TYPE	13	9	12	11	6

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S507. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GARS MUTATED	8	3	7	10
GARS WILD-TYPE	16	11	10	13

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S508. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GARS MUTATED	6	16	6
GARS WILD-TYPE	17	17	16

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S509. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GARS MUTATED	10	5	13
GARS WILD-TYPE	27	11	13

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0436 (Fisher's exact test), Q value = 1

Table S510. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GARS MUTATED	13	5	10
GARS WILD-TYPE	13	5	33

Figure S33. Get High-res Image Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S511. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GARS MUTATED	10	6	12
GARS WILD-TYPE	28	12	11

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0908 (Fisher's exact test), Q value = 1

Table S512. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GARS MUTATED	10	5	13
GARS WILD-TYPE	31	6	14

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.885 (Chi-square test), Q value = 1

Table S513. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
UQCRFS1 MUTATED	4	2	3	1	1
UQCRFS1 WILD-TYPE	28	21	12	9	8

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.429 (Chi-square test), Q value = 1

Table S514. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
UQCRFS1 MUTATED	4	1	5	1	1
UQCRFS1 WILD-TYPE	14	10	16	17	10

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S515. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
UQCRFS1 MUTATED	4	2	3	2
UQCRFS1 WILD-TYPE	20	12	14	21

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S516. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
UQCRFS1 MUTATED	4	3	4
UQCRFS1 WILD-TYPE	19	30	18

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S517. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
UQCRFS1 MUTATED	8	1	3
UQCRFS1 WILD-TYPE	29	15	23

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0717 (Fisher's exact test), Q value = 1

Table S518. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
UQCRFS1 MUTATED	1	3	8
UQCRFS1 WILD-TYPE	25	7	35

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S519. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
UQCRFS1 MUTATED	8	1	3
UQCRFS1 WILD-TYPE	30	17	20

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0653 (Fisher's exact test), Q value = 1

Table S520. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
UQCRFS1 MUTATED	8	3	1
UQCRFS1 WILD-TYPE	33	8	26

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S521. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATXN1 MUTATED	5	4	3	0	2
ATXN1 WILD-TYPE	27	19	12	10	7

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.178 (Chi-square test), Q value = 1

Table S522. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATXN1 MUTATED	1	4	2	2	2
ATXN1 WILD-TYPE	17	7	19	16	9

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S523. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATXN1 MUTATED	2	3	3	3
ATXN1 WILD-TYPE	22	11	14	20

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S524. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATXN1 MUTATED	3	4	4
ATXN1 WILD-TYPE	20	29	18

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S525. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATXN1 MUTATED	5	3	3
ATXN1 WILD-TYPE	32	13	23

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S526. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATXN1 MUTATED	3	1	7
ATXN1 WILD-TYPE	23	9	36

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S527. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATXN1 MUTATED	5	3	3
ATXN1 WILD-TYPE	33	15	20

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S528. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATXN1 MUTATED	7	1	3
ATXN1 WILD-TYPE	34	10	24

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0739 (Chi-square test), Q value = 1

Table S529. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF628 MUTATED	7	1	0	2	0
ZNF628 WILD-TYPE	25	22	15	8	9

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Chi-square test), Q value = 1

Table S530. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF628 MUTATED	3	2	1	1	0
ZNF628 WILD-TYPE	15	9	20	17	11

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0703 (Fisher's exact test), Q value = 1

Table S531. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF628 MUTATED	5	1	1	0
ZNF628 WILD-TYPE	19	13	16	23

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.059 (Fisher's exact test), Q value = 1

Table S532. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF628 MUTATED	5	1	1
ZNF628 WILD-TYPE	18	32	21

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0417 (Fisher's exact test), Q value = 1

Table S533. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF628 MUTATED	2	4	1
ZNF628 WILD-TYPE	35	12	25

Figure S34. Get High-res Image Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S534. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF628 MUTATED	4	0	3
ZNF628 WILD-TYPE	22	10	40

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0433 (Fisher's exact test), Q value = 1

Table S535. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF628 MUTATED	3	4	0
ZNF628 WILD-TYPE	35	14	23

Figure S35. Get High-res Image Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S536. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF628 MUTATED	3	0	4
ZNF628 WILD-TYPE	38	11	23

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S537. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DSPP MUTATED	5	4	3	1	0
DSPP WILD-TYPE	27	19	12	9	9

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.175 (Chi-square test), Q value = 1

Table S538. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DSPP MUTATED	1	4	2	3	1
DSPP WILD-TYPE	17	7	19	15	10

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S539. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DSPP MUTATED	3	3	2	3
DSPP WILD-TYPE	21	11	15	20

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S540. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DSPP MUTATED	4	4	3
DSPP WILD-TYPE	19	29	19

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S541. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DSPP MUTATED	5	3	3
DSPP WILD-TYPE	32	13	23

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S542. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DSPP MUTATED	4	0	7
DSPP WILD-TYPE	22	10	36

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S543. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DSPP MUTATED	5	4	2
DSPP WILD-TYPE	33	14	21

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S544. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DSPP MUTATED	7	0	4
DSPP WILD-TYPE	34	11	23

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.289 (Chi-square test), Q value = 1

Table S545. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ASPDH MUTATED	7	4	4	4	0
ASPDH WILD-TYPE	25	19	11	6	9

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.674 (Chi-square test), Q value = 1

Table S546. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ASPDH MUTATED	3	3	6	2	2
ASPDH WILD-TYPE	15	8	15	16	9

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0774 (Fisher's exact test), Q value = 1

Table S547. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ASPDH MUTATED	6	3	6	1
ASPDH WILD-TYPE	18	11	11	22

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0874 (Fisher's exact test), Q value = 1

Table S548. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ASPDH MUTATED	6	3	7
ASPDH WILD-TYPE	17	30	15

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S549. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ASPDH MUTATED	11	2	3
ASPDH WILD-TYPE	26	14	23

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00171 (Fisher's exact test), Q value = 1

Table S550. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ASPDH MUTATED	0	3	13
ASPDH WILD-TYPE	26	7	30

Figure S36. Get High-res Image Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0539 (Fisher's exact test), Q value = 1

Table S551. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ASPDH MUTATED	12	1	3
ASPDH WILD-TYPE	26	17	20

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00136 (Fisher's exact test), Q value = 1

Table S552. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ASPDH MUTATED	13	3	0
ASPDH WILD-TYPE	28	8	27

Figure S37. Get High-res Image Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.312 (Chi-square test), Q value = 1

Table S553. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CSGALNACT2 MUTATED	1	3	0	0	1
CSGALNACT2 WILD-TYPE	31	20	15	10	8

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0371 (Chi-square test), Q value = 1

Table S554. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CSGALNACT2 MUTATED	1	0	1	0	3
CSGALNACT2 WILD-TYPE	17	11	20	18	8

Figure S38. Get High-res Image Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S555. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CSGALNACT2 MUTATED	1	0	2	2
CSGALNACT2 WILD-TYPE	23	14	15	21

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S556. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CSGALNACT2 MUTATED	1	4	0
CSGALNACT2 WILD-TYPE	22	29	22

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S557. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CSGALNACT2 MUTATED	1	0	4
CSGALNACT2 WILD-TYPE	36	16	22

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 1

Table S558. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CSGALNACT2 MUTATED	3	1	1
CSGALNACT2 WILD-TYPE	23	9	42

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S559. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CSGALNACT2 MUTATED	1	1	3
CSGALNACT2 WILD-TYPE	37	17	20

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S560. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CSGALNACT2 MUTATED	1	1	3
CSGALNACT2 WILD-TYPE	40	10	24

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.297 (Chi-square test), Q value = 1

Table S561. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TPO MUTATED	11	3	2	2	3
TPO WILD-TYPE	21	20	13	8	6

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.102 (Chi-square test), Q value = 1

Table S562. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TPO MUTATED	5	5	1	5	2
TPO WILD-TYPE	13	6	20	13	9

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S563. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TPO MUTATED	9	3	2	4
TPO WILD-TYPE	15	11	15	19

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S564. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TPO MUTATED	8	7	3
TPO WILD-TYPE	15	26	19

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S565. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TPO MUTATED	8	6	4
TPO WILD-TYPE	29	10	22

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S566. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TPO MUTATED	6	2	10
TPO WILD-TYPE	20	8	33

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S567. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TPO MUTATED	8	7	3
TPO WILD-TYPE	30	11	20

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S568. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TPO MUTATED	8	3	7
TPO WILD-TYPE	33	8	20

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Chi-square test), Q value = 1

Table S569. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP4-5 MUTATED	2	4	0	0	1
KRTAP4-5 WILD-TYPE	30	19	15	10	8

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.115 (Chi-square test), Q value = 1

Table S570. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP4-5 MUTATED	1	3	1	1	0
KRTAP4-5 WILD-TYPE	17	8	20	17	11

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.722 (Fisher's exact test), Q value = 1

Table S571. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP4-5 MUTATED	2	0	2	2
KRTAP4-5 WILD-TYPE	22	14	15	21

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S572. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP4-5 MUTATED	2	3	1
KRTAP4-5 WILD-TYPE	21	30	21

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S573. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP4-5 MUTATED	2	1	3
KRTAP4-5 WILD-TYPE	35	15	23

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S574. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP4-5 MUTATED	1	2	3
KRTAP4-5 WILD-TYPE	25	8	40

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S575. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP4-5 MUTATED	2	1	3
KRTAP4-5 WILD-TYPE	36	17	20

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S576. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP4-5 MUTATED	3	2	1
KRTAP4-5 WILD-TYPE	38	9	26

'GLTSCR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.504 (Chi-square test), Q value = 1

Table S577. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLTSCR2 MUTATED	5	1	1	1	0
GLTSCR2 WILD-TYPE	27	22	14	9	9

'GLTSCR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.173 (Chi-square test), Q value = 1

Table S578. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLTSCR2 MUTATED	4	0	2	1	0
GLTSCR2 WILD-TYPE	14	11	19	17	11

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S579. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLTSCR2 MUTATED	4	1	2	0
GLTSCR2 WILD-TYPE	20	13	15	23

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S580. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLTSCR2 MUTATED	3	2	2
GLTSCR2 WILD-TYPE	20	31	20

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 1

Table S581. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLTSCR2 MUTATED	2	3	2
GLTSCR2 WILD-TYPE	35	13	24

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S582. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLTSCR2 MUTATED	4	1	2
GLTSCR2 WILD-TYPE	22	9	41

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S583. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLTSCR2 MUTATED	2	4	1
GLTSCR2 WILD-TYPE	36	14	22

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S584. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLTSCR2 MUTATED	2	1	4
GLTSCR2 WILD-TYPE	39	10	23

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S585. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PANK2 MUTATED	7	2	2	2	2
PANK2 WILD-TYPE	25	21	13	8	7

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.802 (Chi-square test), Q value = 1

Table S586. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PANK2 MUTATED	3	1	2	4	2
PANK2 WILD-TYPE	15	10	19	14	9

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S587. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PANK2 MUTATED	5	1	2	4
PANK2 WILD-TYPE	19	13	15	19

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S588. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PANK2 MUTATED	4	6	2
PANK2 WILD-TYPE	19	27	20

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PANK2 MUTATED	6	2	4
PANK2 WILD-TYPE	31	14	22

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S590. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PANK2 MUTATED	3	2	7
PANK2 WILD-TYPE	23	8	36

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S591. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PANK2 MUTATED	6	3	3
PANK2 WILD-TYPE	32	15	20

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S592. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PANK2 MUTATED	5	3	4
PANK2 WILD-TYPE	36	8	23

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Chi-square test), Q value = 1

Table S593. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF39 MUTATED	2	1	2	2	0
RNF39 WILD-TYPE	30	22	13	8	9

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Chi-square test), Q value = 1

Table S594. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF39 MUTATED	1	2	4	0	0
RNF39 WILD-TYPE	17	9	17	18	11

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0334 (Fisher's exact test), Q value = 1

Table S595. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF39 MUTATED	1	2	4	0
RNF39 WILD-TYPE	23	12	13	23

Figure S39. Get High-res Image Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00798 (Fisher's exact test), Q value = 1

Table S596. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF39 MUTATED	2	0	5
RNF39 WILD-TYPE	21	33	17

Figure S40. Get High-res Image Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0544 (Fisher's exact test), Q value = 1

Table S597. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF39 MUTATED	4	3	0
RNF39 WILD-TYPE	33	13	26

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S598. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF39 MUTATED	2	0	5
RNF39 WILD-TYPE	24	10	38

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S599. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF39 MUTATED	4	3	0
RNF39 WILD-TYPE	34	15	23

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S600. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF39 MUTATED	5	0	2
RNF39 WILD-TYPE	36	11	25

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.275 (Chi-square test), Q value = 1

Table S601. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MAL2 MUTATED	7	8	6	1	1
MAL2 WILD-TYPE	25	15	9	9	8

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.782 (Chi-square test), Q value = 1

Table S602. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MAL2 MUTATED	3	3	3	5	3
MAL2 WILD-TYPE	15	8	18	13	8

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0202 (Fisher's exact test), Q value = 1

Table S603. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MAL2 MUTATED	5	6	0	6
MAL2 WILD-TYPE	19	8	17	17

Figure S41. Get High-res Image Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S604. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MAL2 MUTATED	5	7	5
MAL2 WILD-TYPE	18	26	17

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S605. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MAL2 MUTATED	6	5	6
MAL2 WILD-TYPE	31	11	20

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S606. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MAL2 MUTATED	7	2	8
MAL2 WILD-TYPE	19	8	35

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S607. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MAL2 MUTATED	7	4	6
MAL2 WILD-TYPE	31	14	17

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S608. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MAL2 MUTATED	8	2	7
MAL2 WILD-TYPE	33	9	20

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.252 (Chi-square test), Q value = 1

Table S609. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZAR1 MUTATED	6	5	1	3	4
ZAR1 WILD-TYPE	26	18	14	7	5

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.634 (Chi-square test), Q value = 1

Table S610. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZAR1 MUTATED	3	3	3	4	4
ZAR1 WILD-TYPE	15	8	18	14	7

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S611. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZAR1 MUTATED	6	1	4	6
ZAR1 WILD-TYPE	18	13	13	17

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S612. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZAR1 MUTATED	6	8	3
ZAR1 WILD-TYPE	17	25	19

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S613. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZAR1 MUTATED	9	1	7
ZAR1 WILD-TYPE	28	15	19

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S614. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZAR1 MUTATED	6	2	9
ZAR1 WILD-TYPE	20	8	34

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S615. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZAR1 MUTATED	9	2	6
ZAR1 WILD-TYPE	29	16	17

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S616. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZAR1 MUTATED	8	3	6
ZAR1 WILD-TYPE	33	8	21

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.734 (Chi-square test), Q value = 1

Table S617. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C16ORF3 MUTATED	3	3	0	1	1
C16ORF3 WILD-TYPE	29	20	15	9	8

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00275 (Chi-square test), Q value = 1

Table S618. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C16ORF3 MUTATED	0	4	1	0	1
C16ORF3 WILD-TYPE	18	7	20	18	10

Figure S42. Get High-res Image Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S619. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C16ORF3 MUTATED	1	1	3	1
C16ORF3 WILD-TYPE	23	13	14	22

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S620. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	21	31	20

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S621. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	35	14	24

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S622. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C16ORF3 MUTATED	2	1	3
C16ORF3 WILD-TYPE	24	9	40

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S623. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	36	16	21

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S624. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C16ORF3 MUTATED	3	1	2
C16ORF3 WILD-TYPE	38	10	25

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S625. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP5-5 MUTATED	3	1	1	2	0
KRTAP5-5 WILD-TYPE	29	22	14	8	9

'KRTAP5-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S626. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP5-5 MUTATED	2	0	1	2	0
KRTAP5-5 WILD-TYPE	16	11	20	16	11

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S627. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP5-5 MUTATED	3	1	0	1
KRTAP5-5 WILD-TYPE	21	13	17	22

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S628. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	21	31	21

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S629. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	35	14	25

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S630. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP5-5 MUTATED	2	1	2
KRTAP5-5 WILD-TYPE	24	9	41

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S631. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	36	16	22

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S632. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP5-5 MUTATED	2	1	2
KRTAP5-5 WILD-TYPE	39	10	25

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.378 (Chi-square test), Q value = 1

Table S633. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CRIPAK MUTATED	4	5	2	4	2
CRIPAK WILD-TYPE	28	18	13	6	7

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.566 (Chi-square test), Q value = 1

Table S634. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CRIPAK MUTATED	3	2	4	2	4
CRIPAK WILD-TYPE	15	9	17	16	7

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S635. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CRIPAK MUTATED	5	0	5	5
CRIPAK WILD-TYPE	19	14	12	18

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S636. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CRIPAK MUTATED	5	7	3
CRIPAK WILD-TYPE	18	26	19

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S637. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	29	14	21

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S638. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CRIPAK MUTATED	5	2	8
CRIPAK WILD-TYPE	21	8	35

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S639. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	30	16	18

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S640. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	33	9	22

'C14ORF180 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S641. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C14ORF180 MUTATED	2	0	1	1	0
C14ORF180 WILD-TYPE	30	23	14	9	9

'C14ORF180 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0794 (Chi-square test), Q value = 1

Table S642. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C14ORF180 MUTATED	0	0	0	1	2
C14ORF180 WILD-TYPE	18	11	21	17	9

'C14ORF180 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S643. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C14ORF180 MUTATED	0	1	1	1
C14ORF180 WILD-TYPE	24	13	16	22

'C14ORF180 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S644. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C14ORF180 MUTATED	0	2	1
C14ORF180 WILD-TYPE	23	31	21

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S645. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C14ORF180 MUTATED	3	0	0
C14ORF180 WILD-TYPE	34	16	26

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S646. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C14ORF180 MUTATED	0	0	3
C14ORF180 WILD-TYPE	26	10	40

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S647. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C14ORF180 MUTATED	3	0	0
C14ORF180 WILD-TYPE	35	18	23

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S648. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C14ORF180 MUTATED	2	1	0
C14ORF180 WILD-TYPE	39	10	27

'SPERT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.463 (Chi-square test), Q value = 1

Table S649. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SPERT MUTATED	1	2	2	0	0
SPERT WILD-TYPE	31	21	13	10	9

'SPERT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S650. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SPERT MUTATED	0	1	2	1	0
SPERT WILD-TYPE	18	10	19	17	11

'SPERT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 1

Table S651. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SPERT MUTATED	0	1	3	0
SPERT WILD-TYPE	24	13	14	23

Figure S43. Get High-res Image Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SPERT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S652. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SPERT MUTATED	0	1	3
SPERT WILD-TYPE	23	32	19

'SPERT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S653. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	33	16	26

'SPERT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S654. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SPERT MUTATED	0	0	4
SPERT WILD-TYPE	26	10	39

'SPERT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S655. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	34	18	23

'SPERT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S656. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	37	11	27

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0173 (Chi-square test), Q value = 1

Table S657. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TP53 MUTATED	5	1	5	5	1
TP53 WILD-TYPE	27	22	10	5	8

Figure S44. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.519 (Chi-square test), Q value = 1

Table S658. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TP53 MUTATED	3	3	6	2	1
TP53 WILD-TYPE	15	8	15	16	10

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00344 (Fisher's exact test), Q value = 1

Table S659. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TP53 MUTATED	4	4	7	0
TP53 WILD-TYPE	20	10	10	23

Figure S45. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S660. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TP53 MUTATED	5	3	7
TP53 WILD-TYPE	18	30	15

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00268 (Fisher's exact test), Q value = 1

Table S661. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TP53 MUTATED	10	5	0
TP53 WILD-TYPE	27	11	26

Figure S46. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.07 (Fisher's exact test), Q value = 1

Table S662. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TP53 MUTATED	3	0	12
TP53 WILD-TYPE	23	10	31

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00936 (Fisher's exact test), Q value = 1

Table S663. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TP53 MUTATED	10	5	0
TP53 WILD-TYPE	28	13	23

Figure S47. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0373 (Fisher's exact test), Q value = 1

Table S664. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TP53 MUTATED	12	0	3
TP53 WILD-TYPE	29	11	24

Figure S48. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'B3GNT6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.32 (Chi-square test), Q value = 1

Table S665. Gene #84: 'B3GNT6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
B3GNT6 MUTATED	3	0	0	1	0
B3GNT6 WILD-TYPE	29	23	15	9	9

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0312 (Chi-square test), Q value = 1

Table S666. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BHLHE22 MUTATED	2	3	5	0	0
BHLHE22 WILD-TYPE	30	20	10	10	9

Figure S49. Get High-res Image Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.27 (Chi-square test), Q value = 1

Table S667. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BHLHE22 MUTATED	0	3	3	3	1
BHLHE22 WILD-TYPE	18	8	18	15	10

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00963 (Fisher's exact test), Q value = 1

Table S668. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BHLHE22 MUTATED	0	5	2	3
BHLHE22 WILD-TYPE	24	9	15	20

Figure S50. Get High-res Image Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S669. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BHLHE22 MUTATED	2	3	5
BHLHE22 WILD-TYPE	21	30	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S670. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BHLHE22 MUTATED	4	3	3
BHLHE22 WILD-TYPE	33	13	23

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S671. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BHLHE22 MUTATED	4	1	5
BHLHE22 WILD-TYPE	22	9	38

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S672. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BHLHE22 MUTATED	4	3	3
BHLHE22 WILD-TYPE	34	15	20

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S673. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BHLHE22 MUTATED	5	1	4
BHLHE22 WILD-TYPE	36	10	23

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.186 (Chi-square test), Q value = 1

Table S674. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RGMB MUTATED	4	2	4	0	0
RGMB WILD-TYPE	28	21	11	10	9

'RGMB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.831 (Chi-square test), Q value = 1

Table S675. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RGMB MUTATED	2	0	2	1	1
RGMB WILD-TYPE	16	11	19	17	10

'RGMB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S676. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RGMB MUTATED	2	1	2	1
RGMB WILD-TYPE	22	13	15	22

'RGMB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S677. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RGMB MUTATED	2	1	3
RGMB WILD-TYPE	21	32	19

'RGMB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S678. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RGMB MUTATED	3	2	1
RGMB WILD-TYPE	34	14	25

'RGMB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S679. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RGMB MUTATED	2	1	3
RGMB WILD-TYPE	24	9	40

'RGMB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S680. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RGMB MUTATED	3	2	1
RGMB WILD-TYPE	35	16	22

'RGMB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S681. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RGMB MUTATED	3	1	2
RGMB WILD-TYPE	38	10	25

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0848 (Chi-square test), Q value = 1

Table S682. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
APOE MUTATED	1	3	1	3	0
APOE WILD-TYPE	31	20	14	7	9

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.342 (Chi-square test), Q value = 1

Table S683. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
APOE MUTATED	1	0	3	3	0
APOE WILD-TYPE	17	11	18	15	11

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S684. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
APOE MUTATED	2	0	4	1
APOE WILD-TYPE	22	14	13	22

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S685. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
APOE MUTATED	1	3	3
APOE WILD-TYPE	22	30	19

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 1

Table S686. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
APOE MUTATED	2	3	2
APOE WILD-TYPE	35	13	24

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S687. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
APOE MUTATED	4	0	3
APOE WILD-TYPE	22	10	40

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S688. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
APOE MUTATED	2	4	1
APOE WILD-TYPE	36	14	22

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S689. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
APOE MUTATED	3	0	4
APOE WILD-TYPE	38	11	23

'PCGF6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.497 (Chi-square test), Q value = 1

Table S690. Gene #88: 'PCGF6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PCGF6 MUTATED	3	1	0	0	0
PCGF6 WILD-TYPE	29	22	15	10	9

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.384 (Chi-square test), Q value = 1

Table S691. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MEN1 MUTATED	1	1	2	2	1
MEN1 WILD-TYPE	31	22	13	8	8

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0105 (Chi-square test), Q value = 1

Table S692. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MEN1 MUTATED	0	3	5	0	0
MEN1 WILD-TYPE	18	8	16	18	11

Figure S51. Get High-res Image Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S693. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MEN1 MUTATED	1	2	4	1
MEN1 WILD-TYPE	23	12	13	22

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.014 (Fisher's exact test), Q value = 1

Table S694. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MEN1 MUTATED	1	1	6
MEN1 WILD-TYPE	22	32	16

Figure S52. Get High-res Image Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S695. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MEN1 MUTATED	5	2	1
MEN1 WILD-TYPE	32	14	25

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S696. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MEN1 MUTATED	1	1	6
MEN1 WILD-TYPE	25	9	37

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S697. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MEN1 MUTATED	5	2	1
MEN1 WILD-TYPE	33	16	22

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S698. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MEN1 MUTATED	6	1	1
MEN1 WILD-TYPE	35	10	26

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.241 (Chi-square test), Q value = 1

Table S699. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LZTR1 MUTATED	5	0	1	1	0
LZTR1 WILD-TYPE	27	23	14	9	9

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Chi-square test), Q value = 1

Table S700. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LZTR1 MUTATED	3	0	1	1	0
LZTR1 WILD-TYPE	15	11	20	17	11

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 1

Table S701. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LZTR1 MUTATED	4	1	0	0
LZTR1 WILD-TYPE	20	13	17	23

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S702. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LZTR1 MUTATED	3	1	1
LZTR1 WILD-TYPE	20	32	21

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S703. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LZTR1 MUTATED	4	1	0
LZTR1 WILD-TYPE	33	15	26

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S704. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LZTR1 MUTATED	0	0	5
LZTR1 WILD-TYPE	26	10	38

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S705. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LZTR1 MUTATED	4	1	0
LZTR1 WILD-TYPE	34	17	23

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S706. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LZTR1 MUTATED	4	0	1
LZTR1 WILD-TYPE	37	11	26

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.337 (Chi-square test), Q value = 1

Table S707. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RASIP1 MUTATED	4	2	4	0	1
RASIP1 WILD-TYPE	28	21	11	10	8

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.735 (Chi-square test), Q value = 1

Table S708. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RASIP1 MUTATED	3	2	4	1	1
RASIP1 WILD-TYPE	15	9	17	17	10

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 1

Table S709. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RASIP1 MUTATED	4	4	3	0
RASIP1 WILD-TYPE	20	10	14	23

Figure S53. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 1

Table S710. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RASIP1 MUTATED	4	2	5
RASIP1 WILD-TYPE	19	31	17

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0118 (Fisher's exact test), Q value = 1

Table S711. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RASIP1 MUTATED	4	6	1
RASIP1 WILD-TYPE	33	10	25

Figure S54. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S712. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RASIP1 MUTATED	6	0	5
RASIP1 WILD-TYPE	20	10	38

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00128 (Fisher's exact test), Q value = 1

Table S713. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RASIP1 MUTATED	4	7	0
RASIP1 WILD-TYPE	34	11	23

Figure S55. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S714. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RASIP1 MUTATED	5	0	6
RASIP1 WILD-TYPE	36	11	21

'ZC3H12D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0274 (Chi-square test), Q value = 1

Table S715. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZC3H12D MUTATED	2	0	1	3	0
ZC3H12D WILD-TYPE	30	23	14	7	9

Figure S56. Get High-res Image Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ZC3H12D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S716. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZC3H12D MUTATED	1	0	2	1	1
ZC3H12D WILD-TYPE	17	11	19	17	10

'ZC3H12D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S717. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZC3H12D MUTATED	1	1	2	1
ZC3H12D WILD-TYPE	23	13	15	22

'ZC3H12D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S718. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZC3H12D MUTATED	1	1	3
ZC3H12D WILD-TYPE	22	32	19

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S719. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZC3H12D MUTATED	4	0	1
ZC3H12D WILD-TYPE	33	16	25

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S720. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZC3H12D MUTATED	0	1	4
ZC3H12D WILD-TYPE	26	9	39

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S721. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZC3H12D MUTATED	4	0	1
ZC3H12D WILD-TYPE	34	18	22

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 1

Table S722. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZC3H12D MUTATED	3	2	0
ZC3H12D WILD-TYPE	38	9	27

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.372 (Chi-square test), Q value = 1

Table S723. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TSC22D2 MUTATED	4	1	2	3	1
TSC22D2 WILD-TYPE	28	22	13	7	8

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.275 (Chi-square test), Q value = 1

Table S724. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TSC22D2 MUTATED	2	0	5	1	2
TSC22D2 WILD-TYPE	16	11	16	17	9

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S725. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TSC22D2 MUTATED	3	1	3	3
TSC22D2 WILD-TYPE	21	13	14	20

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S726. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TSC22D2 MUTATED	2	4	4
TSC22D2 WILD-TYPE	21	29	18

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S727. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TSC22D2 MUTATED	5	2	3
TSC22D2 WILD-TYPE	32	14	23

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S728. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TSC22D2 MUTATED	3	0	7
TSC22D2 WILD-TYPE	23	10	36

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S729. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TSC22D2 MUTATED	5	2	3
TSC22D2 WILD-TYPE	33	16	20

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S730. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TSC22D2 MUTATED	6	0	4
TSC22D2 WILD-TYPE	35	11	23

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.081 (Chi-square test), Q value = 1

Table S731. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
COQ2 MUTATED	1	1	1	3	1
COQ2 WILD-TYPE	31	22	14	7	8

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Chi-square test), Q value = 1

Table S732. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
COQ2 MUTATED	1	1	1	1	2
COQ2 WILD-TYPE	17	10	20	17	9

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S733. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
COQ2 MUTATED	1	2	2	1
COQ2 WILD-TYPE	23	12	15	22

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S734. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
COQ2 MUTATED	1	2	3
COQ2 WILD-TYPE	22	31	19

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S735. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
COQ2 MUTATED	3	2	1
COQ2 WILD-TYPE	34	14	25

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S736. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
COQ2 MUTATED	3	0	3
COQ2 WILD-TYPE	23	10	40

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S737. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
COQ2 MUTATED	3	2	1
COQ2 WILD-TYPE	35	16	22

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S738. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
COQ2 MUTATED	3	0	3
COQ2 WILD-TYPE	38	11	24

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.218 (Chi-square test), Q value = 1

Table S739. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DLEU7 MUTATED	4	0	2	0	0
DLEU7 WILD-TYPE	28	23	13	10	9

'DLEU7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.788 (Chi-square test), Q value = 1

Table S740. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DLEU7 MUTATED	1	1	1	0	1
DLEU7 WILD-TYPE	17	10	20	18	10

'DLEU7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S741. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DLEU7 MUTATED	2	1	1	0
DLEU7 WILD-TYPE	22	13	16	23

'DLEU7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S742. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DLEU7 MUTATED	2	0	2
DLEU7 WILD-TYPE	21	33	20

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S743. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DLEU7 MUTATED	3	1	0
DLEU7 WILD-TYPE	34	15	26

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S744. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DLEU7 MUTATED	1	0	3
DLEU7 WILD-TYPE	25	10	40

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S745. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DLEU7 MUTATED	3	1	0
DLEU7 WILD-TYPE	35	17	23

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S746. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DLEU7 MUTATED	3	0	1
DLEU7 WILD-TYPE	38	11	26

'FAM46A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S747. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FAM46A MUTATED	1	2	1	0	0
FAM46A WILD-TYPE	31	21	14	10	9

'FAM46A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S748. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FAM46A MUTATED	1	0	1	1	0
FAM46A WILD-TYPE	17	11	20	17	11

'FAM46A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S749. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FAM46A MUTATED	1	1	0	1
FAM46A WILD-TYPE	23	13	17	22

'FAM46A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S750. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FAM46A MUTATED	1	1	1
FAM46A WILD-TYPE	22	32	21

'FAM46A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S751. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	35	16	25

'FAM46A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S752. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FAM46A MUTATED	1	0	2
FAM46A WILD-TYPE	25	10	41

'FAM46A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S753. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	36	18	22

'FAM46A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S754. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	39	11	26

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.634 (Chi-square test), Q value = 1

Table S755. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
JMJD4 MUTATED	2	2	2	0	0
JMJD4 WILD-TYPE	30	21	13	10	9

'JMJD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.177 (Chi-square test), Q value = 1

Table S756. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
JMJD4 MUTATED	3	0	2	0	0
JMJD4 WILD-TYPE	15	11	19	18	11

'JMJD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S757. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
JMJD4 MUTATED	3	1	1	0
JMJD4 WILD-TYPE	21	13	16	23

'JMJD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S758. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	20	32	21

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S759. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	34	15	25

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S760. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
JMJD4 MUTATED	1	1	3
JMJD4 WILD-TYPE	25	9	40

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	35	17	22

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S762. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	38	10	26

'DOK7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Chi-square test), Q value = 1

Table S763. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DOK7 MUTATED	2	1	1	2	1
DOK7 WILD-TYPE	30	22	14	8	8

'DOK7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.373 (Chi-square test), Q value = 1

Table S764. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DOK7 MUTATED	1	0	4	1	1
DOK7 WILD-TYPE	17	11	17	17	10

'DOK7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S765. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DOK7 MUTATED	2	1	2	2
DOK7 WILD-TYPE	22	13	15	21

'DOK7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S766. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DOK7 MUTATED	2	3	2
DOK7 WILD-TYPE	21	30	20

'DOK7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S767. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DOK7 MUTATED	3	1	3
DOK7 WILD-TYPE	34	15	23

'DOK7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0198 (Fisher's exact test), Q value = 1

Table S768. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DOK7 MUTATED	0	3	4
DOK7 WILD-TYPE	26	7	39

Figure S57. Get High-res Image Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'DOK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S769. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DOK7 MUTATED	3	1	3
DOK7 WILD-TYPE	35	17	20

'DOK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.02 (Fisher's exact test), Q value = 1

Table S770. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DOK7 MUTATED	4	3	0
DOK7 WILD-TYPE	37	8	27

Figure S58. Get High-res Image Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.775 (Chi-square test), Q value = 1

Table S771. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KNDC1 MUTATED	4	4	3	3	2
KNDC1 WILD-TYPE	28	19	12	7	7

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0847 (Chi-square test), Q value = 1

Table S772. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KNDC1 MUTATED	1	2	4	2	5
KNDC1 WILD-TYPE	17	9	17	16	6

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S773. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KNDC1 MUTATED	3	4	2	5
KNDC1 WILD-TYPE	21	10	15	18

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S774. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KNDC1 MUTATED	3	8	3
KNDC1 WILD-TYPE	20	25	19

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S775. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KNDC1 MUTATED	5	3	6
KNDC1 WILD-TYPE	32	13	20

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S776. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KNDC1 MUTATED	6	2	6
KNDC1 WILD-TYPE	20	8	37

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S777. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KNDC1 MUTATED	5	4	5
KNDC1 WILD-TYPE	33	14	18

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S778. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KNDC1 MUTATED	6	2	6
KNDC1 WILD-TYPE	35	9	21

'SIX6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00409 (Chi-square test), Q value = 1

Table S779. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SIX6 MUTATED	0	0	3	0	0
SIX6 WILD-TYPE	32	23	12	10	9

Figure S59. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SIX6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0715 (Chi-square test), Q value = 1

Table S780. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SIX6 MUTATED	0	0	3	0	0
SIX6 WILD-TYPE	18	11	18	18	11

'SIX6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00478 (Fisher's exact test), Q value = 1

Table S781. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SIX6 MUTATED	0	3	0	0
SIX6 WILD-TYPE	24	11	17	23

Figure S60. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SIX6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0202 (Fisher's exact test), Q value = 1

Table S782. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SIX6 MUTATED	0	0	3
SIX6 WILD-TYPE	23	33	19

Figure S61. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'SIX6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S783. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	34	16	26

'SIX6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S784. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SIX6 MUTATED	0	0	3
SIX6 WILD-TYPE	26	10	40

'SIX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S785. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	35	18	23

'SIX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S786. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	38	11	27

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0684 (Chi-square test), Q value = 1

Table S787. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PDCD6 MUTATED	0	1	3	1	0
PDCD6 WILD-TYPE	32	22	12	9	9

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.482 (Chi-square test), Q value = 1

Table S788. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PDCD6 MUTATED	1	0	1	1	2
PDCD6 WILD-TYPE	17	11	20	17	9

'PDCD6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S789. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PDCD6 MUTATED	0	1	2	1
PDCD6 WILD-TYPE	24	13	15	22

'PDCD6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S790. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PDCD6 MUTATED	0	2	2
PDCD6 WILD-TYPE	23	31	20

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S791. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	33	16	25

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S792. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PDCD6 MUTATED	1	0	4
PDCD6 WILD-TYPE	25	10	39

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S793. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	34	18	22

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S794. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	37	11	26

'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.292 (Chi-square test), Q value = 1

Table S795. Gene #102: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HNRNPCL1 MUTATED	3	0	0	0	1
HNRNPCL1 WILD-TYPE	29	23	15	10	8

'ATP6V0E2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Chi-square test), Q value = 1

Table S796. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATP6V0E2 MUTATED	2	1	0	1	0
ATP6V0E2 WILD-TYPE	30	22	15	9	9

'ATP6V0E2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S797. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATP6V0E2 MUTATED	1	0	2	1	0
ATP6V0E2 WILD-TYPE	17	11	19	17	11

'ATP6V0E2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S798. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATP6V0E2 MUTATED	1	0	2	1
ATP6V0E2 WILD-TYPE	23	14	15	22

'ATP6V0E2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S799. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATP6V0E2 MUTATED	1	3	0
ATP6V0E2 WILD-TYPE	22	30	22

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0883 (Fisher's exact test), Q value = 1

Table S800. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATP6V0E2 MUTATED	0	1	3
ATP6V0E2 WILD-TYPE	37	15	23

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S801. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATP6V0E2 MUTATED	2	1	1
ATP6V0E2 WILD-TYPE	24	9	42

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S802. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATP6V0E2 MUTATED	1	0	3
ATP6V0E2 WILD-TYPE	37	18	20

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S803. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATP6V0E2 MUTATED	1	1	2
ATP6V0E2 WILD-TYPE	40	10	25

'HES3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S804. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HES3 MUTATED	3	1	1	2	0
HES3 WILD-TYPE	29	22	14	8	9

'HES3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.794 (Chi-square test), Q value = 1

Table S805. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HES3 MUTATED	2	0	1	1	1
HES3 WILD-TYPE	16	11	20	17	10

'HES3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S806. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HES3 MUTATED	3	1	0	1
HES3 WILD-TYPE	21	13	17	22

'HES3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S807. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HES3 MUTATED	3	1	1
HES3 WILD-TYPE	20	32	21

'HES3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S808. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HES3 MUTATED	3	2	0
HES3 WILD-TYPE	34	14	26

'HES3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S809. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HES3 MUTATED	2	0	3
HES3 WILD-TYPE	24	10	40

'HES3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S810. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HES3 MUTATED	3	2	0
HES3 WILD-TYPE	35	16	23

'HES3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S811. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HES3 MUTATED	3	0	2
HES3 WILD-TYPE	38	11	25

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.518 (Chi-square test), Q value = 1

Table S812. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AATK MUTATED	1	4	2	1	1
AATK WILD-TYPE	31	19	13	9	8

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Chi-square test), Q value = 1

Table S813. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AATK MUTATED	1	1	4	0	1
AATK WILD-TYPE	17	10	17	18	10

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S814. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AATK MUTATED	1	2	2	2
AATK WILD-TYPE	23	12	15	21

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S815. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AATK MUTATED	1	2	4
AATK WILD-TYPE	22	31	18

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S816. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AATK MUTATED	4	1	2
AATK WILD-TYPE	33	15	24

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S817. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AATK MUTATED	3	0	4
AATK WILD-TYPE	23	10	39

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S818. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AATK MUTATED	4	1	2
AATK WILD-TYPE	34	17	21

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S819. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AATK MUTATED	4	0	3
AATK WILD-TYPE	37	11	24

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.863 (Chi-square test), Q value = 1

Table S820. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FANK1 MUTATED	2	1	1	0	0
FANK1 WILD-TYPE	30	22	14	10	9

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.496 (Chi-square test), Q value = 1

Table S821. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FANK1 MUTATED	0	1	0	1	1
FANK1 WILD-TYPE	18	10	21	17	10

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S822. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	23	13	17	22

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S823. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FANK1 MUTATED	1	2	0
FANK1 WILD-TYPE	22	31	22

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S824. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	36	15	25

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S825. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FANK1 MUTATED	0	1	2
FANK1 WILD-TYPE	26	9	41

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S826. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	37	17	22

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S827. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FANK1 MUTATED	2	1	0
FANK1 WILD-TYPE	39	10	27

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.809 (Chi-square test), Q value = 1

Table S828. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FEZ2 MUTATED	2	2	1	0	0
FEZ2 WILD-TYPE	30	21	14	10	9

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.982 (Chi-square test), Q value = 1

Table S829. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FEZ2 MUTATED	1	1	1	1	1
FEZ2 WILD-TYPE	17	10	20	17	10

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S830. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FEZ2 MUTATED	1	1	0	3
FEZ2 WILD-TYPE	23	13	17	20

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S831. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FEZ2 MUTATED	2	3	0
FEZ2 WILD-TYPE	21	30	22

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S832. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	36	14	24

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S833. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FEZ2 MUTATED	2	1	2
FEZ2 WILD-TYPE	24	9	41

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S834. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	37	16	21

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S835. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	40	9	25

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.809 (Chi-square test), Q value = 1

Table S836. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HSD17B1 MUTATED	2	2	1	0	0
HSD17B1 WILD-TYPE	30	21	14	10	9

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.246 (Chi-square test), Q value = 1

Table S837. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HSD17B1 MUTATED	0	0	1	3	1
HSD17B1 WILD-TYPE	18	11	20	15	10

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S838. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HSD17B1 MUTATED	2	1	1	1
HSD17B1 WILD-TYPE	22	13	16	22

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S839. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HSD17B1 MUTATED	0	4	1
HSD17B1 WILD-TYPE	23	29	21

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S840. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HSD17B1 MUTATED	2	2	1
HSD17B1 WILD-TYPE	35	14	25

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S841. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HSD17B1 MUTATED	2	0	3
HSD17B1 WILD-TYPE	24	10	40

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S842. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HSD17B1 MUTATED	2	2	1
HSD17B1 WILD-TYPE	36	16	22

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S843. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HSD17B1 MUTATED	2	0	3
HSD17B1 WILD-TYPE	39	11	24

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Chi-square test), Q value = 1

Table S844. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRKAR1A MUTATED	2	1	1	2	1
PRKAR1A WILD-TYPE	30	22	14	8	8

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.794 (Chi-square test), Q value = 1

Table S845. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRKAR1A MUTATED	1	1	2	1	2
PRKAR1A WILD-TYPE	17	10	19	17	9

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 1

Table S846. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRKAR1A MUTATED	2	1	4	0
PRKAR1A WILD-TYPE	22	13	13	23

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S847. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRKAR1A MUTATED	1	3	3
PRKAR1A WILD-TYPE	22	30	19

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S848. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRKAR1A MUTATED	5	1	1
PRKAR1A WILD-TYPE	32	15	25

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S849. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRKAR1A MUTATED	2	0	5
PRKAR1A WILD-TYPE	24	10	38

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S850. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRKAR1A MUTATED	5	2	0
PRKAR1A WILD-TYPE	33	16	23

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S851. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRKAR1A MUTATED	5	0	2
PRKAR1A WILD-TYPE	36	11	25

'ATOH8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S852. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATOH8 MUTATED	2	0	1	1	0
ATOH8 WILD-TYPE	30	23	14	9	9

'ATOH8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S853. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATOH8 MUTATED	0	0	1	1	1
ATOH8 WILD-TYPE	18	11	20	17	10

'ATOH8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S854. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATOH8 MUTATED	1	0	1	1
ATOH8 WILD-TYPE	23	14	16	22

'ATOH8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S855. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATOH8 MUTATED	1	1	1
ATOH8 WILD-TYPE	22	32	21

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S856. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATOH8 MUTATED	2	0	1
ATOH8 WILD-TYPE	35	16	25

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S857. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATOH8 MUTATED	0	1	2
ATOH8 WILD-TYPE	26	9	41

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S858. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATOH8 MUTATED	2	0	1
ATOH8 WILD-TYPE	36	18	22

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S859. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATOH8 MUTATED	2	1	0
ATOH8 WILD-TYPE	39	10	27

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Chi-square test), Q value = 1

Table S860. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BTBD11 MUTATED	2	3	3	1	0
BTBD11 WILD-TYPE	30	20	12	9	9

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S861. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BTBD11 MUTATED	2	1	2	1	2
BTBD11 WILD-TYPE	16	10	19	17	9

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S862. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BTBD11 MUTATED	1	1	4	2
BTBD11 WILD-TYPE	23	13	13	21

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S863. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BTBD11 MUTATED	1	3	4
BTBD11 WILD-TYPE	22	30	18

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S864. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	32	15	24

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S865. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BTBD11 MUTATED	2	1	5
BTBD11 WILD-TYPE	24	9	38

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S866. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	33	17	21

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S867. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	36	10	25

'KANK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0378 (Chi-square test), Q value = 1

Table S868. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KANK3 MUTATED	0	1	3	2	0
KANK3 WILD-TYPE	32	22	12	8	9

Figure S62. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KANK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.532 (Chi-square test), Q value = 1

Table S869. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KANK3 MUTATED	2	0	2	0	1
KANK3 WILD-TYPE	16	11	19	18	10

'KANK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.048 (Fisher's exact test), Q value = 1

Table S870. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KANK3 MUTATED	1	3	1	0
KANK3 WILD-TYPE	23	11	16	23

Figure S63. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'KANK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0108 (Fisher's exact test), Q value = 1

Table S871. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KANK3 MUTATED	1	0	4
KANK3 WILD-TYPE	22	33	18

Figure S64. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KANK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0573 (Fisher's exact test), Q value = 1

Table S872. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KANK3 MUTATED	2	3	0
KANK3 WILD-TYPE	35	13	26

'KANK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S873. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KANK3 MUTATED	2	0	3
KANK3 WILD-TYPE	24	10	40

'KANK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 1

Table S874. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KANK3 MUTATED	2	3	0
KANK3 WILD-TYPE	36	15	23

'KANK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KANK3 MUTATED	3	0	2
KANK3 WILD-TYPE	38	11	25

'PAQR4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S876. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PAQR4 MUTATED	1	1	1	0	0
PAQR4 WILD-TYPE	31	22	14	10	9

'PAQR4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S877. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PAQR4 MUTATED	1	0	1	1	0
PAQR4 WILD-TYPE	17	11	20	17	11

'PAQR4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S878. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PAQR4 MUTATED	1	1	0	1
PAQR4 WILD-TYPE	23	13	17	22

'PAQR4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S879. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PAQR4 MUTATED	1	1	1
PAQR4 WILD-TYPE	22	32	21

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S880. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PAQR4 MUTATED	1	1	1
PAQR4 WILD-TYPE	36	15	25

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S881. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PAQR4 MUTATED	1	0	2
PAQR4 WILD-TYPE	25	10	41

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S882. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PAQR4 MUTATED	2	0	1
PAQR4 WILD-TYPE	36	18	22

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S883. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PAQR4 MUTATED	2	0	1
PAQR4 WILD-TYPE	39	11	26

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Chi-square test), Q value = 1

Table S884. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOM1 MUTATED	2	3	1	1	0
NOM1 WILD-TYPE	30	20	14	9	9

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Chi-square test), Q value = 1

Table S885. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOM1 MUTATED	1	1	1	1	2
NOM1 WILD-TYPE	17	10	20	17	9

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S886. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOM1 MUTATED	2	0	1	3
NOM1 WILD-TYPE	22	14	16	20

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S887. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOM1 MUTATED	2	3	1
NOM1 WILD-TYPE	21	30	21

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S888. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	35	15	23

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S889. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	24	9	40

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S890. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	36	17	20

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S891. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOM1 MUTATED	3	1	2
NOM1 WILD-TYPE	38	10	25

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Chi-square test), Q value = 1

Table S892. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PLIN5 MUTATED	1	4	0	1	0
PLIN5 WILD-TYPE	31	19	15	9	9

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S893. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PLIN5 MUTATED	1	2	1	2	0
PLIN5 WILD-TYPE	17	9	20	16	11

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S894. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PLIN5 MUTATED	1	1	2	2
PLIN5 WILD-TYPE	23	13	15	21

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S895. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PLIN5 MUTATED	1	2	3
PLIN5 WILD-TYPE	22	31	19

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S896. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PLIN5 MUTATED	1	2	3
PLIN5 WILD-TYPE	36	14	23

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0402 (Fisher's exact test), Q value = 1

Table S897. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PLIN5 MUTATED	5	0	1
PLIN5 WILD-TYPE	21	10	42

Figure S65. Get High-res Image Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S898. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PLIN5 MUTATED	1	3	2
PLIN5 WILD-TYPE	37	15	21

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S899. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PLIN5 MUTATED	1	0	5
PLIN5 WILD-TYPE	40	11	22

Figure S66. Get High-res Image Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.72 (Chi-square test), Q value = 1

Table S900. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CD320 MUTATED	3	1	1	0	0
CD320 WILD-TYPE	29	22	14	10	9

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S901. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CD320 MUTATED	2	0	1	2	0
CD320 WILD-TYPE	16	11	20	16	11

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S902. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CD320 MUTATED	2	0	2	1
CD320 WILD-TYPE	22	14	15	22

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S903. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CD320 MUTATED	2	2	1
CD320 WILD-TYPE	21	31	21

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S904. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CD320 MUTATED	4	1	0
CD320 WILD-TYPE	33	15	26

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S905. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CD320 MUTATED	0	0	5
CD320 WILD-TYPE	26	10	38

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0756 (Fisher's exact test), Q value = 1

Table S906. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CD320 MUTATED	5	0	0
CD320 WILD-TYPE	33	18	23

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S907. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CD320 MUTATED	5	0	0
CD320 WILD-TYPE	36	11	27

'AVL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.25 (Chi-square test), Q value = 1

Table S908. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AVL9 MUTATED	2	2	0	0	2
AVL9 WILD-TYPE	30	21	15	10	7

'AVL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.381 (Chi-square test), Q value = 1

Table S909. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AVL9 MUTATED	2	1	0	0	1
AVL9 WILD-TYPE	16	10	21	18	10

'AVL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S910. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AVL9 MUTATED	2	0	1	1
AVL9 WILD-TYPE	22	14	16	22

'AVL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S911. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	21	32	21

'AVL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S912. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	35	15	25

'AVL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S913. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AVL9 MUTATED	1	1	2
AVL9 WILD-TYPE	25	9	41

'AVL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S914. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	36	17	22

'AVL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S915. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	39	10	26

'ASB16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.808 (Chi-square test), Q value = 1

Table S916. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ASB16 MUTATED	3	3	1	1	2
ASB16 WILD-TYPE	29	20	14	9	7

'ASB16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.947 (Chi-square test), Q value = 1

Table S917. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ASB16 MUTATED	2	1	1	1	1
ASB16 WILD-TYPE	16	10	20	17	10

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S918. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ASB16 MUTATED	2	1	0	3
ASB16 WILD-TYPE	22	13	17	20

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S919. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ASB16 MUTATED	2	3	1
ASB16 WILD-TYPE	21	30	21

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S920. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	34	15	24

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S921. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ASB16 MUTATED	2	1	3
ASB16 WILD-TYPE	24	9	40

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S922. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	35	17	21

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S923. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	38	10	25

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.616 (Chi-square test), Q value = 1

Table S924. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SCRT1 MUTATED	1	2	2	1	0
SCRT1 WILD-TYPE	31	21	13	9	9

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.345 (Chi-square test), Q value = 1

Table S925. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SCRT1 MUTATED	3	0	1	2	0
SCRT1 WILD-TYPE	15	11	20	16	11

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S926. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SCRT1 MUTATED	2	2	1	1
SCRT1 WILD-TYPE	22	12	16	22

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S927. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SCRT1 MUTATED	2	2	2
SCRT1 WILD-TYPE	21	31	20

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S928. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SCRT1 MUTATED	3	2	1
SCRT1 WILD-TYPE	34	14	25

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S929. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SCRT1 MUTATED	3	0	3
SCRT1 WILD-TYPE	23	10	40

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S930. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SCRT1 MUTATED	3	2	1
SCRT1 WILD-TYPE	35	16	22

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S931. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SCRT1 MUTATED	3	0	3
SCRT1 WILD-TYPE	38	11	24

'FOXQ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0765 (Chi-square test), Q value = 1

Table S932. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FOXQ1 MUTATED	1	0	0	2	1
FOXQ1 WILD-TYPE	31	23	15	8	8

'FOXQ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0866 (Chi-square test), Q value = 1

Table S933. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FOXQ1 MUTATED	0	0	1	0	2
FOXQ1 WILD-TYPE	18	11	20	18	9

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S934. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FOXQ1 MUTATED	1	0	1	1
FOXQ1 WILD-TYPE	23	14	16	22

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S935. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FOXQ1 MUTATED	1	2	0
FOXQ1 WILD-TYPE	22	31	22

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S936. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FOXQ1 MUTATED	1	0	2
FOXQ1 WILD-TYPE	36	16	24

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S937. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FOXQ1 MUTATED	2	0	1
FOXQ1 WILD-TYPE	24	10	42

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S938. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FOXQ1 MUTATED	1	1	1
FOXQ1 WILD-TYPE	37	17	22

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S939. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FOXQ1 MUTATED	1	0	2
FOXQ1 WILD-TYPE	40	11	25

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.101 (Chi-square test), Q value = 1

Table S940. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NPTX1 MUTATED	5	0	0	0	1
NPTX1 WILD-TYPE	27	23	15	10	8

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S941. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NPTX1 MUTATED	1	1	1	3	0
NPTX1 WILD-TYPE	17	10	20	15	11

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S942. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NPTX1 MUTATED	2	0	1	3
NPTX1 WILD-TYPE	22	14	16	20

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S943. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NPTX1 MUTATED	2	4	0
NPTX1 WILD-TYPE	21	29	22

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S944. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NPTX1 MUTATED	3	0	3
NPTX1 WILD-TYPE	34	16	23

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S945. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NPTX1 MUTATED	1	2	3
NPTX1 WILD-TYPE	25	8	40

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S946. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NPTX1 MUTATED	3	0	3
NPTX1 WILD-TYPE	35	18	20

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0522 (Fisher's exact test), Q value = 1

Table S947. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NPTX1 MUTATED	2	3	1
NPTX1 WILD-TYPE	39	8	26

'ZNF285 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.526 (Chi-square test), Q value = 1

Table S948. Gene #122: 'ZNF285 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF285 MUTATED	1	2	0	0	0
ZNF285 WILD-TYPE	31	21	15	10	9

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.243 (Chi-square test), Q value = 1

Table S949. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PTPLA MUTATED	3	0	1	2	0
PTPLA WILD-TYPE	29	23	14	8	9

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S950. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PTPLA MUTATED	1	1	3	0	0
PTPLA WILD-TYPE	17	10	18	18	11

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S951. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PTPLA MUTATED	2	0	2	1
PTPLA WILD-TYPE	22	14	15	22

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S952. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PTPLA MUTATED	2	1	2
PTPLA WILD-TYPE	21	32	20

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S953. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PTPLA MUTATED	2	1	2
PTPLA WILD-TYPE	35	15	24

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S954. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PTPLA MUTATED	2	0	3
PTPLA WILD-TYPE	24	10	40

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S955. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PTPLA MUTATED	2	2	1
PTPLA WILD-TYPE	36	16	22

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S956. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PTPLA MUTATED	3	0	2
PTPLA WILD-TYPE	38	11	25

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.439 (Chi-square test), Q value = 1

Table S957. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRSS27 MUTATED	1	1	2	0	0
PRSS27 WILD-TYPE	31	22	13	10	9

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S958. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRSS27 MUTATED	0	1	2	1	0
PRSS27 WILD-TYPE	18	10	19	17	11

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S959. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRSS27 MUTATED	1	2	1	0
PRSS27 WILD-TYPE	23	12	16	23

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S960. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRSS27 MUTATED	0	1	3
PRSS27 WILD-TYPE	23	32	19

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S961. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRSS27 MUTATED	2	2	0
PRSS27 WILD-TYPE	35	14	26

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S962. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRSS27 MUTATED	1	0	3
PRSS27 WILD-TYPE	25	10	40

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S963. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRSS27 MUTATED	2	2	0
PRSS27 WILD-TYPE	36	16	23

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S964. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRSS27 MUTATED	2	0	2
PRSS27 WILD-TYPE	39	11	25

'LRRN4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.838 (Chi-square test), Q value = 1

Table S965. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRRN4 MUTATED	1	1	1	1	0
LRRN4 WILD-TYPE	31	22	14	9	9

'LRRN4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.51 (Chi-square test), Q value = 1

Table S966. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRRN4 MUTATED	0	0	1	2	1
LRRN4 WILD-TYPE	18	11	20	16	10

'LRRN4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S967. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRRN4 MUTATED	2	1	0	1
LRRN4 WILD-TYPE	22	13	17	22

'LRRN4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S968. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRRN4 MUTATED	1	2	1
LRRN4 WILD-TYPE	22	31	21

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S969. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRRN4 MUTATED	3	1	0
LRRN4 WILD-TYPE	34	15	26

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S970. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRRN4 MUTATED	0	0	4
LRRN4 WILD-TYPE	26	10	39

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S971. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRRN4 MUTATED	3	1	0
LRRN4 WILD-TYPE	35	17	23

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S972. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRRN4 MUTATED	3	0	1
LRRN4 WILD-TYPE	38	11	26

'EP400 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S973. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
EP400 MUTATED	1	1	1	0	0
EP400 WILD-TYPE	31	22	14	10	9

'EP400 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S974. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
EP400 MUTATED	1	0	2	1	0
EP400 WILD-TYPE	17	11	19	17	11

'EP400 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S975. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
EP400 MUTATED	1	2	0	1
EP400 WILD-TYPE	23	12	17	22

'EP400 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S976. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
EP400 MUTATED	1	1	2
EP400 WILD-TYPE	22	32	20

'EP400 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S977. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
EP400 MUTATED	2	1	1
EP400 WILD-TYPE	35	15	25

'EP400 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S978. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
EP400 MUTATED	2	0	2
EP400 WILD-TYPE	24	10	41

'EP400 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S979. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
EP400 MUTATED	2	1	1
EP400 WILD-TYPE	36	17	22

'EP400 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S980. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
EP400 MUTATED	2	0	2
EP400 WILD-TYPE	39	11	25

'LTK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.863 (Chi-square test), Q value = 1

Table S981. Gene #127: 'LTK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LTK MUTATED	2	1	1	0	0
LTK WILD-TYPE	30	22	14	10	9

'CCDC96 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.103 (Chi-square test), Q value = 1

Table S982. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC96 MUTATED	0	1	1	2	0
CCDC96 WILD-TYPE	32	22	14	8	9

'CCDC96 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S983. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC96 MUTATED	0	0	2	1	1
CCDC96 WILD-TYPE	18	11	19	17	10

'CCDC96 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S984. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC96 MUTATED	1	1	1	1
CCDC96 WILD-TYPE	23	13	16	22

'CCDC96 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S985. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC96 MUTATED	1	1	2
CCDC96 WILD-TYPE	22	32	20

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S986. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC96 MUTATED	2	1	1
CCDC96 WILD-TYPE	35	15	25

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S987. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC96 MUTATED	1	0	3
CCDC96 WILD-TYPE	25	10	40

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S988. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC96 MUTATED	2	1	1
CCDC96 WILD-TYPE	36	17	22

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S989. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC96 MUTATED	3	0	1
CCDC96 WILD-TYPE	38	11	26

'PCMTD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.257 (Chi-square test), Q value = 1

Table S990. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PCMTD1 MUTATED	0	2	0	1	0
PCMTD1 WILD-TYPE	32	21	15	9	9

'PCMTD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.21 (Chi-square test), Q value = 1

Table S991. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PCMTD1 MUTATED	0	0	3	1	0
PCMTD1 WILD-TYPE	18	11	18	17	11

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S992. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PCMTD1 MUTATED	0	1	2	1
PCMTD1 WILD-TYPE	24	13	15	22

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S993. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PCMTD1 MUTATED	0	2	2
PCMTD1 WILD-TYPE	23	31	20

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S994. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PCMTD1 MUTATED	2	1	1
PCMTD1 WILD-TYPE	35	15	25

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S995. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PCMTD1 MUTATED	2	0	2
PCMTD1 WILD-TYPE	24	10	41

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S996. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PCMTD1 MUTATED	2	1	1
PCMTD1 WILD-TYPE	36	17	22

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S997. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PCMTD1 MUTATED	2	0	2
PCMTD1 WILD-TYPE	39	11	25

'GLI3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.731 (Chi-square test), Q value = 1

Table S998. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLI3 MUTATED	4	2	0	1	1
GLI3 WILD-TYPE	28	21	15	9	8

'GLI3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.217 (Chi-square test), Q value = 1

Table S999. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLI3 MUTATED	2	0	0	3	2
GLI3 WILD-TYPE	16	11	21	15	9

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S1000. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLI3 MUTATED	2	0	2	3
GLI3 WILD-TYPE	22	14	15	20

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S1001. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLI3 MUTATED	2	5	0
GLI3 WILD-TYPE	21	28	22

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S1002. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLI3 MUTATED	5	0	2
GLI3 WILD-TYPE	32	16	24

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S1003. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLI3 MUTATED	2	0	5
GLI3 WILD-TYPE	24	10	38

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S1004. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLI3 MUTATED	5	1	1
GLI3 WILD-TYPE	33	17	22

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1005. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLI3 MUTATED	4	1	2
GLI3 WILD-TYPE	37	10	25

'MN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.767 (Chi-square test), Q value = 1

Table S1006. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MN1 MUTATED	2	2	2	2	1
MN1 WILD-TYPE	30	21	13	8	8

'MN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.264 (Chi-square test), Q value = 1

Table S1007. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MN1 MUTATED	2	0	2	1	3
MN1 WILD-TYPE	16	11	19	17	8

'MN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S1008. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MN1 MUTATED	3	1	1	3
MN1 WILD-TYPE	21	13	16	20

'MN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S1009. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MN1 MUTATED	3	3	2
MN1 WILD-TYPE	20	30	20

'MN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S1010. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MN1 MUTATED	5	0	3
MN1 WILD-TYPE	32	16	23

'MN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S1011. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MN1 MUTATED	1	2	5
MN1 WILD-TYPE	25	8	38

'MN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S1012. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MN1 MUTATED	5	0	3
MN1 WILD-TYPE	33	18	20

'MN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S1013. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MN1 MUTATED	5	2	1
MN1 WILD-TYPE	36	9	26

'C9ORF66 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.51 (Chi-square test), Q value = 1

Table S1014. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C9ORF66 MUTATED	1	3	2	1	0
C9ORF66 WILD-TYPE	31	20	13	9	9

'C9ORF66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.947 (Chi-square test), Q value = 1

Table S1015. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C9ORF66 MUTATED	1	1	1	2	1
C9ORF66 WILD-TYPE	17	10	20	16	10

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1016. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C9ORF66 MUTATED	2	2	1	1
C9ORF66 WILD-TYPE	22	12	16	22

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1017. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C9ORF66 MUTATED	1	2	3
C9ORF66 WILD-TYPE	22	31	19

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S1018. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C9ORF66 MUTATED	3	2	1
C9ORF66 WILD-TYPE	34	14	25

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1019. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C9ORF66 MUTATED	2	0	4
C9ORF66 WILD-TYPE	24	10	39

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1020. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C9ORF66 MUTATED	3	2	1
C9ORF66 WILD-TYPE	35	16	22

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S1021. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C9ORF66 MUTATED	3	0	3
C9ORF66 WILD-TYPE	38	11	24

'MADCAM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0541 (Chi-square test), Q value = 1

Table S1022. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MADCAM1 MUTATED	0	2	3	0	0
MADCAM1 WILD-TYPE	32	21	12	10	9

'MADCAM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S1023. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MADCAM1 MUTATED	1	0	2	1	1
MADCAM1 WILD-TYPE	17	11	19	17	10

'MADCAM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S1024. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MADCAM1 MUTATED	0	1	2	1
MADCAM1 WILD-TYPE	24	13	15	22

'MADCAM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S1025. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MADCAM1 MUTATED	0	2	2
MADCAM1 WILD-TYPE	23	31	20

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S1026. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MADCAM1 MUTATED	4	0	1
MADCAM1 WILD-TYPE	33	16	25

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S1027. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MADCAM1 MUTATED	0	1	4
MADCAM1 WILD-TYPE	26	9	39

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S1028. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MADCAM1 MUTATED	4	0	1
MADCAM1 WILD-TYPE	34	18	22

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S1029. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MADCAM1 MUTATED	4	1	0
MADCAM1 WILD-TYPE	37	10	27

'BMP8A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.387 (Chi-square test), Q value = 1

Table S1030. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BMP8A MUTATED	2	0	0	0	1
BMP8A WILD-TYPE	30	23	15	10	8

'BMP8A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S1031. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BMP8A MUTATED	1	0	0	1	1
BMP8A WILD-TYPE	17	11	21	17	10

'BMP8A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1032. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BMP8A MUTATED	1	0	1	1
BMP8A WILD-TYPE	23	14	16	22

'BMP8A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1033. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BMP8A MUTATED	1	2	0
BMP8A WILD-TYPE	22	31	22

'BMP8A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1034. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BMP8A MUTATED	2	0	1
BMP8A WILD-TYPE	35	16	25

'BMP8A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1035. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BMP8A MUTATED	1	0	2
BMP8A WILD-TYPE	25	10	41

'BMP8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S1036. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BMP8A MUTATED	2	1	0
BMP8A WILD-TYPE	36	17	23

'BMP8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S1037. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BMP8A MUTATED	1	1	1
BMP8A WILD-TYPE	40	10	26

'ODF3L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S1038. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ODF3L2 MUTATED	1	1	1	0	0
ODF3L2 WILD-TYPE	31	22	14	10	9

'ODF3L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S1039. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ODF3L2 MUTATED	1	0	0	1	1
ODF3L2 WILD-TYPE	17	11	21	17	10

'ODF3L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S1040. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ODF3L2 MUTATED	2	0	0	1
ODF3L2 WILD-TYPE	22	14	17	22

'ODF3L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1041. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ODF3L2 MUTATED	1	2	0
ODF3L2 WILD-TYPE	22	31	22

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1042. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ODF3L2 MUTATED	1	1	1
ODF3L2 WILD-TYPE	36	15	25

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1043. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ODF3L2 MUTATED	2	0	1
ODF3L2 WILD-TYPE	24	10	42

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1044. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ODF3L2 MUTATED	1	1	1
ODF3L2 WILD-TYPE	37	17	22

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1045. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ODF3L2 MUTATED	1	0	2
ODF3L2 WILD-TYPE	40	11	25

'QRICH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Chi-square test), Q value = 1

Table S1046. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
QRICH2 MUTATED	2	1	0	1	0
QRICH2 WILD-TYPE	30	22	15	9	9

'QRICH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.635 (Chi-square test), Q value = 1

Table S1047. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
QRICH2 MUTATED	2	0	1	1	0
QRICH2 WILD-TYPE	16	11	20	17	11

'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S1048. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
QRICH2 MUTATED	2	0	2	0
QRICH2 WILD-TYPE	22	14	15	23

'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1049. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
QRICH2 MUTATED	2	2	0
QRICH2 WILD-TYPE	21	31	22

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S1050. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
QRICH2 MUTATED	2	0	2
QRICH2 WILD-TYPE	35	16	24

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S1051. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
QRICH2 MUTATED	1	1	2
QRICH2 WILD-TYPE	25	9	41

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S1052. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
QRICH2 MUTATED	2	0	2
QRICH2 WILD-TYPE	36	18	21

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S1053. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
QRICH2 MUTATED	2	1	1
QRICH2 WILD-TYPE	39	10	26

'KRTAP10-7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S1054. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP10-7 MUTATED	2	2	0	1	0
KRTAP10-7 WILD-TYPE	30	21	15	9	9

'KRTAP10-7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S1055. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP10-7 MUTATED	0	1	3	1	0
KRTAP10-7 WILD-TYPE	18	10	18	17	11

'KRTAP10-7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S1056. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP10-7 MUTATED	1	1	2	1
KRTAP10-7 WILD-TYPE	23	13	15	22

'KRTAP10-7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1057. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP10-7 MUTATED	1	2	2
KRTAP10-7 WILD-TYPE	22	31	20

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0163 (Fisher's exact test), Q value = 1

Table S1058. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP10-7 MUTATED	0	3	2
KRTAP10-7 WILD-TYPE	37	13	24

Figure S67. Get High-res Image Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S1059. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP10-7 MUTATED	1	2	2
KRTAP10-7 WILD-TYPE	25	8	41

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0264 (Fisher's exact test), Q value = 1

Table S1060. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP10-7 MUTATED	0	3	2
KRTAP10-7 WILD-TYPE	38	15	21

Figure S68. Get High-res Image Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S1061. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP10-7 MUTATED	2	2	1
KRTAP10-7 WILD-TYPE	39	9	26

'IDI1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Chi-square test), Q value = 1

Table S1062. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IDI1 MUTATED	2	1	2	0	0
IDI1 WILD-TYPE	30	22	13	10	9

'IDI1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S1063. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IDI1 MUTATED	2	0	1	2	0
IDI1 WILD-TYPE	16	11	20	16	11

'IDI1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S1064. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IDI1 MUTATED	1	2	1	1
IDI1 WILD-TYPE	23	12	16	22

'IDI1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1065. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IDI1 MUTATED	1	2	2
IDI1 WILD-TYPE	22	31	20

'IDI1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1066. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IDI1 MUTATED	2	1	2
IDI1 WILD-TYPE	35	15	24

'IDI1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S1067. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IDI1 MUTATED	3	0	2
IDI1 WILD-TYPE	23	10	41

'IDI1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S1068. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IDI1 MUTATED	2	1	2
IDI1 WILD-TYPE	36	17	21

'IDI1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S1069. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IDI1 MUTATED	2	0	3
IDI1 WILD-TYPE	39	11	24

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.237 (Chi-square test), Q value = 1

Table S1070. Gene #139: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IER5 MUTATED	3	0	0	0	0
IER5 WILD-TYPE	29	23	15	10	9

'PRR21 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.585 (Chi-square test), Q value = 1

Table S1071. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRR21 MUTATED	2	3	1	0	0
PRR21 WILD-TYPE	30	20	14	10	9

'PRR21 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.684 (Chi-square test), Q value = 1

Table S1072. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRR21 MUTATED	0	1	1	2	1
PRR21 WILD-TYPE	18	10	20	16	10

'PRR21 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S1073. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRR21 MUTATED	2	1	0	2
PRR21 WILD-TYPE	22	13	17	21

'PRR21 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S1074. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRR21 MUTATED	1	3	1
PRR21 WILD-TYPE	22	30	21

'PRR21 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1075. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	35	15	24

'PRR21 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1076. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	24	9	41

'PRR21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S1077. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	36	17	21

'PRR21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S1078. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	39	10	25

'ARRDC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.465 (Chi-square test), Q value = 1

Table S1079. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ARRDC4 MUTATED	4	1	2	0	0
ARRDC4 WILD-TYPE	28	22	13	10	9

'ARRDC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.334 (Chi-square test), Q value = 1

Table S1080. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ARRDC4 MUTATED	2	2	2	0	0
ARRDC4 WILD-TYPE	16	9	19	18	11

'ARRDC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S1081. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ARRDC4 MUTATED	3	1	2	0
ARRDC4 WILD-TYPE	21	13	15	23

'ARRDC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S1082. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ARRDC4 MUTATED	4	1	1
ARRDC4 WILD-TYPE	19	32	21

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S1083. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ARRDC4 MUTATED	3	2	1
ARRDC4 WILD-TYPE	34	14	25

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S1084. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ARRDC4 MUTATED	1	1	4
ARRDC4 WILD-TYPE	25	9	39

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1085. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ARRDC4 MUTATED	3	2	1
ARRDC4 WILD-TYPE	35	16	22

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S1086. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ARRDC4 MUTATED	4	1	1
ARRDC4 WILD-TYPE	37	10	26

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S1087. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF135 MUTATED	1	2	1	0	0
RNF135 WILD-TYPE	31	21	14	10	9

'RNF135 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.344 (Chi-square test), Q value = 1

Table S1088. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF135 MUTATED	1	0	0	2	0
RNF135 WILD-TYPE	17	11	21	16	11

'RNF135 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S1089. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF135 MUTATED	0	1	0	2
RNF135 WILD-TYPE	24	13	17	21

'RNF135 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S1090. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF135 MUTATED	0	2	1
RNF135 WILD-TYPE	23	31	21

'RNF135 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1091. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF135 MUTATED	1	1	1
RNF135 WILD-TYPE	36	15	25

'RNF135 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1092. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF135 MUTATED	2	0	1
RNF135 WILD-TYPE	24	10	42

'RNF135 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1093. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF135 MUTATED	1	1	1
RNF135 WILD-TYPE	37	17	22

'RNF135 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1094. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF135 MUTATED	1	0	2
RNF135 WILD-TYPE	40	11	25

'DAXX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0325 (Chi-square test), Q value = 1

Table S1095. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DAXX MUTATED	1	0	3	0	0
DAXX WILD-TYPE	31	23	12	10	9

Figure S69. Get High-res Image Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'DAXX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.21 (Chi-square test), Q value = 1

Table S1096. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DAXX MUTATED	1	0	3	0	0
DAXX WILD-TYPE	17	11	18	18	11

'DAXX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S1097. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DAXX MUTATED	1	2	1	0
DAXX WILD-TYPE	23	12	16	23

'DAXX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S1098. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DAXX MUTATED	1	0	3
DAXX WILD-TYPE	22	33	19

Figure S70. Get High-res Image Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'DAXX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S1099. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DAXX MUTATED	3	1	0
DAXX WILD-TYPE	34	15	26

'DAXX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1100. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DAXX MUTATED	1	0	3
DAXX WILD-TYPE	25	10	40

'DAXX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S1101. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DAXX MUTATED	3	1	0
DAXX WILD-TYPE	35	17	23

'DAXX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1102. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DAXX MUTATED	3	0	1
DAXX WILD-TYPE	38	11	26

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.749 (Chi-square test), Q value = 1

Table S1103. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
VARS MUTATED	2	2	1	2	1
VARS WILD-TYPE	30	21	14	8	8

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.931 (Chi-square test), Q value = 1

Table S1104. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
VARS MUTATED	1	1	3	2	1
VARS WILD-TYPE	17	10	18	16	10

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S1105. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
VARS MUTATED	2	0	4	2
VARS WILD-TYPE	22	14	13	21

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S1106. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
VARS MUTATED	1	3	4
VARS WILD-TYPE	22	30	18

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S1107. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
VARS MUTATED	2	3	3
VARS WILD-TYPE	35	13	23

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1108. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
VARS MUTATED	3	1	4
VARS WILD-TYPE	23	9	39

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S1109. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
VARS MUTATED	2	4	2
VARS WILD-TYPE	36	14	21

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S1110. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
VARS MUTATED	3	1	4
VARS WILD-TYPE	38	10	23

'GPR20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S1111. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GPR20 MUTATED	2	0	1	1	0
GPR20 WILD-TYPE	30	23	14	9	9

'GPR20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S1112. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GPR20 MUTATED	1	0	1	0	1
GPR20 WILD-TYPE	17	11	20	18	10

'GPR20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S1113. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GPR20 MUTATED	1	0	2	0
GPR20 WILD-TYPE	23	14	15	23

'GPR20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1114. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GPR20 MUTATED	1	1	1
GPR20 WILD-TYPE	22	32	21

'GPR20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S1115. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GPR20 MUTATED	2	1	0
GPR20 WILD-TYPE	35	15	26

'GPR20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1116. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GPR20 MUTATED	1	0	2
GPR20 WILD-TYPE	25	10	41

'GPR20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S1117. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GPR20 MUTATED	2	1	0
GPR20 WILD-TYPE	36	17	23

'GPR20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1118. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GPR20 MUTATED	2	0	1
GPR20 WILD-TYPE	39	11	26

'SAMD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.433 (Chi-square test), Q value = 1

Table S1119. Gene #146: 'SAMD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SAMD11 MUTATED	2	0	0	1	0
SAMD11 WILD-TYPE	30	23	15	9	9

'DMWD MUTATION STATUS' versus 'CN_CNMF'

P value = 0.254 (Chi-square test), Q value = 1

Table S1120. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMWD MUTATED	1	0	2	0	1
DMWD WILD-TYPE	31	23	13	10	8

'DMWD MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.788 (Chi-square test), Q value = 1

Table S1121. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMWD MUTATED	1	1	1	0	1
DMWD WILD-TYPE	17	10	20	18	10

'DMWD MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1122. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMWD MUTATED	1	1	2	0
DMWD WILD-TYPE	23	13	15	23

'DMWD MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S1123. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMWD MUTATED	2	1	1
DMWD WILD-TYPE	21	32	21

'DMWD MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1124. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMWD MUTATED	2	1	1
DMWD WILD-TYPE	35	15	25

'DMWD MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1125. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMWD MUTATED	1	0	3
DMWD WILD-TYPE	25	10	40

'DMWD MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S1126. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMWD MUTATED	2	2	0
DMWD WILD-TYPE	36	16	23

'DMWD MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1127. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMWD MUTATED	3	0	1
DMWD WILD-TYPE	38	11	26

'KISS1R MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S1128. Gene #148: 'KISS1R MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KISS1R MUTATED	1	1	1	0	0
KISS1R WILD-TYPE	31	22	14	10	9

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Chi-square test), Q value = 1

Table S1129. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PLEC MUTATED	6	7	2	1	1
PLEC WILD-TYPE	26	16	13	9	8

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.75 (Chi-square test), Q value = 1

Table S1130. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PLEC MUTATED	4	3	2	3	2
PLEC WILD-TYPE	14	8	19	15	9

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S1131. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PLEC MUTATED	3	1	6	4
PLEC WILD-TYPE	21	13	11	19

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S1132. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PLEC MUTATED	3	7	4
PLEC WILD-TYPE	20	26	18

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S1133. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PLEC MUTATED	6	4	4
PLEC WILD-TYPE	31	12	22

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1134. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PLEC MUTATED	4	3	7
PLEC WILD-TYPE	22	7	36

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1135. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PLEC MUTATED	7	3	4
PLEC WILD-TYPE	31	15	19

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1136. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PLEC MUTATED	7	3	4
PLEC WILD-TYPE	34	8	23

'FAM110C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.723 (Chi-square test), Q value = 1

Table S1137. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FAM110C MUTATED	2	1	0	0	0
FAM110C WILD-TYPE	30	22	15	10	9

'FAM110C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S1138. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FAM110C MUTATED	1	1	1	0	0
FAM110C WILD-TYPE	17	10	20	18	11

'FAM110C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S1139. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FAM110C MUTATED	2	0	1	0
FAM110C WILD-TYPE	22	14	16	23

'FAM110C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S1140. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FAM110C MUTATED	2	1	0
FAM110C WILD-TYPE	21	32	22

'FAM110C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1141. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FAM110C MUTATED	2	0	1
FAM110C WILD-TYPE	35	16	25

'FAM110C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S1142. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FAM110C MUTATED	0	1	2
FAM110C WILD-TYPE	26	9	41

'FAM110C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1143. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FAM110C MUTATED	2	0	1
FAM110C WILD-TYPE	36	18	22

'FAM110C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S1144. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FAM110C MUTATED	2	1	0
FAM110C WILD-TYPE	39	10	27

'RCCD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S1145. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RCCD1 MUTATED	2	2	0	1	0
RCCD1 WILD-TYPE	30	21	15	9	9

'RCCD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.371 (Chi-square test), Q value = 1

Table S1146. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RCCD1 MUTATED	0	0	1	2	0
RCCD1 WILD-TYPE	18	11	20	16	11

'RCCD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1147. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RCCD1 MUTATED	0	0	1	2
RCCD1 WILD-TYPE	24	14	16	21

'RCCD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S1148. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RCCD1 MUTATED	0	2	1
RCCD1 WILD-TYPE	23	31	21

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1149. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	36	15	25

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1150. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RCCD1 MUTATED	1	0	2
RCCD1 WILD-TYPE	25	10	41

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1151. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	37	17	22

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S1152. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	40	10	26

Methods & Data

Input

Mutation data file = transformed.cor.cli.txt
Molecular subtypes file = ACC-TP.transferedmergedcluster.txt
Number of patients = 91
Number of significantly mutated genes = 151
Number of Molecular subtypes = 8
Exclude genes that fewer than K tumors have mutations, K = 3

Chi-square test

For multi-class clinical features (nominal or ordinal), Chi-square tests (Greenwood and Nikulin 1996) were used to estimate the P values using the 'chisq.test' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References

[1] Greenwood and Nikulin, A guide to chi-squared testing, Wiley, New York. ISBN 047155779X (1996)

[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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