		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	68 (13%)	443	0.00010081	0.0715	0.011935	1	0.95702	1	0.84833	1	0.86587	1	0.59441	1	0.69656	1	0.34903	1	0.86429	1	0.70252	1
1q gain	117 (23%)	394	6.88e-07	0.000517	1.7819e-08	1.36e-05	0.28948	1	0.65283	1	0.00021824	0.153	0.00033036	0.229	0.0017658	1	0.2313	1	0.0057873	1	0.038559	1
2p gain	90 (18%)	421	1.6009e-07	0.000122	7.3583e-11	5.72e-08	0.045176	1	0.69515	1	0.049429	1	0.034704	1	0.12493	1	0.47005	1	0.09978	1	0.81335	1
2q gain	69 (14%)	442	2.0381e-06	0.00151	2.6796e-10	2.08e-07	0.53354	1	0.81192	1	0.061878	1	0.030329	1	0.24344	1	1	1	0.14158	1	0.45728	1
3p gain	79 (15%)	432	0.0081509	1	0.00024817	0.173	0.067691	1	0.053103	1	0.0014122	0.938	0.0041075	1	0.0095135	1	0.16617	1	0.044388	1	0.1114	1
3q gain	249 (49%)	262	1.1515e-05	0.00842	4.4262e-07	0.000334	0.68263	1	0.72989	1	0.00066144	0.452	0.0018246	1	0.0012075	0.808	0.27231	1	0.079621	1	0.24745	1
4p gain	39 (8%)	472	0.0025768	1	7.0446e-05	0.0504	0.5761	1	0.8238	1	0.051825	1	0.057942	1	0.1172	1	0.16763	1	0.47295	1	0.2739	1
4q gain	35 (7%)	476	0.10767	1	0.40456	1	1	1	0.84745	1	0.62199	1	0.11579	1	0.91946	1	0.72192	1	0.94833	1	0.46779	1
5p gain	195 (38%)	316	9.2096e-12	7.2e-09	0.0036385	1	0.95817	1	0.60164	1	0.083876	1	0.22641	1	0.60461	1	1	1	0.93184	1	0.97844	1
5q gain	65 (13%)	446	0.032223	1	0.52032	1	0.59502	1	0.707	1	0.76904	1	0.89385	1	0.72847	1	0.33364	1	0.45056	1	0.50295	1
6p gain	80 (16%)	431	1.7901e-06	0.00133	0.003433	1	0.49218	1	0.56312	1	0.66557	1	0.71224	1	0.56712	1	0.44801	1	0.24727	1	0.45954	1
6q gain	61 (12%)	450	2.2384e-05	0.0163	0.041366	1	0.19677	1	0.12706	1	0.074462	1	0.022387	1	0.12466	1	0.67222	1	0.056938	1	0.25362	1
7p gain	180 (35%)	331	1.4389e-09	1.11e-06	7.5703e-10	5.86e-07	0.62432	1	0.52004	1	0.26927	1	0.14479	1	0.68582	1	0.92348	1	0.45239	1	0.85589	1
7q gain	123 (24%)	388	9.4127e-09	7.23e-06	2.988e-11	2.33e-08	0.17555	1	0.91277	1	0.48374	1	0.90284	1	0.0076004	1	0.45374	1	0.48648	1	0.29509	1
8p gain	148 (29%)	363	0.0016399	1	0.078771	1	0.5827	1	0.54171	1	0.3529	1	0.068561	1	0.67664	1	0.31394	1	0.46321	1	0.59045	1
8q gain	304 (59%)	207	3.5603e-07	0.00027	2.0322e-05	0.0148	0.081594	1	0.42634	1	0.11466	1	0.011245	1	0.08395	1	0.0066493	1	0.0075491	1	0.015499	1
9p gain	102 (20%)	409	3.1675e-18	2.52e-15	5.0641e-05	0.0364	0.50396	1	0.058342	1	0.0013933	0.928	0.0085085	1	0.0078637	1	1	1	0.058196	1	0.5584	1
9q gain	136 (27%)	375	4.1692e-14	3.29e-11	0.017806	1	0.129	1	0.20733	1	0.25131	1	0.11299	1	0.65166	1	0.91758	1	0.28638	1	0.67639	1
10p gain	40 (8%)	471	0.058722	1	2.4946e-06	0.00184	0.57872	1	0.5291	1	0.038313	1	0.0041969	1	0.046092	1	0.058863	1	0.87515	1	0.19475	1
10q gain	34 (7%)	477	0.00066525	0.454	0.30454	1	0.097263	1	0.34104	1	0.64915	1	0.38082	1	0.58651	1	0.4641	1	0.83795	1	0.33129	1
11p gain	65 (13%)	446	4.2695e-06	0.00314	7.5386e-06	0.00553	0.93006	1	0.89304	1	0.20949	1	0.036231	1	0.052751	1	0.094559	1	0.18809	1	0.42687	1
11q gain	70 (14%)	441	0.00016823	0.119	7.5831e-05	0.0541	0.52074	1	0.77962	1	0.22944	1	0.033061	1	0.29835	1	0.68819	1	0.89248	1	0.72524	1
12p gain	143 (28%)	368	7.8718e-13	6.17e-10	1.1295e-07	8.6e-05	0.016096	1	0.31798	1	0.015519	1	0.0096169	1	0.066211	1	0.68359	1	0.49794	1	0.53293	1
12q gain	87 (17%)	424	3.8065e-07	0.000288	0.00085121	0.578	0.11851	1	0.12446	1	0.084516	1	0.0052495	1	0.5725	1	0.71704	1	0.74886	1	0.48445	1
13q gain	56 (11%)	455	2.3132e-08	1.76e-05	0.00088583	0.6	0.58842	1	0.50238	1	0.014408	1	0.011601	1	0.24218	1	0.052982	1	0.27718	1	0.028513	1
14q gain	148 (29%)	363	8.8485e-13	6.93e-10	1.8773e-06	0.00139	0.21676	1	0.47922	1	0.014296	1	0.14804	1	0.017363	1	0.0033032	1	0.0076741	1	0.00089547	0.605
15q gain	71 (14%)	440	0.082378	1	0.019909	1	0.38116	1	0.85143	1	0.20636	1	0.070273	1	0.98023	1	0.35826	1	0.84677	1	0.3441	1
16p gain	104 (20%)	407	1.2856e-06	0.00096	2.3448e-06	0.00174	0.33161	1	0.93637	1	0.41003	1	0.57691	1	0.71421	1	1	1	0.55649	1	0.92071	1
16q gain	104 (20%)	407	1.226e-08	9.4e-06	5.6265e-06	0.00413	0.49887	1	0.82604	1	0.15137	1	0.43525	1	0.27145	1	0.067791	1	0.025792	1	0.12262	1
17p gain	66 (13%)	445	8.6668e-07	0.000651	3.0434e-06	0.00224	0.59659	1	0.31058	1	0.0075086	1	0.10165	1	0.086864	1	0.0082608	1	0.26532	1	0.08294	1
17q gain	84 (16%)	427	7.5739e-06	0.00554	0.00023868	0.167	0.57849	1	0.58345	1	0.12657	1	0.27193	1	0.48967	1	0.38551	1	0.95846	1	0.79184	1
18p gain	119 (23%)	392	7.2716e-13	5.71e-10	5.2185e-06	0.00384	0.33276	1	0.76945	1	0.36891	1	0.0007115	0.484	0.65696	1	0.91428	1	0.79383	1	0.58174	1
18q gain	48 (9%)	463	0.002259	1	1.8183e-05	0.0133	0.016803	1	0.40811	1	0.00020599	0.145	2.0916e-05	0.0152	5.0369e-05	0.0362	0.27252	1	0.012024	1	0.11253	1
19p gain	53 (10%)	458	0.0016946	1	3.0449e-07	0.000231	0.089235	1	0.068385	1	0.012203	1	0.0013758	0.919	0.00044244	0.306	0.05043	1	0.50353	1	0.34181	1
19q gain	74 (14%)	437	0.039775	1	5.5203e-05	0.0396	0.95592	1	0.39256	1	0.017596	1	0.0020213	1	0.00055715	0.383	0.09141	1	0.82963	1	0.26385	1
20p gain	188 (37%)	323	2.7308e-06	0.00202	1.0446e-06	0.000781	0.95062	1	0.12045	1	0.10154	1	0.10334	1	0.20373	1	0.0023215	1	0.019071	1	0.023348	1
20q gain	198 (39%)	313	6.2606e-09	4.81e-06	6.0076e-07	0.000452	0.83434	1	0.85702	1	0.10811	1	0.21904	1	0.17264	1	0.004782	1	0.0024965	1	0.0092521	1
21q gain	35 (7%)	476	0.046457	1	0.017213	1	0.015127	1	0.76785	1	0.0066498	1	0.0067671	1	0.10002	1	0.47586	1	0.69534	1	0.67217	1
22q gain	110 (22%)	401	1.8186e-06	0.00135	2.1538e-13	1.7e-10	0.1526	1	0.37624	1	0.28119	1	0.63252	1	0.0011305	0.759	0.57822	1	0.0026262	1	0.75961	1
xq gain	87 (17%)	424	1.4116e-06	0.00105	0.0033306	1	0.25074	1	0.75124	1	0.41473	1	0.42818	1	0.061862	1	0.22054	1	0.65402	1	0.31572	1
1p loss	52 (10%)	459	0.00018181	0.128	1.4488e-08	1.11e-05	0.019997	1	0.53815	1	0.003607	1	0.0058707	1	0.33799	1	0.53892	1	0.21196	1	0.38392	1
1q loss	35 (7%)	476	0.058028	1	0.12382	1	0.77998	1	0.69635	1	0.098035	1	0.22418	1	0.036951	1	0.02728	1	0.055448	1	0.45599	1
2p loss	33 (6%)	478	0.090314	1	0.0037391	1	0.15909	1	0.15253	1	0.10804	1	0.035626	1	0.036499	1	1	1	0.011774	1	0.82327	1
2q loss	42 (8%)	469	0.92168	1	0.038555	1	0.83585	1	0.17175	1	0.73794	1	0.70334	1	0.20668	1	1	1	0.030801	1	0.5135	1
3p loss	287 (56%)	224	2.2895e-26	1.83e-23	6.5167e-21	5.19e-18	0.82318	1	0.12039	1	0.013079	1	0.011789	1	0.14231	1	0.012742	1	0.72031	1	0.44345	1
3q loss	60 (12%)	451	0.013876	1	0.19244	1	0.2626	1	0.84354	1	0.60541	1	0.83364	1	0.9414	1	1	1	0.46461	1	0.79601	1
4p loss	186 (36%)	325	6.96e-20	5.54e-17	4.8469e-14	3.82e-11	0.039159	1	0.59242	1	0.00023096	0.162	6.2299e-05	0.0446	0.37748	1	0.56836	1	0.026957	1	0.022201	1
4q loss	144 (28%)	367	6.6289e-13	5.21e-10	5.019e-07	0.000378	0.46877	1	0.42742	1	0.0077563	1	0.0031926	1	0.23865	1	0.18434	1	0.079711	1	0.033151	1
5p loss	50 (10%)	461	1.5517e-05	0.0113	2.5055e-05	0.0181	0.40711	1	0.43377	1	0.68978	1	0.57802	1	0.76296	1	0.21862	1	0.12422	1	0.43472	1
5q loss	160 (31%)	351	2.3286e-21	1.86e-18	5.3757e-17	4.26e-14	0.24333	1	0.13299	1	0.20504	1	0.0013949	0.928	0.79909	1	0.092301	1	0.71813	1	0.656	1
6p loss	67 (13%)	444	0.0003012	0.209	0.0033866	1	0.029545	1	0.55503	1	0.029437	1	0.052086	1	0.32694	1	0.42007	1	0.2602	1	0.46784	1
6q loss	67 (13%)	444	0.065165	1	0.0095505	1	0.12835	1	0.38412	1	0.76904	1	0.15187	1	0.66977	1	0.49751	1	0.33462	1	0.63007	1
7p loss	28 (5%)	483	0.022189	1	0.041045	1	0.010206	1	0.20746	1	0.47156	1	0.16651	1	0.29964	1	0.84295	1	0.081639	1	0.75068	1
7q loss	42 (8%)	469	0.2016	1	0.38348	1	0.52519	1	0.27131	1	0.32352	1	0.72256	1	0.042263	1	0.50637	1	0.82856	1	0.78461	1
8p loss	184 (36%)	327	5.1771e-11	4.03e-08	2.0173e-06	0.0015	0.54953	1	0.28818	1	0.036355	1	0.00093843	0.633	0.030978	1	0.00056781	0.39	0.00089828	0.606	0.0008613	0.584
8q loss	30 (6%)	481	0.07668	1	0.13362	1	0.75617	1	0.34375	1	0.69792	1	0.79851	1	0.21651	1	1	1	0.74129	1	0.29449	1
9p loss	176 (34%)	335	4.3599e-26	3.48e-23	4.9014e-17	3.89e-14	0.69921	1	0.16434	1	0.29882	1	0.33033	1	0.41071	1	0.84712	1	0.33378	1	0.54824	1
9q loss	83 (16%)	428	2.5682e-10	1.99e-07	1.0203e-06	0.000764	0.98384	1	1	1	0.62424	1	0.84454	1	0.80558	1	0.61864	1	0.13541	1	0.25092	1
10p loss	151 (30%)	360	3.5372e-05	0.0256	0.00061827	0.423	0.31622	1	0.09801	1	0.051014	1	0.13183	1	0.097392	1	0.1077	1	0.24963	1	0.3015	1
10q loss	109 (21%)	402	0.00011333	0.0802	0.0011973	0.802	0.20753	1	0.33021	1	0.014863	1	0.10681	1	0.020854	1	0.82168	1	0.25372	1	0.79319	1
11p loss	134 (26%)	377	2.206e-08	1.69e-05	0.00035283	0.245	0.33024	1	0.90852	1	0.0051974	1	0.037435	1	0.006044	1	0.67815	1	0.38859	1	0.15533	1
11q loss	164 (32%)	347	8.5271e-05	0.0608	2.8491e-07	0.000216	0.25444	1	0.40883	1	0.0049871	1	0.0046944	1	0.26228	1	0.69564	1	0.38767	1	0.8664	1
12p loss	36 (7%)	475	0.64713	1	0.11058	1	0.6461	1	0.60528	1	0.85515	1	0.9231	1	1	1	0.58763	1	0.37049	1	0.64947	1
12q loss	32 (6%)	479	0.016322	1	0.016937	1	0.87131	1	0.26688	1	0.48934	1	0.40669	1	0.97241	1	0.70067	1	0.18654	1	0.49611	1
13q loss	162 (32%)	349	3.744e-15	2.96e-12	9.39e-07	0.000704	0.3772	1	0.80156	1	0.0031617	1	0.00028222	0.196	0.037151	1	0.4309	1	0.33627	1	0.056974	1
14q loss	54 (11%)	457	0.0062509	1	0.0021797	1	0.037227	1	0.41525	1	5.0343e-05	0.0362	0.0010996	0.74	0.0045499	1	0.05043	1	0.23458	1	0.04383	1
15q loss	98 (19%)	413	8.5134e-08	6.49e-05	0.2303	1	0.62524	1	0.41349	1	0.12133	1	0.067019	1	0.72062	1	0.24562	1	0.53106	1	0.35016	1
16p loss	60 (12%)	451	0.00048051	0.331	0.013226	1	0.86737	1	0.72313	1	0.0061866	1	0.06638	1	0.95308	1	0.31654	1	0.82623	1	0.6273	1
16q loss	78 (15%)	433	0.0057899	1	1.5458e-09	1.19e-06	0.47868	1	0.078006	1	1.9246e-10	1.5e-07	1.9268e-09	1.49e-06	0.0022495	1	0.01472	1	0.00056819	0.39	0.00036491	0.253
17p loss	103 (20%)	408	8.5845e-05	0.0611	0.0030679	1	0.39291	1	0.27806	1	0.52278	1	0.076265	1	0.53274	1	0.90979	1	0.2519	1	0.54284	1
17q loss	34 (7%)	477	0.0011234	0.755	0.32588	1	0.90272	1	0.0047845	1	0.4374	1	0.80718	1	0.90427	1	0.35509	1	0.96574	1	0.43321	1
18p loss	101 (20%)	410	0.022107	1	0.00019079	0.135	0.53643	1	0.20344	1	0.26974	1	0.11572	1	0.64432	1	0.24562	1	0.86146	1	0.32043	1
18q loss	208 (41%)	303	1.664e-17	1.32e-14	1.4262e-14	1.13e-11	0.31437	1	0.015061	1	0.0018781	1	0.00068755	0.468	0.0016301	1	0.00026405	0.184	0.14709	1	0.022768	1
19p loss	93 (18%)	418	0.00022879	0.16	2.3814e-05	0.0173	0.70291	1	0.2041	1	0.022682	1	0.10195	1	0.042049	1	0.0027039	1	0.65749	1	0.3289	1
19q loss	82 (16%)	429	9.7754e-05	0.0695	4.96e-05	0.0358	0.12921	1	0.55363	1	0.2088	1	0.67175	1	0.35285	1	0.031877	1	0.7826	1	0.62602	1
20p loss	46 (9%)	465	0.00046094	0.318	0.0062728	1	0.48302	1	0.47588	1	0.083748	1	0.087451	1	0.3359	1	0.034932	1	0.0014417	0.956	0.12189	1
20q loss	28 (5%)	483	0.010799	1	0.018227	1	0.22528	1	0.19148	1	0.02172	1	0.0073053	1	0.026744	1	0.027727	1	0.00019488	0.137	0.01461	1
21q loss	179 (35%)	332	2.6348e-11	2.06e-08	1.9568e-09	1.51e-06	0.57123	1	0.5117	1	0.032996	1	0.12025	1	0.5284	1	0.083702	1	0.72493	1	0.20652	1
22q loss	72 (14%)	439	0.0036418	1	0.003329	1	0.64405	1	0.53815	1	0.0013774	0.919	0.25974	1	0.00058191	0.399	0.1436	1	0.0034228	1	0.43339	1
xq loss	82 (16%)	429	9.793e-05	0.0695	3.6665e-05	0.0265	0.088194	1	0.033628	1	0.030549	1	0.020674	1	0.014837	1	0.3785	1	0.1685	1	0.22808	1
